Factors associated with complete clinical response after neoadjuvant therapy in locally advanced rectal cancer: A Mexican retrospective study

Figure 1 Flow diagram of the cohort and assessment of complete response. The diagram illustrates patient selection, neoadjuvant treatment, post-treatment response assessment, and clinical outcomes. It shows the proportion of patients achieving a complete response, including those with complete clinical response managed with a watch-and-wait strategy and those with pathological complete response confirmed after surgery, as well as the occurrence of local recurrence during follow-up. LARC: Locally advanced rectal cancer; MRI: Magnetic resonance imaging; cCR: Complete clinical response; pCR: Pathological complete response.

Figure 2 Kaplan-Meier curve for local recurrence. The graph shows the cumulative probability of local recurrence-free survival among complete responders (n = 20). Two local recurrence events were registered within the follow-up period (11 months and 15.9 months). The median recurrence-free survival was not reached due to the small number of events.