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Contents Volume 17 Issue 5 May 24, 2026

Editorial

Immune checkpoint co-expression combined with systemic inflammatory index: A promising approach in prognostic evaluation of lymphoma in Egypt

Zu-Chian Chiang, Ji-Zhen Lin, Qi Chen

World J Clin Oncol 17(5):117391. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.117391

Abstract (12) | Core Tip (8) | Full Article (HTML) (33) | Figures (1-1) (7) | Tables (1-1) (11) | Full Article (PDF)-819K (5) | Full Article with Cover (PDF)-1040K (3) | Full Article (XML)-80K (2) | Audio-195K (3) | Peer-Review Report-229K (1) | Answering Reviewers-125K (1) | Received: 12/05/2025 | Revised: 02/02/2026 | Accepted: 03/10/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (123) | Similar Articles (5) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Evidence Review

Role of lactylation in tumorigenesis: Analysis based on the ten hallmarks of cancer

Jin-Hao Chen, Jiang-Qiuchen Wu, Cun-Ming Lv

World J Clin Oncol 17(5):113527. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.113527

Abstract (7) | Core Tip (8) | Full Article (HTML) (31) | Figures (1-3) (7) | Tables (1-1) (8) | Full Article (PDF)-2036K (2) | Full Article with Cover (PDF)-2256K (2) | Full Article (XML)-203K (1) | Audio-962K (3) | Peer-Review Report-217K (1) | Answering Reviewers-268K (1) | Received: 08/27/2025 | Revised: 09/18/2025 | Accepted: 03/10/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (132) | Similar Articles (2) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Minireviews

Diabetes mellitus and ovarian cancer: Intersecting pathways and clinical outcomes

Tirath Patel, Sara Kareem Ali, Yusur Jawad, Seba Hasan Haddad, Liyan Mahmoud Al Masri, Aya Rimawi, Reem Ahmed Alraeesi, Hessah Sultan Alkaabi, Muhammad Farhan, Maheen Zahid, Muhammad Ahmad, Neha Choudhary, Muhammad Hashir Nazir, Ayoola Awosika

World J Clin Oncol 17(5):117365. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.117365

Abstract (16) | Core Tip (10) | Full Article (HTML) (71) | Figures (1-2) (8) | Tables (1-1) (7) | Full Article (PDF)-1946K (6) | Full Article with Cover (PDF)-2194K (5) | Full Article (XML)-122K (2) | Audio-4182K (3) | Peer-Review Report-218K (4) | Answering Reviewers-56K (2) | Received: 12/05/2025 | Revised: 12/19/2025 | Accepted: 03/10/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (256) | Similar Articles (231) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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DNA methylation in gastric precancerous lesions: Molecular mechanisms and clinical translation

Si-Hui Zeng, Yu-Qi Wu, Wei-Jian Zhang, Yi-Tian Wang, Lin Xu, Shao-Ju Guo

World J Clin Oncol 17(5):118073. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.118073

Abstract (12) | Core Tip (9) | Full Article (HTML) (21) | Figures (1-3) (7) | Tables (1-1) (7) | Full Article (PDF)-3169K (2) | Full Article with Cover (PDF)-3386K (1) | Full Article (XML)-147K (3) | Audio-12072K (2) | Peer-Review Report-262K (2) | Answering Reviewers-110K (1) | Received: 12/22/2025 | Revised: 02/12/2026 | Accepted: 03/26/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (244) | Similar Articles (40) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Immunomodulatory and antitumor effects of shilajit and glycine: Natural metabolic modulators targeting breast and liver cancer

Tasneem A Basbrain, Nidal M Zabermawi, Jehan S Alrahimi, Kawther A Zaher

World J Clin Oncol 17(5):119163. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.119163

Abstract (10) | Core Tip (8) | Full Article (HTML) (25) | Figures (1-6) (7) | Tables (1-2) (7) | Full Article (PDF)-5623K (3) | Full Article with Cover (PDF)-5868K (1) | Full Article (XML)-194K (1) | Audio-835K (1) | Peer-Review Report-241K (2) | Answering Reviewers-130K (1) | Received: 01/19/2026 | Revised: 02/06/2026 | Accepted: 03/13/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (172) | Similar Articles (2) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Integration of pathomics and single-cell omics in pancreatic ductal adenocarcinoma: Applications and clinical translation prospects

Xin Yan, Hong-Yu Xu, Jia-Wu Liu, Zhi-Yong Yang, Qian Zhu

World J Clin Oncol 17(5):119864. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.119864

