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Contents Volume 17 Issue 9 September 26, 2025

Review

Neural crest-derived mesenchymal stem cells: Fates and perspectives

Yi-Lin He, Si-Jia Chen, Deng-Sheng Xia, Wen-Peng Song

World J Stem Cells 17(9):107689. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.107689

Abstract (160) | Core Tip (172) | Full Article (HTML) (921) | Figures (1-1) (101) | Tables (1-4) (281) | Full Article (PDF)-1659K (177) | Full Article with Cover (PDF)-2004K (116) | Full Article (XML)-359K (48) | Audio-1644K (48) | Received: 03/27/2025 | Revised: 04/25/2025 | Accepted: 08/08/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (18) | Timeline of Article Publication (0) | Cite | (56) | (62) | (0) | (0) | (0) | (15) | (1644) | (5) | Open

Stem cell-based cartilage regeneration: Biological strategies, engineering innovations, and clinical translation

Bo Cong, Feng-Hua Zhang, Hai-Guang Zhang

World J Stem Cells 17(9):108523. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.108523

Abstract (187) | Core Tip (151) | Full Article (HTML) (1319) | Figures (1-2) (112) | Tables (1-2) (130) | Full Article (PDF)-1838K (187) | Full Article with Cover (PDF)-2183K (108) | Full Article (XML)-213K (61) | Audio-882K (84) | Received: 04/16/2025 | Revised: 05/27/2025 | Accepted: 07/08/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (3) | Timeline of Article Publication (0) | Cite | (53) | (66) | (0) | (0) | (0) | (1) | (1) | (1917) | (10) | Open

HOX and MEINOX in cellular plasticity, fibrosis, and cancer

Mustafa Keleş, Aysen Gunel-Ozcan

World J Stem Cells 17(9):109102. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.109102

Abstract (127) | Core Tip (138) | Full Article (HTML) (703) | Figures (1-4) (126) | Tables (1-8) (149) | Full Article (PDF)-3940K (144) | Full Article with Cover (PDF)-4285K (81) | Full Article (XML)-505K (70) | Audio-281K (40) | Received: 04/29/2025 | Revised: 06/16/2025 | Accepted: 08/18/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (307) | Timeline of Article Publication (0) | Cite | (57) | (55) | (0) | (0) | (0) | (1273) | (1) | Open

Minireviews

Dual role and clinical application of extracellular vesicles in acute respiratory distress syndrome: Mechanism analysis and translational challenges

Yi-Fu Tie, Han Liu, Tong Zhang, Tian-Wei Meng, Qun Liang

World J Stem Cells 17(9):108657. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.108657

Abstract (136) | Core Tip (122) | Full Article (HTML) (478) | Figures (1-2) (119) | Tables (1-1) (115) | Full Article (PDF)-3728K (96) | Full Article with Cover (PDF)-4070K (57) | Full Article (XML)-167K (46) | Audio-534K (40) | Received: 04/19/2025 | Revised: 05/14/2025 | Accepted: 08/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (86) | Timeline of Article Publication (0) | Cite | (44) | (52) | (0) | (0) | (0) | (911) | (2) | Open

Post-translational modifications in osteogenic differentiation of oral-derived stem cells: Mechanisms and clinical implications

Zhuo-Jin Shi, Wei Liu

World J Stem Cells 17(9):109662. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.109662

Abstract (145) | Core Tip (127) | Full Article (HTML) (599) | Figures (1-1) (135) | Tables (1-3) (139) | Full Article (PDF)-742K (119) | Full Article with Cover (PDF)-1086K (87) | Full Article (XML)-226K (58) | Audio-1379K (47) | Received: 05/17/2025 | Revised: 06/22/2025 | Accepted: 08/13/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (4) | Timeline of Article Publication (11) | Cite | (50) | (49) | (0) | (0) | (0) | (1137) | (2) | Open

Retrospective Study

Expression of cancer stem cell markers and their prognostic significance in stage IIIA non-small cell lung cancer

Tao Lin, Si-Cong Jiang, Xian-Ming He, Wen-Zhen Xu, Cai-Jin Jin, You-Dan Guo

World J Stem Cells 17(9):106381. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.106381

Abstract (154) | Core Tip (145) | Full Article (HTML) (490) | Figures (1-2) (101) | Tables (1-2) (106) | Full Article (PDF)-815K (93) | Full Article with Cover (PDF)-1161K (62) | Full Article (XML)-114K (64) | Audio-84K (47) | Received: 03/20/2025 | Revised: 05/16/2025 | Accepted: 08/04/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (0) | Timeline of Article Publication (1) | Cite | (48) | (47) | (0) | (0) | (0) | (916) | (2) | Open

Randomized Controlled Trial

Combined mesenchymal and neural stem cell therapy enhances neurological recovery in cerebral infarction

Ting Yang, Hui Yu, Dong Han, Zheng Xie

World J Stem Cells 17(9):110663. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.110663

Abstract (150) | Core Tip (173) | Full Article (HTML) (696) | Figures (1-1) (97) | Tables (1-4) (99) | Full Article (PDF)-920K (105) | Full Article with Cover (PDF)-1266K (79) | Full Article (XML)-90K (49) | Audio-593K (38) | Received: 06/13/2025 | Revised: 07/22/2025 | Accepted: 09/04/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (226) | Timeline of Article Publication (1) | Cite | (50) | (46) | (0) | (0) | (0) | (1125) | (4) | Open

Basic Study

Quercetin pretreated umbilical cord mesenchymal stem cells alleviate inflammatory bowel disease via IL-10 /Janus kinase 2/STAT3 signaling

Meng-Yue Shi, Lian Liu, Fu-Yuan Yang

World J Stem Cells 17(9):105896. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.105896

