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Contents Volume 32 Issue 27 July 21, 2026
Editorial
IGF2BP3 in gastric cancer: Unraveling an N6-methyladenosine-driven oncogenic axis for therapeutic targeting
Xue-Lian Luo, Li-Yang Dai, Ling-Yun Luo, Si-Bi Yin, Qi-Yuan Feng 
World J Gastroenterol 32(27):116347. Published online Jul 21, 2026. doi: 10.3748/wjg.116347
Opinion Review
Is metabolic dysfunction-associated steatotic liver disease truly irrelevant? Unmasking the heterogeneity and confounders in pancreatic cancer outcomes
Yi-Yuan Zheng, Tao-Ying Deng, Jian-Dong Cao, Yan-Hua Lin, Yu-Zi Jiang, Zhe-Kun Xiong 
World J Gastroenterol 32(27):119356. Published online Jul 21, 2026. doi: 10.3748/wjg.119356
Review
Metabolic memory in the gut: The microbiota-epigenetic crosstalk orchestrating obesity onset and novel therapeutic landscapes
Yun Liu, Yu-Jue Wang, Shuai-Yan Wang, Cong-Yi Xie, Mo Zhou, En-He Zhao, Xin-Yu Shen, Jing-Yan Pan, Bin Xu, Tian-Cheng Xu 
World J Gastroenterol 32(27):120135. Published online Jul 21, 2026. doi: 10.3748/wjg.120135
Retrospective Cohort Study
Clinical characteristics and treatment patterns of older and younger patients with inflammatory bowel disease
Fatih Kivrakoglu, Vedat Kilic, Mustafa Ergin, Harun Kucuk, Cagdas Erdogan, Ilhami Yuksel 
World J Gastroenterol 32(27):120681. Published online Jul 21, 2026. doi: 10.3748/wjg.120681
Retrospective Study
Machine learning-driven pathogen cluster analysis identifies high-risk subtypes of infected pancreatic necrosis in a multi-center cohort
Bai-Qi Liu, Ze-Fang Sun, Cai-Hong Ning, Jie Xiao, Di Wu, Chia-Yen Lin, Xiao-Yue Hong, Rong Guo, Lu Chen, Xin-Tong Cao, Ding-Cheng Shen, Geng-Wen Huang 
World J Gastroenterol 32(27):118717. Published online Jul 21, 2026. doi: 10.3748/wjg.118717
Clinical Trials Study
Artificial intelligence-based mucosa touch rate: A novel real-time quality control indicator for colonoscopy
Wen Chen, Meng Wu, Heng-Yu Wang, Hong-Bo Wu, Jie Li, Yu-Hao Sun, Fang Huang, Min Gao, Zhi-Hang Zhong, Yan-Min Wu, Lei Chen 
World J Gastroenterol 32(27):119276. Published online Jul 21, 2026. doi: 10.3748/wjg.119276
Observational Study
Non-alcoholic fatty liver disease fibrosis score is a useful tool for carotid atherosclerosis screening in patients with obstructive sleep apnea
Carlos Ernesto Fernández-García, Miguel Á Hernández-García, Beatriz Aldave-Orzáiz, Elena Ávalos Pérez-Urría, José M Muñoz, Alfonsi Friera, Carmelo García-Monzón, Pedro Landete, Águeda González-Rodríguez 
World J Gastroenterol 32(27):117715. Published online Jul 21, 2026. doi: 10.3748/wjg.117715
Basic Study
Contribution of the appendix to ulcerative colitis by supplying pathogenic immunoglobulin G-producing cells
Yusuke Izutani, Takayuki Ogino, Shuhei Sakakibara, Yosuke Kishi, Yu-Chen Liu, Yusuke Nakano, Akio Fukada, Yuki Sekido, Ryuichi Kuwahara, Takako Kihara, Mitsunobu Takeda, Tsuyoshi Hata, Atsushi Hamabe, Norikatsu Miyoshi, Mamoru Uemura, Hiroki Ikeuchi, Seiichi Hirota, Kiyoshi Takeda, Tsunekazu Mizushima, Daisuke Okuzaki, Yuichiro Doki, Hidetoshi Eguchi 
World J Gastroenterol 32(27):117897. Published online Jul 21, 2026. doi: 10.3748/wjg.117897
Kinetochore-associated protein 1 as a prognostic biomarker in gastric cancer: Integrative bioinformatics and experimental validation
You-Feng Li, Chun-Yan Weng, Mi Wang 
World J Gastroenterol 32(27):118071. Published online Jul 21, 2026. doi: 10.3748/wjg.118071
Gram-negative bacteria and endotoxins promote hepatocellular carcinoma progression through the recruitment of myeloid-derived suppressor cells
Yong Zhang, You-Lian Zhou, Xin Nie, Liang-Jie Zhang, Wei-Wei Xu, Jia-Qi Wang, Hai-Lan Zhao, Jing-Kui Xu, Jing Xu, Hao-Ming Xu, Jian-Hong Li, Wen-Qi Huang, Jing Yang, Yao-Xiang Yang, Qi Zhan, Yong Lin, Yu-Qiang Nie 
World J Gastroenterol 32(27):118794. Published online Jul 21, 2026. doi: 10.3748/wjg.118794
Hua-Zhuo-Jie-Du formula alleviates colitis-associated colorectal cancer via regulating phosphatidylinositol 3-kinase/protein kinase B signaling pathway
Shao-Pu Hu, Yan-Ru Cai, Yang Liu, Yu-Xi Guo, Xue-Mei Jia, Jian-Ming Jiang, Qian Yang 
World J Gastroenterol 32(27):119490. Published online Jul 21, 2026. doi: 10.3748/wjg.119490
Meta-Analysis
Performance of computer-aided diagnosis for colorectal sessile serrated lesions: A systematic review and meta-analysis
Song Zhang, Shi-Hang Wang, You-Dong Zhao, Jia-Hui Wei, Xiang-Yu Sui, Xin Li, Huan-Wei Zhang, Zhi-Yao Huang, Cheng-Long Wang, Hao Hu, Jing Zhang, Zhao-Shen Li, Sheng-Bing Zhao, Yu Bai 
World J Gastroenterol 32(27):118009. Published online Jul 21, 2026. doi: 10.3748/wjg.118009
Correspondence
Letter to the Editor: Not one disease - ethnic-specific mutational pathways redefine precision oncology in esophageal cancer
Rui-Jie Ming, Hua-Wen Liu 
World J Gastroenterol 32(27):116615. Published online Jul 21, 2026. doi: 10.3748/wjg.116615
Letter to the Editor: Tumor necrosis factor-α signaling and β-cell apoptosis in acute pancreatitis - integrating molecular mechanisms and metabolic implications
Lara Lizzi, Mara Massimi 
World J Gastroenterol 32(27):117268. Published online Jul 21, 2026. doi: 10.3748/wjg.117268
Letter to the Editor: Trimetazidine modulates gut microbiota-lipid metabolism axis: A novel avenue for anti-aging interventions
Hai-Bo Wu, Ting Chen, Yi Tian 
World J Gastroenterol 32(27):119545. Published online Jul 21, 2026. doi: 10.3748/wjg.119545
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