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Contents Volume 14 Issue 4 December 9, 2025

Opinion Review

Giving urine biochemistry a second chance in acute kidney injury monitoring

Alexandre Toledo Maciel

World J Crit Care Med 14(4):109194. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.109194

Abstract (67) | Core Tip (83) | Full Article (HTML) (316) | Figures (1-2) (59) | Tables (1-2) (64) | Full Article (PDF)-1301K (70) | Full Article with Cover (PDF)-1622K (46) | Full Article (XML)-53K (29) | Audio-522K (16) | Peer-Review Report-259K (26) | Answering Reviewers-173K (36) | Received: 05/01/2025 | Revised: 06/04/2025 | Accepted: 07/22/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (1466) | Similar Articles (92) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Review

Thyroid storm-induced cardiovascular complications and modalities of therapy: Up-to-date review

Ayman El-Menyar, Naushad Ahmad Khan, Eman Elmenyar, Başar Cander, Lukasz Szarpak, Vimal Krishnan S, Sagar Galwnkar, Hassan Al-Thani

World J Crit Care Med 14(4):109565. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.109565

Abstract (78) | Core Tip (76) | Full Article (HTML) (2067) | Figures (1-4) (75) | Full Article (PDF)-2659K (522) | Full Article with Cover (PDF)-2976K (71) | Full Article (XML)-382K (32) | Audio-290K (12) | Peer-Review Report-209K (25) | Answering Reviewers-191K (24) | Received: 05/14/2025 | Revised: 05/22/2025 | Accepted: 08/05/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (4078) | Similar Articles (4) | Timeline of Article Publication (0) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Pathophysiology and management of right ventricular failure in critically ill patients: A narrative review

Riley Kermanian, Harpreet Dosanjh, Michael I Lewis, Yuri Matusov

World J Crit Care Med 14(4):111434. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.111434

Abstract (93) | Core Tip (77) | Full Article (HTML) (921) | Figures (1-3) (53) | Tables (1-2) (63) | Full Article (PDF)-2342K (247) | Full Article with Cover (PDF)-2663K (106) | Full Article (XML)-302K (22) | Audio-301K (23) | Peer-Review Report-227K (29) | Answering Reviewers-167K (31) | Received: 06/30/2025 | Revised: 08/05/2025 | Accepted: 11/06/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (2172) | Similar Articles (0) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Sedation and analgesia strategies in the neuro intensive care unit

Zachary I Merhavy, Tereque Raeburn, Gloria M Torres-Ayala, Melissa A McCulloch, Thomas C Varkey

World J Crit Care Med 14(4):111787. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.111787

Abstract (74) | Core Tip (82) | Full Article (HTML) (872) | Figures (1-4) (77) | Tables (1-1) (57) | Full Article (PDF)-6389K (205) | Full Article with Cover (PDF)-6710K (102) | Full Article (XML)-229K (32) | Audio-987K (35) | Peer-Review Report-408K (27) | Answering Reviewers-241K (23) | Received: 07/08/2025 | Revised: 07/23/2025 | Accepted: 09/12/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (2220) | Similar Articles (16) | Timeline of Article Publication (0) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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Minireviews

Sepsis and the diverse organ-gastrointestinal tract axis

Jia Dong James Wang, Enhui Suan, Sean Siwei Li, Vishal G Shelat

World J Crit Care Med 14(4):105547. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.105547

Abstract (98) | Core Tip (74) | Full Article (HTML) (587) | Figures (1-2) (70) | Full Article (PDF)-1547K (231) | Full Article with Cover (PDF)-1867K (64) | Full Article (XML)-146K (28) | Audio-2176K (34) | Peer-Review Report-207K (31) | Answering Reviewers-7K (25) | Received: 01/25/2025 | Revised: 04/16/2025 | Accepted: 06/03/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (1812) | Similar Articles (100) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Haemostasis and beyond: The expanding role of desmopressin in intensive care

Saketh Vinjamuri, Ekta Tiwari, Sahil Kataria, Deven Juneja

World J Crit Care Med 14(4):108370. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.108370

Abstract (75) | Core Tip (96) | Full Article (HTML) (2880) | Figures (1-2) (83) | Tables (1-5) (134) | Full Article (PDF)-1855K (680) | Full Article with Cover (PDF)-2169K (113) | Full Article (XML)-207K (30) | Audio-565K (10) | Peer-Review Report-245K (30) | Answering Reviewers-60K (36) | Received: 04/11/2025 | Revised: 05/23/2025 | Accepted: 08/05/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (4834) | Similar Articles (1) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Hydroelectrolytic syndromes in neuroanesthesia and neurocritical care