Abstract (8) | Core Tip (10) | Full Article (HTML) (19) | Figures (1-2) (9) | Tables (1-2) (7) | Full Article (PDF)-8927K (3) | Full Article with Cover (PDF)-9144K (2) | Full Article (XML)-316K (1) | Audio-2028K (1) | Peer-Review Report-210K (1) | Answering Reviewers-125K (3) | Received: 02/07/2026 | Revised: 02/17/2026 | Accepted: 03/16/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (184) | Similar Articles (52) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Case Control Study

Prognostic value of lung immune prognostic index in stage I non-small cell lung cancer treated with stereotactic body radiotherapy: A two-center study

Wei-Hua Gao, Hui Luo, Qing-Yao Zhu, Qiang Jiang, Li-Xia Lian

World J Clin Oncol 17(5):120140. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.120140

Abstract (9) | Core Tip (8) | Full Article (HTML) (21) | Figures (1-1) (7) | Tables (1-2) (7) | Full Article (PDF)-644K (3) | Full Article with Cover (PDF)-867K (1) | Full Article (XML)-86K (2) | Audio-773K (1) | Peer-Review Report-255K (1) | Answering Reviewers-177K (1) | Received: 02/15/2026 | Revised: 03/15/2026 | Accepted: 04/10/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (180) | Similar Articles (63) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Retrospective Cohort Study

Integrated Chinese and Western medicine prolong survival in colorectal cancer with liver metastasis: A retrospective cohort study

Jiang-Yu Bian, Yu-Xing Sun, Lin-Feng Wang, Wen-Ting He, Chuan-Bo Liu, Xue-Qian Wang, Tong Zhang

World J Clin Oncol 17(5):118265. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.118265

Abstract (9) | Core Tip (8) | Full Article (HTML) (17) | Figures (1-2) (7) | Tables (1-4) (8) | Full Article (PDF)-1463K (4) | Full Article with Cover (PDF)-1685K (2) | Full Article (XML)-73K (2) | Audio-666K (5) | Peer-Review Report-208K (2) | Answering Reviewers-195K (3) | Received: 01/03/2026 | Revised: 02/12/2026 | Accepted: 04/15/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (328) | Similar Articles (16) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Retrospective Study

Hepatic resection in adolescent and young adult patients with hepatocellular carcinoma

Junji Ueda, Nobuhiko Taniai, Masato Yoshioka, Akira Matsushita, Satoshi Mizutani, Yoichi Kawano, Tetsuya Shimizu, Tomohiro Kanda, Takahiro Murokawa, Hideyuki Takata, Hiroyasu Furuki, Yuto Aoki, Mampei Kawashima, Toshiyuki Irie, Takashi Ono, Takahiro Haruna, Daigo Yoshimori, Kazuhiko Endo, Akira Hamaguchi, Hiroshi Yoshida

World J Clin Oncol 17(5):117168. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.117168

Abstract (10) | Core Tip (9) | Full Article (HTML) (22) | Figures (1-5) (7) | Tables (1-3) (7) | Full Article (PDF)-22161K (5) | Full Article with Cover (PDF)-22410K (2) | Full Article (XML)-71K (1) | Audio-538K (2) | Peer-Review Report-277K (2) | Answering Reviewers-56K (2) | Received: 11/29/2025 | Revised: 01/23/2026 | Accepted: 02/24/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (264) | Similar Articles (1880) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Comparison of dagnostic performance between senior and junior radiologists using subjective assessment vs ovarian-adnexal reporting and data system

Hui-Ping Zhang, Quan Zhu, Jing-Jing Wu, An-Qiang Yang, Tian-Tian Chen, Juan Zhang, Yu-Qing Zhou

World J Clin Oncol 17(5):119512. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.119512

Abstract (8) | Core Tip (8) | Full Article (HTML) (16) | Figures (1-1) (7) | Tables (1-1) (9) | Full Article (PDF)-1956K (1) | Full Article with Cover (PDF)-2205K (1) | Full Article (XML)-68K (1) | Audio-1438K (2) | Peer-Review Report-207K (1) | Answering Reviewers-57K (2) | Received: 02/06/2026 | Revised: 03/26/2026 | Accepted: 04/13/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (173) | Similar Articles (2) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Observational Study

Psychological flexibility and coping behaviors in cervical cancer patients: Moderating role of illness perception

Yan-Fei Di, Zhen Zhang, Qian Li, Xue Han, Qin Chen, Xin-Ying He, Peng-Fei Xu, Hai-Xiang Wang

World J Clin Oncol 17(5):120810. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.120810

