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Contents Volume 17 Issue 12 December 15, 2025

Editorial

miR-136: A biomarker in the inflammation-cancer transformation of gastric cancer

Hao Lyu, Jia-Si Chen, Jing-Feng Tang, Ce-Fan Zhou

World J Gastrointest Oncol 17(12):114173. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.114173

Abstract (58) | Core Tip (65) | Full Article (HTML) (256) | Full Article (PDF)-395K (57) | Full Article with Cover (PDF)-796K (128) | Full Article (XML)-100K (25) | Audio-194K (7) | Peer-Review Report-245K (20) | Answering Reviewers-44K (20) | Received: 09/12/2025 | Revised: 10/11/2025 | Accepted: 10/29/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1329) | Similar Articles (1429) | Timeline of Article Publication (0) | Authors Evaluation (1) | Cite |

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Cost vs clinical utility on application of large language models in clinical practice: A double-edged sword

Sunny Chi Lik Au

World J Gastrointest Oncol 17(12):114341. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.114341

Abstract (72) | Core Tip (62) | Full Article (HTML) (220) | Tables (1-1) (53) | Full Article (PDF)-377K (62) | Full Article with Cover (PDF)-779K (90) | Full Article (XML)-47K (23) | Audio-335K (6) | Peer-Review Report-202K (18) | Answering Reviewers-153K (24) | Received: 09/16/2025 | Revised: 09/26/2025 | Accepted: 10/27/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1171) | Similar Articles (13) | Timeline of Article Publication (0) | Cite |

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Review

Molecular mechanism of non-coding RNAs-mediated radiosensitivity regulation in colorectal cancer

Xiao Li, Xiu-Xia Hao, Rui-Qing Zhu, Hong-Wei Zhou

World J Gastrointest Oncol 17(12):113636. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.113636

Abstract (68) | Core Tip (61) | Full Article (HTML) (196) | Tables (1-3) (59) | Full Article (PDF)-523K (43) | Full Article with Cover (PDF)-924K (36) | Full Article (XML)-222K (33) | Audio-620K (4) | Peer-Review Report-223K (24) | Answering Reviewers-113K (24) | Received: 08/29/2025 | Revised: 09/25/2025 | Accepted: 10/28/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1572) | Similar Articles (1150) | Timeline of Article Publication (3) | Authors Evaluation (1) | Cite |

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Minireviews

Interlaced roles of mitochondrial DNA in colorectal cancer: Liquid-biopsy biomarkers, nuclear mtDNA-driven genomic instability, and mito-encoded micro peptide signaling

Thai-Hau Koo, Xue-Bin Leong, Yi-Lin Lee, Firdaus Hayati, Andee Dzulkarnaen Zakaria

World J Gastrointest Oncol 17(12):112753. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.112753

Abstract (61) | Core Tip (55) | Full Article (HTML) (382) | Tables (1-1) (62) | Full Article (PDF)-541K (73) | Full Article with Cover (PDF)-941K (50) | Full Article (XML)-164K (22) | Audio-685K (7) | Peer-Review Report-238K (21) | Answering Reviewers-135K (19) | Received: 08/04/2025 | Revised: 09/28/2025 | Accepted: 11/12/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1736) | Similar Articles (0) | Timeline of Article Publication (1) | Authors Evaluation (1) | Cite |

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Bidirectional relationship between depression and the risk and prognosis of gastric cancer

Zhe Chen, Ting-Jie Gong, Lu Zhao

World J Gastrointest Oncol 17(12):113272. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.113272

Abstract (66) | Core Tip (75) | Full Article (HTML) (352) | Figures (1-1) (53) | Full Article (PDF)-916K (61) | Full Article with Cover (PDF)-1317K (47) | Full Article (XML)-99K (25) | Audio-1141K (8) | Peer-Review Report-222K (30) | Answering Reviewers-165K (29) | Received: 08/26/2025 | Revised: 09/26/2025 | Accepted: 11/07/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1376) | Similar Articles (1565) | Timeline of Article Publication (2) | Reader Comments (1) | Cite |

