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Contents Volume 18 Issue 2 February 26, 2026

Editorial

Mothers against decapentaplegic homolog 4 as a proteomic hub in vascular remodeling and residual cardiovascular risk

Davide Ramoni, Federico Carbone, Luca Liberale, Fabrizio Montecucco

World J Cardiol 18(2):117277. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.117277

Abstract (38) | Core Tip (41) | Full Article (HTML) (248) | Full Article (PDF)-395K (105) | Full Article with Cover (PDF)-886K (111) | Full Article (XML)-77K (29) | Audio-1008K (5) | Peer-Review Report-254K (12) | Answering Reviewers-122K (19) | Received: 12/03/2025 | Revised: 12/24/2025 | Accepted: 01/14/2026 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1092) | Similar Articles (1) | Timeline of Article Publication (3) | Article Quality Tracking (0) | Cite |

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Minireviews

Ryanodine receptor 2 mutations in catecholaminergic polymorphic ventricular tachycardia: From molecular mechanisms to precision medicine

Vaibhav Sharma

World J Cardiol 18(2):111032. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.111032

Abstract (47) | Core Tip (37) | Full Article (HTML) (286) | Figures (1-3) (35) | Tables (1-2) (36) | Full Article (PDF)-885K (155) | Full Article with Cover (PDF)-1370K (129) | Full Article (XML)-225K (14) | Audio-1878K (6) | Peer-Review Report-238K (18) | Answering Reviewers-220K (13) | Received: 06/20/2025 | Revised: 08/01/2025 | Accepted: 12/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1014) | Similar Articles (21) | Timeline of Article Publication (2) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Relationship between the oxidative stress biomarkers and coronary heart disease: Pathogenesis to therapeutic aspects

Aneeza Waris Hussain Rathore, Hira Naveed, Atif Nadeem, Aqib Ishaque, Sadia Iqbal, Uswah Ilyas, Tooba Arooj, Saira Rafaqat

World J Cardiol 18(2):113624. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.113624

Abstract (40) | Core Tip (48) | Full Article (HTML) (249) | Figures (1-1) (36) | Tables (1-3) (37) | Full Article (PDF)-878K (77) | Full Article with Cover (PDF)-1366K (29) | Full Article (XML)-243K (24) | Audio-124K (5) | Peer-Review Report-215K (23) | Answering Reviewers-261K (42) | Received: 08/29/2025 | Revised: 09/30/2025 | Accepted: 01/05/2026 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1102) | Similar Articles (307) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Residual risk in atherosclerotic cardiovascular disease after statin therapy: Clinical mechanisms and management strategies

Sze-Hua Tan, Jia-Lin Wu, Shu-Xiong Zhuo, Yi Zhang, Miao Wang

World J Cardiol 18(2):114960. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.114960

Abstract (43) | Core Tip (46) | Full Article (HTML) (601) | Figures (1-3) (35) | Tables (1-3) (51) | Full Article (PDF)-1866K (125) | Full Article with Cover (PDF)-2353K (576) | Full Article (XML)-230K (21) | Audio-588K (11) | Peer-Review Report-300K (23) | Answering Reviewers-56K (18) | Received: 10/03/2025 | Revised: 11/05/2025 | Accepted: 12/18/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (2135) | Similar Articles (46) | Timeline of Article Publication (3) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Case Control Study

Late left ventricular summit premature ventricular contractions elimination with new TactiFlex irrigation technology

Zefferino Palamà, Giuseppe Tricarico, Antonio Scarà, Antonio Gianluca Robles, Gabriele De Masi De Luca, Martina Nesti, Silvio Romano, Luigi Sciarra

World J Cardiol 18(2):111861. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.111861

Abstract (44) | Core Tip (35) | Full Article (HTML) (275) | Figures (1-3) (35) | Tables (1-1) (41) | Full Article (PDF)-2089K (64) | Full Article with Cover (PDF)-2579K (76) | Full Article (XML)-49K (21) | Audio-610K (8) | Peer-Review Report-237K (16) | Answering Reviewers-113K (17) | Supplementary Material-136K (11) | Received: 07/19/2025 | Revised: 08/01/2025 | Accepted: 01/06/2026 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1005) | Similar Articles (0) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Retrospective Cohort Study

Survival outcomes of elderly patients undergoing transcatheter aortic valve implantation after 3 years of follow-up

Abdulaziz Algethami, Salman Salem Alahmadi, Abdulrahman AlQahtani, Mohammed Balghith

