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Contents Volume 17 Issue 1 January 24, 2026

Editorial

Beyond sensitivity and specificity: Redefining the era connotation of “low-risk” in pancreatic cancer screening

Rui-Gang Wang

World J Clin Oncol 17(1):116090. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.116090

Abstract (41) | Core Tip (37) | Full Article (HTML) (174) | Figures (1-2) (43) | Full Article (PDF)-647K (43) | Full Article with Cover (PDF)-844K (204) | Full Article (XML)-117K (29) | Audio-1502K (6) | Peer-Review Report-193K (26) | Answering Reviewers-49K (52) | Received: 11/02/2025 | Revised: 11/26/2025 | Accepted: 12/29/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1391) | Similar Articles (0) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Review

Role of nanotechnology in modulating the tumor microenvironment to enhance immunotherapy efficacy

Ayushi Jain, Saloni Verma, Alisha Jadhav, Sharon John, Shalini Gupta

World J Clin Oncol 17(1):111294. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.111294

Abstract (36) | Core Tip (36) | Full Article (HTML) (204) | Figures (1-2) (33) | Tables (1-2) (36) | Full Article (PDF)-1360K (126) | Full Article with Cover (PDF)-1579K (15) | Full Article (XML)-200K (18) | Audio-2583K (7) | Peer-Review Report-191K (15) | Answering Reviewers-178K (15) | Received: 06/26/2025 | Revised: 08/14/2025 | Accepted: 11/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (766) | Similar Articles (155) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Immune landscape of melanoma: Tumor microenvironment, resistance mechanisms, and predictive biomarkers

Marina M G L Oliveira, Carol S Lemos, Mariangela L S Brazão, Alice L A Rodrigues, Evelin da C do Nascimento, Emylli M P Cardoso, Maria F F Arantes, Fabrício F de Melo

World J Clin Oncol 17(1):114913. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.114913

Abstract (37) | Core Tip (53) | Full Article (HTML) (305) | Figures (1-1) (33) | Tables (1-2) (33) | Full Article (PDF)-896K (241) | Full Article with Cover (PDF)-1090K (193) | Full Article (XML)-411K (23) | Audio-718K (12) | Peer-Review Report-192K (30) | Answering Reviewers-66K (28) | Received: 09/30/2025 | Revised: 10/24/2025 | Accepted: 11/27/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (1817) | Similar Articles (57) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Minireviews

Single-cell differential abundance detection: A new angle on dissecting tumor heterogeneity

Ying-Xue Xiao, Jing Sun, Ling-Ling Xie, Yue Zou, Tong Li, You-Jin Hao, Bo Li

World J Clin Oncol 17(1):113244. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.113244

Abstract (38) | Core Tip (53) | Full Article (HTML) (223) | Figures (1-2) (33) | Tables (1-1) (40) | Full Article (PDF)-1551K (54) | Full Article with Cover (PDF)-1746K (368) | Full Article (XML)-192K (19) | Audio-699K (10) | Peer-Review Report-221K (26) | Answering Reviewers-238K (21) | Received: 08/19/2025 | Revised: 09/14/2025 | Accepted: 11/25/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1697) | Similar Articles (2) | Timeline of Article Publication (0) | Authors Evaluation (2) | Article Quality Tracking (0) | Cite |

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Pleiotropic regulation of mitochondrial translational factors in governing proliferation, apoptosis and metastasis during cancer progression

Nikita Agarwal, Uttam Sharma, Akshi Shree, Rajiv Ranjan Kumar, Jaya Kanta Gorain, Vaishnavi Vishwas, Farhana Jahan, Archna Singh, Jayanth Kumar Palanichamy, Deepam Pushpam, Radhika Bakhshi, Anita Chopra, Ranjit Kumar Sahoo, Atul Batra, Surender K Sharawat, Sameer Bakhshi

World J Clin Oncol 17(1):113600. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.113600

Abstract (45) | Core Tip (39) | Full Article (HTML) (258) | Figures (1-4) (32) | Tables (1-1) (43) | Full Article (PDF)-2404K (89) | Full Article with Cover (PDF)-2599K (219) | Full Article (XML)-200K (21) | Audio-1135K (8) | Peer-Review Report-199K (22) | Answering Reviewers-456K (271) | Supplementary Material-903K (19) | Received: 08/29/2025 | Revised: 09/16/2025 | Accepted: 11/26/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1520) | Similar Articles (230) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Arterial and biliary complications after transarterial chemoembolization for hepatocellular carcinoma

Yan-Xin Wan, Zhen-Yi Lin, Lin-Tao Chen, Rong-Qian Wu, Yu Zhang, Zhao-Qing Du

World J Clin Oncol 17(1):113618. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.113618

Abstract (59) | Core Tip (42) | Full Article (HTML) (312) | Figures (1-1) (31) | Tables (1-1) (34) | Full Article (PDF)-1099K (116) | Full Article with Cover (PDF)-1319K (287) | Full Article (XML)-247K (28) | Audio-560K (8) | Peer-Review Report-243K (18) | Answering Reviewers-146K (28) | Received: 08/29/2025 | Revised: 09/24/2025 | Accepted: 12/03/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (1357) | Similar Articles (1911) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Case Control Study

