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Contents Volume 17 Issue 5 May 15, 2026

Editorial

Synergistic mechanism of adipose-derived stem cells in healing diabetic foot ulcers

Xin-Xing Wan, Wei-Tao Yan, Wen-Hua He, Kun Xiong

World J Diabetes 17(5):116210. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.116210

Abstract (26) | Core Tip (24) | Full Article (HTML) (62) | Figures (1-1) (24) | Tables (1-1) (23) | Full Article (PDF)-647K (11) | Full Article with Cover (PDF)-887K (9) | Full Article (XML)-135K (3) | Audio-486K (2) | Peer-Review Report-278K (3) | Answering Reviewers-122K (4) | Supplementary Material-245K (4) | Received: 11/05/2025 | Revised: 12/22/2025 | Accepted: 01/07/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (300) | Similar Articles (31) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Opinion Review

ICAM-1 enigma in diabetic retinopathy: How population genetics challenges a universal pathogenesis model

Zhen-Yu Liu, Li-Xia Song, Zhi-Ran Yue, Si-Yan Huo, Fang-Jun Xu

World J Diabetes 17(5):116585. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.116585

Abstract (26) | Core Tip (24) | Full Article (HTML) (53) | Tables (1-1) (21) | Full Article (PDF)-419K (8) | Full Article with Cover (PDF)-658K (5) | Full Article (XML)-110K (4) | Audio-308K (1) | Peer-Review Report-242K (5) | Answering Reviewers-145K (4) | Received: 11/20/2025 | Revised: 01/08/2026 | Accepted: 01/22/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (460) | Similar Articles (87) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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When metabolic disease rewrites infection biology: Long-term multiorgan consequences of Helicobacter pylori infection in diabetes

Shree V Dhotre, Pradnya S Dhotre, Arunkumar Rao, Basavraj S Nagoba

World J Diabetes 17(5):118333. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.118333

Abstract (27) | Core Tip (22) | Full Article (HTML) (55) | Figures (1-3) (23) | Tables (1-3) (23) | Full Article (PDF)-2224K (5) | Full Article with Cover (PDF)-2463K (6) | Full Article (XML)-157K (6) | Audio-1562K (2) | Peer-Review Report-235K (5) | Answering Reviewers-106K (8) | Received: 12/29/2025 | Revised: 02/11/2026 | Accepted: 04/07/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (252) | Similar Articles (650) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Compound danshen dripping pills for non-proliferative diabetic retinopathy: Efficacy, mechanisms, and future directions

Jin-Wei Zhang

World J Diabetes 17(5):118684. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.118684

Abstract (25) | Core Tip (23) | Full Article (HTML) (63) | Tables (1-1) (24) | Full Article (PDF)-488K (6) | Full Article with Cover (PDF)-729K (6) | Full Article (XML)-168K (4) | Audio-554K (1) | Peer-Review Report-329K (4) | Answering Reviewers-81K (4) | Received: 01/09/2026 | Revised: 02/08/2026 | Accepted: 04/09/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (315) | Similar Articles (144) | Timeline of Article Publication (2) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Review

Diabetic kidney disease: Radiological assessment and clinical correlations

Salvatore Silipigni, Guido Gembillo, Lorenzo Lo Cicero, Serena Ausilia Ferrara, Maria Federica Ricca, Giuseppe Spadaro, Luca Soraci, Antonio Bottari

World J Diabetes 17(5):118278. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.118278

Abstract (28) | Core Tip (29) | Full Article (HTML) (87) | Figures (1-1) (26) | Tables (1-2) (35) | Full Article (PDF)-819K (16) | Full Article with Cover (PDF)-1059K (7) | Full Article (XML)-307K (4) | Audio-874K (3) | Peer-Review Report-193K (5) | Answering Reviewers-83K (4) | Received: 12/29/2025 | Revised: 01/30/2026 | Accepted: 03/10/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (295) | Similar Articles (37) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Type 2 diabetes, sex and metabolic dysfunction-associated steatotic liver disease

Amedeo Lonardo, Mohamad Jamalinia, Ralf Weiskirchen

World J Diabetes 17(5):119756. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.119756

