Copyright
©The Author(s) 2026.
World J Cardiol. Feb 26, 2026; 18(2): 112956
Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.112956
Published online Feb 26, 2026. doi: 10.4330/wjc.v18.i2.112956
Figure 1 Preferred Reporting Items for Systematic Reviews and Meta-Analysis flowchart representing the selection process inclusion of studies.
Adapted from Cochrane Methods Bias[20].
Figure 2 Forest plot comparing the effect of chlorthalidone and hydrochlorothiazide on systolic blood pressure reduction.
CTD: Chlorthidone; HCTZ: Hydrochlorthiazide.
Figure 3 Forest plot comparing the effect of chlorthalidone and hydrochlorothiazide on diastolic blood pressure reduction.
CTD: Chlorthidone; HCTZ: Hydrochlorthiazide.
Figure 4 Forest plot comparing the effect of chlorthalidone and hydrochlorothiazide on day and nighttime blood pressure control.
CTD: Chlorthidone; HCTZ: Hydrochlorthiazide.
Figure 5 Forest plot comparing the effect of chlorthalidone and hydrochlorothiazide on blood pressure control among different races.
CTD: Chlorthidone; HCTZ: Hydrochlorthiazide.
Figure 6 Forest plot comparing the risk of myocardial infarction between the chlorthalidone and hydrochlorothiazide group.
CTD: Chlorthidone; HCTZ: Hydrochlorthiazide; RR: Relative risk.
Figure 7 Forest plot comparing the risk of heart failure and hospitalization between the chlorthalidone and hydrochlorothiazide groups.
CTD: Chlorthidone; HCTZ: Hydrochlorthiazide; RR: Relative risk.
Figure 8 Forest plot comparing the risk of hypokalemia between the chlorthalidone and hydrochlorothiazide groups.
CTD: Chlorthidone; HCTZ: Hydrochlorthiazide; RR: Relative risk.
Figure 9 Forest plot comparing the risk of stroke between the chlorthalidone and hydrochlorothiazide groups.
CTD: Chlorthidone; HCTZ: Hydrochlorthiazide; RR: Relative risk.
Figure 10 Forest plot comparing the risk of all-cause mortality between chlorthalidone and hydrochlorothiazide groups.
CTD: Chlorthidone; HCTZ: Hydrochlorthiazide; RR: Relative risk.
- Citation: Kumari U, Kaka M, Abbas F, Rai A, Kumari S, Wazir HU, Surani S. Comparative efficacy and safety of chlorthalidone vs hydrochlorothiazide in hypertension management: A systematic review and meta-analysis. World J Cardiol 2026; 18(2): 112956
- URL: https://www.wjgnet.com/1949-8462/full/v18/i2/112956.htm
- DOI: https://dx.doi.org/10.4330/wjc.v18.i2.112956