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Retrospective Cohort Study

Clinical significance of citrullinated glial fibrillary acidic protein in predicting outcomes in hepatocellular carcinoma

Yoon Ah Cho, Dong Woo Shin, Mo-Jong Kim, Ji-Won Park, Ji-Young Choe, Jung-Woo Lee, Sung-Hoon Moon, Akihito Ishigami, Eun Kyoung Choi, Sung-Eun Kim

World J Gastrointest Oncol 17(12):110877. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.110877

Abstract (75) | Core Tip (56) | Full Article (HTML) (226) | Figures (1-2) (53) | Tables (1-3) (52) | Full Article (PDF)-8055K (47) | Full Article with Cover (PDF)-8455K (55) | Full Article (XML)-121K (31) | Audio-1097K (5) | Peer-Review Report-292K (35) | Answering Reviewers-495K (17) | Received: 06/20/2025 | Revised: 07/29/2025 | Accepted: 11/12/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (1425) | Similar Articles (1882) | Timeline of Article Publication (3) | Cite |

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Application of multimodal fusion technology in early recurrence prediction and pathological analysis of hepatocellular carcinoma

Li-Hong Huang, Yi-Jing Fang, Xiao-Jun Zheng, Ce Huang, Chang-Lu Li, Bin Yu, Meng-Jie Huang, Shi-Ji Qin, De-You Huang, De-Wei Lu

World J Gastrointest Oncol 17(12):114037. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.114037

Abstract (66) | Core Tip (62) | Full Article (HTML) (377) | Figures (1-6) (58) | Tables (1-5) (47) | Full Article (PDF)-4334K (78) | Full Article with Cover (PDF)-4734K (65) | Full Article (XML)-126K (27) | Audio-1259K (5) | Peer-Review Report-272K (25) | Answering Reviewers-182K (44) | Received: 09/09/2025 | Revised: 10/02/2025 | Accepted: 11/06/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (2429) | Similar Articles (1890) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Retrospective Study

Early and late-onset colorectal cancer in African Americans during COVID-19

Lakshmi G Chirumamilla, Hassan Brim, Suryanarayana R Challa, Gholamreza Oskrochi, Mrinalini Deverapalli, Rumaisa Rashid, Mudasir Rashid, Farshad Aduli, Angesom Kibreab, Adeyinka Laiyemo, Zaki A Sherif, Nader Shayegh, Babak Shokrani, Rabia Zafar, John M Carethers, Hassan Ashktorab

World J Gastrointest Oncol 17(12):105800. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.105800

Abstract (86) | Core Tip (87) | Full Article (HTML) (268) | Figures (1-1) (47) | Tables (1-2) (48) | Full Article (PDF)-586K (45) | Full Article with Cover (PDF)-987K (41) | Full Article (XML)-110K (34) | Audio-453K (5) | Peer-Review Report-300K (25) | Answering Reviewers-94K (42) | Received: 02/11/2025 | Revised: 05/16/2025 | Accepted: 11/07/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1631) | Similar Articles (1870) | Timeline of Article Publication (3) | Cite |

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Investigating radiotherapy’s impact on intestinal perforation risk in gastrointestinal tumor patients treated with bevacizumab

Wei-Mei He, Wen-Si Li

World J Gastrointest Oncol 17(12):110621. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.110621

Abstract (59) | Core Tip (77) | Full Article (HTML) (297) | Tables (1-4) (56) | Full Article (PDF)-450K (74) | Full Article with Cover (PDF)-849K (58) | Full Article (XML)-93K (25) | Audio-2156K (12) | Peer-Review Report-355K (25) | Answering Reviewers-160K (29) | Received: 07/01/2025 | Revised: 08/07/2025 | Accepted: 10/15/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (1624) | Similar Articles (126) | Timeline of Article Publication (0) | Cite |

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Exploring the improvement effect of intestinal network monitoring system on intestinal preparation quality of colonoscopy

Mei-Juan Xi, Yan-Ping Gong, Jian Tao, Fang Li, Min-Yi Xu, Xing Gu, Han Bao, Sheng Jiang, Bing Xu

World J Gastrointest Oncol 17(12):111101. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.111101

