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Contents Volume 16 Issue 6 June 15, 2024

Editorial

Dual primary gastric and colorectal cancer: The known hereditary causes and underlying mechanisms

Samy A Azer

World J Gastrointest Oncol 16(6):2264-2270. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2264

Abstract (616) | Core Tip (625) | Full Article (HTML) (2016) | Tables (1-1) (510) | Full Article (PDF)-417K (177) | Full Article with Cover (PDF)-729K (162) | Full Article (XML)-123K (137) | Audio-295K (16) | Peer-Review Report-172K (122) | Answering Reviewers-97K (150) | Received: 12/19/2023 | Revised: 03/03/2024 | Accepted: 04/07/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (5940) | Similar Articles (3) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (3) | Cite |

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Application of Fusobacterium nucleatum as a biomarker in gastrointestinal malignancies

Long-Chen Yu, Ya-Ping Li, Yue-Ming Xin, Mai Mao, Ya-Xin Pan, Yi-Xuan Qu, Zheng-Dong Luo, Yi Zhang, Xin Zhang

World J Gastrointest Oncol 16(6):2271-2283. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2271

Abstract (622) | Core Tip (621) | Full Article (HTML) (2881) | Figures (1-1) (488) | Tables (1-2) (570) | Full Article (PDF)-1456K (177) | Full Article with Cover (PDF)-1768K (224) | Full Article (XML)-243K (141) | Audio-1467K (12) | Peer-Review Report-176K (151) | Answering Reviewers-121K (141) | Received: 12/20/2023 | Revised: 04/08/2024 | Accepted: 04/28/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (9) | Total Visits (7678) | Similar Articles (66) | Timeline of Article Publication (2) | Authors Evaluation (1) | Article Quality Tracking (2) | Cite |

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T1 colorectal cancer management in the era of minimally invasive endoscopic resection

Shirley Xue Jiang, Aein Zarrin, Neal Shahidi

World J Gastrointest Oncol 16(6):2284-2294. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2284

Abstract (641) | Core Tip (786) | Full Article (HTML) (2080) | Figures (1-2) (495) | Tables (1-5) (686) | Full Article (PDF)-1126K (203) | Full Article with Cover (PDF)-1440K (241) | Full Article (XML)-221K (145) | Audio-1575K (12) | Peer-Review Report-221K (119) | Answering Reviewers-69K (113) | Received: 12/29/2023 | Revised: 04/02/2024 | Accepted: 04/24/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (5) | Total Visits (6927) | Similar Articles (230) | Timeline of Article Publication (1) | Authors Evaluation (2) | Article Quality Tracking (2) | Cite |

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Mixed neuroendocrine and adenocarcinoma of gastrointestinal tract: A complex diagnosis and therapeutic challenge

Santosh Shenoy

World J Gastrointest Oncol 16(6):2295-2299. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2295

Abstract (605) | Core Tip (679) | Full Article (HTML) (1834) | Full Article (PDF)-388K (154) | Full Article with Cover (PDF)-702K (163) | Full Article (XML)-65K (143) | Audio-601K (35) | Peer-Review Report-172K (141) | Answering Reviewers-53K (151) | Received: 01/08/2024 | Revised: 03/05/2024 | Accepted: 04/10/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (5265) | Similar Articles (0) | Timeline of Article Publication (3) | Authors Evaluation (1) | Article Quality Tracking (3) | Cite |

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Advancements in breath-based diagnostics for pancreatic cancer: Current insights and future perspectives

Mesut Tez, Eda Şahingöz, Hüseyin Fahri Martlı

World J Gastrointest Oncol 16(6):2300-2303. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2300

Abstract (590) | Core Tip (654) | Full Article (HTML) (1893) | Full Article (PDF)-364K (157) | Full Article with Cover (PDF)-678K (126) | Full Article (XML)-51K (107) | Audio-96K (6) | Peer-Review Report-314K (93) | Answering Reviewers-110K (102) | Received: 01/14/2024 | Revised: 04/21/2024 | Accepted: 04/29/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (5229) | Similar Articles (231) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (2) | Cite |

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Colorectal cancer and dormant metastases: Put to sleep or destroy?

