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Contents Volume 18 Issue 7 July 15, 2026
Editorial
Modified frailty index and systemic immune-inflammation enable biological risk stratification in geriatric colorectal cancer surgery
Kai-Zhen Xu, Wen-Jian Hu, Yu-Hui Shang, Yan-Dong Miao, Li-Na Wang 
World J Gastrointest Oncol 18(7):119003. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.119003
Opinion Review
Early detection of pancreatic cancer by evaluating combined serum biomarker: The key questions
Fatima Noor, Muhammad Saif Ur Rehman, Umme E Ambreen, Tayyeba Sattar 
World J Gastrointest Oncol 18(7):115270. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.115270
Novel regulatory network of PS-1/β-catenin/p-PTEN axis in gastric cancer invasion
Shuai Xiao, Dan-Dan Song, Ye-Ping Yu, Xiao-Zhen Xu, Jing-Feng Tang, Ce-Fan Zhou 
World J Gastrointest Oncol 18(7):118256. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.118256
Minireviews
Artificial intelligence in quantitative imaging of esophageal cancer: A review on radiomics, sarcopenia, and survival modeling
Sivan Sathish, Ankita Jain, Kratee Sharma, Karthika B 
World J Gastrointest Oncol 18(7):119986. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.119986
New-onset diabetes and pancreatic cancer: Current evidence on absolute risk and screening feasibility
Seoung Hoon Kim 
World J Gastrointest Oncol 18(7):121817. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.121817
Retrospective Cohort Study
Prophylactic sodium thiosulfate reduces the risk and severity of acute kidney injury in oxaliplatin-based hyperthermic intraperitoneal chemotherapy
Nader Algethami, Valentinus Valdimarsson, Victor Verwaal, Ingvar Syk 
World J Gastrointest Oncol 18(7):118400. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.118400
Prognostic factors and optimal timing for initiating adjuvant chemotherapy in stage IIIC gastric cancer
Jun-Wei Wu, Fan Li, Shi-Dian Wang, Yu-Kun Guo, Bing-Huang Li, Xin Zhou, Guo-Qiang Su, Chuan-Hui Lu 
World J Gastrointest Oncol 18(7):119040. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.119040
Interpretable multimodal artificial intelligence model for predicting advanced neoplasia in pancreatic cystic lesions
Yavuz Özden, Ömer Yüzügülen, Ferhat Omurca 
World J Gastrointest Oncol 18(7):119847. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.119847
Factors associated with complete clinical response after neoadjuvant therapy in locally advanced rectal cancer: A Mexican retrospective study
Ismael Brito-Toledo, Jesús Alberto Sansón-Riofrío, Maria Teresa Cervantes-Díaz, Jazmín de Anda-González, Rafael Medrano-Guzmán, Emilio Moreno-González, Eduardo Vadillo, Antonio Ibarra 
World J Gastrointest Oncol 18(7):119971. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.119971
Impact of textbook outcome after hepatectomy for colorectal metastases on salvage curative-intent treatment at recurrence
Long Chen, Hua-Chuan Song, Fan-Zheng Meng, Shen-Yu Zhang, Ze-Yang An, Xin-Yu Ling, Can Zhang, Xing-Chun Zhu, Ji-Zhou Wang, Rui-Peng Song, Lian-Xin Liu 
World J Gastrointest Oncol 18(7):120704. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.120704
Prognostic value of pan-immune-inflammation index in hepatocellular carcinoma compared with albumin-bilirubin and model for end-stage liver disease sodium
Salih Karatlı, Doğan Yazılıtaş, Seher Kaya, Gökşen İ İmamoğlu, Selahattin Çelik, Galip C Uyar 
World J Gastrointest Oncol 18(7):121250. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.121250
Retrospective Study
OncoVee™-mini-patient-derived xenograft guided adjuvant chemotherapy treatment for resectable gastric cancer
Yu-Xuan Qiu, Kai-Yu Jian, Qian-Ru Xu, Xin Lu, Bao-Lei Jia, Lin Jiang, Feng Liang 
World J Gastrointest Oncol 18(7):118050. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.118050