Prognostic significance of PD-L1/PD-1 co-expression and CXCR3-driven inflammatory signatures in Egyptian patients with lymphoproliferative neoplasms

Dalia E Sherief, Nahla Nosair, Aya Mohammed Abdelhameed, Emad Sadaka, Amira A A Othman, Rasha Elgamal

World J Clin Oncol 17(1):112801. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.112801

Abstract (55) | Core Tip (37) | Full Article (HTML) (235) | Figures (1-9) (41) | Tables (1-15) (40) | Full Article (PDF)-2870K (57) | Full Article with Cover (PDF)-3063K (139) | Full Article (XML)-239K (23) | Audio-1095K (11) | Peer-Review Report-223K (13) | Answering Reviewers-440K (18) | Received: 08/05/2025 | Revised: 09/03/2025 | Accepted: 11/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1275) | Similar Articles (0) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Retrospective Cohort Study

Development and internal validation of an immune-based prognostic modeling of early-onset colorectal cancer via machine learning

Xiu Chen, Yong Wang, Heng-Yang Shen, Rui Wu, Zan Fu

World J Clin Oncol 17(1):114238. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.114238

Abstract (34) | Core Tip (47) | Full Article (HTML) (132) | Figures (1-3) (34) | Tables (1-2) (35) | Full Article (PDF)-906K (41) | Full Article with Cover (PDF)-1104K (21) | Full Article (XML)-92K (20) | Audio-1104K (8) | Peer-Review Report-227K (21) | Answering Reviewers-99K (17) | Supplementary Material-348K (15) | Received: 09/17/2025 | Revised: 10/12/2025 | Accepted: 12/01/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1774) | Similar Articles (136) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Retrospective Study

Evaluating murine double minute 2 status as a stratification tool for risk-adapted management in plasma cell neoplasms

Noura A A Ebrahim, Habiba Elfandy, Aya Mohamed Adel Arafat, Amira Diyaa Darwish, Mahitab Ibrahim Eltohamy

World J Clin Oncol 17(1):111426. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.111426

Abstract (34) | Core Tip (40) | Full Article (HTML) (129) | Figures (1-5) (36) | Tables (1-3) (36) | Full Article (PDF)-39104K (37) | Full Article with Cover (PDF)-39326K (21) | Full Article (XML)-85K (16) | Audio-59K (6) | Peer-Review Report-246K (23) | Answering Reviewers-265K (22) | Received: 07/04/2025 | Revised: 07/29/2025 | Accepted: 12/11/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (914) | Similar Articles (0) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Post-treatment triglyceride-glucose index as survival protective factors in patients with esophageal squamous cell carcinoma

Ling Xiao, Yu-Di Liu, Xue Zhang, Shi-Chuan Zhang, Jia-Hua Lyu

World J Clin Oncol 17(1):113304. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.113304

Abstract (38) | Core Tip (45) | Full Article (HTML) (190) | Figures (1-5) (32) | Tables (1-2) (33) | Full Article (PDF)-5008K (95) | Full Article with Cover (PDF)-5204K (128) | Full Article (XML)-114K (21) | Audio-2240K (4) | Peer-Review Report-227K (19) | Answering Reviewers-104K (62) | Received: 08/21/2025 | Revised: 09/16/2025 | Accepted: 12/01/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1338) | Similar Articles (120) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Ferritin as a novel predictive index for nasopharyngeal carcinoma survival and therapeutic efficacy of different chemotherapy regimens

Qi Tang, Yao Wu, Lin Chen, Qun-Ying Jia, Fa-Qing Tang

World J Clin Oncol 17(1):114012. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.114012

Abstract (40) | Core Tip (40) | Full Article (HTML) (201) | Figures (1-9) (33) | Tables (1-5) (35) | Full Article (PDF)-7177K (43) | Full Article with Cover (PDF)-7375K (147) | Full Article (XML)-193K (20) | Audio-1006K (8) | Peer-Review Report-227K (19) | Answering Reviewers-137K (15) | Supplementary Material-654K (22) | Received: 09/11/2025 | Revised: 10/25/2025 | Accepted: 11/25/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1117) | Similar Articles (19) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Mature cystic sacrococcygeal teratoma in adults: A single-center study

Yu Wang, Zhe Wang, Yue-Cui Tang, Yang Li, Xiao-Bo Guo

World J Clin Oncol 17(1):114369. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.114369

Abstract (43) | Core Tip (39) | Full Article (HTML) (163) | Figures (1-4) (34) | Tables (1-7) (32) | Full Article (PDF)-1595K (37) | Full Article with Cover (PDF)-1816K (16) | Full Article (XML)-97K (25) | Audio-220K (7) | Peer-Review Report-224K (19) | Answering Reviewers-26K (23) | Received: 09/16/2025 | Revised: 10/26/2025 | Accepted: 11/25/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1375) | Similar Articles (11) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Clinical Trials Study

