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Contents Volume 17 Issue 4 April 24, 2026

Editorial

Clinicopathological disparities and prognostic implications of palpable vs non-palpable breast cancer: Toward precision multi-modal early screening strategies

Yu-Tong Han, Yue-Chuan Jiao, Chang Qiao, Hao-Wei Li, De-Hui Li

World J Clin Oncol 17(4):119059. Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.119059

Abstract (51) | Core Tip (44) | Full Article (HTML) (120) | Figures (1-1) (44) | Full Article (PDF)-630K (55) | Full Article with Cover (PDF)-836K (87) | Full Article (XML)-179K (10) | Audio-215K (5) | Peer-Review Report-249K (11) | Answering Reviewers-94K (20) | Received: 01/17/2026 | Revised: 02/05/2026 | Accepted: 03/18/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (585) | Similar Articles (211) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Review

Breast cancer and metabolic comorbidities: From epidemiology and molecular mechanisms to precision interventions

Shen-Hao Zhang, Yang Yang, Yuan Zhang

World J Clin Oncol 17(4):117705. Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.117705

Abstract (51) | Core Tip (42) | Full Article (HTML) (157) | Figures (1-4) (52) | Tables (1-2) (48) | Full Article (PDF)-4175K (57) | Full Article with Cover (PDF)-4382K (57) | Full Article (XML)-348K (12) | Audio-215K (7) | Peer-Review Report-302K (11) | Answering Reviewers-44K (13) | Received: 12/13/2025 | Revised: 01/05/2026 | Accepted: 02/11/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (899) | Similar Articles (211) | Timeline of Article Publication (2) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Host and gut microbiota crosstalk: A new paradigm for colorectal cancer immunotherapy

Dong-Dong Ti, Peng Liu, Chun-Yan Wu, Zhi-Ming Shi, Shu-Ming Guo, Zhan-Cheng Gao

World J Clin Oncol 17(4):118606. Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.118606

Abstract (50) | Core Tip (43) | Full Article (HTML) (93) | Figures (1-3) (47) | Tables (1-1) (47) | Full Article (PDF)-4684K (114) | Full Article with Cover (PDF)-4890K (10) | Full Article (XML)-288K (16) | Audio-1993K (4) | Peer-Review Report-204K (13) | Answering Reviewers-162K (13) | Received: 01/06/2026 | Revised: 01/27/2026 | Accepted: 02/24/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (828) | Similar Articles (1411) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Minireviews

Stroma-nerve axis in pancreatic ductal adenocarcinoma: Bidirectional regulatory mechanisms and clinical translation hypothesis

Yi-Nong Yu, Shui-Quan Jin, Ye-Ting Lu, Lv-Zhou Han

World J Clin Oncol 17(4):117197. Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.117197

Abstract (51) | Core Tip (48) | Full Article (HTML) (94) | Figures (1-3) (46) | Tables (1-1) (45) | Full Article (PDF)-3297K (149) | Full Article with Cover (PDF)-3504K (84) | Full Article (XML)-322K (14) | Audio-243K (4) | Peer-Review Report-193K (11) | Answering Reviewers-109K (8) | Received: 11/30/2025 | Revised: 01/05/2026 | Accepted: 02/24/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (691) | Similar Articles (50) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Precision therapy for driver gene mutations in breast cancer: Current landscape and future perspectives

Zhi-Yong Liu, Ran Chen

World J Clin Oncol 17(4):117540. Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.117540

Abstract (43) | Core Tip (48) | Full Article (HTML) (140) | Tables (1-4) (51) | Full Article (PDF)-450K (31) | Full Article with Cover (PDF)-654K (34) | Full Article (XML)-133K (14) | Audio-10115K (6) | Peer-Review Report-230K (12) | Answering Reviewers-62K (12) | Received: 12/09/2025 | Revised: 01/06/2026 | Accepted: 02/10/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (492) | Similar Articles (211) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Breast cancer in Morocco: Synthesizing two decades of national research to inform future action

Nabil Ismaili, Fadila Guessous, Sanaa El Majjaoui

World J Clin Oncol 17(4):117805. Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.117805

