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Impact of visceral adiposity on glycemic variability in patients with insulin-treated type 2 diabetes undergoing hemodialysis
Pedro Gil-Millán, Ascensión Lupiañez, Sonia Caparrós, Alicia Ribas, Shaira Martínez-Vaquera, Ángel Ortiz-Zuñiga, Cristina Hernández, Rafael Simó, Olga Simó-Servat
Pedro Gil-Millán, Ángel Ortiz-Zuñiga, Cristina Hernández, Rafael Simó, Olga Simó-Servat, Department of Endocrinology, Hospital Vall d´Hebron, Barcelona 08035, Catalonia, Spain
Pedro Gil-Millán, Department of Endocrinology, Diaverum España, Barcelona 08030, Catalonia, Spain
Pedro Gil-Millán, Department of Ciberdem, Instituto de Salud Carlos III, Madrid 28029, Spain
Ascensión Lupiañez, Department of Nutrition, Diaverum España, Barcelona 08030, Catalonia, Spain
Sonia Caparrós, Shaira Martínez-Vaquera, Department of Nephrology, Diaverum España, Barcelona 08030, Catalonia, Spain
Alicia Ribas, Department of Nurse, Diaverum España, Barcelona 08030, Catalonia, Spain
Ángel Ortiz-Zuñiga, Cristina Hernández, Rafael Simó, Olga Simó-Servat, Department of Ciberdem, Instituto Carlos III, Madrid 28029, Spain
Author contributions: Gil-Millán P was responsible for conceptualization, patient follow-up, statistical analyses, manuscript drafting, and editing; Lupiañez A was responsible for body composition assessments and supervision of multifrequency bioelectrical impedance analysis procedures; Caparrós S and Ribas A were responsible for patient follow-up and monitoring during hemodialysis sessions; Martínez-Vaquera S and Ortiz-Zuñiga A were responsible for statistical analyses and manuscript revision; Hernández C was responsible for conceptualization, supervision, manuscript editing, and funding acquisition; Simó R was responsible for conceptualization, supervision, manuscript writing, editing, and funding acquisition; Simó-Servat O was responsible for conceptualization, statistical analyses, manuscript writing, and editing; All authors read and approved the final version of the manuscript to be published.
Institutional review board statement: Approved by the Vall d’Hebron Ethics Committee, No. PR(AG)199/2024.
Clinical trial registration statement: This is a prospective study with no assigned intervention; therefore, clinical trial registration is not applicable.
Informed consent statement: All participants provided informed consent.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Data sharing statement: Data are available from the corresponding author upon reasonable request.
Corresponding author: Pedro Gil-Millán, MD, Department of Endocrinology, Hospital Vall d´Hebron, Paseo de la Vall d'Hebron, 119-129, Barcelona 08035, Catalonia, Spain.
pedroalejandro.gil@vallhebron.cat
Received: October 25, 2025
Revised: December 4, 2025
Accepted: January 28, 2026
Published online: March 15, 2026
Processing time: 138 Days and 21.3 Hours