Marina A Senchukova

World J Gastrointest Oncol 16(6):2304-2317. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2304

Abstract (608) | Core Tip (630) | Full Article (HTML) (1933) | Full Article (PDF)-502K (167) | Full Article with Cover (PDF)-812K (796) | Full Article (XML)-357K (119) | Audio-1444K (19) | Peer-Review Report-311K (100) | Answering Reviewers-95K (116) | Received: 02/24/2024 | Revised: 04/22/2024 | Accepted: 04/30/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (5) | Total Visits (6855) | Similar Articles (1185) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (2) | Cite |

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Review

Advances in targeted therapy for human epidermal growth factor receptor 2 positive in advanced gastric cancer

Ya-Kun Jiang, Wei Li, Ying-Yang Qiu, Meng Yue

World J Gastrointest Oncol 16(6):2318-2334. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2318

Abstract (615) | Core Tip (672) | Full Article (HTML) (2462) | Figures (1-7) (473) | Full Article (PDF)-10027K (199) | Full Article with Cover (PDF)-10337K (228) | Full Article (XML)-321K (122) | Audio-441K (13) | Peer-Review Report-231K (127) | Answering Reviewers-70K (121) | Supplementary Material-8723K (135) | Received: 12/11/2023 | Revised: 04/04/2024 | Accepted: 04/18/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (5) | Total Visits (6633) | Similar Articles (1319) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (2) | Cite |

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Research progress of ferroptosis regulating lipid peroxidation and metabolism in occurrence and development of primary liver cancer

Yu-Jie Shu, Bo Lao, Ying-Yang Qiu

World J Gastrointest Oncol 16(6):2335-2349. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2335

Abstract (583) | Core Tip (609) | Full Article (HTML) (2466) | Figures (1-5) (484) | Tables (1-1) (423) | Full Article (PDF)-10116K (193) | Full Article with Cover (PDF)-10426K (230) | Full Article (XML)-250K (165) | Audio-377K (10) | Peer-Review Report-215K (130) | Answering Reviewers-17K (129) | Received: 12/12/2023 | Revised: 03/06/2024 | Accepted: 04/11/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (6) | Total Visits (8019) | Similar Articles (71) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Early monitoring values of oncogenic signalling molecules for hepatocellular carcinoma

Min Yao, Rong-Fei Fang, Qun Xie, Min Xu, Wen-Li Sai, Deng-Fu Yao

World J Gastrointest Oncol 16(6):2350-2361. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2350

Abstract (553) | Core Tip (614) | Full Article (HTML) (1560) | Figures (1-4) (442) | Tables (1-1) (477) | Full Article (PDF)-3285K (165) | Full Article with Cover (PDF)-3597K (252) | Full Article (XML)-203K (119) | Audio-2695K (7) | Peer-Review Report-218K (122) | Answering Reviewers-152K (112) | Received: 02/22/2024 | Revised: 04/02/2024 | Accepted: 04/24/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (5989) | Similar Articles (28) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Minireviews

Therapeutic strategies targeting the epidermal growth factor receptor signaling pathway in metastatic colorectal cancer

Yi Zhou, Shuang Wu, Fan-Jie Qu

World J Gastrointest Oncol 16(6):2362-2379. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2362

Abstract (593) | Core Tip (607) | Full Article (HTML) (1746) | Figures (1-1) (463) | Tables (1-1) (432) | Full Article (PDF)-845K (152) | Full Article with Cover (PDF)-1156K (220) | Full Article (XML)-337K (123) | Audio-576K (9) | Peer-Review Report-215K (114) | Answering Reviewers-32K (116) | Received: 12/07/2023 | Revised: 02/13/2024 | Accepted: 04/01/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (5958) | Similar Articles (71) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Predicting the prognosis of hepatic arterial infusion chemotherapy in hepatocellular carcinoma

Qi-Feng Wang, Zong-Wei Li, Hai-Feng Zhou, Kun-Zhong Zhu, Ya-Jing Wang, Ya-Qin Wang, Yue-Wei Zhang

World J Gastrointest Oncol 16(6):2380-2393. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2380

Abstract (579) | Core Tip (640) | Full Article (HTML) (1895) | Figures (1-6) (468) | Tables (1-2) (510) | Full Article (PDF)-6724K (171) | Full Article with Cover (PDF)-7036K (183) | Full Article (XML)-189K (129) | Audio-779K (11) | Peer-Review Report-231K (125) | Answering Reviewers-467K (127) | Supplementary Material-1391K (138) | Received: 12/18/2023 | Revised: 01/19/2024 | Accepted: 04/03/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (6382) | Similar Articles (2142) | Timeline of Article Publication (0) | Authors Evaluation (4) | Article Quality Tracking (1) | Cite |

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Unraveling colorectal cancer prevention: The vitamin D - gut flora - immune system nexus