Felipe Mejia Herrera, Luca Marino, Federico Bilotta

World J Crit Care Med 14(4):108744. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.108744

Abstract (82) | Core Tip (77) | Full Article (HTML) (425) | Tables (1-5) (62) | Full Article (PDF)-457K (118) | Full Article with Cover (PDF)-776K (68) | Full Article (XML)-137K (40) | Audio-364K (26) | Peer-Review Report-257K (31) | Answering Reviewers-74K (32) | Received: 04/21/2025 | Revised: 05/26/2025 | Accepted: 09/01/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1467) | Similar Articles (24) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Management of acute liver failure-an updated literature review

Vignesh K Nagesh, Emelyn Martinez, Shruthi Badam, Jevon Lamar Harrison, Marina Basta, Vivek Joseph Varughese, Ghulam R Anwar, Vishal Deshpande, Deepa Francis, Damien Islek, Sai Priyanka Pulipaka, Ruchi Bhuju, Pratiksha Moliya, Bilal Niazi, Sameh Elias

World J Crit Care Med 14(4):108840. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.108840

Abstract (102) | Core Tip (122) | Full Article (HTML) (1220) | Figures (1-1) (56) | Tables (1-1) (75) | Full Article (PDF)-4147K (425) | Full Article with Cover (PDF)-4465K (37) | Full Article (XML)-191K (37) | Audio-409K (37) | Peer-Review Report-349K (36) | Answering Reviewers-127K (25) | Received: 04/23/2025 | Revised: 05/19/2025 | Accepted: 08/25/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (2835) | Similar Articles (78) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Intra-arterial catheters: An evidence-based review of device design, function and application

Julian Yaxley

World J Crit Care Med 14(4):109164. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.109164

Abstract (65) | Core Tip (68) | Full Article (HTML) (897) | Figures (1-1) (57) | Tables (1-3) (77) | Full Article (PDF)-690K (151) | Full Article with Cover (PDF)-1009K (27) | Full Article (XML)-197K (30) | Audio-367K (28) | Peer-Review Report-356K (27) | Answering Reviewers-114K (27) | Received: 04/30/2025 | Revised: 06/17/2025 | Accepted: 09/16/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1940) | Similar Articles (0) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Ivabradine in acute care: Revisiting the funny current in critical care context

Arun Mukesh, Ankur Sharma, Nikhil Kothari

World J Crit Care Med 14(4):111054. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.111054

Abstract (70) | Core Tip (73) | Full Article (HTML) (457) | Figures (1-2) (72) | Tables (1-2) (68) | Full Article (PDF)-1364K (97) | Full Article with Cover (PDF)-1685K (55) | Full Article (XML)-47K (29) | Audio-924K (9) | Peer-Review Report-197K (32) | Answering Reviewers-168K (22) | Received: 06/21/2025 | Revised: 07/08/2025 | Accepted: 10/10/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1733) | Similar Articles (4) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Case Control Study

Clinical and cost-effectiveness of noninvasive ventilation over invasive ventilation in acute respiratory failure: A single-center study from India

Kanwalpreet Sodhi, Harmanpreet Kaur, Tanupriya Sood, Ditya Ditya, Manender Kumar, Sartaaj Tuli, Anshul Singla, Ishrat Singla

World J Crit Care Med 14(4):108652. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.108652

Abstract (88) | Core Tip (71) | Full Article (HTML) (307) | Figures (1-1) (59) | Tables (1-4) (56) | Full Article (PDF)-502K (51) | Full Article with Cover (PDF)-823K (66) | Full Article (XML)-72K (27) | Audio-950K (10) | Peer-Review Report-223K (25) | Answering Reviewers-27K (29) | Received: 04/19/2025 | Revised: 05/28/2025 | Accepted: 08/12/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (1665) | Similar Articles (22) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Retrospective Cohort Study

Length of stay, duration of mechanical ventilation, mortality, and acute kidney injury in acute respiratory failure requiring endotracheal intubation

Panagiotis Papamichalis, Katerina G Oikonomou, Maria Xanthoudaki, Sophia K Papathanasiou, Antonios Papadogoulas, Apostolia Lemonia Skoura, Asimina Valsamaki, Dimitrios Plageras, Michail Papamichalis, Periklis Katsiafylloudis, Evangelia Papapostolou, Konstantinos Mantzarlis, Athanasios Koukoulis, Gkreta Mavrommati, Panagiotis Giannakos, Achilleas Chovas