Abstract (97) | Core Tip (63) | Full Article (HTML) (256) | Tables (1-6) (59) | Full Article (PDF)-427K (66) | Full Article with Cover (PDF)-826K (52) | Full Article (XML)-89K (26) | Audio-349K (8) | Peer-Review Report-241K (21) | Answering Reviewers-48K (25) | Received: 06/27/2025 | Revised: 08/01/2025 | Accepted: 11/12/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1406) | Similar Articles (225) | Timeline of Article Publication (0) | Article Quality Tracking (1) | Cite |

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Preliminary exploration of programmed death 1 inhibitor combined with fruquintinib and docetaxel for advanced colorectal cancer

Xian-Yang Meng, Yu-Mei Cai, Ning-Ning Sun, Wen-Hua Zhang, Rui-Xue Cui, Long Zhang, Cheng-Cheng Zheng, Zhen Sun, Wei-Xuan Luo, Feng-Wei Wang

World J Gastrointest Oncol 17(12):112548. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.112548

Abstract (69) | Core Tip (68) | Full Article (HTML) (281) | Figures (1-2) (55) | Tables (1-4) (57) | Full Article (PDF)-591K (64) | Full Article with Cover (PDF)-992K (38) | Full Article (XML)-101K (25) | Audio-878K (7) | Peer-Review Report-240K (20) | Answering Reviewers-105K (23) | Received: 08/01/2025 | Revised: 08/27/2025 | Accepted: 11/03/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1388) | Similar Articles (29) | Timeline of Article Publication (0) | Authors Evaluation (1) | Cite |

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Clinical characteristics of colorectal polyps in patients with non-alcoholic fatty liver disease in high altitude areas

Chun-Yan Wang, Lin Ma, Ying Zhao, Xiao-Jiang Zhang, Shuang Li, Yong-Gang Liu, Hai-Ming Guo, Jun-Guo Qi, Jian-Quan Wang, Wei-Xin Ye, Jian-Zhou Li, Tao Zhang

World J Gastrointest Oncol 17(12):112761. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.112761

Abstract (65) | Core Tip (68) | Full Article (HTML) (207) | Figures (1-2) (53) | Tables (1-8) (49) | Full Article (PDF)-1006K (51) | Full Article with Cover (PDF)-1406K (54) | Full Article (XML)-112K (34) | Audio-871K (7) | Peer-Review Report-257K (18) | Answering Reviewers-72K (23) | Received: 08/05/2025 | Revised: 09/14/2025 | Accepted: 11/10/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1609) | Similar Articles (246) | Timeline of Article Publication (2) | Authors Evaluation (1) | Cite |

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Machine learning survival prediction in esophageal cancer using radiomics and body composition from pretreatment and follow-up T12-level computed tomography

Ming-Cheng Liu, Yung-Yin Cheng, Shao-Chieh Lin, Chih-Hung Lin, Cheng-Yen Chuang, Wen-Hsien Chen, Chun-Han Liao, Chia-Hong Hsieh, Mei-Fang Hsieh, Yi-Jui Liu

World J Gastrointest Oncol 17(12):112873. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.112873

Abstract (67) | Core Tip (59) | Full Article (HTML) (338) | Figures (1-7) (61) | Tables (1-7) (54) | Full Article (PDF)-5660K (87) | Full Article with Cover (PDF)-6061K (77) | Full Article (XML)-167K (23) | Audio-505K (29) | Peer-Review Report-198K (21) | Answering Reviewers-365K (46) | Supplementary Material-369K (21) | Received: 08/08/2025 | Revised: 09/28/2025 | Accepted: 10/28/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1696) | Similar Articles (377) | Timeline of Article Publication (0) | Article Quality Tracking (1) | Cite |

(0) | (0) | (0) | (0) | Open

Pancreatic neuroendocrine microtumors in the elderly: A retrospective study using cadaveric pancreatic tissue

Ting Yang, Ke Ren, Xiang-Quan Chen, Taku Toriumi, Yutaro Natsuyama, Jun Li, Aoi Sukeda, Toshitaka Nagao, Shuang-Qin Yi