Zhi-Song Zhan, Zu-Shun Zheng, Jing Shi, Juan Chen, Si-Yi Wu, Shi-Yan Zhang

World J Gastrointest Oncol 16(6):2394-2403. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2394

Abstract (559) | Core Tip (640) | Full Article (HTML) (2042) | Figures (1-1) (396) | Full Article (PDF)-1186K (185) | Full Article with Cover (PDF)-1498K (292) | Full Article (XML)-165K (166) | Audio-682K (12) | Peer-Review Report-180K (160) | Answering Reviewers-65K (128) | Received: 12/26/2023 | Revised: 03/02/2024 | Accepted: 04/11/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (8) | Total Visits (5775) | Similar Articles (1237) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Retrospective Cohort Study

Unveiling the secrets of gastrointestinal mucous adenocarcinoma survival after surgery with artificial intelligence: A population-based study

Jie Song, Xiang-Xiu Yan, Fang-Liang Zhang, Yong-Yi Lei, Zi-Yin Ke, Fang Li, Kai Zhang, Yu-Qi He, Wei Li, Chao Li, Yuan-Ming Pan

World J Gastrointest Oncol 16(6):2404-2418. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2404

Abstract (571) | Core Tip (613) | Full Article (HTML) (1756) | Figures (1-5) (515) | Tables (1-4) (438) | Full Article (PDF)-6918K (160) | Full Article with Cover (PDF)-7231K (220) | Full Article (XML)-131K (121) | Audio-257K (13) | Peer-Review Report-311K (104) | Answering Reviewers-291K (125) | Supplementary Material-870K (147) | Received: 12/29/2023 | Revised: 02/27/2024 | Accepted: 04/03/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (6949) | Similar Articles (145) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Analysis of metabolic characteristics of metabolic syndrome in elderly patients with gastric cancer by non-targeted metabolomics

Huan Zhang, Wen-Bing Shen, Lin Chen

World J Gastrointest Oncol 16(6):2419-2428. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2419

Abstract (582) | Core Tip (557) | Full Article (HTML) (1624) | Figures (1-2) (396) | Tables (1-5) (379) | Full Article (PDF)-1147K (185) | Full Article with Cover (PDF)-1460K (197) | Full Article (XML)-116K (131) | Audio-640K (12) | Peer-Review Report-171K (120) | Answering Reviewers-43K (104) | Received: 03/09/2024 | Revised: 04/29/2024 | Accepted: 05/16/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (6385) | Similar Articles (1371) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Retrospective Study

Predictive value of preoperative routine examination for the prognosis of patients with pT2N0M0 or pT3N0M0 colorectal cancer

Peng-Fei Jing, Jin Chen, En-Da Yu, Chao-Yu Miao

World J Gastrointest Oncol 16(6):2429-2438. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2429

Abstract (602) | Core Tip (592) | Full Article (HTML) (1671) | Figures (1-1) (424) | Tables (1-4) (422) | Full Article (PDF)-735K (144) | Full Article with Cover (PDF)-1049K (218) | Full Article (XML)-117K (151) | Audio-2406K (10) | Peer-Review Report-205K (109) | Answering Reviewers-113K (141) | Received: 11/24/2023 | Revised: 03/03/2024 | Accepted: 04/09/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (6187) | Similar Articles (1140) | Timeline of Article Publication (2) | Authors Evaluation (2) | Article Quality Tracking (1) | Cite |

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Simplified liver imaging reporting and data system for the diagnosis of hepatocellular carcinoma on gadoxetic acid-enhanced magnetic resonance imaging

Rong Lyu, Wei-Juan Hu, Di Wang, Jiao Wang, Yu-Bing Ye, Ke-Feng Jia

World J Gastrointest Oncol 16(6):2439-2448. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2439

Abstract (549) | Core Tip (615) | Full Article (HTML) (1751) | Figures (1-3) (501) | Tables (1-3) (421) | Full Article (PDF)-2910K (133) | Full Article with Cover (PDF)-3226K (159) | Full Article (XML)-74K (119) | Audio-611K (17) | Peer-Review Report-181K (105) | Answering Reviewers-461K (96) | Received: 12/11/2023 | Revised: 02/28/2024 | Accepted: 04/11/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (6095) | Similar Articles (3045) | Timeline of Article Publication (2) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Efficacy comparison of fruquintinib, regorafenib monotherapy or plus programmed death-1 inhibitors for microsatellite stable metastatic colorectal cancer