Abstract (135) | Core Tip (126) | Full Article (HTML) (585) | Figures (1-7) (109) | Tables (1-4) (115) | Full Article (PDF)-16218K (87) | Full Article with Cover (PDF)-16564K (75) | Full Article (XML)-136K (58) | Audio-233K (62) | Received: 02/09/2025 | Revised: 04/07/2025 | Accepted: 08/04/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (7) | Timeline of Article Publication (2) | Cite | (57) | (64) | (0) | (0) | (0) | (18) | (1029) | Open

Bone marrow mesenchymal stem cell-derived exosomal lactate dehydrogenase A promotes tendon-bone healing via histone lactylation-mediated cartilage regeneration

Ting Zhang, Qing Huang, Kai-Feng Gan

World J Stem Cells 17(9):106282. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.106282

Abstract (147) | Core Tip (148) | Full Article (HTML) (506) | Figures (1-5) (109) | Tables (1-2) (107) | Full Article (PDF)-6246K (141) | Full Article with Cover (PDF)-6589K (93) | Full Article (XML)-107K (47) | Audio-68K (81) | Supplementary Material-303K (53) | Received: 02/26/2025 | Revised: 03/27/2025 | Accepted: 09/05/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (2) | Timeline of Article Publication (2) | Cite | (54) | (46) | (0) | (0) | (0) | (1) | (1003) | (5) | Open

Wumei Pills enhance intestinal stem cell - mediated repair in chemotherapy-induced mucositis via Lactobacillus reuteri - dependent modulation of the gut microbiota

Dong-Xue Lu, Zi-Xuan Wang, Xi-Min Liu, Hua Wu, Li-Jiang Ji, Jing Yan

World J Stem Cells 17(9):107025. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.107025

Abstract (150) | Core Tip (143) | Full Article (HTML) (574) | Figures (1-7) (117) | Tables (1-1) (100) | Full Article (PDF)-8376K (103) | Full Article with Cover (PDF)-8721K (71) | Full Article (XML)-113K (50) | Audio-528K (44) | Received: 03/15/2025 | Revised: 05/10/2025 | Accepted: 08/25/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (2) | Timeline of Article Publication (0) | Cite | (47) | (67) | (0) | (0) | (0) | (30) | (1015) | (2) | Open

Efficacy and safety of umbilical cord-derived mesenchymal stem cell-conditioned media for preventing and treating skin aging

Hyunjun Ahn, Ho-Seong Han, Kye-Ho Lee

World J Stem Cells 17(9):108049. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.108049

Abstract (174) | Core Tip (166) | Full Article (HTML) (1204) | Figures (1-4) (116) | Tables (1-1) (138) | Full Article (PDF)-12509K (149) | Full Article with Cover (PDF)-12853K (87) | Full Article (XML)-114K (52) | Audio-822K (67) | Supplementary Material-463K (49) | Received: 04/09/2025 | Revised: 06/12/2025 | Accepted: 08/29/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (17) | Timeline of Article Publication (4) | Cite | (51) | (52) | (0) | (0) | (0) | (1746) | (1) | Open

Exercise combined with induced pluripotent stem cells enhances the Wnt1-Lmx1a loop in the midbrain of Parkinsonian mice to alleviate Parkinsonian symptoms

Xing Jiang, Zhi-Min Lu, Qing-Lu Wang, Ying Luo, Jie Zhang

World J Stem Cells 17(9):109330. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.109330

Abstract (136) | Core Tip (122) | Full Article (HTML) (495) | Figures (1-5) (98) | Tables (1-1) (97) | Full Article (PDF)-5590K (106) | Full Article with Cover (PDF)-5933K (65) | Full Article (XML)-169K (63) | Audio-1583K (43) | Received: 05/08/2025 | Revised: 06/18/2025 | Accepted: 08/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (86) | Timeline of Article Publication (0) | Cite | (53) | (68) | (0) | (0) | (0) | (16) | (1) | (924) | (3) | Open

Exploring the critical therapeutic window: Dose-frequency optimization of human umbilical cord mesenchymal stem cells for preclinical asthma treatment

Qiong-Hua Chen, Jing-Yang Zheng, Yu-Qin Zhu, Jun-Yao Zhang, Chun-Yan Lin, Xue-E Zhuang, Jing Cheng, Xiao-Yi Huang

World J Stem Cells 17(9):109715. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.109715

Abstract (143) | Core Tip (136) | Full Article (HTML) (435) | Figures (1-6) (100) | Full Article (PDF)-4940K (91) | Full Article with Cover (PDF)-5285K (81) | Full Article (XML)-77K (66) | Audio-1018K (41) | Received: 05/19/2025 | Revised: 06/17/2025 | Accepted: 08/29/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (53) | Timeline of Article Publication (0) | Cite | (59) | (47) | (0) | (0) | (0) | (26) | (773) | Open

Letter to the Editor

Human umbilical cord mesenchymal stromal cell-derived extracellular vesicles alleviate radiation induced pulmonary fibrosis

Jing-Jing Wang, Hong-Jie Xu

World J Stem Cells 17(9):111341. Published online Sep 26, 2025. doi: 10.4252/wjsc.v17.i9.111341

Abstract (159) | Core Tip (124) | Full Article (HTML) (522) | Full Article (PDF)-402K (110) | Full Article with Cover (PDF)-749K (72) | Full Article (XML)-69K (70) | Audio-884K (64) | Received: 07/03/2025 | Revised: 07/21/2025 | Accepted: 09/03/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (46) | Timeline of Article Publication (2) | Cite | (50) | (62) | (0) | (0) | (0) | (21) | (774) | Open

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