World J Gastrointest Oncol 17(12):113198. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.113198

Abstract (64) | Core Tip (69) | Full Article (HTML) (232) | Figures (1-3) (55) | Tables (1-1) (49) | Full Article (PDF)-38548K (51) | Full Article with Cover (PDF)-38948K (52) | Full Article (XML)-95K (28) | Audio-811K (7) | Peer-Review Report-264K (22) | Answering Reviewers-344K (53) | Supplementary Material-230K (29) | Received: 08/19/2025 | Revised: 09/18/2025 | Accepted: 10/30/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1631) | Similar Articles (0) | Timeline of Article Publication (0) | Authors Evaluation (1) | Cite |

(0) | (0) | (0) | (0) | Open

Safety and efficacy of cryoablation in treating locally advanced pancreatic cancer

Li-Min Kang, Xiao-Long He, Li Lang, A-Yong Wang, Xian Wang, Yu-Hao Liu, Ying-Hong Zhao, Lei Xu, Fa-Kun Yu, Fu-Wei Zhang

World J Gastrointest Oncol 17(12):113387. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.113387

Abstract (77) | Core Tip (71) | Full Article (HTML) (412) | Figures (1-3) (56) | Tables (1-5) (57) | Full Article (PDF)-4986K (96) | Full Article with Cover (PDF)-5386K (61) | Full Article (XML)-98K (26) | Audio-1229K (20) | Peer-Review Report-200K (20) | Answering Reviewers-132K (20) | Received: 08/23/2025 | Revised: 09/28/2025 | Accepted: 10/31/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1896) | Similar Articles (458) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

(0) | (0) | (0) | (0) | Open

Clinical characteristics and prognostic analysis of three hundred and nineteen cases of primary gastrointestinal diffuse large B-cell lymphoma

Jia-Jia Ma, Huan Zhang, Cui-Cui Wang, Wen-Li Ji, Ying Zhao, Xin-Xia Li

World J Gastrointest Oncol 17(12):113661. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.113661

Abstract (75) | Core Tip (63) | Full Article (HTML) (228) | Figures (1-6) (52) | Tables (1-3) (50) | Full Article (PDF)-15819K (48) | Full Article with Cover (PDF)-16220K (47) | Full Article (XML)-103K (26) | Audio-1503K (6) | Peer-Review Report-307K (23) | Answering Reviewers-156K (26) | Received: 08/30/2025 | Revised: 09/18/2025 | Accepted: 11/05/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (2066) | Similar Articles (25) | Timeline of Article Publication (0) | Cite |

(0) | (0) | (0) | (0) | Open

Lymphocyte to C-reactive protein ratio as a novel inflammatory biomarker: Validation and clinical relevance as an independent prognostic factor in cholangiocarcinoma

Fan Xiao, De-Hua Zhou, Guo-Wei Liu, Chao-Wei Lin, Zi-You Wu, Hua Yu, Wei Gong, Wei-Feng Tan

World J Gastrointest Oncol 17(12):113853. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.113853

Abstract (58) | Core Tip (59) | Full Article (HTML) (229) | Figures (1-3) (48) | Tables (1-4) (51) | Full Article (PDF)-813K (47) | Full Article with Cover (PDF)-1213K (31) | Full Article (XML)-145K (19) | Audio-1326K (7) | Peer-Review Report-316K (25) | Answering Reviewers-163K (23) | Received: 09/04/2025 | Revised: 09/28/2025 | Accepted: 11/03/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1460) | Similar Articles (171) | Timeline of Article Publication (0) | Cite |

(0) | (0) | (0) | (0) | Open

Neutrophil-albumin ratio and multi-phase computed tomography for lymph node metastasis in pancreatic cancer

Huan Wang, Tian-Yu Fu, Fang Zhang, Fei-Chao Kang, Zhong-Wei Sun

World J Gastrointest Oncol 17(12):113879. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.113879