Tian-Qi An, Hui Qiu, Quan-Bo Zhou, Hong Zong, Shuang Hu, Yu-Gui Lian, Rui-Hua Zhao

World J Gastrointest Oncol 16(6):2449-2462. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2449

Abstract (572) | Core Tip (573) | Full Article (HTML) (2756) | Figures (1-4) (460) | Tables (1-6) (400) | Full Article (PDF)-1368K (214) | Full Article with Cover (PDF)-1682K (202) | Full Article (XML)-157K (108) | Audio-739K (17) | Peer-Review Report-173K (110) | Answering Reviewers-255K (109) | Supplementary Material-956K (108) | Received: 12/20/2023 | Revised: 02/20/2024 | Accepted: 04/07/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (5) | Total Visits (7453) | Similar Articles (1148) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Development of a diagnostic nomogram for alpha-fetoprotein-negative hepatocellular carcinoma based on serological biomarkers

Li He, Cui Zhang, Lan-Lan Liu, Li-Ping Huang, Wen-Jing Lu, Yuan-Yuan Zhang, De-Yong Zou, Yu-Fei Wang, Qing Zhang, Xiao-Li Yang

World J Gastrointest Oncol 16(6):2463-2475. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2463

Abstract (536) | Core Tip (568) | Full Article (HTML) (1718) | Figures (1-6) (473) | Tables (1-4) (434) | Full Article (PDF)-1577K (156) | Full Article with Cover (PDF)-1890K (291) | Full Article (XML)-128K (127) | Audio-1381K (12) | Peer-Review Report-217K (118) | Answering Reviewers-49K (116) | Supplementary Material-199K (127) | Received: 01/23/2024 | Revised: 02/12/2024 | Accepted: 04/01/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (6444) | Similar Articles (2049) | Timeline of Article Publication (0) | Authors Evaluation (2) | Article Quality Tracking (1) | Cite |

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Drug-eluting bead transarterial chemoembolization as neoadjuvant therapy pre-liver transplantation for advanced-stage hepatocellular carcinoma

Zhao-Dan Ye, Li Zhuang, Meng-Chen Song, Zhe Yang, Wu Zhang, Jing-Feng Zhang, Guo-Hong Cao

World J Gastrointest Oncol 16(6):2476-2486. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2476

Abstract (543) | Core Tip (573) | Full Article (HTML) (1766) | Figures (1-5) (441) | Tables (1-4) (391) | Full Article (PDF)-5831K (154) | Full Article with Cover (PDF)-6145K (153) | Full Article (XML)-115K (124) | Audio-569K (9) | Peer-Review Report-173K (108) | Answering Reviewers-89K (115) | Received: 01/29/2024 | Revised: 03/17/2024 | Accepted: 04/18/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (6111) | Similar Articles (2345) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Association between Helicobacter pylori infection, mismatch repair, HER2 and tumor-infiltrating lymphocytes in gastric cancer

Carlos A Castaneda, Miluska Castillo, Luis A Bernabe, Joselyn Sanchez, Matteo Fassan, Katherine Tello, Ignacio Ivan Wistuba, Ivan Chavez Passiuri, Eloy Ruiz, Juvenal Sanchez, Fernando Barreda, Daniel Valdivia, Yaqueline Bazan, Milagros Abad-Licham, Claudio Mengoa, Hugo Fuentes, Paola Montenegro, Ebert Poquioma, Raul Alatrista, Claudio J Flores, Luis Taxa

World J Gastrointest Oncol 16(6):2487-2503. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2487

Abstract (588) | Core Tip (626) | Full Article (HTML) (2276) | Figures (1-3) (490) | Tables (1-4) (401) | Full Article (PDF)-28891K (234) | Full Article with Cover (PDF)-29202K (178) | Full Article (XML)-224K (145) | Audio-252K (15) | Peer-Review Report-217K (141) | Answering Reviewers-173K (120) | Received: 02/07/2024 | Revised: 04/04/2024 | Accepted: 04/11/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (7501) | Similar Articles (1307) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Impact of baseline hepatitis B virus viral load on the long-term prognosis of advanced hepatocellular carcinoma treated with immunotherapy

Di Pan, Hao-Nan Liu, Zhi-Yuan Yao, Xiao-Xiao Chen, Yu-Qi Li, Jing-Jing Zhu, Zheng-Xiang Han, Xiao-Bing Qin

World J Gastrointest Oncol 16(6):2504-2519. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2504