World J Crit Care Med 14(4):103708. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.103708

Abstract (87) | Core Tip (71) | Full Article (HTML) (292) | Figures (1-1) (67) | Tables (1-7) (54) | Full Article (PDF)-2905K (41) | Full Article with Cover (PDF)-3226K (43) | Full Article (XML)-161K (29) | Audio-936K (9) | Peer-Review Report-345K (23) | Answering Reviewers-128K (48) | Received: 11/28/2024 | Revised: 04/28/2025 | Accepted: 07/07/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1534) | Similar Articles (232) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Predictive accuracy of 4C Mortality Score and Acute Physiology and Chronic Health Evaluation scores for mortality in COVID-19 patients admitted to intensive care unit

Kush Deshpande, Dushyant Tripathi

World J Crit Care Med 14(4):108907. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.108907

Abstract (73) | Core Tip (68) | Full Article (HTML) (225) | Figures (1-3) (60) | Tables (1-8) (52) | Full Article (PDF)-899K (41) | Full Article with Cover (PDF)-1220K (36) | Full Article (XML)-89K (28) | Audio-796K (7) | Peer-Review Report-218K (29) | Answering Reviewers-239K (25) | Received: 04/25/2025 | Revised: 06/02/2025 | Accepted: 08/29/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1487) | Similar Articles (862) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Acute kidney injury in critically ill patients with traumatic brain injury: A single-center retrospective cohort study

Bhushan Sudhakar Wankhade, Mohamed Hamed Ibrahim Ali El Kholi, Zeyad Faoor Alrais, Adel Elsaid Salem Elkhouly, Gopala Arun Kumar Naidu, Alim Akbar Patel, Mohamed Sameer, Mohammed Shahid Abbas, Nowar Nouralla Fadol Elbasier, Aala Fadlalla El Hadi

World J Crit Care Med 14(4):110079. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.110079

Abstract (74) | Core Tip (68) | Full Article (HTML) (365) | Figures (1-2) (56) | Tables (1-5) (56) | Full Article (PDF)-612K (66) | Full Article with Cover (PDF)-930K (63) | Full Article (XML)-117K (34) | Audio-365K (17) | Peer-Review Report-497K (34) | Answering Reviewers-91K (21) | Received: 05/28/2025 | Revised: 06/20/2025 | Accepted: 09/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (1778) | Similar Articles (96) | Timeline of Article Publication (4) | Authors Evaluation (10) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Retrospective Study

Retrospective evaluation of efficacy of CytoSorb^® therapy in septic shock patients in a tertiary care intensive care unit

Mayur S Shah, Vedika V Sharma, Syed J Patel, Abdul S Ansari

World J Crit Care Med 14(4):105600. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.105600

Abstract (73) | Core Tip (93) | Full Article (HTML) (357) | Figures (1-5) (68) | Tables (1-3) (54) | Full Article (PDF)-9852K (167) | Full Article with Cover (PDF)-10170K (93) | Full Article (XML)-133K (31) | Audio-2483K (12) | Peer-Review Report-264K (27) | Answering Reviewers-90K (29) | Supplementary Material-222K (28) | Received: 01/28/2025 | Revised: 05/08/2025 | Accepted: 08/06/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (1724) | Similar Articles (34) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Extracorporeal membrane oxygenation support in patients with difficult airway management: Case series of 13 patients

Mugahid Eltahir, Ibrahim Fawzy, Abdulsalam Saif Ibrahim, Ezzeddin A Ibrahim, Rashid Mazhar, Nabil Abd Elhamid Shallik, Ayman El-Menyar, Ahmed Labib Shehatta

World J Crit Care Med 14(4):106027. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.106027

Abstract (66) | Core Tip (74) | Full Article (HTML) (366) | Figures (1-5) (58) | Tables (1-1) (55) | Full Article (PDF)-57023K (93) | Full Article with Cover (PDF)-57346K (182) | Full Article (XML)-68K (29) | Audio-178K (10) | Peer-Review Report-208K (31) | Answering Reviewers-56K (28) | Received: 02/13/2025 | Revised: 04/09/2025 | Accepted: 05/26/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (2487) | Similar Articles (12) | Timeline of Article Publication (0) | Authors Evaluation (2) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Outcome predictors of systemic lupus erythematosus requiring admission to the intensive care unit

