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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Jan 24, 2026; 17(1): 113966
Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.113966
Published online Jan 24, 2026. doi: 10.5306/wjco.v17.i1.113966
Myeloid sarcoma transformed from myeloproliferative neoplasm: A case report and review of literature
Shu-Han Zhong, Ai-Qi Zhao, Xue-Li Jin, Yun Liang, Department of Hematology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
Jie Lou, Department of Hematology, Xiaoshan People’s Hospital, Hangzhou 311200, Zhejiang Province, China
Shu-Mei Wei, Department of Pathology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310000, Zhejiang Province, China
Co-first authors: Shu-Han Zhong and Jie Lou.
Co-corresponding authors: Shu-Mei Wei and Yun Liang.
Author contributions: Zhong SH and Lou J were involved in the clinical management of the patient, conceptualized the case report, and drafted the initial manuscript; both authors made indispensable contributions to the completion of this work and qualify as co-first authors. Zhao AQ and Jin XL participated in the therapeutic management of the patient and critically reviewed the manuscript. Wei SM and Liang Y were responsible for preparing/submitting the manuscript and supplementary files, managing all correspondence with the editorial office, ensuring final manuscript approval by all authors; Wei SM conducted literature searches and revised/submitted the early manuscript version with a focus on disease pathogenesis and therapeutic progression, while Liang Y collated published similar cases and performed integrated analyses of pathological subtypes and treatment outcomes. Wei SM and Liang Y contributed equally as co-corresponding authors.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors declare no known conflicts of interest related to this work. No financial, professional, or personal relationships with other people or organizations that could inappropriately influence (bias) this study have been reported.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yun Liang, MD, PhD, Professor, Department of Hematology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, No. 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China. liangyun@zju.edu.cn
Received: September 16, 2025
Revised: November 22, 2025
Accepted: December 18, 2025
Published online: January 24, 2026
Processing time: 127 Days and 20.7 Hours
Revised: November 22, 2025
Accepted: December 18, 2025
Published online: January 24, 2026
Processing time: 127 Days and 20.7 Hours
Core Tip
Core Tip: This paper details the diagnosis and treatment process of an elderly male patient whose condition transformed from myelofibrosis to myeloid sarcoma. The diagnosis was confirmed through multiple examinations. This case highlights the significant impact of accurate diagnosis and flexible adjustment of treatment plans on patients' survival under complex disease conditions.