Abstract (602) | Core Tip (651) | Full Article (HTML) (2062) | Figures (1-5) (513) | Tables (1-7) (585) | Full Article (PDF)-1754K (189) | Full Article with Cover (PDF)-2067K (153) | Full Article (XML)-174K (133) | Audio-277K (8) | Peer-Review Report-216K (126) | Answering Reviewers-93K (140) | Received: 02/18/2024 | Revised: 04/21/2024 | Accepted: 04/26/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (4) | Total Visits (7652) | Similar Articles (2239) | Timeline of Article Publication (2) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Prediction of pathological complete response and prognosis in locally advanced rectal cancer

Yi-Jun Xu, Dan Tao, Song-Bing Qin, Xiao-Yan Xu, Kai-Wen Yang, Zhong-Xu Xing, Ju-Ying Zhou, Yang Jiao, Li-Li Wang

World J Gastrointest Oncol 16(6):2520-2530. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2520

Abstract (571) | Core Tip (637) | Full Article (HTML) (2044) | Figures (1-1) (428) | Tables (1-3) (460) | Full Article (PDF)-652K (160) | Full Article with Cover (PDF)-967K (181) | Full Article (XML)-110K (195) | Audio-291K (15) | Peer-Review Report-171K (149) | Answering Reviewers-143K (118) | Received: 02/22/2024 | Revised: 03/18/2024 | Accepted: 04/24/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (8) | Total Visits (8155) | Similar Articles (316) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Observational Study

Extrahepatic cholestasis associated with paracoccidioidomycosis: Challenges in the differential diagnosis of biliopancreatic neoplasia

José Sebastião dos Santos, Vitor de Moura Arrais, William José Rosseto Ferreira, Ricardo Ribeiro Correa Filho, Mariângela Ottoboni Brunaldi, Rafael Kemp, Ajith Kumar Sankanrakutty, Jorge Elias Junior, Fernando Bellissimo-Rodrigues, Roberto Martinez, Edson Zangiacomi Martinez, José Celso Ardengh

World J Gastrointest Oncol 16(6):2531-2540. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2531

Abstract (582) | Core Tip (647) | Full Article (HTML) (1279) | Figures (1-5) (421) | Tables (1-3) (495) | Full Article (PDF)-11758K (174) | Full Article with Cover (PDF)-12072K (186) | Full Article (XML)-67K (116) | Audio-2210K (19) | Peer-Review Report-310K (111) | Answering Reviewers-142K (127) | Received: 01/15/2024 | Revised: 03/20/2024 | Accepted: 04/19/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (6466) | Similar Articles (320) | Timeline of Article Publication (0) | Authors Evaluation (0) | Article Quality Tracking (1) | Cite |

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Clinical and Translational Research

Development of a novel staging classification for Siewert II adenocarcinoma of the esophagogastric junction after neoadjuvant chemotherapy

Jian Zhang, Hao Liu, Hang Yu, Wei-Xiang Xu

World J Gastrointest Oncol 16(6):2541-2554. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2541

Abstract (571) | Core Tip (568) | Full Article (HTML) (1623) | Figures (1-3) (455) | Tables (1-4) (442) | Full Article (PDF)-1401K (230) | Full Article with Cover (PDF)-1716K (277) | Full Article (XML)-118K (117) | Audio-214K (5) | Peer-Review Report-169K (112) | Answering Reviewers-79K (93) | Received: 10/21/2023 | Revised: 03/09/2024 | Accepted: 04/15/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (5929) | Similar Articles (41) | Timeline of Article Publication (0) | Article Quality Tracking (1) | Cite |

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N6-methyladenosine methylation regulates the tumor microenvironment of Epstein-Barr virus-associated gastric cancer

Yu Zhang, Fang Zhou, Ming-Yu Zhang, Li-Na Feng, Jia-Lun Guan, Ruo-Nan Dong, Yu-Jie Huang, Su-Hong Xia, Jia-Zhi Liao, Kai Zhao

World J Gastrointest Oncol 16(6):2555-2570. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2555

Abstract (507) | Core Tip (546) | Full Article (HTML) (2450) | Figures (1-7) (425) | Full Article (PDF)-7997K (156) | Full Article with Cover (PDF)-8308K (150) | Full Article (XML)-130K (140) | Audio-1298K (10) | Peer-Review Report-171K (106) | Answering Reviewers-186K (115) | Received: 12/19/2023 | Revised: 02/18/2024 | Accepted: 04/08/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (5) | Total Visits (5999) | Similar Articles (1335) | Timeline of Article Publication (2) | Authors Evaluation (2) | Article Quality Tracking (1) | Cite |