Abstract (22) | Core Tip (29) | Full Article (HTML) (131) | Figures (1-3) (36) | Tables (1-3) (24) | Full Article (PDF)-3945K (13) | Full Article with Cover (PDF)-4181K (8) | Full Article (XML)-346K (4) | Audio-8328K (2) | Peer-Review Report-190K (3) | Answering Reviewers-206K (3) | Received: 02/04/2026 | Revised: 02/28/2026 | Accepted: 03/30/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (339) | Similar Articles (277) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Reader Comments (1) | Cite |

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Minireviews

From lipodystrophy to subcutaneous insulin depots: Overlooked mechanisms of glycemic variability in patients with diabetes

Nhi Thi Y Nguyen, Hau Phuc Tran, Thang Viet Luong, Dat Xuan Nguyen, Duong Hung Tran, Phuong Ho Thi Hoai, Meng-Chi Lee, Hai Nguyen Ngoc Dang

World J Diabetes 17(5):114042. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.114042

Abstract (32) | Core Tip (29) | Full Article (HTML) (93) | Figures (1-3) (23) | Tables (1-2) (24) | Full Article (PDF)-2491K (14) | Full Article with Cover (PDF)-2733K (4) | Full Article (XML)-84K (7) | Audio-237K (1) | Peer-Review Report-186K (5) | Answering Reviewers-96K (3) | Received: 09/09/2025 | Revised: 03/10/2026 | Accepted: 03/26/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (389) | Similar Articles (250) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Dual effects of synthetic phenolic antioxidants in type 2 diabetes mellitus: Mechanisms and advances

Xin Li, Peng-Cheng Yuan, Qian Gao, Qing-Qing Cao, Zhen Ma, Xuan Chen, Chong-Jian Wang, Zhen-Xing Mao, Wen-Qian Huo

World J Diabetes 17(5):115619. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.115619

Abstract (29) | Core Tip (23) | Full Article (HTML) (65) | Tables (1-2) (24) | Full Article (PDF)-465K (5) | Full Article with Cover (PDF)-701K (6) | Full Article (XML)-133K (7) | Audio-555K (1) | Peer-Review Report-189K (3) | Answering Reviewers-132K (4) | Received: 10/23/2025 | Revised: 12/17/2025 | Accepted: 02/06/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (249) | Similar Articles (149) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Unlocking pancreatic metabolic memory: Can early interventions reverse obesity and block diabetes before it strikes?

Yu-Jue Wang, Shuai-Yan Wang, Zi-Mu Li, Meng-Ying Zhao, Mo Zhou, Cong-Yi Xie, Jin-Ai Wang, Bin Xu, Guan-Hu Yang, Yun Liu, Tian-Cheng Xu

World J Diabetes 17(5):118754. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.118754

Abstract (35) | Core Tip (25) | Full Article (HTML) (385) | Figures (1-1) (25) | Tables (1-3) (25) | Full Article (PDF)-1351K (16) | Full Article with Cover (PDF)-1591K (12) | Full Article (XML)-228K (5) | Audio-856K (2) | Peer-Review Report-328K (3) | Answering Reviewers-145K (5) | Received: 01/09/2026 | Revised: 02/13/2026 | Accepted: 03/17/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (824) | Similar Articles (449) | Timeline of Article Publication (1) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Case Control Study

Vitamin D, vitamin D receptor FokI polymorphism, and diabetic retinopathy: A case-control study in Kunming, China

Ze-Hui Liu, Zhen-Qin Ran, Rong Yang, Li-Xin Chen, Zi-Zhou Wang, Yi-Yu Li, Rui Han

World J Diabetes 17(5):118141. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.118141

Abstract (24) | Core Tip (24) | Full Article (HTML) (61) | Figures (1-2) (27) | Tables (1-4) (26) | Full Article (PDF)-747K (9) | Full Article with Cover (PDF)-985K (8) | Full Article (XML)-98K (7) | Audio-222K (3) | Peer-Review Report-278K (4) | Answering Reviewers-156K (4) | Received: 12/24/2025 | Revised: 02/24/2026 | Accepted: 04/03/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (355) | Similar Articles (152) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Retrospective Cohort Study