Anitha P Mampilly, Binila Chacko, John Mathew, Krupa George, Anna Paul, Sudha Jasmine, Samuel George, Karthik Gunasekaran, Rajnin Nanda, Vaanya Bansal, John V Peter

World J Crit Care Med 14(4):108689. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.108689

Abstract (71) | Core Tip (66) | Full Article (HTML) (328) | Tables (1-6) (77) | Full Article (PDF)-478K (69) | Full Article with Cover (PDF)-799K (53) | Full Article (XML)-130K (30) | Audio-384K (11) | Peer-Review Report-284K (26) | Answering Reviewers-65K (29) | Received: 04/21/2025 | Revised: 05/19/2025 | Accepted: 08/13/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1492) | Similar Articles (96) | Timeline of Article Publication (8) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Clinical Trials Study

Efficacy and safety of exosomes from Wharton’s Jelly-derived mesenchymal stem cells in traumatic brain injury

Serdar Kabatas, Erdinç Civelek, Eyüp Can Savrunlu, Necati Kaplan, Tunç Akkoc, Nurten Küçükçakır, Mehmet Bozkurt, Erdal Karaöz

World J Crit Care Med 14(4):103782. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.103782

Abstract (89) | Core Tip (104) | Full Article (HTML) (374) | Figures (1-5) (69) | Tables (1-6) (67) | Full Article (PDF)-1361K (85) | Full Article with Cover (PDF)-1682K (30) | Full Article (XML)-117K (32) | Audio-654K (24) | Peer-Review Report-276K (42) | Answering Reviewers-179K (39) | Received: 11/29/2024 | Revised: 04/01/2025 | Accepted: 06/07/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (1756) | Similar Articles (165) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Observational Study

Preventing diagnostic errors in critical care using millimeter-wave technology: A transformative approach to patient safety

Andreas G Siamarou

World J Crit Care Med 14(4):104703. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.104703

Abstract (67) | Core Tip (68) | Full Article (HTML) (310) | Figures (1-3) (64) | Tables (1-4) (59) | Full Article (PDF)-3799K (88) | Full Article with Cover (PDF)-4117K (83) | Full Article (XML)-101K (30) | Audio-1686K (7) | Peer-Review Report-261K (27) | Answering Reviewers-452K (29) | Received: 12/30/2024 | Revised: 04/24/2025 | Accepted: 08/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1479) | Similar Articles (69) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(1) | (0) | (0) | (0) | Open

Optic nerve sheath diameter trajectories and mortality in children with clinically relevant elevated intracranial pressure

Dat Minh-Tan Truong, Minh Hoang-Nhat Nguyen, Huy Quang Nguyen, Luan Thanh Vo, Thanh Tat Nguyen

World J Crit Care Med 14(4):110669. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.110669

Abstract (73) | Core Tip (76) | Full Article (HTML) (331) | Figures (1-3) (93) | Tables (1-5) (60) | Full Article (PDF)-1314K (60) | Full Article with Cover (PDF)-1634K (42) | Full Article (XML)-114K (24) | Audio-1399K (14) | Peer-Review Report-280K (28) | Answering Reviewers-483K (22) | Received: 06/11/2025 | Revised: 07/01/2025 | Accepted: 09/24/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (1559) | Similar Articles (151) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Critical care primary services are associated with reduced midazolam use in the intensive care unit

Konstantin G Nestoiter, Kristin Feick, Kristen Looney, Matthew Zaccheo, Yijin Wert, Christopher Franz

World J Crit Care Med 14(4):111260. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.111260

Abstract (64) | Core Tip (67) | Full Article (HTML) (329) | Figures (1-6) (59) | Tables (1-5) (62) | Full Article (PDF)-1053K (42) | Full Article with Cover (PDF)-1374K (137) | Full Article (XML)-71K (26) | Audio-253K (12) | Peer-Review Report-200K (30) | Answering Reviewers-405K (43) | Received: 06/26/2025 | Revised: 07/23/2025 | Accepted: 10/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1700) | Similar Articles (60) | Timeline of Article Publication (3) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Prospective Study

Effectiveness of a noise reduction intervention in the intensive care unit: A prospective bicenter study

Bernard Ong, Kay Choong See, Sunny Sunwoo Kim, Yie Hui Lau

World J Crit Care Med 14(4):106359. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.106359

