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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Jan 24, 2026; 17(1): 113618
Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.113618
Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.113618
Arterial and biliary complications after transarterial chemoembolization for hepatocellular carcinoma
Yan-Xin Wan, Zhen-Yi Lin, Lin-Tao Chen, Yu Zhang, Zhao-Qing Du, Department of Hepatobiliary Surgery, Shaanxi Provincial People’s Hospital, Xi’an 710068, Shaanxi Province, China
Zhen-Yi Lin, National University of Singapore, Singapore 117597, Singapore
Rong-Qian Wu, National Local Joint Engineering Research Center for Precision Surgery and Regenerative Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China
Zhao-Qing Du, National Engineering Research Center for Miniaturized Detection Systems, College of Life Science, Northwest University of Xi’an, Xi’an 710069, Shaanxi Province, China
Author contributions: Wan YX and Du ZQ contributed to conceptualization, data curation, writing - original draft; Lin ZY, Chen LT, Wu RQ, Zhang Y, and Du ZQ contributed to writing-review and editing; Du ZQ contributed to funding acquisition. All authors have read and approved the final manuscript.
Supported by the National Natural Science Foundation of China, No. 82200686.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhao-Qing Du, MD, PhD, Professor, Researcher, Department of Hepatobiliary Surgery, Shaanxi Provincial People’s Hospital, No. 256 West Youyi Road, Xi’an 710068, Shaanxi Province, China. duzhaoqing2007@126.com
Received: August 29, 2025
Revised: September 24, 2025
Accepted: December 3, 2025
Published online: January 24, 2026
Processing time: 144 Days and 0.9 Hours
Revised: September 24, 2025
Accepted: December 3, 2025
Published online: January 24, 2026
Processing time: 144 Days and 0.9 Hours
Core Tip
Core Tip: Transarterial chemoembolization for intermediate-advanced hepatocellular carcinoma carries arterial (stenosis, pseudoaneurysms, hemorrhage) and biliary (fistulas, strictures, cholangitis) complications, with biliary ones more prevalent (hilar tumors/cirrhosis as risk factors). Management involves preoperative imaging, intraoperative superselectivity, and postoperative surveillance, with targeted interventions for each complication type. This review synthesizes recent data to provide a holistic, updated framework for understanding and managing these issues.