Abstract (77) | Core Tip (58) | Full Article (HTML) (259) | Figures (1-1) (48) | Tables (1-4) (53) | Full Article (PDF)-585K (63) | Full Article with Cover (PDF)-986K (71) | Full Article (XML)-101K (25) | Audio-1168K (5) | Peer-Review Report-251K (24) | Answering Reviewers-193K (35) | Received: 09/09/2025 | Revised: 10/11/2025 | Accepted: 11/06/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1624) | Similar Articles (505) | Timeline of Article Publication (0) | Cite |

(0) | (0) | (0) | (0) | Open

Prognostic significance of preoperative C-reactive protein-triglyceride-glucose index in long-term outcomes after radical gastrectomy for gastric cancer

Qiu-Lin Hao, Zhi-Yuan Yao, Yu-Meng Shen, Zheng-Yu Li, Hao-Chun Gao, Xiao-Yu Hong, Geng-Chen Li, Chao Gao

World J Gastrointest Oncol 17(12):113976. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.113976

Abstract (71) | Core Tip (68) | Full Article (HTML) (404) | Figures (1-5) (58) | Tables (1-4) (55) | Full Article (PDF)-1614K (140) | Full Article with Cover (PDF)-2014K (59) | Full Article (XML)-137K (25) | Audio-2633K (15) | Peer-Review Report-189K (25) | Answering Reviewers-105K (34) | Received: 09/08/2025 | Revised: 09/26/2025 | Accepted: 11/06/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1894) | Similar Articles (1307) | Timeline of Article Publication (6) | Authors Evaluation (4) | Cite |

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Basic Study

Transient receptor potential melastatin 6 and transient receptor potential melastatin 6/7 antagonists suppress colon adenocarcinoma HT-29 cells

Nattida Kampuang, Siriporn Chamniansawat, Pawin Pongkorpsakol, Supisara Treveeravoot, Narongrit Thongon

World J Gastrointest Oncol 17(12):110736. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.110736

Abstract (78) | Core Tip (65) | Full Article (HTML) (274) | Figures (1-7) (57) | Tables (1-3) (55) | Full Article (PDF)-19659K (68) | Full Article with Cover (PDF)-20059K (69) | Full Article (XML)-155K (27) | Audio-263K (12) | Peer-Review Report-334K (31) | Answering Reviewers-145K (34) | Received: 06/13/2025 | Revised: 07/08/2025 | Accepted: 10/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (1652) | Similar Articles (0) | Timeline of Article Publication (3) | Cite |

(0) | (0) | (0) | (0) | Open

Involvement of bile acids in cholangiocarcinoma progression via the Hippo-yes-associated protein signaling pathway

Jun Hu, Gan Zhang, Shuo Yang, Xian-Feng Shen, Meng Zhou, Lin-Sheng Huang, Hao-Ming Lan

World J Gastrointest Oncol 17(12):112366. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.112366

Abstract (68) | Core Tip (65) | Full Article (HTML) (258) | Figures (1-6) (56) | Tables (1-1) (54) | Full Article (PDF)-9785K (74) | Full Article with Cover (PDF)-10186K (43) | Full Article (XML)-109K (21) | Audio-440K (10) | Peer-Review Report-253K (23) | Answering Reviewers-211K (27) | Received: 07/24/2025 | Revised: 08/29/2025 | Accepted: 10/29/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (2242) | Similar Articles (194) | Timeline of Article Publication (1) | Cite |

(0) | (0) | (0) | (0) | Open

Optimized digital polymerase chain reaction enables detection of telomerase reverse transcriptase C228T mutation for prognostic assessment in hepatocellular carcinoma

Zulihumaer Aizimuaji, Nan Hu, Hai-Yang Li, Xi-Jun Wang, Sheng Ma, Ya-Ru Wang, Rui-Qi Zheng, Zhuo Li, Huan Zhao, Wei-Qi Rong, Ting Xiao

World J Gastrointest Oncol 17(12):113289. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.113289

Abstract (67) | Core Tip (67) | Full Article (HTML) (254) | Figures (1-8) (62) | Tables (1-2) (65) | Full Article (PDF)-5567K (39) | Full Article with Cover (PDF)-5968K (59) | Full Article (XML)-163K (27) | Audio-530K (12) | Peer-Review Report-196K (24) | Answering Reviewers-72K (22) | Supplementary Material-657K (28) | Received: 08/20/2025 | Revised: 09/30/2025 | Accepted: 10/29/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (1632) | Similar Articles (1939) | Timeline of Article Publication (2) | Cite |