Association between geriatric nutritional risk index and colorectal adenoma risk in an asymptomatic screening population
Xue-Yan Niu, Dan Wang, Fei Chen, Yi-Zhe Yang, Kai Meng, Yang-Xuan Du, Bin Liu 
World J Gastrointest Oncol 18(7):118372. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.118372
Lenvatinib and pembrolizumab plus FOLFOX-hepatic arterial infusion chemotherapy in locally advanced, potentially resectable hepatocellular carcinoma
Xi Chen, Hao Liao, Jie Chen, Lin-Hui Peng, Ji-Hao Zhang, Xiu-Xiu Xuyun, Ya-Jin Chen, Tao Chen 
World J Gastrointest Oncol 18(7):118522. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.118522
Process-based nursing using explanation-simulation-practice-communication-support model for pain management after liver cancer intervention
Ri-Hong Qian, Yan Xu 
World J Gastrointest Oncol 18(7):118632. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.118632
Endoscopic ultrasonography lesion thickness predicts deep invasion in gastric cancer: Development and temporal validation of a preoperative model
Meng-Yu Cao, Yu-Fan Chen, Yun-Xiu Liao, Qing Yang, Shi-Yong Lin, Yin Li, Jun Weng, Xin-Xin Huang, Xiao-Yan Gao, Guo-Bao Wang, Hong-Bo Shan, Jian-Jun Li 
World J Gastrointest Oncol 18(7):118867. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.118867
ST2, PIVKA-II, CEA, CA125 and their combinations in elderly liver metastases cancers: Development of a diagnostic scoring model
Yun Cheng, Yan-Sha Sun, Yong-Ming He 
World J Gastrointest Oncol 18(7):118940. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.118940
Comparative analysis of curative efficacy and prognostic factors across treatment modalities for early-stage hepatocellular carcinoma (BCLC 0/A)
Wen Zheng, Ping Lv, Qiang Zhu, Qing-Lin Zhang, Gang-Gang Yin, Wei-Gang Chen 
World J Gastrointest Oncol 18(7):119136. Published online Jul 15, 2026. doi: 10.4251/wjgo.119136
Impact of anxiety and depression on quality of life in gastric cancer patients receiving SOX neoadjuvant chemotherapy
Bo-Yang Cui, Zhen Zhang 
World J Gastrointest Oncol 18(7):119170. Published online Jul 15, 2026. doi: 10.4251/wjgo.119170
Development and clinical application of an ultrasound-based deep learning model for preoperative staging of colorectal cancer
Jing Zhao, Li-Juan Du, Ying Liu, Dan-Dan Zhu, Hui-Qing Wang, Ming-Kui Shen, Ling-Yue Wang, Hai-Yan Wang 
World J Gastrointest Oncol 18(7):120437. Published online Jul 15, 2026. doi: 10.4251/wjgo.120437
Prognostic significance of germline ARID5B and LEPR polymorphisms in intrahepatic and perihilar cholangiocarcinoma after curative resection
Guanwu Wang, Carlos Otto, Dong Liu, Tarick M Al-Masri, Smiths S Lueong, Jens Siveke, Tom Luedde, Daniel Heise, Florian WR Vondran, Franziska Alexandra Meister, Georg Lurje, Ulf Neumann, Lara Heij, Jan Bednarsch 
World J Gastrointest Oncol 18(7):120469. Published online Jul 15, 2026. doi: 10.4251/wjgo.120469
Clinical study predicting prolonged postoperative ileus after laparoscopic colorectal cancer surgery with intelligent bowel sound auscultation system
Shuai Shi, Chong Wang, Chen-Si Zhao, Zun Chen, Liang Yan, Yong Liang, Xin Yue, Xiang-Long Duan, Zuo-Zheng Wang 
World J Gastrointest Oncol 18(7):120582. Published online Jul 15, 2026. doi: 10.4251/wjgo.120582
Synergistic value of systemic inflammatory and tumor markers in predicting pretreatment distant metastasis of gastric cancer
Yu-Meng Shen, Xiao-Yu Hong, Hao-Chun Gao, Qiu-Lin Hao, Zheng-Yu Li, Zhi-Yuan Yao, Chao Gao 
World J Gastrointest Oncol 18(7):120785. Published online Jul 15, 2026. doi: 10.4251/wjgo.120785
Emergency presentation predicts advanced pathological stage in colorectal cancer: An ordinal regression analysis
Osman G Gökdere, Burhan H Kanat 
World J Gastrointest Oncol 18(7):120893. Published online Jul 15, 2026. doi: 10.4251/wjgo.120893
