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Contents Volume 17 Issue 3 March 15, 2026

Editorial

Molecular insights into hyperglycemia-associated coronary heart disease: From glycemic variability and heart rate dynamics to long noncoding RNAs

Shilpy Singh, Varun Kumar Sharma, Dharmsheel Shrivastav

World J Diabetes 17(3):115033. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.115033

Abstract (31) | Core Tip (47) | Full Article (HTML) (242) | Figures (1-1) (28) | Full Article (PDF)-1982K (27) | Full Article with Cover (PDF)-2237K (17) | Full Article (XML)-52K (13) | Audio-259K (3) | Peer-Review Report-458K (12) | Answering Reviewers-39K (12) | Received: 10/05/2025 | Revised: 11/20/2025 | Accepted: 12/17/2025 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (870) | Similar Articles (2) | Timeline of Article Publication (1) | Authors Evaluation (3) | Article Quality Tracking (0) | Cite |

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Review

Mitochondrial autophagy in diabetes-related cognitive decline and skin ulcers: Mechanistic insights and therapeutic implications

Xing Chen, Ling-Ling Zhang, Yu Zhou, Dong-Xiang Dong, Xiao-Ying Qian

World J Diabetes 17(3):112177. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.112177

Abstract (59) | Core Tip (64) | Full Article (HTML) (207) | Figures (1-5) (34) | Full Article (PDF)-9261K (27) | Full Article with Cover (PDF)-9515K (13) | Full Article (XML)-403K (15) | Audio-207K (3) | Peer-Review Report-263K (14) | Answering Reviewers-256K (12) | Supplementary Material-2358K (15) | Received: 07/29/2025 | Revised: 09/18/2025 | Accepted: 01/12/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (811) | Similar Articles (1) | Timeline of Article Publication (2) | Article Quality Tracking (1) | Cite |

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Circulating microbiome and its clinical implications in diabetes mellitus: Mechanistic insights and therapeutic perspectives

Dinakaran Vasudevan

World J Diabetes 17(3):113843. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.113843

Abstract (34) | Core Tip (46) | Full Article (HTML) (150) | Figures (1-10) (34) | Tables (1-3) (32) | Full Article (PDF)-7689K (21) | Full Article with Cover (PDF)-7934K (18) | Full Article (XML)-515K (17) | Audio-1492K (4) | Peer-Review Report-204K (12) | Answering Reviewers-268K (15) | Received: 09/04/2025 | Revised: 12/02/2025 | Accepted: 01/14/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (837) | Similar Articles (143) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Beyond glycemia: The influence of systemic inflammation, lipids, and the gut-retina axis in diabetic retinopathy

Marco Zeppieri, Alessandro Drigo, Matteo Capobianco, Federico Visalli, Francesco Cappellani, Mutali Musa, Rosa Giglio, Daniele Tognetto, Marieme Khouyyi, Caterina Gagliano, Fabiana D’Esposito, Leandro Inferrera

World J Diabetes 17(3):114603. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.114603

Abstract (72) | Core Tip (75) | Full Article (HTML) (257) | Figures (1-4) (34) | Tables (1-1) (33) | Full Article (PDF)-1340K (30) | Full Article with Cover (PDF)-1591K (15) | Full Article (XML)-229K (16) | Audio-339K (3) | Peer-Review Report-238K (15) | Answering Reviewers-839K (21) | Received: 09/23/2025 | Revised: 10/20/2025 | Accepted: 12/17/2025 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (858) | Similar Articles (70) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Dysfunction of the brain-gut axis in diabetic gastroparesis: Underlying mechanisms and therapeutic strategies

Wen-Long Jiang, Xu-Yang Hu, Hong-Xin Zheng, Ming-Hua Nan, Li-Zhe Liang, Tian-Xu Wang, Jing-Lin Li, Chang-Chuan Bai

World J Diabetes 17(3):119126. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.119126

Abstract (37) | Core Tip (48) | Full Article (HTML) (353) | Figures (1-2) (29) | Tables (1-2) (31) | Full Article (PDF)-1525K (42) | Full Article with Cover (PDF)-1777K (20) | Full Article (XML)-383K (24) | Audio-484K (3) | Peer-Review Report-482K (11) | Answering Reviewers-77K (16) | Supplementary Material-810K (17) | Received: 01/19/2026 | Revised: 02/13/2026 | Accepted: 03/09/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1186) | Similar Articles (12) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Minireviews

Metabolic basis of sudden sensorineural hearing loss in diabetes mellitus: From epidemiological association to mechanistic understanding

Shu-Fen Li, Shu-Yue Yu, Yi-Yuan Liu, Shu-Cai Fu, Yuan-Ping Xiong

World J Diabetes 17(3):115180. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.115180

Abstract (120) | Core Tip (35) | Full Article (HTML) (153) | Figures (1-1) (34) | Tables (1-1) (29) | Full Article (PDF)-610K (32) | Full Article with Cover (PDF)-889K (17) | Full Article (XML)-147K (15) | Audio-804K (2) | Peer-Review Report-288K (16) | Answering Reviewers-335K (15) | Received: 10/10/2025 | Revised: 11/22/2025 | Accepted: 01/07/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (657) | Similar Articles (146) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Clinical Trials Study