Abstract (61) | Core Tip (53) | Full Article (HTML) (139) | Figures (1-1) (55) | Tables (1-1) (44) | Full Article (PDF)-751K (48) | Full Article with Cover (PDF)-985K (54) | Full Article (XML)-46K (12) | Audio-450K (5) | Peer-Review Report-195K (11) | Answering Reviewers-121K (14) | Received: 12/15/2025 | Revised: 12/26/2025 | Accepted: 02/06/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (826) | Similar Articles (211) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Current perspectives on diagnosis and management of primary and secondary breast endometriosis and potential risk of breast cancer

Alexandra G Marneri, Efstathios T Pavlidis, Kalliopi E Stavrati, Christina Mouratidou, Athanasios Kofinas, Irida Konstantopoulou, Theodoros E Pavlidis

World J Clin Oncol 17(4):118631. Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.118631

Abstract (50) | Core Tip (46) | Full Article (HTML) (138) | Figures (1-1) (45) | Tables (1-2) (43) | Full Article (PDF)-573K (69) | Full Article with Cover (PDF)-780K (85) | Full Article (XML)-148K (12) | Audio-396K (4) | Peer-Review Report-213K (14) | Answering Reviewers-155K (15) | Received: 01/06/2026 | Revised: 01/19/2026 | Accepted: 02/27/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (655) | Similar Articles (33) | Timeline of Article Publication (1) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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New breakthroughs and future trends in renal cell carcinoma therapy: Highlights from the 2025 European Society for Medical Oncology Annual Congress

Zhen-Yu Liu, Yu Zhou, Fu-Han Zhao, Lin Wang, Tie-Jun Pan, Lei Gao

World J Clin Oncol 17(4):118954. Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.118954

Abstract (50) | Core Tip (50) | Full Article (HTML) (172) | Tables (1-1) (62) | Full Article (PDF)-397K (80) | Full Article with Cover (PDF)-631K (110) | Full Article (XML)-101K (10) | Audio-2485K (4) | Peer-Review Report-193K (10) | Answering Reviewers-154K (11) | Received: 01/15/2026 | Revised: 01/29/2026 | Accepted: 03/06/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (717) | Similar Articles (36) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Retrospective Cohort Study

Prognostic value of clinicopathological parameters in adenoid cystic carcinoma: A retrospective cohort study

Katarzyna Stawarz, Anna Gorzelnik, Wojciech Klos, Jacek Korzon, Filip Kissin, Karolina Bienkowska-Pluta, Grzegorz Stawarz, Natalia Rusetska, Jakub Zwoliński

World J Clin Oncol 17(4):116329. Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.116329

Abstract (50) | Core Tip (54) | Full Article (HTML) (151) | Figures (1-1) (54) | Tables (1-6) (44) | Full Article (PDF)-751K (34) | Full Article with Cover (PDF)-959K (41) | Full Article (XML)-137K (10) | Audio-425K (4) | Peer-Review Report-449K (9) | Answering Reviewers-158K (11) | Received: 11/07/2025 | Revised: 11/21/2025 | Accepted: 01/26/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (777) | Similar Articles (4) | Timeline of Article Publication (0) | Article Quality Tracking (1) | Cite |

(0) | (0) | (0) | (0) | Open

Body mass index predicts low muscle mass in esophageal squamous cell carcinoma patients undergoing chemoradiotherapy

Ling Xiao, Yu-Di Liu, Xue Zhang, Shi-Chuan Zhang, Jia-Hua Lyu

World J Clin Oncol 17(4):116601. Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.116601

Abstract (49) | Core Tip (44) | Full Article (HTML) (93) | Figures (1-2) (43) | Tables (1-3) (42) | Full Article (PDF)-1512K (41) | Full Article with Cover (PDF)-1720K (66) | Full Article (XML)-109K (10) | Audio-1378K (5) | Peer-Review Report-337K (12) | Answering Reviewers-346K (21) | Received: 11/14/2025 | Revised: 12/12/2025 | Accepted: 01/21/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (871) | Similar Articles (174) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Retrospective Study

Use of statistical process control to study the patient-specific quality assurance in head and neck cancer

Pratibha Singh, Manoj Kumar Singh, Atul Mishra

World J Clin Oncol 17(4):115851. Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.115851