Trends, clinicopathological features, and prognosis of 687 cases of early-onset gastric cancer: A single-center, retrospective study
Hui-Qing Zhang, Wei-Lei Wu, Jia-Xin Huang, Shu-Ping Xiong, Xiao-Dan Chen 
World J Gastrointest Oncol 18(7):122188. Published online Jul 15, 2026. doi: 10.4251/wjgo.122188
Observational Study
Association between physical activity and early-stage gastric cancer: A cross-sectional study of the Wuwei cohort
Hao Yuan, Qin Sun, Zhe Wang, Xi-Dong Fang, Jing Yang, Zhi-Yu Wu, Xin-Hong Cheng, Ya Zheng, Yong-Ning Zhou 
World J Gastrointest Oncol 18(7):119682. Published online Jul 15, 2026. doi: 10.4251/wjgo.119682
Prospective Study
Prognostic nomogram model for overall survival in patients with hepatocellular carcinoma
Jing-Yu Tan, Jing-Xian Yang, Qian-Jie Xu, Yu-Lan Zhao, Wei Zhang, Xiao-Sheng Li 
World J Gastrointest Oncol 18(7):120724. Published online Jul 15, 2026. doi: 10.4251/wjgo.120724
Basic Study
Yiwei Xiaoyu granules mitigate spasmolytic polypeptide-expressing metaplasia-associated gastric mucosal damage by regulating WFDC2 and the miRNA-7/circRNA network
Wan-Qun Chen, Ying-Yue Xu, He-Lin Pan, Min Duan, Hang Ma, Yan-Ping Li, Jin-Wei Zhang 
World J Gastrointest Oncol 18(7):118787. Published online Jul 15, 2026. doi: 10.4251/wjgo.118787
IGF2BP1 promotes gastric cancer progression by stabilizing HS6ST2 mRNA in an N6-methyladenosine-dependent manner
Lu Liu, Yi-Jing Zhou, Yue Xu, Qian-Qian Yin, Jue-Jue Wang, Shan-Jing Xu, Ling-Ling Yan, Zhen-Zhen Wang, Shao-Wei Li, Xin-Li Mao, Yu Zhang 
World J Gastrointest Oncol 18(7):119282. Published online Jul 15, 2026. doi: 10.4251/wjgo.119282
Evidence-Based Medicine
Advantages of low dose polyethylene glycol + ascorbate split-dose colonoscopy preparation for colorectal screening
Caterina Palmonari, Nicolò Landini, Chiara Zanforlin, Michela Borghesi, Viviana Cifalà, Claudio Gregorio, Alessandro Pezzoli, Admena Rreshketa, Chiara Chiericati 
World J Gastrointest Oncol 18(7):117681. Published online Jul 15, 2026. doi: 10.4251/wjgo.117681
Systematic Reviews
Chinese herbal medicine for colorectal cancer: An overview of systematic reviews and evidence map
He-Ping Wang, Xiao-Yan Qin, Bo-Wen Xu, Tai-Cheng Lu, Rui-Ke Gao, Ming Lin, Jie Li 
World J Gastrointest Oncol 18(7):120031. Published online Jul 15, 2026. doi: 10.4251/wjgo.120031
Case Report
Duodenal signet-ring carcinoma arising in pyloric gland adenoma with RN7SL1/MUC6 upregulation and mitochondrial dysregulation: A case report
Xue Wen, Jie-Ying Qiu, Jun Li, Zheng-Rong Mao, Wei-Qiang Wu 
World J Gastrointest Oncol 18(7):117886. Published online Jul 15, 2026. doi: 10.4251/wjgo.117886
Long-term survival after combined hepatectomy and colectomy for ruptured combined hepatocellular-cholangiocarcinoma with direct colonic invasion: A case report
Chong-Wei Yang, Ri-Xin Zhang, Xiao-Lin Zheng, Ling Zhu, Zhi Zheng, Xin-Hua Wu 
World J Gastrointest Oncol 18(7):118212. Published online Jul 15, 2026. doi: 10.4251/wjgo.118212
Primary hepatic adenoid cystic carcinoma: A case report and review of literature
Han-Qi Xing, Tao-Ming Mo, Jie He 
World J Gastrointest Oncol 18(7):120564. Published online Jul 15, 2026. doi: 10.4251/wjgo.120564
Correspondence
Letter to the Editor: Comparable outcomes of sevoflurane vs propofol anesthesia in gastrectomy for gastric cancer
Pei-Wen Zhan, Tao Wang 
World J Gastrointest Oncol 18(7):116791. Published online Jul 15, 2026. doi: 10.4251/wjgo.116791
Letter to the Editor: Spinal IL-33/ST2 blockade for gallbladder carcinoma pain - balancing central analgesia with systemic tumor immune microenvironment risks
Yi Lu, Xin-Lei Zhou, Fan Chen 
World J Gastrointest Oncol 18(7):121633. Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.121633
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