Abstract (79) | Core Tip (74) | Full Article (HTML) (292) | Figures (1-3) (59) | Tables (1-2) (61) | Full Article (PDF)-1136K (42) | Full Article with Cover (PDF)-1457K (33) | Full Article (XML)-63K (26) | Audio-103K (13) | Peer-Review Report-3995K (34) | Answering Reviewers-88K (24) | Received: 02/24/2025 | Revised: 04/01/2025 | Accepted: 05/29/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1384) | Similar Articles (0) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Randomized Controlled Trial

Effect of music therapy on outcomes of critically ill patients

Sabiha Mukhtar, Mohd Mustahsin, Madhulika Dubey, Syed Ahmed Hussain Kazmi, Piyush Shishir

World J Crit Care Med 14(4):111059. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.111059

Abstract (92) | Core Tip (84) | Full Article (HTML) (416) | Figures (1-2) (60) | Tables (1-13) (66) | Full Article (PDF)-1358K (167) | Full Article with Cover (PDF)-1677K (35) | Full Article (XML)-122K (31) | Audio-377K (28) | Peer-Review Report-224K (27) | Answering Reviewers-56K (30) | Received: 06/21/2025 | Revised: 07/28/2025 | Accepted: 11/04/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (1968) | Similar Articles (14) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Basic Study

Reactive oxygen species elevations in human immune cell subsets during sepsis are mitigated by norepinephrine and N-acetylcysteine

Joby Thoppil, J David Farrar, Drashya Sharma, Shaun Kirby, Angela Mobley, Daniel Mark Courtney

World J Crit Care Med 14(4):108638. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.108638

Abstract (74) | Core Tip (79) | Full Article (HTML) (309) | Figures (1-4) (73) | Full Article (PDF)-2341K (55) | Full Article with Cover (PDF)-2662K (39) | Full Article (XML)-90K (29) | Audio-186K (11) | Peer-Review Report-475K (30) | Answering Reviewers-1378K (28) | Received: 04/18/2025 | Revised: 05/13/2025 | Accepted: 05/29/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (2109) | Similar Articles (141) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Systematic Reviews

Current and emerging therapeutic options for refractory septic shock: A systematic review

Flavio Eduardo Nacul, Murilo Borges Bezerra, Brenno Cardoso Gomes, Fábio Barlem Hohmann, Ricardo Esper Treml, Tulio Caldonazo, Arnaldo Alves da Silva, Rogerio H Passos, Neymar Elias de Oliveira, Grazielle Pangratz Bedretchuk, Joao Manoel Silva Jr

World J Crit Care Med 14(4):111164. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.111164

Abstract (61) | Core Tip (85) | Full Article (HTML) (631) | Figures (1-1) (63) | Tables (1-4) (69) | Full Article (PDF)-559K (135) | Full Article with Cover (PDF)-879K (61) | Full Article (XML)-164K (29) | Audio-327K (12) | Peer-Review Report-243K (23) | Answering Reviewers-35K (23) | Received: 07/06/2025 | Revised: 08/05/2025 | Accepted: 08/27/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1945) | Similar Articles (0) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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In-hospital vs out-of-hospital cardiac arrest in the Arab Asian countries: A contemporary review of the literature

Haya Alkuwari, Noora Al-Sulaiti, Wafaa Al-Mannai, Mohammad Asim, Hassan Al-Thani, Ayman El-Menyar

World J Crit Care Med 14(4):112368. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.112368

Abstract (78) | Core Tip (70) | Full Article (HTML) (290) | Figures (1-3) (74) | Tables (1-3) (59) | Full Article (PDF)-723K (140) | Full Article with Cover (PDF)-1044K (91) | Full Article (XML)-201K (25) | Audio-289K (11) | Peer-Review Report-195K (27) | Answering Reviewers-70K (23) | Received: 07/24/2025 | Revised: 07/30/2025 | Accepted: 10/29/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (1475) | Similar Articles (23) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Meta-Analysis

Safety and early mobilization in intensive care unit patients: An updated systematic review and meta-analysis of randomized controlled trials

Syed A Khan, Abdul Moeed, Tahreem Mari, Zehra Yousuf, Arthur Hanson, Yue Dong, Patrick Cornelius, Humayun Anjum, Iqbal Ratnani, Salim Surani

World J Crit Care Med 14(4):107396. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.107396