Compound danshen dripping pills for diabetic retinopathy in patients with type 2 diabetes: A superiority, randomized controlled trial

Xue-Dong An, Guo-Liang Zhang, Yue-Hong Zhang, De Jin, Hang-Yu Ji, Li-Juan Wei, Ya-Lin He, Yan-Lin Zheng, Du-Jun Li, Xing-Wei Wu, Yuan-Bin Li, Jian Zhou, Shao-Jian Tan, Ming-Chang Zhang, Ke Fan, Shan Lu, Jing-Sheng Yu, Yu-Liang Wang, Shao-Jun Chen, Qiu-Hong Liu, Ming Jin, Lie Wu, Feng-Mei Lian, Xiao-Lin Tong

World J Diabetes 17(3):114002. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.114002

Abstract (37) | Core Tip (36) | Full Article (HTML) (270) | Figures (1-3) (29) | Tables (1-8) (40) | Full Article (PDF)-1612K (47) | Full Article with Cover (PDF)-1888K (19) | Full Article (XML)-137K (16) | Audio-162K (3) | Peer-Review Report-252K (16) | Answering Reviewers-195K (21) | Supplementary Material-2324K (21) | Received: 09/08/2025 | Revised: 10/20/2025 | Accepted: 01/04/2026 | RCA | CrossRef | Google Scholar | Times Cited (1) | Total Visits (1272) | Similar Articles (67) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Observational Study

Associations of black coffee and black coffee supplemented with milk with diabetes in China: A community-based cross-sectional study

Yi Zeng, Pei-Yi Li, Zhi Chen, Nan-Fang Yao, Hong Ye, Zi-Hao Gui, Hua-Lan Chen, Lan Liu, Heng Wan, Jie Shen

World J Diabetes 17(3):115304. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.115304

Abstract (32) | Core Tip (34) | Full Article (HTML) (172) | Figures (1-1) (32) | Tables (1-5) (31) | Full Article (PDF)-533K (30) | Full Article with Cover (PDF)-812K (13) | Full Article (XML)-126K (15) | Audio-505K (3) | Peer-Review Report-301K (15) | Answering Reviewers-281K (14) | Supplementary Material-79K (19) | Received: 10/14/2025 | Revised: 11/24/2025 | Accepted: 02/04/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (972) | Similar Articles (5) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Prevalence and clinical characteristics of diabetic retinopathy in patients newly diagnosed with ketosis-onset diabetes: A real-world study

Man-Rong Xu, Meng-Han Li, Jun-Wei Wang, Ya-Wen Zhang, Jun-Xi Lu, Jiang-Feng Ke, Lian-Xi Li

World J Diabetes 17(3):115465. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.115465

Abstract (44) | Core Tip (40) | Full Article (HTML) (139) | Figures (1-3) (34) | Tables (1-2) (34) | Full Article (PDF)-853K (36) | Full Article with Cover (PDF)-1131K (18) | Full Article (XML)-120K (16) | Audio-1145K (5) | Peer-Review Report-313K (21) | Answering Reviewers-197K (20) | Received: 10/17/2025 | Revised: 11/23/2025 | Accepted: 01/06/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1058) | Similar Articles (68) | Timeline of Article Publication (9) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Association between gestational diabetes mellitus and dyslipidemia in the Buea Health District, Cameroon

Ebot Walter Ojong, Nicole Nanyongo Nakondo, Abdel Jelil Njouendou

World J Diabetes 17(3):115566. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.115566

Abstract (34) | Core Tip (39) | Full Article (HTML) (116) | Figures (1-1) (26) | Tables (1-9) (26) | Full Article (PDF)-593K (28) | Full Article with Cover (PDF)-869K (11) | Full Article (XML)-124K (17) | Audio-812K (3) | Peer-Review Report-269K (13) | Answering Reviewers-120K (16) | Received: 10/19/2025 | Revised: 12/21/2025 | Accepted: 01/28/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (994) | Similar Articles (79) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Prospective Study

Impact of visceral adiposity on glycemic variability in patients with insulin-treated type 2 diabetes undergoing hemodialysis

Pedro Gil-Millán, Ascensión Lupiañez, Sonia Caparrós, Alicia Ribas, Shaira Martínez-Vaquera, Ángel Ortiz-Zuñiga, Cristina Hernández, Rafael Simó, Olga Simó-Servat

World J Diabetes 17(3):115771. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.115771

Abstract (32) | Core Tip (35) | Full Article (HTML) (163) | Figures (1-2) (22) | Tables (1-3) (25) | Full Article (PDF)-842K (33) | Full Article with Cover (PDF)-1094K (13) | Full Article (XML)-130K (14) | Audio-302K (1) | Peer-Review Report-460K (13) | Answering Reviewers-137K (15) | Supplementary Material-159K (12) | Received: 10/24/2025 | Revised: 12/04/2025 | Accepted: 01/28/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (870) | Similar Articles (187) | Timeline of Article Publication (4) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Basic Study