Abstract (50) | Core Tip (42) | Full Article (HTML) (173) | Figures (1-5) (49) | Tables (1-1) (46) | Full Article (PDF)-5227K (85) | Full Article with Cover (PDF)-5434K (34) | Full Article (XML)-75K (10) | Audio-443K (7) | Peer-Review Report-218K (17) | Answering Reviewers-221K (12) | Received: 10/26/2025 | Revised: 12/10/2025 | Accepted: 02/06/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (911) | Similar Articles (0) | Timeline of Article Publication (0) | Authors Evaluation (2) | Article Quality Tracking (0) | Cite |

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Three kinds of drug-eluting bead transarterial chemoembolisation for treating patients with unresectable non-small cell lung cancer

Hui-Feng Yuan, Dong-Lin Kuang, De-Chao Jiao, Yong-Hua Bi

World J Clin Oncol 17(4):118070. Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.118070

Abstract (48) | Core Tip (51) | Full Article (HTML) (101) | Figures (1-4) (47) | Tables (1-3) (45) | Full Article (PDF)-8819K (31) | Full Article with Cover (PDF)-9027K (19) | Full Article (XML)-95K (10) | Audio-924K (6) | Peer-Review Report-263K (12) | Answering Reviewers-240K (26) | Received: 12/22/2025 | Revised: 01/25/2026 | Accepted: 03/05/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (889) | Similar Articles (83) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Observational Study

Construction and validation of a multiparameter diagnostic model based on conventional tumor markers and cytokines for lung cancer

Yi-Ning Zhang, Tao Jiang, Peng-Jun Zhang, Hui-Juan Wang

World J Clin Oncol 17(4):119365. Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.119365

Abstract (42) | Core Tip (45) | Full Article (HTML) (85) | Figures (1-1) (42) | Tables (1-3) (50) | Full Article (PDF)-787K (23) | Full Article with Cover (PDF)-1003K (47) | Full Article (XML)-88K (12) | Audio-1737K (5) | Peer-Review Report-226K (12) | Answering Reviewers-49K (10) | Received: 01/30/2026 | Revised: 02/10/2026 | Accepted: 03/06/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (744) | Similar Articles (125) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Prospective Study

Longitudinal microRNA profiles in breast cancer tissue and plasma: Associations with hormone receptors, response, and survival

Dinara Ryspayeva, Attila A Seyhan, Kaizhong Mu, Mengyue Liu, Connor Purcell, William J MacDonald, Volodymyr Halytskiy, Tetiana Drevytska, Mariia Inomistova, Natalia Khranovska, Oleksandr Potorocha, Lesia Taran, Olena Sumkina, Ivan Smolanka Sr, Wafik S El-Deiry

World J Clin Oncol 17(4):115287. Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.115287

Abstract (47) | Core Tip (45) | Full Article (HTML) (188) | Figures (1-9) (48) | Tables (1-4) (44) | Full Article (PDF)-5077K (57) | Full Article with Cover (PDF)-5280K (57) | Full Article (XML)-328K (14) | Audio-1813K (8) | Peer-Review Report-190K (14) | Answering Reviewers-82K (10) | Supplementary Material-1156K (13) | Received: 10/12/2025 | Revised: 11/19/2025 | Accepted: 03/02/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1144) | Similar Articles (211) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Systematic Reviews

MicroRNAs as diagnostic and prognostic biomarkers in chemotherapy-induced peripheral neuropathy: A systematic review

Tsampika-Vasileia Kalamara, Dimitrios A Andreikos, Konstantinos Dodos, Elisavet Georgiou, George Fotakopoulos, Nikolaos Foroglou, Dorothea Kapoukranidou, Vasiliki E Georgakopoulou

World J Clin Oncol 17(4):117460. Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.117460

Abstract (52) | Core Tip (44) | Full Article (HTML) (119) | Figures (1-4) (49) | Tables (1-4) (47) | Full Article (PDF)-3719K (60) | Full Article with Cover (PDF)-3923K (71) | Full Article (XML)-150K (14) | Audio-1874K (6) | Peer-Review Report-185K (11) | Answering Reviewers-112K (10) | Supplementary Material-70K (23) | Received: 12/07/2025 | Revised: 12/26/2025 | Accepted: 03/20/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (670) | Similar Articles (119) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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