Abstract (8) | Core Tip (8) | Full Article (HTML) (23) | Tables (1-4) (8) | Full Article (PDF)-450K (3) | Full Article with Cover (PDF)-680K (8) | Full Article (XML)-91K (1) | Audio-425K (1) | Peer-Review Report-223K (1) | Answering Reviewers-123K (1) | Received: 03/08/2026 | Revised: 04/10/2026 | Accepted: 04/23/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (143) | Similar Articles (35) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Prospective Study

Clinicopathological and prognostic relevance of nestin in low- and high-grade gliomas: An immunohistochemical study

Sabeen Nasir, Asif Ali, Ihsan Ullah, Shabnam Wazir, Irum Javaid, Summaya Z Jalal, Ishaq Khan, Muhammed Mubarak

World J Clin Oncol 17(5):118350. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.118350

Abstract (9) | Core Tip (8) | Full Article (HTML) (21) | Figures (1-3) (7) | Tables (1-3) (7) | Full Article (PDF)-15786K (2) | Full Article with Cover (PDF)-16034K (3) | Full Article (XML)-85K (2) | Audio-1151K (1) | Peer-Review Report-192K (1) | Answering Reviewers-192K (1) | Received: 12/29/2025 | Revised: 01/10/2026 | Accepted: 03/09/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (167) | Similar Articles (0) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Basic Study

Overexpression of low-molecular-weight caldesmon is associated with aggressive phenotypes and epithelial-mesenchymal transition in breast cancer cells

Alya AlNuaimi, Vidhya A Nair, Noura Al-Khayyal, Ashna Suliman, Lara J Bou Malhab, Rifat Hamoudi, Mohamad Hamad, Iman M Talaat, Wael M Abdel-Rahman

World J Clin Oncol 17(5):116662. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.116662

Abstract (7) | Core Tip (8) | Full Article (HTML) (20) | Figures (1-9) (7) | Tables (1-3) (8) | Full Article (PDF)-16291K (1) | Full Article with Cover (PDF)-16535K (2) | Full Article (XML)-145K (1) | Audio-1044K (1) | Peer-Review Report-252K (2) | Answering Reviewers-64K (1) | Supplementary Material-325K (4) | Received: 11/17/2025 | Revised: 01/27/2026 | Accepted: 03/02/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (266) | Similar Articles (251) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Identification of SRSF2 as a potential immunodiagnostic biomarker for osteosarcoma: A study based on focused protein microarray

Yan Ma, Lei Wan, Yong-Yong Zhang, Ya-Ge Luo, Ning Yang, Fei-Fei Pu, Malik Ihsan Ullah Khan, Man Liu, Jin-Shan Liu, Ji-Tian Li

World J Clin Oncol 17(5):119275. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.119275

Abstract (9) | Core Tip (8) | Full Article (HTML) (19) | Figures (1-3) (7) | Tables (1-2) (8) | Full Article (PDF)-5971K (2) | Full Article with Cover (PDF)-6194K (2) | Full Article (XML)-151K (1) | Audio-1133K (2) | Peer-Review Report-211K (1) | Answering Reviewers-170K (1) | Supplementary Material-335K (3) | Received: 01/23/2026 | Revised: 02/11/2026 | Accepted: 03/26/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (208) | Similar Articles (70) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Meta-Analysis

Impact of surgery for colorectal cancer liver metastasis: Systematic review and meta-analysis

Fausto Petrelli, Sara Cherri, Antonio Ghidini, Mauro Rossitto, Roberta Bukovec, Luisa Roncari, Lorenzo Dottorini, Marcella Arru, Michela Libertini, Alberto Zaniboni

World J Clin Oncol 17(5):118670. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.118670

Abstract (10) | Core Tip (7) | Full Article (HTML) (27) | Figures (1-3) (7) | Tables (1-2) (9) | Full Article (PDF)-1092K (6) | Full Article with Cover (PDF)-1314K (2) | Full Article (XML)-227K (1) | Audio-666K (3) | Peer-Review Report-392K (1) | Answering Reviewers-333K (1) | Supplementary Material-60K (2) | Received: 01/07/2026 | Revised: 02/06/2026 | Accepted: 03/18/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (144) | Similar Articles (1987) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Intracystic glucose is superior to carcinoembryonic antigen in diagnosing mucinous pancreatic cysts in genomic era: Systematic review and meta-analysis

