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Clinical Trials Study
Copyright: ©Author(s) 2026.
World J Gastroenterol. Jul 21, 2026; 32(27): 119276
Published online Jul 21, 2026. doi: 10.3748/wjg.119276
Table 1 Basic performance test
Targets
Test subset A (95%CI)
Test subset B (95%CI)
Sensitivity (%)98.07 (97.81, 98.33)100.00 (100.00, 100.00)
Precision (%)100.00 (100.00, 100.00)100.00 (100.00, 100.00)
Accuracy (%)99.03 (99.00, 99.06)100.00 (100.00, 100.00)
Table 2 Model generalization performance tests
Test content
Recall % (95%CI)
Precision % (95%CI)
Accuracy % (95%CI)
Ileocecal recognition generalization
The first time96.15 (96.05, 96.25)99.34 (99.13, 99.55)97.76 (97.27, 98.25)
The second time96.79 (96.34, 97.24)98.69 (98.33, 99.05)97.75 (97.52, 97.98)
The third time96.15 (95.89, 96.41)99.34 (98.93, 99.75)97.76 (97.11, 98.41)
Mucosa touch recognition generalization
The first time98.72 (98.39, 99.05)100.00 (100.00, 100.00)99.36 (99.03, 99.69)
The second time100.00 (100.00, 100.00)100.00 (100.00, 100.00)100.00 (100.00, 100.00)
The third time98.72 (98.43, 99.01)100.00 (100.00, 100.00)99.36 (99.00, 99.72)
Table 3 Factors that impact mucosa touch rate detection
Change factorIleocecal recognition
Mucosa touch recognition
Recall % (95%CI)
Precision % (95%CI)
Accuracy % (95%CI)
Recall % (95%CI)
Precision % (95%CI)
Accuracy % (95%CI)
Calculated test metrics for the test set of factors affecting the brightness
0.296.15 (95.87, 96.43)100.00 (100.00, 100.00)98.08 (97.90, 98.26)100.00 (100.00, 100.00)100.00 (100.00, 100.00)100.00 (100.00, 100.00)
0.496.15 (96.00, 96.03)98.04 (97.89, 98.19)97.12 (96.85, 97.39)100.00 (100.00, 100.00)98.11 (98.01, 98.21)99.04 (98.76, 99.32)
0.694.23 (94.14, 94.32)98.00 (97.95, 98.05)96.15 (95.88, 96.42)98.07 (97.88, 98.26)98.07 (97.47, 98.67)98.07 (96.89, 99.25)
0.894.23 (93.17, 95.29)96.08 (94.33, 97.83)95.19 (92.83, 97.55)96.15 (94.52, 97.78)98.04 (96.14, 99.94)97.12 (94.86, 99.38)
1.092.31 (90.21, 94.41)96.00 (93.68, 98.32)94.23 (92.35, 96.11)94.23 (91.36, 97.10)96.08 (92.89, 99.27)95.19 (93.68, 96.70)
1.292.31 (89.87, 94.75)96.00 (92.59, 99.41)94.23 (91.44, 97.02)94.23 (91.33, 97.13)94.23 (92.35, 96.11)94.23 (90.66, 97.80)
1.486.54 (83.77, 89.31)88.23 (82.99, 93.47)87.5 (85.44, 89.56)92.31 (88.75, 95.87)94.12 (90.33, 97.91)93.27 (89.71, 96.83)
1.619.23 (14.69, 23.77)58.82 (50.69, 66.95)52.88 (48.99, 56.77)42.31 (38.55, 46.07)50.00 (45.06, 54.94)50.00 (45.06, 54.94)
1.819.23 (14.69, 23.77)58.82 (50.69, 66.95)52.88 (48.99, 56.77)42.31 (38.55, 46.07)50.00 (45.06, 54.94)50.00 (45.06, 54.94)
2.019.23 (14.69, 23.77)58.82 (50.69, 66.95)52.88 (48.99, 56.77)42.31 (38.55, 46.07)50.00 (45.06, 54.94)50.00 (45.06, 54.94)
Calculated test metrics for the test set of contrast influencing factors
0.296.15 (93.77, 98.53)98.04 (97.33, 98.75)97.12 (96.55, 97.69)98.08 (96.47, 99.69)100.00 (100.00, 100.00)99.04 (98.15, 99.93)
0.498.08 (96.81, 99.35)98.08 (96.99, 99.17)98.08 (97.00, 99.16)100.00 (100.00, 100.00)100.00 (100.00, 100.00)100.00 (100.00, 100.00)
0.694.23 (92.65, 95.81)96.08 (94.33, 97.83)95.19 (92.69, 97.69)96.15 (94.87, 97.43)94.34 (91.58, 97.10)95.19 (93.67, 96.71)
0.892.31 (90.77, 93.85)94.12 (93.17, 95.07)93.27 (91.22, 95.32)94.23 (92.59, 95.87)96.08 (94.33, 97.83)95.19 (93.74, 96.64)
1.086.53 (81.79, 91.27)86.53 (83.44, 89.62)86.54 (84.65, 88.43)92.31 (90.11, 94.51)73.85 (70.33, 77.37)79.81 (75.99, 83.63)
1.286.53 (83.77, 89.29)78.95 (76.88, 81.02)81.73 (78.54, 84.92)92.31 (90.41, 94.21)73.85 (70.41, 77.29)79.81 (77.25, 82.37)
1.478.84 (76.38, 81.30)70.69 (67.89, 73.49)73.08 (71.21, 74.95)92.31 (89.76, 94.86)68.57 (65.71, 71.43)75.00 (72.99, 77.01)