World J Cardiol 18(2):114983. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.114983

Abstract (51) | Core Tip (30) | Full Article (HTML) (254) | Figures (1-1) (34) | Tables (1-5) (38) | Full Article (PDF)-512K (83) | Full Article with Cover (PDF)-1002K (136) | Full Article (XML)-75K (21) | Audio-466K (3) | Peer-Review Report-241K (19) | Answering Reviewers-64K (41) | Received: 10/03/2025 | Revised: 10/25/2025 | Accepted: 12/12/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1165) | Similar Articles (12) | Timeline of Article Publication (3) | Article Quality Tracking (0) | Cite |

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Efficacy of nitroglycerin vs labetalol in hypertensive emergency among patients with a history of coronary artery disease

Ahmed Jamal Chaudhary, Wasim Akbar Bhat, Affan Ul Haq, Haroon Ur Rashid, Irum Dad Khan, Mah Noor Dad Khan, Hafiz Muhammad Mubeen Nawaz, Sameer Ali, Muhammad Hamza Tariq

World J Cardiol 18(2):115528. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.115528

Abstract (64) | Core Tip (35) | Full Article (HTML) (342) | Figures (1-3) (56) | Tables (1-2) (47) | Full Article (PDF)-766K (79) | Full Article with Cover (PDF)-1256K (223) | Full Article (XML)-99K (20) | Audio-128K (12) | Peer-Review Report-200K (18) | Answering Reviewers-79K (18) | Received: 10/18/2025 | Revised: 11/01/2025 | Accepted: 12/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1255) | Similar Articles (50) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Retrospective Study

Five-year mean follow-up of NeoHexa sirolimus eluting coronary stent: A retrospective evaluation of long-term safety and efficacy

Vijay K Trehan, Safal Safal, Siddhant Trehan, Sanjeev Kathuria, Preeti S Vani

World J Cardiol 18(2):114636. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.114636

Abstract (92) | Core Tip (43) | Full Article (HTML) (176) | Figures (1-4) (43) | Tables (1-3) (42) | Full Article (PDF)-1128K (71) | Full Article with Cover (PDF)-1617K (62) | Full Article (XML)-98K (21) | Audio-484K (10) | Peer-Review Report-200K (26) | Answering Reviewers-86K (19) | Received: 09/29/2025 | Revised: 10/30/2025 | Accepted: 12/15/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1079) | Similar Articles (53) | Timeline of Article Publication (2) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Observational Study

Differences in cardiac output of patients undergoing trans-catheter aortic valve implantation according to their underlying rhythm

Muntaser Omari, Miray Ibrahim, Omran Abukhalaf, Ahmed Abdalwahab, Richard Edwards, Rajiv Das, Azfar Zaman, Mohamed Farag, Mohammad Alkhalil

World J Cardiol 18(2):110803. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.110803

Abstract (51) | Core Tip (33) | Full Article (HTML) (189) | Figures (1-2) (37) | Tables (1-3) (29) | Full Article (PDF)-621K (84) | Full Article with Cover (PDF)-1110K (104) | Full Article (XML)-140K (13) | Audio-184K (7) | Peer-Review Report-307K (20) | Answering Reviewers-358K (51) | Received: 06/15/2025 | Revised: 07/20/2025 | Accepted: 11/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (980) | Similar Articles (3) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Basic Study

Melatonin regulates Sirt1/Nrf2/GPX4 pathway to inhibit ferroptosis and alleviate myocardial injury caused by sepsis

Min Zeng, Qiong Li, Lin Li, Cheng-Fang Xiang, Yi-Jun Wang

World J Cardiol 18(2):113358. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.113358

Abstract (37) | Core Tip (42) | Full Article (HTML) (273) | Figures (1-7) (48) | Full Article (PDF)-6658K (106) | Full Article with Cover (PDF)-7148K (63) | Full Article (XML)-101K (20) | Audio-603K (10) | Peer-Review Report-246K (15) | Answering Reviewers-127K (18) | Received: 08/22/2025 | Revised: 09/28/2025 | Accepted: 11/28/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1214) | Similar Articles (143) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Systematic Reviews

Phenomenon of “de Winter” pattern, sign, or syndrome: A systematic scoping review and data analysis

Eman Elmenyar, Mohammad Adeeb Abbara, Zeina Al-Ghoul, Wael Al Mahmeed, Başar Cander, Ahmed Shaaban Abdelrahman, Hassan Al-Thani, Ayman El-Menyar

World J Cardiol 18(2):114561. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.114561