(0) | (0) | (0) | (0) | Open

Exosomal miR-191 promotes colorectal cancer progression by inducing M2 macrophage polarization and inhibiting ferroptosis

Qing-Yun Zhao, Shou-Jiang Wei

World J Gastrointest Oncol 17(12):113524. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.113524

Abstract (57) | Core Tip (58) | Full Article (HTML) (288) | Figures (1-6) (48) | Full Article (PDF)-11352K (137) | Full Article with Cover (PDF)-11752K (21) | Full Article (XML)-118K (25) | Audio-267K (32) | Peer-Review Report-213K (24) | Answering Reviewers-245K (23) | Supplementary Material-118K (19) | Received: 08/27/2025 | Revised: 09/17/2025 | Accepted: 11/06/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (1861) | Similar Articles (1190) | Timeline of Article Publication (1) | Cite |

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Systematic Reviews

Tumor-resident microorganisms as clinical biomarkers in primary liver cancer: A systematic review of current evidence

Shuai Song, Li-Shan Xu, Lin-Qing Wang, Xiu Zhou, Xin Jiang, Chang-Ping Li

World J Gastrointest Oncol 17(12):112936. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.112936

Abstract (73) | Core Tip (68) | Full Article (HTML) (236) | Figures (1-3) (72) | Tables (1-2) (50) | Full Article (PDF)-3404K (327) | Full Article with Cover (PDF)-3799K (110) | Full Article (XML)-324K (30) | Audio-331K (12) | Peer-Review Report-245K (24) | Answering Reviewers-151K (44) | Received: 08/09/2025 | Revised: 09/14/2025 | Accepted: 10/31/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1780) | Similar Articles (323) | Timeline of Article Publication (0) | Authors Evaluation (1) | Cite |

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Meta-Analysis

Cancer-associated fibroblasts, clinicopathological characteristics and prognosis of liver cancer: A systematic review and meta-analysis based on real-world research

Yu-Hao Wei, Wen-Jing Jiang, Shi-Qian Wang, Yu-Long Cai, Xue-Lei Ma

World J Gastrointest Oncol 17(12):110395. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.110395

Abstract (64) | Core Tip (75) | Full Article (HTML) (241) | Figures (1-4) (51) | Tables (1-2) (52) | Full Article (PDF)-3805K (74) | Full Article with Cover (PDF)-4206K (52) | Full Article (XML)-126K (25) | Audio-554K (9) | Peer-Review Report-315K (27) | Answering Reviewers-119K (34) | Supplementary Material-227K (29) | Received: 06/06/2025 | Revised: 07/22/2025 | Accepted: 10/23/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1618) | Similar Articles (1073) | Timeline of Article Publication (1) | Article Quality Tracking (1) | Cite |

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Case Report

Long-term survival after treatment of gastric cancer with S-1 plus oxaliplatin regimen and sintilimab: A case report

Jun Pan, Ping Li, Yu-He Zhou, Ting-Ting Pan, Yi-Tian Chen, Xiao-Yuan Chu

World J Gastrointest Oncol 17(12):112853. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.112853

Abstract (68) | Core Tip (65) | Full Article (HTML) (243) | Figures (1-4) (51) | Full Article (PDF)-7830K (73) | Full Article with Cover (PDF)-8231K (38) | Full Article (XML)-78K (20) | Audio-891K (5) | Peer-Review Report-198K (20) | Answering Reviewers-147K (20) | Received: 08/07/2025 | Revised: 09/05/2025 | Accepted: 10/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1225) | Similar Articles (4568) | Timeline of Article Publication (2) | Authors Evaluation (1) | Cite |

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Tumor calcification and sustained complete response after chemoembolization in hepatocellular carcinoma: Two case reports and review of literature

Sultan R Alharbi

World J Gastrointest Oncol 17(12):113341. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.113341

