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Contents Volume 17 Issue 9 September 26, 2025

Review

Neural crest-derived mesenchymal stem cells: Fates and perspectives

Yi-Lin He, Si-Jia Chen, Deng-Sheng Xia, Wen-Peng Song

World J Stem Cells 17(9):107689. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.107689

Abstract (196) | Core Tip (211) | Full Article (HTML) (1178) | Figures (1-1) (118) | Tables (1-4) (364) | Full Article (PDF)-1659K (189) | Full Article with Cover (PDF)-2004K (153) | Full Article (XML)-359K (65) | Audio-1644K (55) | Received: 03/27/2025 | Revised: 04/25/2025 | Accepted: 08/08/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (18) | Cite | (66) | (69) | (0) | (0) | (0) | (22) | (4047) | (5) | Open

Stem cell-based cartilage regeneration: Biological strategies, engineering innovations, and clinical translation

Bo Cong, Feng-Hua Zhang, Hai-Guang Zhang

World J Stem Cells 17(9):108523. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.108523

Abstract (243) | Core Tip (184) | Full Article (HTML) (1541) | Figures (1-2) (130) | Tables (1-2) (148) | Full Article (PDF)-1838K (203) | Full Article with Cover (PDF)-2183K (133) | Full Article (XML)-213K (80) | Audio-882K (86) | Received: 04/16/2025 | Revised: 05/27/2025 | Accepted: 07/08/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (3) | Cite | (69) | (77) | (0) | (0) | (0) | (1) | (1) | (5461) | (11) | Open

HOX and MEINOX in cellular plasticity, fibrosis, and cancer

Mustafa Keleş, Aysen Gunel-Ozcan

World J Stem Cells 17(9):109102. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.109102

Abstract (153) | Core Tip (166) | Full Article (HTML) (855) | Figures (1-4) (146) | Tables (1-8) (173) | Full Article (PDF)-3940K (158) | Full Article with Cover (PDF)-4285K (95) | Full Article (XML)-505K (85) | Audio-281K (44) | Received: 04/29/2025 | Revised: 06/16/2025 | Accepted: 08/18/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (308) | Cite | (71) | (68) | (0) | (0) | (0) | (3283) | (1) | Open

Minireviews

Dual role and clinical application of extracellular vesicles in acute respiratory distress syndrome: Mechanism analysis and translational challenges

Yi-Fu Tie, Han Liu, Tong Zhang, Tian-Wei Meng, Qun Liang

World J Stem Cells 17(9):108657. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.108657

Abstract (165) | Core Tip (150) | Full Article (HTML) (593) | Figures (1-2) (139) | Tables (1-1) (139) | Full Article (PDF)-3728K (112) | Full Article with Cover (PDF)-4070K (73) | Full Article (XML)-167K (64) | Audio-534K (42) | Received: 04/19/2025 | Revised: 05/14/2025 | Accepted: 08/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (88) | Cite | (55) | (66) | (0) | (0) | (0) | (3066) | (3) | Open

Post-translational modifications in osteogenic differentiation of oral-derived stem cells: Mechanisms and clinical implications

Zhuo-Jin Shi, Wei Liu

World J Stem Cells 17(9):109662. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.109662

Abstract (174) | Core Tip (146) | Full Article (HTML) (782) | Figures (1-1) (154) | Tables (1-3) (161) | Full Article (PDF)-742K (132) | Full Article with Cover (PDF)-1086K (110) | Full Article (XML)-226K (76) | Audio-1379K (49) | Received: 05/17/2025 | Revised: 06/22/2025 | Accepted: 08/13/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (4) | Cite | (62) | (61) | (0) | (0) | (0) | (4128) | (2) | Open

Retrospective Study

Expression of cancer stem cell markers and their prognostic significance in stage IIIA non-small cell lung cancer

Tao Lin, Si-Cong Jiang, Xian-Ming He, Wen-Zhen Xu, Cai-Jin Jin, You-Dan Guo

World J Stem Cells 17(9):106381. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.106381

Abstract (181) | Core Tip (169) | Full Article (HTML) (611) | Figures (1-2) (116) | Tables (1-2) (126) | Full Article (PDF)-815K (108) | Full Article with Cover (PDF)-1161K (78) | Full Article (XML)-114K (81) | Audio-84K (48) | Received: 03/20/2025 | Revised: 05/16/2025 | Accepted: 08/04/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (0) | Cite | (59) | (57) | (0) | (0) | (0) | (2998) | (2) | Open

Randomized Controlled Trial

Combined mesenchymal and neural stem cell therapy enhances neurological recovery in cerebral infarction

Ting Yang, Hui Yu, Dong Han, Zheng Xie

World J Stem Cells 17(9):110663. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.110663

Abstract (177) | Core Tip (205) | Full Article (HTML) (845) | Figures (1-1) (114) | Tables (1-4) (123) | Full Article (PDF)-920K (123) | Full Article with Cover (PDF)-1266K (107) | Full Article (XML)-90K (67) | Audio-593K (43) | Received: 06/13/2025 | Revised: 07/22/2025 | Accepted: 09/04/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (228) | Cite | (66) | (58) | (0) | (0) | (0) | (3849) | (5) | Open

Basic Study

Quercetin pretreated umbilical cord mesenchymal stem cells alleviate inflammatory bowel disease via IL-10 /Janus kinase 2/STAT3 signaling

