Ferroptosis regulating lipid peroxidation metabolism in the occurrence and development of gastric cancer

Figure 1 Mechanisms of ferroptosis. Created with BioRender.com.

Figure 2 The interaction of ferroptosis and lipid metabolism in tumor biology. Created with BioRender.com.

Figure 3 Ferroptosis can occur through two major pathways, the extrinsic or transporter-dependent pathway. Created with BioRender.com.

Figure 4 NFE2L2 in ferroptosis. A: NFE2L2 binds to KEAP1; B: NFE2L2 is separated from KEAP1. Created with BioRender.com.

Figure 5 Oxidative damage in ferroptosis. Created with BioRender.com.

Figure 6 Dual role of ferroptosis in tumor immunity. A: CD8+ T cells activate the iron death pathway in tumor cells; B: Activation of ferroptosis correlates with the polarization of M2 macrophages. Created with BioRender.com.