Giacomo Emanuele Maria Rizzo, Giuseppe Infantino, Giovanni Marchegiani, Jorge D Machicado, Marco Del Chiaro, Ilaria Tarantino, Gemma Rossi, Paolo Giorgio Arcidiacono, Giuseppe Vanella, Lucia Guilabert, Sara Nikolić, Gabriele Capurso

World J Clin Oncol 17(5):120600. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.120600

Abstract (8) | Core Tip (9) | Full Article (HTML) (20) | Figures (1-5) (7) | Tables (1-1) (7) | Full Article (PDF)-4096K (3) | Full Article with Cover (PDF)-4318K (1) | Full Article (XML)-175K (1) | Audio-2269K (1) | Peer-Review Report-219K (1) | Answering Reviewers-409K (1) | Supplementary Material-1897K (2) | Received: 03/02/2026 | Revised: 03/14/2026 | Accepted: 04/20/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (117) | Similar Articles (1) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Case Report

Clinical presentation and management of hereditary gingival fibromatosis: Four case reports

Yuan Cheng, Jie Zhao, Jie Yang, Liang-Yuan Lin, Juan Wu

World J Clin Oncol 17(5):119443. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.119443

Abstract (8) | Core Tip (9) | Full Article (HTML) (17) | Figures (1-7) (7) | Full Article (PDF)-10592K (2) | Full Article with Cover (PDF)-10840K (1) | Full Article (XML)-58K (1) | Audio-771K (1) | Peer-Review Report-306K (2) | Answering Reviewers-117K (4) | Received: 01/28/2026 | Revised: 02/23/2026 | Accepted: 03/19/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (101) | Similar Articles (4557) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Anlotinib plus albumin-bound paclitaxel induction-maintenance for sorafenib-refractory radioiodine-refractory differentiated thyroid cancer: A case report and review of literature

Chun-Yan Zhou, Xin-Yi Ren, Huan-Huan Li, Xiao-Mei Pan, Xin Lan, Dong Duan

World J Clin Oncol 17(5):119615. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.119615

Abstract (8) | Core Tip (9) | Full Article (HTML) (18) | Figures (1-5) (7) | Tables (1-1) (8) | Full Article (PDF)-10220K (1) | Full Article with Cover (PDF)-10468K (1) | Full Article (XML)-116K (1) | Audio-807K (4) | Peer-Review Report-220K (1) | Answering Reviewers-566K (2) | Received: 02/01/2026 | Revised: 03/06/2026 | Accepted: 04/01/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (214) | Similar Articles (4560) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Abdominal nodal metastasis from an unknown primary: A case report and review of literature

Yi Lu, Qi Zhu, Yao Xiao, Ru-Yan Pan, Ling-Hui Deng, Qi Zhang, Yue Wang

World J Clin Oncol 17(5):120273. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.120273

Abstract (10) | Core Tip (8) | Full Article (HTML) (21) | Figures (1-3) (7) | Full Article (PDF)-9734K (1) | Full Article with Cover (PDF)-9982K (1) | Full Article (XML)-73K (1) | Audio-797K (1) | Peer-Review Report-219K (2) | Answering Reviewers-262K (1) | Received: 02/21/2026 | Revised: 03/13/2026 | Accepted: 03/27/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (205) | Similar Articles (4556) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Correspondence

Letter to the Editor: Revisiting the anatomical pattern of bone metastases in stage IV breast cancer: Missing clinical stratification and biological depth

Pei-Zhi Zhang, Yan-Jie Wang, Ying-Kun Xu

World J Clin Oncol 17(5):114734. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.114734

Abstract (9) | Core Tip (10) | Full Article (HTML) (23) | Full Article (PDF)-347K (3) | Full Article with Cover (PDF)-597K (3) | Full Article (XML)-28K (1) | Audio-301K (1) | Peer-Review Report-193K (2) | Answering Reviewers-62K (2) | Received: 09/26/2025 | Revised: 12/01/2025 | Accepted: 02/03/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (87) | Similar Articles (218) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Letter to the Editor: Deep margin positivity in small rectal neuroendocrine tumors - pathological insights for post-endoscopic submucosal dissection management

Ling-Feng Zou, Yan Luo, Cheng-Long Wang

World J Clin Oncol 17(5):117161. Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.117161

Abstract (8) | Core Tip (9) | Full Article (HTML) (16) | Full Article (PDF)-352K (2) | Full Article with Cover (PDF)-600K (1) | Full Article (XML)-40K (1) | Audio-592K (1) | Peer-Review Report-258K (3) | Answering Reviewers-126K (1) | Received: 11/29/2025 | Revised: 01/20/2026 | Accepted: 02/13/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (101) | Similar Articles (243) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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