Comparison of triglyceride-glucose index and its derived indices as markers for adverse pregnancy outcomes

Shu-Yu Li, Mei-Mei Hu, Lan-Lan Xiang, Yi-Tian Zhu, Yun Liu, Yi-Ting Chen, Ya-Jun Chen, Yu Zeng, Tian-Ying Zhong

World J Diabetes 17(5):117022. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.117022

Abstract (25) | Core Tip (25) | Full Article (HTML) (45) | Figures (1-4) (23) | Tables (1-3) (26) | Full Article (PDF)-2070K (6) | Full Article with Cover (PDF)-2310K (4) | Full Article (XML)-154K (4) | Audio-373K (1) | Peer-Review Report-255K (4) | Answering Reviewers-86K (3) | Supplementary Material-127K (4) | Received: 11/26/2025 | Revised: 01/25/2026 | Accepted: 03/16/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (503) | Similar Articles (10) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Observational Study

Association of obesity-related indices with chronic kidney disease risk in diabetes: A cross-sectional study

Dong-Ni Huang, Jing Ma, Qi Pan, Guo-Gang Xu, Li-Xin Guo

World J Diabetes 17(5):117338. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.117338

Abstract (23) | Core Tip (26) | Full Article (HTML) (60) | Figures (1-4) (23) | Tables (1-3) (26) | Full Article (PDF)-1671K (4) | Full Article with Cover (PDF)-1911K (7) | Full Article (XML)-133K (3) | Audio-826K (2) | Peer-Review Report-307K (3) | Answering Reviewers-243K (4) | Supplementary Material-67K (4) | Received: 12/04/2025 | Revised: 03/07/2026 | Accepted: 03/30/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (280) | Similar Articles (357) | Timeline of Article Publication (2) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Visceral fat area and remnant cholesterol in type 2 diabetes: Nonlinear associations and thresholds

Dong-Jian Chai, Chun-Yan Zhu, Yi-Ming Zhang, Zi-Chen Rao

World J Diabetes 17(5):117583. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.117583

Abstract (28) | Core Tip (23) | Full Article (HTML) (68) | Figures (1-1) (21) | Tables (1-4) (29) | Full Article (PDF)-703K (6) | Full Article with Cover (PDF)-927K (6) | Full Article (XML)-135K (6) | Audio-528K (1) | Peer-Review Report-274K (4) | Answering Reviewers-87K (7) | Received: 12/11/2025 | Revised: 01/16/2026 | Accepted: 03/10/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (531) | Similar Articles (144) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Basic Study

Association between high waist-height ratio and endoplasmic reticulum stress of young adults with insulin resistance

Oscar E Casillas, César A Hernández-Aguirre, Ana Gabriela Leija-Montoya, Tatiana Romero-García, J Gustavo Vázquez-Jiménez

World J Diabetes 17(5):116053. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.116053

Abstract (26) | Core Tip (24) | Full Article (HTML) (73) | Figures (1-4) (24) | Tables (1-1) (24) | Full Article (PDF)-1341K (9) | Full Article with Cover (PDF)-1558K (9) | Full Article (XML)-82K (6) | Audio-938K (1) | Peer-Review Report-293K (5) | Answering Reviewers-113K (4) | Supplementary Material-124K (6) | Received: 10/31/2025 | Revised: 12/12/2025 | Accepted: 01/30/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (570) | Similar Articles (138) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Gastric electrical stimulation ameliorates antral myenteric neurons in streptozotocin-induced diabetic beagle canines

Pan Tang, Xin Wu, Ji-Ri Xi, Ming-Yu Fu, Xiao-Wei Xue, Ying Jiang, Yang Zhao, He-Er Yang, Gui-Jun Fei, Xiao-Qing Li, Chun-Hua Hu, Xiu-Cai Fang

World J Diabetes 17(5):117132. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.117132