Abstract (59) | Core Tip (63) | Full Article (HTML) (236) | Figures (1-12) (56) | Full Article (PDF)-11627K (54) | Full Article with Cover (PDF)-12027K (44) | Full Article (XML)-111K (25) | Audio-2415K (5) | Peer-Review Report-259K (25) | Answering Reviewers-128K (29) | Received: 08/21/2025 | Revised: 09/22/2025 | Accepted: 10/13/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1283) | Similar Articles (6395) | Timeline of Article Publication (0) | Authors Evaluation (1) | Cite |

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Advanced gastric small cell carcinoma with immunotherapy-based treatment: A case report

Xiao-Long Zhang, Jing-Yan Zhang, Ling Xie, Hui Li, Li Wang

World J Gastrointest Oncol 17(12):114390. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.114390

Abstract (65) | Core Tip (56) | Full Article (HTML) (224) | Figures (1-4) (47) | Full Article (PDF)-10601K (63) | Full Article with Cover (PDF)-11003K (43) | Full Article (XML)-61K (25) | Audio-847K (4) | Peer-Review Report-177K (27) | Answering Reviewers-96K (28) | Received: 09/19/2025 | Revised: 10/23/2025 | Accepted: 11/13/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1408) | Similar Articles (4743) | Timeline of Article Publication (5) | Authors Evaluation (1) | Cite |

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Letter to the Editor

Novel insights into SLC16A8 in colorectal cancer

Jing-Yuan Li, Guang Ji, Yan-Qi Dang

World J Gastrointest Oncol 17(12):112894. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.112894

Abstract (67) | Core Tip (66) | Full Article (HTML) (153) | Full Article (PDF)-345K (63) | Full Article with Cover (PDF)-748K (41) | Full Article (XML)-37K (23) | Audio-142K (5) | Peer-Review Report-240K (20) | Answering Reviewers-223K (20) | Received: 08/08/2025 | Revised: 09/12/2025 | Accepted: 10/23/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1224) | Similar Articles (1460) | Timeline of Article Publication (0) | Cite |

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Combining irreversible electroporation and immunotherapy for hepatocellular carcinoma: Reflections and directions for advancement

Arunkumar Krishnan, Diptasree Mukherjee

World J Gastrointest Oncol 17(12):113598. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.113598

Abstract (65) | Core Tip (77) | Full Article (HTML) (188) | Full Article (PDF)-349K (48) | Full Article with Cover (PDF)-752K (49) | Full Article (XML)-22K (26) | Audio-210K (5) | Peer-Review Report-218K (22) | Answering Reviewers-83K (23) | Received: 08/28/2025 | Revised: 09/17/2025 | Accepted: 10/22/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1062) | Similar Articles (1892) | Timeline of Article Publication (0) | Cite |

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Beyond the blank page: Frequentist and Bayesian perspectives on risk prediction algorithms

Francisco Tustumi, Felipe Antonio Boff Maegawa, Pedro Luiz Serrano Uson Junior

World J Gastrointest Oncol 17(12):113988. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.113988

Abstract (65) | Core Tip (62) | Full Article (HTML) (190) | Figures (1-2) (48) | Full Article (PDF)-773K (39) | Full Article with Cover (PDF)-1175K (53) | Full Article (XML)-36K (26) | Audio-535K (6) | Peer-Review Report-236K (22) | Answering Reviewers-87K (25) | Received: 09/08/2025 | Revised: 10/15/2025 | Accepted: 11/03/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1049) | Similar Articles (33) | Timeline of Article Publication (0) | Cite |

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Prognosis of intensive care unit patients with colorectal cancer

Yu-Ting Liao, Wen-Liang Zhu

World J Gastrointest Oncol 17(12):114109. Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.114109

Abstract (65) | Core Tip (61) | Full Article (HTML) (202) | Full Article (PDF)-377K (72) | Full Article with Cover (PDF)-776K (51) | Full Article (XML)-52K (33) | Audio-6033K (5) | Peer-Review Report-205K (25) | Answering Reviewers-249K (37) | Received: 09/11/2025 | Revised: 09/20/2025 | Accepted: 09/28/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1206) | Similar Articles (1483) | Timeline of Article Publication (2) | Cite |

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