Trends and hotspots in gastrointestinal neoplasms risk assessment: A bibliometric analysis from 1984 to 2022

Table 1 Methodological framework for bibliometric analysis of gastrointestinal neoplasm risk assessment literature

Parameter	Description
Database	Web of Science Core Collection
Search period	25-Oct-22
Search strategy	Keywords related to colorectal cancer and risk assessment, combined as (1 OR 2 OR 3) AND 4
Screening process	Two investigators manually screened titles, abstracts, and full texts, resulting in 1371 articles and reviews selected for analysis
Analysis software	VOSviewer (1.6.18), CiteSpace (V6.1.R4), Bibliometrix (4.1.2)
Analysis focus	Coauthorship, keyword cooccurrence, international collaboration, cocitation, clustering analysis, citation trends, and research topic evolution over time
Visualization Techniques	Node size reflects citation or occurrence frequency; line connections indicate relationships; color variations represent different clusters or average occurrence years

Table 2 The citations and output of publications worldwide

Year	Publications	Mean total citations per year	Mean total citations per article	Year	Publications	Mean total citations per year	Mean total citations per article
2022	112	0.35	0.99	2002	20	2.38	47.65
2021	118	7.93	7.63	2001	15	3.06	64.33
2020	109	4.41	8.83	2000	15	2.3	50.67
2019	88	5.57	16.72	1999	17	1.03	23.65
2018	88	7.38	29.53	1998	5	16.62	398.8
2017	80	4.4	22	1997	8	1.84	46
2016	84	4.64	27.86	1996	9	0.92	24
2015	92	5.19	36.35	1995	5	2.4	64.8
2014	65	6.75	53.97	1994	5	2.46	69
2013	67	3.63	32.66	1993	4	1.91	55.5
2012	53	3.97	39.68	1992	4	2.92	87.75
2011	45	4	43.98	1991	4	4.51	139.75
2010	36	5.42	65.08	1990	0	0	121
2009	40	4.24	55.15	1989	0	0	47.65
2008	27	3.24	45.33	1988	0	0	64.33
2007	31	2.74	41.06	1987	0	0	50.67
2006	37	6.06	96.92	1986	0	0	23.65
2005	29	6.22	105.76	1985	0	0	398.8
2004	23	3.59	64.57	1984	1	3.18	46
2003	14	2.89	54.86	NA	NA	NA	NA

Table 3 Top 20 most common countries of authors in the research field of risk assessment for gastrointestinal neoplasms

Rank	Country	Articles	Freq	SCP	MCP	MCP_Ratio
1	United States	516	0.38025	433	83	0.1609
2	China	199	0.14665	176	23	0.1156
3	United Kingdom	74	0.05453	49	25	0.3378
4	Japan	65	0.0479	57	8	0.1231
5	Germany	54	0.03979	37	17	0.3148
6	Australia	52	0.03832	26	26	0.5
7	Italy	47	0.03464	38	9	0.1915
8	Netherlands	47	0.03464	37	10	0.2128
9	Canada	34	0.02506	19	15	0.4412
10	Korea	32	0.02358	30	2	0.0625
11	Spain	18	0.01326	12	6	0.3333
12	France	17	0.01253	11	6	0.3529
13	Denmark	16	0.01179	12	4	0.25
14	India	15	0.01105	13	2	0.1333
15	Sweden	14	0.01032	13	1	0.0714
16	Poland	11	0.00811	6	5	0.4545
17	Switzerland	11	0.00811	8	3	0.2727
18	Brazil	10	0.00737	9	1	0.1
19	Iran	10	0.00737	10	0	0
20	Norway	10	0.00737	7	3	0.3

Table 4 Top 20 most productive institutions in the research field of risk assessment for gastrointestinal neoplasms

Rank	Institutions	Publications	Percentage of 1371	Total link strength	Total citations	Average citation per paper
1	Brigham and Womens Hosp	41	2.99	168	2855	69.63
2	Nci	39	2.84	42	2060	52.82
3	Harvard Univ	36	2.63	120	3721	103.36
4	Dana Farber Canc Inst	35	2.55	142	2635	75.29
5	Univ Texas Md Anderson Canc Ctr	30	2.19	79	1074	35.8
6	Univ Melbourne	24	1.75	81	759	31.63
7	Univ Michigan	23	1.68	92	1042	45.3
8	Univ Toronto	23	1.68	75	667	29
9	Duke Univ	22	1.6	75	994	45.18
10	Mayo Clin	22	1.6	45	1283	58.32
11	Johns Hopkins Univ	21	1.53	104	3262	155.33
12	Univ Washington	21	1.53	71	1372	65.33
13	Ohio State Univ	20	1.46	53	1030	51.5
14	Columbia Univ	19	1.39	102	661	34.79
15	Mem Sloan Kettering Canc Ctr	19	1.39	89	2076	109.26
16	Natl Canc Ctr	19	1.39	65	402	21.16
17	Stanford Univ	19	1.39	47	1889	99.42
18	Univ Cambridge	19	1.39	37	777	40.89
19	Univ Utah	19	1.39	28	2008	105.68
20	Vanderbilt Univ	19	1.39	26	971	51.11

Table 5 Top 20 most productive authors in the research field of risk assessment for gastrointestinal neoplasms

