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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Crit Care Med. Dec 9, 2025; 14(4): 110079
Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.110079
Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.110079
Acute kidney injury in critically ill patients with traumatic brain injury: A single-center retrospective cohort study
Bhushan Sudhakar Wankhade, Mohamed Hamed Ibrahim Ali El Kholi, Zeyad Faoor Alrais, Adel Elsaid Salem Elkhouly, Gopala Arun Kumar Naidu, Alim Akbar Patel, Mohamed Sameer, Mohammed Shahid Abbas, Nowar Nouralla Fadol Elbasier, Aala Fadlalla El Hadi, Surgical Intensive Care, Rashid Hospital, Dubai 7272, United Arab Emirates
Bhushan Sudhakar Wankhade, Mohamed Hamed Ibrahim Ali El Kholi, Zeyad Faoor Alrais, College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai 505055, United Arab Emirates
Author contributions: Wankhade BS and El Kholi MHIA planned the methodology; Wankhade BS, El Kholi MHIA, and Alrais ZF Elkhouly AES conducted the conceptualization and project administration; Naidu GAK, Patel AA, Sameer M, Abbas MS, Elbasier NNF, and El Hadi AF performed the data curation and formal analyses; Wankhade BS, El Kholi MHIA, Alrais ZF, Elkhouly AES, Naidu GAK, Patel AA, Sameer M, Abbas MS, Elbasier NNF, and El Hadi AF wrote the original draft, and reviewed and edited the manuscript; All authors read and approved the final version of the manuscript to be published.
Institutional review board statement: This study was approved by the institutional review board of Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai with approval number MBRU IRB-2023-323, dated 25 January 2024.
Informed consent statement: The use of retrospective de-identified data in the study resulted in the waiver of written informed consent from patients. The consent waiver was approved by the institutional review board.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: Deidentified data and study materials are available upon reasonable request from the corresponding author at bhushansudhakar2018@gmail.com
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bhushan Sudhakar Wankhade, MD, Surgical Intensive Care, Rashid Hospital, Oud Metha, Dubai 7272, United Arab Emirates. bhushansudhakar2018@gmail.com
Received: May 29, 2025
Revised: June 20, 2025
Accepted: September 17, 2025
Published online: December 9, 2025
Processing time: 184 Days and 3 Hours
Revised: June 20, 2025
Accepted: September 17, 2025
Published online: December 9, 2025
Processing time: 184 Days and 3 Hours
Core Tip
Core Tip: After traumatic brain injury (TBI), patients are prone to develop non-neurological complications. Intensivists play a vital role in managing patients with TBI and preventing non-neurological complications. Among various non-neurological complications after TBI, acute kidney injury (AKI) is not uncommon and can negatively affect the patient's outcome. The incidence, risk factors, and predictors of AKI events in patients with TBI are further revealed by this study. In general, the severity of injury is the main determinant of both the development of AKI and the patient's outcome after TBI.
