Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Oncol. Jul 15, 2026; 18(7): 116791
Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.116791
Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.116791
Letter to the Editor: Comparable outcomes of sevoflurane vs propofol anesthesia in gastrectomy for gastric cancer
Pei-Wen Zhan, Tao Wang, Laboratory of Protein Structure and Function, Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar 161006, Heilongjiang Province, China
Pei-Wen Zhan, Tao Wang, School of Medical Technology, Qiqihar Medical University, Qiqihar 161006, Heilongjiang Province, China
Author contributions: Zhan PW wrote the original draft; Wang T contributed to conceptualization, writing, reviewing, and editing.
Supported by the Natural Science Foundation of Heilongjiang Province, No. PL2025C097; the Education Department Foundation of Heilongjiang Province, No. 2024-KYYWF-0339; the Scientific Technology Project of Qiqihar City, No. LSFGG-2024099; the Qi-qihar Medical Institute Foundation, No. 2025-ZDPY-001; and the Construction Project of Dominant Characteristic Disciplines of Qiqihar Medical University, No. QYZDXK-003.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Tao Wang, PhD, Associate Professor, Laboratory of Protein Structure and Function, Institute of Medicine and Pharmacy, Qiqihar Medical University, No. 333 BuKui northern Street, Jianhua District, Qiqihar 161006, Heilongjiang Province, China.
Received: November 25, 2025
Revised: January 26, 2026
Accepted: March 9, 2026
Published online: July 15, 2026
Processing time: 223 Days and 19.5 Hours
Revised: January 26, 2026
Accepted: March 9, 2026
Published online: July 15, 2026
Processing time: 223 Days and 19.5 Hours
Core Tip
Core Tip: For gastric cancer patients undergoing radical gastrectomy, sevoflurane inhalation anesthesia and propofol-based total intravenous anesthesia yield comparable long-term survival outcomes and overall perioperative safety, with neither agent demonstrating obvious oncologic superiority. Therefore, anesthesia selection for these patients should be personalized based on their unique individual clinical characteristics and specific perioperative risk factors, making such tailored clinical choices the optimal anesthesia strategy for gastric cancer patients receiving radical gastrectomy.