Abstract (26) | Core Tip (24) | Full Article (HTML) (77) | Figures (1-6) (23) | Tables (1-2) (22) | Full Article (PDF)-14959K (14) | Full Article with Cover (PDF)-15199K (6) | Full Article (XML)-109K (4) | Audio-420K (2) | Peer-Review Report-241K (3) | Answering Reviewers-94K (4) | Supplementary Material-76K (5) | Received: 11/29/2025 | Revised: 01/20/2026 | Accepted: 02/24/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (432) | Similar Articles (4) | Timeline of Article Publication (2) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Zuo Gui pill alleviates M1 macrophage polarization in type 2 diabetic osteoporosis through the Nrf2/HO-1/XCT/GPX4 pathway

Yi Zhao, Xiu-Zhi Feng, Wen-Qi Cao, Yi-Ran Chen, Ying Yang, Jing-Chi Liu, Ao Xu, Yan-Ling Ren, Zhi-Min Wang

World J Diabetes 17(5):117635. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.117635

Abstract (28) | Core Tip (28) | Full Article (HTML) (61) | Figures (1-5) (24) | Tables (1-1) (30) | Full Article (PDF)-28693K (9) | Full Article with Cover (PDF)-28931K (8) | Full Article (XML)-101K (6) | Audio-424K (1) | Peer-Review Report-505K (6) | Answering Reviewers-648K (7) | Supplementary Material-160K (7) | Received: 12/12/2025 | Revised: 01/08/2026 | Accepted: 02/24/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (644) | Similar Articles (0) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Network pharmacology: Anti-obesity and insulin-sensitizing effects of Danggui-Huangjing herb-pair via epidermal growth factor receptor/phosphatidylinositol 3-kinase/protein kinase B pathway

Wen-Jing Li, Jing-Jing Xu, Hannah Shi Tiang, Tong-Hua Liu, Li-Li Wu

World J Diabetes 17(5):118275. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.118275

Abstract (26) | Core Tip (26) | Full Article (HTML) (54) | Figures (1-9) (23) | Tables (1-2) (25) | Full Article (PDF)-23453K (7) | Full Article with Cover (PDF)-23689K (8) | Full Article (XML)-180K (4) | Audio-444K (2) | Peer-Review Report-464K (3) | Answering Reviewers-157K (3) | Received: 12/29/2025 | Revised: 02/08/2026 | Accepted: 03/16/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (306) | Similar Articles (32) | Timeline of Article Publication (2) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Meta-Analysis

Association between circulating CTRP12 levels and type 2 diabetes: A meta-analysis

Lei Chen, Cai-Bin Gao, Qiang Duan, Gang Shi, Qing-Sheng Niu

World J Diabetes 17(5):117237. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.117237

Abstract (26) | Core Tip (33) | Full Article (HTML) (109) | Figures (1-6) (24) | Tables (1-3) (25) | Full Article (PDF)-3898K (21) | Full Article with Cover (PDF)-4139K (7) | Full Article (XML)-120K (6) | Audio-9505K (3) | Peer-Review Report-239K (4) | Answering Reviewers-107K (5) | Received: 12/02/2025 | Revised: 01/25/2026 | Accepted: 03/04/2026 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (456) | Similar Articles (814) | Timeline of Article Publication (7) | Authors Evaluation (0) | Article Quality Tracking (0) | Cite |

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Correspondence

Letter to the Editor: Indirect bilirubin: A potential predictive biomarker for diabetic retinopathy and its clinical translational potential

Zhao Zhang, Xiao-Qian Shan, Feng-Ming Liang, Li-Xia Zhang

World J Diabetes 17(5):115813. Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.115813

Abstract (23) | Core Tip (22) | Full Article (HTML) (72) | Full Article (PDF)-396K (6) | Full Article with Cover (PDF)-637K (5) | Full Article (XML)-74K (3) | Audio-1292K (2) | Peer-Review Report-226K (3) | Answering Reviewers-127K (3) | Received: 10/25/2025 | Revised: 12/15/2025 | Accepted: 12/31/2025 | RCA | CrossRef | Google Scholar | Times Cited (0) | Total Visits (265) | Similar Articles (129) | Timeline of Article Publication (3) | Authors Evaluation (0) | Article Quality Tracking (1) | Cite |

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