Amomum villosum extract alleviates diabetic neuropathy via phosphoinositide 3-kinase/AKT-mediated antioxidative and anti-apoptotic effects

Dong-Quan Kou, Ming-Jie Liu, Xiao-Lan Gao, Fu-Rong Guo

World J Diabetes 17(3):113249. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.113249

Abstract (41) | Core Tip (34) | Full Article (HTML) (129) | Figures (1-6) (32) | Full Article (PDF)-5952K (22) | Full Article with Cover (PDF)-6230K (16) | Full Article (XML)-118K (13) | Audio-275K (2) | Peer-Review Report-306K (11) | Answering Reviewers-253K (12) | Received: 08/24/2025 | Revised: 11/12/2025 | Accepted: 01/23/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (846) | Similar Articles (0) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

SLC30A8 promoter hypermethylation is associated with type 2 diabetes and diabetic kidney disease in a Chinese population

Nan Li, Yu-Peng Li, Qing Xu, Jian Xu, Yi-Hong Yu, Juan Su, Chong Shen, Jiang-Yi Yu, Harvest F Gu

World J Diabetes 17(3):113947. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.113947

Abstract (35) | Core Tip (40) | Full Article (HTML) (162) | Figures (1-3) (28) | Tables (1-2) (35) | Full Article (PDF)-2952K (31) | Full Article with Cover (PDF)-3228K (18) | Full Article (XML)-143K (17) | Audio-1182K (4) | Peer-Review Report-230K (14) | Answering Reviewers-181K (12) | Supplementary Material-173K (15) | Received: 09/07/2025 | Revised: 10/25/2025 | Accepted: 12/25/2025 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1197) | Similar Articles (192) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

PRDX2 silencing alleviates reactive hyperplasia of Müller glial cells in diabetic retinopathy by inhibiting the RhoA/ROCK signaling pathway

Xiao-Lan Du, Shuai Ouyang, Yu-Song Wang, Yi-Shuang Mao, Bei-Cheng Ren, Wei-Hong Yu

World J Diabetes 17(3):115433. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.115433

Abstract (36) | Core Tip (45) | Full Article (HTML) (149) | Figures (1-6) (36) | Tables (1-3) (30) | Full Article (PDF)-16781K (25) | Full Article with Cover (PDF)-17030K (17) | Full Article (XML)-179K (18) | Audio-2446K (3) | Peer-Review Report-252K (14) | Answering Reviewers-136K (12) | Supplementary Material-1244K (13) | Received: 10/21/2025 | Revised: 12/26/2025 | Accepted: 01/22/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (1007) | Similar Articles (67) | Timeline of Article Publication (2) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Meta-Analysis

Machine learning and deep learning in predicting the risk of diabetic kidney disease: A systematic review and meta-analysis

Qing Chen, Hua-Wei Peng, Chen-Xiao Fu, Kai-Kai Meng, Jun-Bei Zhang

World J Diabetes 17(3):115097. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.115097

Abstract (39) | Core Tip (44) | Full Article (HTML) (168) | Figures (1-3) (28) | Tables (1-4) (36) | Full Article (PDF)-1354K (35) | Full Article with Cover (PDF)-1633K (19) | Full Article (XML)-152K (15) | Audio-1446K (4) | Peer-Review Report-266K (16) | Answering Reviewers-244K (14) | Supplementary Material-264K (14) | Received: 10/08/2025 | Revised: 11/18/2025 | Accepted: 02/04/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (886) | Similar Articles (237) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Case Report

Recurrent hypoglycemia in a young female with nesidioblastosis: A case report and review of literature

Shyam Bavaria, Amarpreet Chana, Khulud Mahmood Nurani, Joshua Kimang’a

World J Diabetes 17(3):116660. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.116660

Abstract (31) | Core Tip (61) | Full Article (HTML) (217) | Figures (1-4) (46) | Tables (1-2) (35) | Full Article (PDF)-22335K (46) | Full Article with Cover (PDF)-22589K (25) | Full Article (XML)-98K (15) | Audio-292K (2) | Peer-Review Report-256K (13) | Answering Reviewers-110K (14) | Received: 11/16/2025 | Revised: 01/10/2026 | Accepted: 02/05/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (705) | Similar Articles (4543) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Letter to the Editor

Zhejiang University index - connecting type 2 diabetes and metabolic dysfunction-associated steatotic liver disease: Clinical utility and future horizons

Tong-Jian Zhao, Yi-Xuan Xing, Nian-Zhe Sun

World J Diabetes 17(3):115669. Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.115669

Abstract (30) | Core Tip (42) | Full Article (HTML) (112) | Full Article (PDF)-361K (20) | Full Article with Cover (PDF)-642K (16) | Full Article (XML)-57K (12) | Audio-457K (3) | Peer-Review Report-239K (14) | Answering Reviewers-210K (12) | Received: 10/21/2025 | Revised: 11/26/2025 | Accepted: 12/19/2025 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (531) | Similar Articles (98) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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