Meng-Yue Shi, Lian Liu, Fu-Yuan Yang

World J Stem Cells 17(9):105896. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.105896

Abstract (165) | Core Tip (155) | Full Article (HTML) (702) | Figures (1-7) (132) | Tables (1-4) (135) | Full Article (PDF)-16218K (107) | Full Article with Cover (PDF)-16564K (89) | Full Article (XML)-136K (72) | Audio-233K (64) | Received: 02/09/2025 | Revised: 04/07/2025 | Accepted: 08/04/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (7) | Cite | (66) | (77) | (0) | (0) | (0) | (28) | (4977) | (1) | Open

Bone marrow mesenchymal stem cell-derived exosomal lactate dehydrogenase A promotes tendon-bone healing via histone lactylation-mediated cartilage regeneration

Ting Zhang, Qing Huang, Kai-Feng Gan

World J Stem Cells 17(9):106282. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.106282

Abstract (178) | Core Tip (175) | Full Article (HTML) (617) | Figures (1-5) (132) | Tables (1-2) (124) | Full Article (PDF)-6246K (161) | Full Article with Cover (PDF)-6589K (102) | Full Article (XML)-107K (63) | Audio-68K (84) | Supplementary Material-303K (63) | Received: 02/26/2025 | Revised: 03/27/2025 | Accepted: 09/05/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (2) | Cite | (67) | (62) | (0) | (0) | (0) | (1) | (3526) | (6) | Open

Wumei Pills enhance intestinal stem cell - mediated repair in chemotherapy-induced mucositis via Lactobacillus reuteri - dependent modulation of the gut microbiota

Dong-Xue Lu, Zi-Xuan Wang, Xi-Min Liu, Hua Wu, Li-Jiang Ji, Jing Yan

World J Stem Cells 17(9):107025. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.107025

Abstract (177) | Core Tip (173) | Full Article (HTML) (700) | Figures (1-7) (139) | Tables (1-1) (121) | Full Article (PDF)-8376K (119) | Full Article with Cover (PDF)-8721K (82) | Full Article (XML)-113K (65) | Audio-528K (45) | Received: 03/15/2025 | Revised: 05/10/2025 | Accepted: 08/25/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (2) | Cite | (59) | (82) | (0) | (0) | (0) | (35) | (4607) | (3) | Open

Efficacy and safety of umbilical cord-derived mesenchymal stem cell-conditioned media for preventing and treating skin aging

Hyunjun Ahn, Ho-Seong Han, Kye-Ho Lee

World J Stem Cells 17(9):108049. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.108049

Abstract (205) | Core Tip (191) | Full Article (HTML) (1463) | Figures (1-4) (137) | Tables (1-1) (174) | Full Article (PDF)-12509K (180) | Full Article with Cover (PDF)-12853K (102) | Full Article (XML)-114K (65) | Audio-822K (72) | Supplementary Material-463K (72) | Received: 04/09/2025 | Revised: 06/12/2025 | Accepted: 08/29/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (17) | Cite | (61) | (62) | (0) | (0) | (0) | (5944) | (1) | Open

Exercise combined with induced pluripotent stem cells enhances the Wnt1-Lmx1a loop in the midbrain of Parkinsonian mice to alleviate Parkinsonian symptoms

Xing Jiang, Zhi-Min Lu, Qing-Lu Wang, Ying Luo, Jie Zhang

World J Stem Cells 17(9):109330. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.109330

Abstract (160) | Core Tip (143) | Full Article (HTML) (595) | Figures (1-5) (116) | Tables (1-1) (111) | Full Article (PDF)-5590K (120) | Full Article with Cover (PDF)-5933K (77) | Full Article (XML)-169K (83) | Audio-1583K (46) | Received: 05/08/2025 | Revised: 06/18/2025 | Accepted: 08/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (86) | Cite | (60) | (75) | (0) | (0) | (0) | (22) | (1) | (3165) | (3) | Open

Exploring the critical therapeutic window: Dose-frequency optimization of human umbilical cord mesenchymal stem cells for preclinical asthma treatment

Qiong-Hua Chen, Jing-Yang Zheng, Yu-Qin Zhu, Jun-Yao Zhang, Chun-Yan Lin, Xue-E Zhuang, Jing Cheng, Xiao-Yi Huang

World J Stem Cells 17(9):109715. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.109715

Abstract (176) | Core Tip (163) | Full Article (HTML) (548) | Figures (1-6) (120) | Full Article (PDF)-4940K (105) | Full Article with Cover (PDF)-5285K (103) | Full Article (XML)-77K (74) | Audio-1018K (43) | Received: 05/19/2025 | Revised: 06/17/2025 | Accepted: 08/29/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (55) | Cite | (68) | (56) | (0) | (0) | (0) | (30) | (3239) | Open

Letter to the Editor

Human umbilical cord mesenchymal stromal cell-derived extracellular vesicles alleviate radiation induced pulmonary fibrosis

Jing-Jing Wang, Hong-Jie Xu

World J Stem Cells 17(9):111341. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.111341

Abstract (191) | Core Tip (153) | Full Article (HTML) (654) | Full Article (PDF)-402K (122) | Full Article with Cover (PDF)-749K (87) | Full Article (XML)-69K (89) | Audio-884K (65) | Received: 07/03/2025 | Revised: 07/21/2025 | Accepted: 09/03/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (47) | Cite | (62) | (78) | (0) | (0) | (0) | (27) | (2837) | Open

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