Abstract (57) | Core Tip (44) | Full Article (HTML) (338) | Figures (1-3) (36) | Tables (1-4) (47) | Full Article (PDF)-1028K (105) | Full Article with Cover (PDF)-1514K (236) | Full Article (XML)-223K (19) | Audio-181K (4) | Peer-Review Report-211K (18) | Answering Reviewers-56K (22) | Received: 09/22/2025 | Revised: 10/15/2025 | Accepted: 12/18/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1595) | Similar Articles (5) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Non-traditional risk factors for myocardial infarction in adults under forty: A systematic review of emerging trends

Tirath Patel, Muhammad Farhan, Nehal K Bhatt, Hewaz A Fatah, Joel J Peniel, Ved V Kaulgud, Tisimol Mathew, Aashita M Bapat, Waleed SS Harazeen, Abdullatif N Alatta, Ayoola Awosika

World J Cardiol 18(2):116172. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.116172

Abstract (60) | Core Tip (38) | Full Article (HTML) (443) | Figures (1-1) (36) | Tables (1-5) (43) | Full Article (PDF)-578K (73) | Full Article with Cover (PDF)-1065K (95) | Full Article (XML)-157K (19) | Audio-2125K (6) | Peer-Review Report-227K (37) | Answering Reviewers-54K (20) | Received: 11/04/2025 | Revised: 11/14/2025 | Accepted: 01/04/2026 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1198) | Similar Articles (1) | Timeline of Article Publication (0) | Article Quality Tracking (1) | Cite |

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Meta-Analysis

Comparative efficacy and safety of chlorthalidone vs hydrochlorothiazide in hypertension management: A systematic review and meta-analysis

Usha Kumari, Manaswini Kaka, Fakhar Abbas, Amar Rai, Sanjana Kumari, Hakim Ullah Wazir, Salim Surani

World J Cardiol 18(2):112956. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.112956

Abstract (49) | Core Tip (37) | Full Article (HTML) (378) | Figures (1-10) (40) | Full Article (PDF)-2388K (166) | Full Article with Cover (PDF)-2879K (18) | Full Article (XML)-87K (19) | Audio-586K (6) | Peer-Review Report-191K (15) | Answering Reviewers-72K (19) | Received: 08/10/2025 | Revised: 10/01/2025 | Accepted: 12/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1556) | Similar Articles (86) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Oral anticoagulant therapy and outcomes in new-onset atrial fibrillation during acute myocardial infarction: A systematic review and meta-analysis

Kristina G Pereverzeva, Ayoub Glenza, Sergey S Yakushin

World J Cardiol 18(2):114265. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.114265

Abstract (43) | Core Tip (40) | Full Article (HTML) (321) | Figures (1-3) (36) | Tables (1-1) (30) | Full Article (PDF)-2011K (91) | Full Article with Cover (PDF)-2499K (35) | Full Article (XML)-150K (17) | Audio-1581K (10) | Peer-Review Report-214K (20) | Answering Reviewers-167K (23) | Received: 09/14/2025 | Revised: 10/02/2025 | Accepted: 12/10/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (1052) | Similar Articles (37) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Letter to the Editor

Frailty first: Rethinking invasive strategies for elderly patients with non-ST-elevation myocardial infarction

Nikias Milaras, Konstantinos Toutouzas, Skevos Sideris

World J Cardiol 18(2):114706. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.114706

Abstract (47) | Core Tip (32) | Full Article (HTML) (177) | Full Article (PDF)-328K (53) | Full Article with Cover (PDF)-822K (56) | Full Article (XML)-23K (19) | Audio-870K (3) | Peer-Review Report-239K (18) | Answering Reviewers-576K (18) | Received: 09/25/2025 | Revised: 11/02/2025 | Accepted: 12/24/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (720) | Similar Articles (32) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Frailty in elderly patients with non-ST elevation myocardial infarction: Balancing the risks and benefits of percutaneous coronary intervention

Hussam Ali, Flavio Airoldi, Riccardo Cappato

World J Cardiol 18(2):115016. Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.115016

Abstract (39) | Core Tip (36) | Full Article (HTML) (169) | Full Article (PDF)-369K (65) | Full Article with Cover (PDF)-860K (63) | Full Article (XML)-40K (14) | Audio-1460K (10) | Peer-Review Report-262K (15) | Answering Reviewers-101K (20) | Received: 10/05/2025 | Revised: 11/07/2025 | Accepted: 12/22/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (777) | Similar Articles (70) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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