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Hepatocellular carcinoma: An analysis of the expression status of stress granules and their prognostic value

Qing-Shuai Ren, Qiu Sun, Shu-Qin Cheng, Li-Ming Du, Ping-Xuan Guo

World J Gastrointest Oncol 16(6):2571-2591. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2571

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Comprehensive analysis of clinical and biological value of ING family genes in liver cancer

Shi-Cai Liu

World J Gastrointest Oncol 16(6):2592-2609. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2592

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Epidemiology and prognostic nomogram for locally advanced gastric signet ring cell carcinoma: A population-based study

Ze-Hao Yu, Lei-Ming Zhang, Zhi-Qi Dai, Meng-Na Zhang, Si-Ming Zheng

World J Gastrointest Oncol 16(6):2610-2630. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2610

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Socioeconomic traits and the risk of Barrett’s esophagus and gastroesophageal reflux disease: A Mendelian randomization study

Yu-Xin Liu, Cheng-Li Bin, Lu Zhang, Wen-Tao Yang, Bai-Ping An

World J Gastrointest Oncol 16(6):2631-2645. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2631

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Basic Study

Complement factor I knockdown inhibits colon cancer development by affecting Wnt/β-catenin/c-Myc signaling pathway and glycolysis

Yong-Jun Du, Yue Jiang, Yan-Mei Hou, Yong-Bo Shi

World J Gastrointest Oncol 16(6):2646-2662. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2646

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Fine-needle aspiration technique under endoscopic ultrasound guidance: A technical approach for RNA profiling of pancreatic neoplasms

Sabina Sherafedinovna Seyfedinova, Olga Aleksandrovna Freylikhman, Polina Sergeevna Sokolnikova, Konstantin Aleksandrovich Samochernykh, Anna Aleksandrovna Kostareva, Olga Viktorovna Kalinina, Evgeniy Gennadievich Solonitsyn

World J Gastrointest Oncol 16(6):2663-2672. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2663

Abstract (559) | Core Tip (609) | Full Article (HTML) (1722) | Figures (1-2) (478) | Tables (1-1) (426) | Full Article (PDF)-1494K (170) | Full Article with Cover (PDF)-1807K (216) | Full Article (XML)-111K (128) | Audio-224K (25) | Peer-Review Report-171K (141) | Answering Reviewers-76K (119) | Received: 12/26/2023 | Revised: 02/18/2024 | Accepted: 04/07/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (6265) | Similar Articles (23) | Timeline of Article Publication (0) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

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Comprehensive analysis of gene mutations and mismatch repair in Chinese colorectal cancer patients

Huang Chen, Rui-Ying Jiang, Zhan Hua, Xiao-Wei Wang, Xiao-Li Shi, Ye Wang, Qian-Qian Feng, Jie Luo, Wu Ning, Yan-Fen Shi, Da-Kui Zhang, Bei Wang, Jian-Zheng Jie, Ding-Rong Zhong

World J Gastrointest Oncol 16(6):2673-2682. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2673

Abstract (571) | Core Tip (611) | Full Article (HTML) (1810) | Figures (1-4) (446) | Tables (1-3) (417) | Full Article (PDF)-1643K (162) | Full Article with Cover (PDF)-1956K (202) | Full Article (XML)-98K (138) | Audio-269K (17) | Peer-Review Report-170K (124) | Answering Reviewers-215K (136) | Supplementary Material-308K (125) | Received: 12/04/2023 | Revised: 02/23/2024 | Accepted: 04/12/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (7857) | Similar Articles (1142) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Action of circulating and infiltrating B cells in the immune microenvironment of colorectal cancer by single-cell sequencing analysis

Jing-Po Zhang, Bing-Zheng Yan, Jie Liu, Wei Wang

World J Gastrointest Oncol 16(6):2683-2696. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2683

Abstract (584) | Core Tip (613) | Full Article (HTML) (2003) | Figures (1-9) (447) | Full Article (PDF)-6432K (160) | Full Article with Cover (PDF)-6745K (211) | Full Article (XML)-148K (129) | Audio-594K (9) | Peer-Review Report-227K (129) | Answering Reviewers-2784K (126) | Received: 12/12/2023 | Revised: 03/10/2024 | Accepted: 04/09/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (5854) | Similar Articles (1144) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Bidirectional effects of the tryptophan metabolite indole-3-acetaldehyde on colorectal cancer

