Liao YT, Zhu WL. Prognosis of intensive care unit patients with colorectal cancer. World J Gastrointest Oncol 2025; 17(12): 114109 [DOI: 10.4251/wjgo.v17.i12.114109]
Corresponding Author of This Article
Wen-Liang Zhu, PhD, FACP, Professor, Department of Minimally Invasive Intervention, Guangxi Medical University Cancer Hospital, No. 71 Hedi Road, Nanning 530000, Guangxi Zhuang Autonomous Region, China. zhupecker@aliyun.com
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Oncology
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Letter to the Editor
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Dec 15, 2025 (publication date) through Dec 14, 2025
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Publication Name
World Journal of Gastrointestinal Oncology
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1948-5204
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Liao YT, Zhu WL. Prognosis of intensive care unit patients with colorectal cancer. World J Gastrointest Oncol 2025; 17(12): 114109 [DOI: 10.4251/wjgo.v17.i12.114109]
World J Gastrointest Oncol. Dec 15, 2025; 17(12): 114109 Published online Dec 15, 2025. doi: 10.4251/wjgo.v17.i12.114109
Prognosis of intensive care unit patients with colorectal cancer
Yu-Ting Liao, Wen-Liang Zhu
Yu-Ting Liao, Department of Hepatobiliary Surgery, Central South University Xiangya Medical College Affiliated Haikou Hospital, Haikou 570000, Hainan Province, China
Wen-Liang Zhu, Department of Minimally Invasive Intervention, Guangxi Medical University Cancer Hospital, Nanning 530000, Guangxi Zhuang Autonomous Region, China
Author contributions: Liao YT contributed to conceptualization, investigation, and writing of the original draft; Zhu WL contributed to supervision, and critical review and editing. Both authors have reviewed and approved the final version of the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wen-Liang Zhu, PhD, FACP, Professor, Department of Minimally Invasive Intervention, Guangxi Medical University Cancer Hospital, No. 71 Hedi Road, Nanning 530000, Guangxi Zhuang Autonomous Region, China. zhupecker@aliyun.com
Received: September 11, 2025 Revised: September 20, 2025 Accepted: September 28, 2025 Published online: December 15, 2025 Processing time: 91 Days and 1.3 Hours
Abstract
This letter provides commentary on the manuscript “Intensive care unit outcomes and prognostic factors of colorectal cancer”. The study is the first to present multicenter data on the 90-day mortality of patients with colorectal cancer admitted to the intensive care unit, and identifies chemotherapy history, elective surgery, and conventional oxygen therapy as independent prognostic factors. We propose three refinements to enhance the study’s clinical utility: Clarify chemotherapy details, including regimen and treatment phase, along with the surgical approach (curative vs palliative) and how preoperative tumor staging influences prognosis; elucidate the relationship between intensive care unit admission etiologies and prognosis; and incorporate colorectal cancer-specific biomarkers to optimize prognostic scoring systems. The study’s core contribution is substantial, and refinement of the details will further enhance its clinical translational relevance.
Core Tip: This letter comments on the article by Dong et al in the World Journal of Gastrointestinal Oncology, which presents the first multicenter analysis of 90-day mortality data among patients with colorectal cancer admitted to the intensive care unit, and identifies three independent prognostic factors. It proposes clarifying chemo/surgery details, examining the relationship between intensive care unit admission causes and prognosis, and optimizing scoring with colorectal cancer biomarkers to enhance clinical utility.
