Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Clin Oncol. May 24, 2026; 17(5): 119443
Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.119443
Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.119443
Clinical presentation and management of hereditary gingival fibromatosis: Four case reports
Yuan Cheng, Jie Zhao, Jie Yang, Juan Wu, Department of Periodontology, Nanjing Stoma
Liang-Yuan Lin, Department of Stomatology, Children’s Hospital of Nanjing Medical University, Nanjing 210008, Jiangsu Province, China
Author contributions: Cheng Y, Zhao J, and Yang J collected the clinical data and performed the clinical management; Cheng Y drafted the manuscript; Wu J and Lin LY designed the research study; Wu J critically revised the manuscript for important intellectual content; and all authors have read and approved the final manuscript.
Supported by the General Clinical Trial Project of Nanjing Medical Science and Technology Development Fund, No. LYM25020; “3456” Cultivation Program for Junior Talents of Nanjing Stomatological School, Medical School of Nanjing University, No. 0222C104.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Juan Wu, MDS, PhD, Associate Professor, Department of Perio
Received: January 29, 2026
Revised: February 23, 2026
Accepted: March 19, 2026
Published online: May 24, 2026
Processing time: 113 Days and 0.2 Hours
Revised: February 23, 2026
Accepted: March 19, 2026
Published online: May 24, 2026
Processing time: 113 Days and 0.2 Hours
Core Tip
Core Tip: Periodontal surgery is effective for managing hereditary gingival fibromatosis (HGF) by exposing unerupted teeth and establishing an appropriate gingival contour. Early intervention, multidisciplinary treatment programs, and long-term follow-up are essential for achieving optimal outcomes in HGF.