Ze Dai, Kai-Li Deng, Xiao-Mei Wang, Dong-Xue Yang, Chun-Lan Tang, Yu-Ping Zhou

World J Gastrointest Oncol 16(6):2697-2715. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2697

Abstract (546) | Core Tip (570) | Full Article (HTML) (2622) | Figures (1-7) (393) | Tables (1-2) (445) | Full Article (PDF)-22724K (236) | Full Article with Cover (PDF)-23033K (172) | Full Article (XML)-147K (147) | Audio-830K (10) | Peer-Review Report-227K (114) | Answering Reviewers-3901K (151) | Received: 12/17/2023 | Revised: 02/13/2024 | Accepted: 03/25/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (11) | Total Visits (7328) | Similar Articles (1140) | Timeline of Article Publication (12) | Authors Evaluation (2) | Article Quality Tracking (0) | Cite |

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Sm-like 5 knockdown inhibits proliferation and promotes apoptosis of colon cancer cells by upregulating p53, CDKN1A and TNFRSF10B

Cai-Jing Mo, Xiao-Yuan Deng, Ru-Lan Ma, Kun Zhu, Lei Shi, Kang Li

World J Gastrointest Oncol 16(6):2716-2726. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2716

Abstract (555) | Core Tip (604) | Full Article (HTML) (1745) | Figures (1-7) (394) | Tables (1-2) (441) | Full Article (PDF)-7135K (160) | Full Article with Cover (PDF)-7448K (201) | Full Article (XML)-82K (128) | Audio-740K (10) | Peer-Review Report-219K (126) | Answering Reviewers-75K (147) | Supplementary Material-95K (151) | Received: 12/27/2023 | Revised: 02/09/2024 | Accepted: 04/15/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (5) | Total Visits (6318) | Similar Articles (512) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Shi-pi-xiao-ji formula suppresses hepatocellular carcinoma by reducing cellular stiffness through upregulation of acetyl-coA acetyltransferase 1

Hui-Ying Jian, Zi-Cheng Liang, Huan Wen, Zhen Zhang, Pu-Hua Zeng

World J Gastrointest Oncol 16(6):2727-2741. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2727

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Aspirin suppresses hepatocellular carcinoma progression by inhibiting platelet activity

Li-Jun Zhao, Zhi-Yin Wang, Wei-Ting Liu, Li-Li Yu, Hao-Nan Qi, Jie Ren, Chen-Guang Zhang

World J Gastrointest Oncol 16(6):2742-2756. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2742

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Circ_0004592: An auxiliary diagnostic biomarker for gastric cancer

Shan Kong, Yan-Hua Xu, Ming Zheng, Shao-Qing Ju, Heng-Chuan Shi

World J Gastrointest Oncol 16(6):2757-2768. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2757

Abstract (511) | Core Tip (577) | Full Article (HTML) (1514) | Figures (1-5) (410) | Tables (1-4) (407) | Full Article (PDF)-4183K (169) | Full Article with Cover (PDF)-4496K (244) | Full Article (XML)-117K (135) | Audio-313K (17) | Peer-Review Report-338K (125) | Answering Reviewers-247K (154) | Supplementary Material-136K (154) | Received: 01/29/2024 | Revised: 03/12/2024 | Accepted: 04/12/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (4) | Total Visits (6527) | Similar Articles (1346) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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N-glycosylation of Wnt3 regulates the progression of hepatocellular carcinoma by affecting Wnt/β-catenin signal pathway

Xin-Zhan Zhang, Xiao-Chuan Mo, Zhu-Ting Wang, Rong Sun, Da-Quan Sun

World J Gastrointest Oncol 16(6):2769-2780. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2769

Abstract (575) | Core Tip (511) | Full Article (HTML) (1735) | Figures (1-4) (424) | Tables (1-1) (412) | Full Article (PDF)-20648K (183) | Full Article with Cover (PDF)-20961K (195) | Full Article (XML)-80K (114) | Audio-1469K (17) | Peer-Review Report-217K (122) | Answering Reviewers-40K (141) | Received: 03/07/2024 | Revised: 04/25/2024 | Accepted: 04/28/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (4) | Total Visits (6307) | Similar Articles (1884) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Systematic Reviews

Ferroptosis regulating lipid peroxidation metabolism in the occurrence and development of gastric cancer

Lan-Mei Wang, Wei-Wei Zhang, Ying-Yang Qiu, Fang Wang

World J Gastrointest Oncol 16(6):2781-2792. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2781