Rank	Author	Publications	Percentage of 1371	Total citations	Average citation per paper
1	Syngal S	24	1.75	2273	94.71
2	Wang Y	18	1.31	178	9.89
3	Liu Y	15	1.09	195	13
4	Zhang Y	13	0.95	145	11.15
5	Li Y	12	0.88	82	6.83
6	Xu J	12	0.88	136	11.33
7	Orlando LA	11	0.8	137	12.45
8	Walter FM	10	0.73	228	22.8
9	Wang J	10	0.73	52	5.2
10	Zhang L	10	0.73	239	23.9
11	Emery JD	9	0.66	160	17.78
12	Li J	9	0.66	245	27.22
13	Li S	9	0.66	240	26.67
14	Li X	9	0.66	130	14.44
15	Lindor NM	9	0.66	874	97.11
16	Stoffel EM	9	0.66	601	66.78
17	Verma M	9	0.66	379	42.11
18	Wang X	9	0.66	430	47.78
19	Zhang J	9	0.66	43	4.78
20	Burt RW	8	0.58	1568	196

Table 6 Top 20 most productive cocite authors in the research field of risk assessment for gastrointestinal neoplasms

Rank	Cocite author	Citations	Centrality
1	Lynch HT	134	0.12
2	Vasen HFA	125	0.03
3	Hampel H	89	0.04
4	Giardiello FM	79	0.13
5	Jarvinen HJ	68	0.04
6	Umar A	65	0.05
7	Siegel RL	63	0.01
8	Berg AO	63	0.04
9	Bray F	56	0
10	Jemal A	55	0.03
11	Ferlay J	54	0.03
12	Syngal S	53	0.03
13	Kastrinos F	53	0.04
14	Boland CR	49	0.1
15	Rex DK	39	0.06
16	Chen SN	38	0.02
17	Easton DF	37	0.05
18	Aaltonen LA	37	0.17
19	Lindor NM	36	0.02
20	Gail MH	35	0.03

Table 7 Top 10 journals related to the research on risk assessment for gastrointestinal neoplasms

Rank	Journal	Countries	Count	IF (2021)	JCR (2021)	H-index	Total citations
1	Familial Cancer	Netherlands	27	2.45	Q3	11	387
2	Journal of Clinical Oncology	United States	22	50.717	Q1	18	2823
3	Cancer	United States	20	6.92	Q1	10	1092
4	Genetics in Medicine	United States	20	8.86	Q1	15	871
5	International Journal of Cancer	Switzerland	20	7.32	Q1	13	668
6	BMC Cancer	England	18	4.64	Q2	11	268
7	Journal of Genetic Counseling	United States	18	2.717	Q3	10	492
8	Cancer Epidemiology Biomarkers & Prevention	United States	16	4.09	Q2	11	363
9	Frontiers in Oncology	Switzerland	16	5.738	Q2	11	611
10	Diseases of The Colon & Rectum	United States	15	4.41	Q1	8	298

Table 8 Top 10 cocited journals related to the research on risk assessment for gastrointestinal neoplasms

Rank	Cocited Journal	Countries	Total citations	IF (2021)	JCR (2021)
1	Journal of Clinical Oncology	United States	2403	50.717	Q1
2	Cancer Research	United States	1687	13.31	Q1
3	Gastroenterology	United States	1669	33.88	Q1
4	New England Journal of Medicine	United States	1645	176.079	Q1
5	International Journal of Cancer	Switzerland	1121	7.32	Q1
6	Jama-Journal of The American Medical Association	United States	1070	157.335	Q1
7	GUT	England	939	31.79	Q1
8	Cancer Epidemiology Biomarkers & Prevention	United States	925	4.09	Q2
9	British Journal of Cancer	England	862	9.08	Q1
10	Lancet	England	830	202.731	Q1

Table 9 Top 10 cocited references concerning the research of risk assessment of gastrointestinal neoplasms

Title	First author	Journal	Year	IF (2021)	JCR (2021)	Citations
New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC	Vasen HFA	Gastroenterology	1999	33.88	Q1	74
Revised Bethesda Guidelines for Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) and Microsatellite Instability.	Umar A	Journal of The National Cancer Institute	2004	11.816	Q1	67
Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer	Jarvinen HJ	Gastroenterology	2000	33.88	Q1	59
The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)	Vasen HFA	Diseases of The Colon & Rectum	1991	4.41	Q1	49
A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: Meeting Highlights and Bethesda Guidelines	Rodriguezbigas MA	Journal of The National Cancer Institute	1997	11.816	Q1	46
A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer	Boland CR	Cancer Research	1998	13.31	Q1	42
Hereditary Colorectal Cancer	Lynch HT	New England Journal of Medicine	2003	176.079	Q1	42
Screening for the Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer)	Hampel H	New England Journal of Medicine	2005	176.079	Q1	41
Projecting Individualized Probabilities of Developing Breast Cancer for White Females Who Are Being Examined Annually	Gail MH	Journal of The National Cancer Institute	1989	11.816	Q1	40
Feasibility of Screening for Lynch Syndrome Among Patients With Colorectal Cancer	Hampel H	Journal of Clinical Oncology	2008	50.717	Q1	34

Table 10 The 20 most common keywords related to risk assessment for gastrointestinal neoplasms

Rank	Keywords	Total link strength	Frequency
1	Colorectal cancer	417	200
2	Risk assessment	411	169
3	Gastric cancer	168	77
4	Cancer	167	70
5	Lynch syndrome	162	63
6	Genetic testing	136	49
7	Colon cancer	102	45
8	Genetic counseling	131	44
9	Prognosis	108	44
10	Family history	117	38