Giving urine biochemistry a second chance in acute kidney injury monitoring

doi:10.5492/wjccm.v14.i4.109194

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Dec 9, 2025 (publication date) through Dec 9, 2025

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World Journal of Critical Care Medicine

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2220-3141

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Crit Care Med. Dec 9, 2025; 14(4): 109194
Published online Dec 9, 2025. doi: 10.5492/wjccm.v14.i4.109194

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Figure 1 Schematic representation of creatinine production, distribution, and excretion from the body and the information retrieved from urine biochemical parameters accordingly. CrU: Urinary creatinine concentration; KU: Urinary potassium concentration; sCr: Serum creatinine; UO: Urinary output.

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Figure 2 Distinct scenarios and proper interpretations of urinary potassium and urinary creatinine as well as their ratio, considering normal serum potassium and creatinine. AKI: Acute kidney injury; CrU: Urinary creatinine concentration; KU: Urinary potassium concentration; sCr: Serum creatinine; UO: Urine output.

Citation: Maciel AT. Giving urine biochemistry a second chance in acute kidney injury monitoring. World J Crit Care Med 2025; 14(4): 109194
URL: https://www.wjgnet.com/2220-3141/full/v14/i4/109194.htm
DOI: https://dx.doi.org/10.5492/wjccm.v14.i4.109194