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Meta-Analysis

Meta-analysis of transarterial chemoembolization combined with cryoablation vs transarterial chemoembolization alone for ≥ 5 cm hepatocellular carcinoma

Jie-Fei Cheng, Qiu-Lian Sun, Ling Tang, Xin-Jian Xu, Xiang-Zhong Huang

World J Gastrointest Oncol 16(6):2793-2803. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2793

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Dynamic contrast enhanced ultrasound in differential diagnosis of hepatocellular carcinoma: A systematic review and meta-analysis

Giorgio Esposto, Paolo Santini, Fabrizio Termite, Linda Galasso, Irene Mignini, Maria Elena Ainora, Antonio Gasbarrini, Maria Assunta Zocco

World J Gastrointest Oncol 16(6):2804-2815. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2804

Abstract (601) | Core Tip (620) | Full Article (HTML) (1956) | Figures (1-4) (453) | Tables (1-4) (417) | Full Article (PDF)-1946K (190) | Full Article with Cover (PDF)-2261K (192) | Full Article (XML)-106K (154) | Audio-629K (22) | Peer-Review Report-215K (142) | Answering Reviewers-31K (132) | Supplementary Material-604K (130) | Received: 01/20/2024 | Revised: 04/16/2024 | Accepted: 04/28/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (7) | Total Visits (6680) | Similar Articles (1876) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Correlation analysis of interstitial maturity and prognosis of colorectal cancer: Meta-analysis

Zhen-Jun Liu, Xu-Wen Zhang, Qi-Qi Liu, Shao-Zhao Wang

World J Gastrointest Oncol 16(6):2816-2825. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2816

Abstract (572) | Core Tip (607) | Full Article (HTML) (1323) | Figures (1-4) (429) | Tables (1-2) (487) | Full Article (PDF)-2970K (149) | Full Article with Cover (PDF)-3284K (219) | Full Article (XML)-112K (138) | Audio-551K (7) | Peer-Review Report-244K (102) | Answering Reviewers-88K (112) | Received: 02/21/2024 | Revised: 04/13/2024 | Accepted: 04/23/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (5660) | Similar Articles (665) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Scientometrics

Visualization analysis of research hotspots and trends on gastrointestinal tumor organoids

Gang Wang, Tao Liu, Wen-Ting He

World J Gastrointest Oncol 16(6):2826-2841. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2826

Abstract (581) | Core Tip (594) | Full Article (HTML) (2291) | Figures (1-7) (434) | Tables (1-5) (388) | Full Article (PDF)-26171K (201) | Full Article with Cover (PDF)-26482K (204) | Full Article (XML)-123K (142) | Audio-1376K (18) | Peer-Review Report-169K (133) | Answering Reviewers-121K (130) | Received: 12/24/2023 | Revised: 03/09/2024 | Accepted: 04/19/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (6795) | Similar Articles (0) | Timeline of Article Publication (21) | Authors Evaluation (12) | Article Quality Tracking (0) | Cite |

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Trends and hotspots in gastrointestinal neoplasms risk assessment: A bibliometric analysis from 1984 to 2022

Qiang-Qiang Fu, Le Ma, Xiao-Min Niu, Hua-Xin Zhao, Xu-Hua Ge, Hua Jin, De-Hua Yu, Sen Yang

World J Gastrointest Oncol 16(6):2842-2861. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2842

Abstract (577) | Core Tip (596) | Full Article (HTML) (1937) | Figures (1-5) (499) | Tables (1-10) (378) | Full Article (PDF)-15405K (194) | Full Article with Cover (PDF)-15716K (260) | Full Article (XML)-267K (152) | Audio-329K (12) | Peer-Review Report-229K (122) | Answering Reviewers-220K (143) | Supplementary Material-297K (122) | Received: 01/12/2024 | Revised: 03/10/2024 | Accepted: 04/15/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (7073) | Similar Articles (32) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Letter to the Editor

New perspectives in prognostication of hepatocellular carcinoma: The role and clinical implications of transient receptor potential family genes

Shi-Hao Guan, Wen-Jing Hu, Xin-Yu Wang, Yue-Xia Gu, De-Hua Zhou

World J Gastrointest Oncol 16(6):2862-2864. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2862

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Retraction Note

Retraction note to: RNA-binding protein CPSF6 regulates IBSP to affect pyroptosis in gastric cancer

Xue-Jun Wang, Yong Liu, Bin Ke, Li Zhang, Han Liang

World J Gastrointest Oncol 16(6):2865-2866. Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2865

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