Acute exercise-induced catecholaminergic responses after 16 weeks of community-based exercise training in early-stage breast cancer survivors

Jeb F Struder, Aiden J Chauntry, Lauren C Bates-Fraser, Elizabeth P Harrell, Jordan T Lee, Chad W Wagoner, Stephanie A Sullivan, David B Bartlett, Hyman B Muss, Brian C Jensen, Claudio L Battaglini, Erik D Hanson

World J Clin Oncol 17(1):112039. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.112039

Abstract (37) | Core Tip (39) | Full Article (HTML) (217) | Figures (1-2) (32) | Tables (1-4) (38) | Full Article (PDF)-1127K (38) | Full Article with Cover (PDF)-1345K (158) | Full Article (XML)-160K (17) | Audio-974K (8) | Peer-Review Report-223K (14) | Answering Reviewers-327K (16) | Received: 07/15/2025 | Revised: 08/19/2025 | Accepted: 12/08/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1169) | Similar Articles (0) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Observational Study

Patients’ perception of proton pump inhibitors use and their risks

Ibrahim O Sawaied, Abraham O Samson, Efrat Golan

World J Clin Oncol 17(1):113463. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.113463

Abstract (40) | Core Tip (40) | Full Article (HTML) (289) | Figures (1-2) (38) | Tables (1-4) (36) | Full Article (PDF)-562K (56) | Full Article with Cover (PDF)-782K (147) | Full Article (XML)-67K (30) | Audio-39K (5) | Peer-Review Report-196K (25) | Answering Reviewers-72K (29) | Received: 08/25/2025 | Revised: 09/15/2025 | Accepted: 12/23/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1305) | Similar Articles (35) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Kita-Kyushu lung cancer antigen-1 expression in initial gastric tumors predicts multiple cancer development: A pilot study

Nobue Futawatari, Takashi Fukuyama, Yusuke Akimoto, Junji Maehara, Daisuke Hihara, Yosuke Okamoto, Yuki Yokouchi, Kei Takahashi, Manabu Watanabe, Yoshihisa Saida

World J Clin Oncol 17(1):113612. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.113612

Abstract (35) | Core Tip (41) | Full Article (HTML) (140) | Figures (1-2) (33) | Tables (1-4) (34) | Full Article (PDF)-6270K (50) | Full Article with Cover (PDF)-6490K (69) | Full Article (XML)-90K (29) | Audio-1144K (5) | Peer-Review Report-209K (20) | Answering Reviewers-113K (23) | Received: 08/29/2025 | Revised: 10/16/2025 | Accepted: 12/10/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1261) | Similar Articles (0) | Timeline of Article Publication (32) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Meta-Analysis

Obesity and colorectal cancer risk: A systematic review and meta-analysis

Lachlan James Chun-Lok Leung, Rohan Sharad Sharma, Brandon Cheng, HM Kasuni Akalanka, Vinod Gopalan

World J Clin Oncol 17(1):112369. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.112369

Abstract (33) | Core Tip (40) | Full Article (HTML) (407) | Figures (1-5) (35) | Full Article (PDF)-3143K (59) | Full Article with Cover (PDF)-3338K (15) | Full Article (XML)-129K (21) | Audio-3587K (16) | Peer-Review Report-329K (16) | Answering Reviewers-148K (30) | Supplementary Material-275K (26) | Received: 07/24/2025 | Revised: 08/13/2025 | Accepted: 11/27/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1232) | Similar Articles (2116) | Timeline of Article Publication (0) | Authors Evaluation (2) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Case Report

Myeloid sarcoma transformed from myeloproliferative neoplasm: A case report and review of literature

Shu-Han Zhong, Jie Lou, Ai-Qi Zhao, Xue-Li Jin, Shu-Mei Wei, Yun Liang

World J Clin Oncol 17(1):113966. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.113966

Abstract (42) | Core Tip (39) | Full Article (HTML) (170) | Figures (1-2) (35) | Tables (1-1) (35) | Full Article (PDF)-5370K (36) | Full Article with Cover (PDF)-5566K (112) | Full Article (XML)-97K (17) | Audio-1801K (17) | Peer-Review Report-221K (21) | Answering Reviewers-262K (17) | Received: 09/14/2025 | Revised: 11/22/2025 | Accepted: 12/18/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (975) | Similar Articles (4548) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Letter to the Editor

Endoscopic submucosal dissection in early esophageal neoplasia: Celebrating efficacy, confronting heterogeneity, and refining surveillance for high-risk patients

Shi-Qiong Zhou, Qing-Hua Ke

World J Clin Oncol 17(1):113857. Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.113857

Abstract (41) | Core Tip (45) | Full Article (HTML) (139) | Full Article (PDF)-395K (29) | Full Article with Cover (PDF)-591K (16) | Full Article (XML)-53K (14) | Audio-31917K (8) | Peer-Review Report-225K (16) | Answering Reviewers-60K (25) | Received: 09/04/2025 | Revised: 09/27/2025 | Accepted: 12/15/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (671) | Similar Articles (278) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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