Abstract (87) | Core Tip (113) | Full Article (HTML) (1492) | Figures (1-2) (68) | Tables (1-2) (60) | Full Article (PDF)-1591K (385) | Full Article with Cover (PDF)-1911K (145) | Full Article (XML)-134K (30) | Audio-491K (98) | Peer-Review Report-183K (31) | Answering Reviewers-179K (29) | Supplementary Material-117K (27) | Received: 03/22/2025 | Revised: 04/17/2025 | Accepted: 05/27/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (4149) | Similar Articles (67) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Stroke metrics, safety, and outcomes of telemedicine-administered thrombolytics for acute ischemic stroke: A meta-analysis

Andrea Loggini, Amber Schwertman, Jonatan Hornik, Karam Dallow, Alejandro Hornik

World J Crit Care Med 14(4):107570. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.107570

Abstract (78) | Core Tip (68) | Full Article (HTML) (204) | Figures (1-2) (59) | Tables (1-2) (62) | Full Article (PDF)-1258K (131) | Full Article with Cover (PDF)-1580K (55) | Full Article (XML)-81K (30) | Audio-11K (18) | Peer-Review Report-182K (33) | Answering Reviewers-126K (20) | Supplementary Material-277K (28) | Received: 03/25/2025 | Revised: 04/11/2025 | Accepted: 05/27/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1490) | Similar Articles (694) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Palliative care in pulmonary hypertension: A systematic review and meta-analysis

Wajid Ali, Asad Ur Rab, Asim Shaikh, Gokhan Anil, Salim Surani, Munish Sharma

World J Crit Care Med 14(4):110597. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.110597

Abstract (71) | Core Tip (73) | Full Article (HTML) (290) | Figures (1-2) (61) | Tables (1-4) (67) | Full Article (PDF)-891K (45) | Full Article with Cover (PDF)-1211K (27) | Full Article (XML)-104K (24) | Audio-719K (13) | Peer-Review Report-258K (19) | Answering Reviewers-299K (25) | Received: 06/09/2025 | Revised: 07/23/2025 | Accepted: 10/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1377) | Similar Articles (12) | Timeline of Article Publication (0) | Authors Evaluation (2) | Article Quality Tracking (0) | Cite |

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Case Report

Vasopressin role in hypertrophic obstructive cardiomyopathy post-cardiac surgery: A case report

Dimitrios Elaiopoulos, Fotios Dimitriadis, Eleni Tzatzaki, Maria Chronaki, Konstantina Kolonia, Michalis Antonopoulos, Giorgos Konstantinou, Nektarios Kogerakis, Stavros Dimopoulos

World J Crit Care Med 14(4):106485. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.106485

Abstract (74) | Core Tip (82) | Full Article (HTML) (351) | Figures (1-4) (59) | Full Article (PDF)-12992K (210) | Full Article with Cover (PDF)-13313K (53) | Full Article (XML)-54K (37) | Audio-1071K (13) | Videos (1-2) (8) | Peer-Review Report-314K (25) | Answering Reviewers-339K (23) | Received: 03/13/2025 | Revised: 05/05/2025 | Accepted: 07/23/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (2404) | Similar Articles (4575) | Timeline of Article Publication (0) | Authors Evaluation (3) | Article Quality Tracking (0) | Cite |

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Thrombotic storm presenting with synchronous myocardial infarction, stroke and bowel ischaemia: A case report

Wen-Jian Chan, Timothy Xin Zhong Tan, R Ponampalam, Arjun Thompson

World J Crit Care Med 14(4):109786. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.109786

Abstract (74) | Core Tip (78) | Full Article (HTML) (253) | Figures (1-8) (75) | Full Article (PDF)-7274K (47) | Full Article with Cover (PDF)-7596K (39) | Full Article (XML)-60K (28) | Audio-1212K (12) | Peer-Review Report-203K (25) | Answering Reviewers-118K (26) | Received: 05/21/2025 | Revised: 06/17/2025 | Accepted: 08/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1353) | Similar Articles (4615) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Letter to the Editor

Paradox of protection: Re-examining cannabis use disorder in sepsis outcomes among cancer patients

Wu-Si Qiu, Hao-Dong Chen, Wen-Jie Yang, Ming-Min Chen

World J Crit Care Med 14(4):106085. Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.106085

Abstract (74) | Core Tip (68) | Full Article (HTML) (219) | Full Article (PDF)-369K (43) | Full Article with Cover (PDF)-690K (46) | Full Article (XML)-60K (25) | Audio-16696K (6) | Peer-Review Report-213K (23) | Answering Reviewers-349K (18) | Received: 02/15/2025 | Revised: 04/16/2025 | Accepted: 06/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1164) | Similar Articles (331) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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