Type 2 diabetes exacerbates breast cancer progression through hyperglycaemia, impaired glucose tolerance and insulin resistance, driving a shift toward triple-negative subtypes while reducing human epidermal growth factor receptor 2-positive cases.
Tumor-driven remodeling of the enteric neuroglial niche in gastrointestinal cancer: This schematic summarizes three representative routes by which gastrointestinal tumors reshape the enteric neuroglial niche.
Scatter plots of systemic immune-inflammation index, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio with polyp number.
Immune cells in the tumor microenvironment.
Strategic combination therapies of interleukin-21 for remodeling the tumor microenvironment.
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- Artificial Intelligence in Cancer
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World Journal of Clinical Oncology is an international, peer-reviewed, open-access academic journal dedicated to publishing original, high-quality research findings in the field of oncology, including clinical, translational, and basic studies, as well as research involving artificial intelligence. The journal focuses on, but is not limited to, the following areas: Biology of neoplasia, breast cancer, cancer prevention and control, cancer-related complications, diagnosis in oncology, gastrointestinal cancer, genetic testing for cancer, gynecologic cancer, head and neck cancer, hematologic malignancy, lung cancer, melanoma, molecular oncology, neurooncology, palliative and supportive care, pediatric oncology, surgical oncology, translational oncology, and urologic oncology. Types of articles published by the journal include clinical study, basic study, case report, editorial, review, minireview, systematic review, meta-analysis, guidelines, and correspondence. All submissions undergo a rigorous and transparent peer-review process by at least two independent reviewers. Manuscripts are evaluated based on scientific rigor, originality, clinical relevance, and reproducibility, with particular attention to methodological robustness and data integrity. Constructive and timely feedback is provided to ensure the highest standards of scholarly communication. The journal adheres to the highest standards of publication ethics and editorial integrity, in accordance with the guidelines of the Committee on Publication Ethics, the International Committee of Medical Journal Editors, and the World Association of Medical Editors. To advance scientific discovery, promote evidence-based clinical practice, and foster innovation in oncology, ultimately improving global health outcomes. We invite researchers, clinicians, and multidisciplinary experts worldwide to submit high-quality manuscripts and contribute to shaping the future of oncological science. Submit an Article >>
- Marina Pinheiro, Assistant Professor, (Email: marinabppinheiro@gmail.com) Unidade de Saúde Pública, Unidade Local de Saúde Barcelos/Esposende, Barcelinhos 4755-069, Braga, Portugal; Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Porto 4050-313, Portugal
The 2026 edition of Journal Citation Reports® cites the 2025 journal impact factor (JIF) for WJCO as 3.6; JIF without journal self cites: 3.4; 5-year JIF: 3.8; JIF Rank: 132/333 in oncology; JIF Quartile: Q2; and 5-year JIF Quartile: Q2.