1.675.00 (73.68, 76.32)67.24 (63.79, 70.69)69.23 (65.33, 73.13)88.46 (85.67, 91.25)63.89 (60.55, 67.23)69.23 (66.31, 72.15)
1.859.62 (57.22, 62.02)58.49 (57.71, 59.27)58.65 (54.99, 62.31)84.62 (81.67, 87.57)61.97 (59.43, 64.51)66.34 (64.58, 68.10)
2.048.08 (46.71, 49.45)42.37 (39.97, 44.77)41.35 (38.53, 44.17)76.92 (74.66, 79.18)55.56 (53.78, 57.34)57.69 (56.43, 58.95)
Calculated test metrics for the test set of rotational change influencing factors
-30°98.07 (97.99, 98.15)98.07 (97.99, 98.15)98.07 (97.99, 98.15)98.07 (97.99, 98.15)100.00 (100.00, 100.00)99.04 (98.08, 100.00)
-60°96.15 (95.21, 97.09)98.04 (97.32, 98.76)97.12 (95.69, 98.55)96.15 (94.87, 97.43)100.00 (100.00, 100.00)98.08 (96.87, 99.29)
-90°98.07 (96.87, 99.27)100.00 (100.00, 100.00)99.03 (98.06,100.00)100.00 (100.00, 100.00)100.00 (100.00, 100.00)100.00 (100.00, 100.00)
-120°98.07 (97.66, 98.48)98.07 (97.99, 98.15)98.07 (98.00, 98.14)100.00 (100.00, 100.00)98.11 (98.03, 98.19)99.04 (98.08, 100.00)
-150°94.23 (92.66, 95.80)96.08 (94.77, 97.39)95.19 (94.15, 96.23)96.15 (95.21, 97.09)100.00 (100.00, 100.00)98.08 (97.99, 98.17)
-180°98.07 (97.88, 98.26)100.00 (100.00, 100.00)99.03 (98.06, 100.00)100.00 (100.00, 100.00)100.00 (100.00, 100.00)100.00 (100.00, 100.00)
-210°96.15 (94.77, 97.53)98.04 (96.58, 99.50)97.12 (94.99, 99.25)96.15 (95.37, 96.93)100.00 (100.00, 100.00)98.08 (98.01, 98.15)
-240°94.23 (92.63, 95.83)96.08 (95.77, 96.39)95.19 (94.15, 96.23)98.07 (97.16, 98.98)100.00 (100.00, 100.00)99.04 (98.08, 100.00)
-270°98.07 (97.19, 98.95)100.00 (100.00, 100.00)99.03 (98.06, 100.00)100.00 (100.00, 100.00)98.11 (98.03, 98.19)99.04 (98.99, 99.09)
-300°94.23 (92.41, 96.05)96.08 (95.88, 96.28)95.19 (93.77, 96.61)98.07 (98.00, 98.14)100.00 (100.00, 100.00)99.04 (98.89, 99.19)
-330°96.15 (94.58, 97.72)98.04 (96.59, 99.49)97.12 (95.88, 98.36)96.15 (94.79, 97.51)100.00 (100.00, 100.00)98.08 (97.99, 98.17)
Table 4 Comparison of baseline demographic data characteristics between the control group and experimental group, mean ± SD/n (%)

Control group (n = 1500)
Experimental group (n = 1366)
P value
Sex> 0.05
Male700 (46.67)649 (47.51)
Female800 (53.33)717 (52.49)
Age, years49.68 ± 13.850.66 ± 13.47> 0.05
Examination purpose> 0.05
Symptomatic988 (65.87)913 (66.84)
Health check-up375 (23.80)328 (24.01)
Disease monitoring107 (53.33)98 (53.33)
Abnormal test results30 (7.13)27 (1.98)
Table 5 Overall polyp detection rate and adenoma detection rate in the clinical validation phase
GroupSample sizePDR
ADR
P value (PDR)
P value (ADR)
n (%)
(95%CI)
n (%)
(95%CI)
Experimental1366699 (51.17)(48.32, 54.02)147 (10.76)(7.35, 14.17)< 0.001> 0.05
Control1500601 (40.07)(34.87, 45.27)141 (9.40)(6.89, 11.91)
Table 6 Polyp detection rate and adenoma detection rate by seniority and group
Endoscopist groupSubgroupSample sizePDR
ADR
P value (PDR)
P value (ADR)
n (%)
(95%CI)
n (%)
(95%CI)
High-seniorityControl750329 (43.87)(39.75, 47.99)84 (11.20)(7.46, 14.96)< 0.05> 0.05
Experimental750372 (49.60)(46.25, 52.95)92 (12.27)(8.73, 15.81)
Low-seniorityControl750272 (36.27)(33.82, 38.72)57 (7.60)(4.38, 10.82)< 0.001> 0.05
Experimental616346 (56.17)(50.36, 61.98)62 (10.06)(6.37, 13.75)
Table 7 Polyp detection rate and adenoma detection rate by age subgroup
Age subgroupSubgroupPDR
ADR
P value (PDR)
P value (ADR)
n (%)
(95%CI)
n (%)
(95%CI)
< 40 yearsControl (n = 320)68 (21.25)(17.65, 24.85)25 (7.81)(5.20, 10.42)< 0.01< 0.05
Experimental (n = 290)89 (30.69)(26.71, 34.67)39 (13.45)(10.24, 16.66)
40-60 yearsControl (n = 790)293 (37.09)(33.85, 40.33)118 (14.94)(11.37, 18.51)< 0.001< 0.001
Experimental (n = 720)350 (48.61)(45.70, 51.52)168 (23.33)(19.64, 27.02)
> 60 yearsControl (n = 390)162 (41.54)(39.45, 43.63)67 (17.18)(16.40, 17.96)< 0.001< 0.001
Experimental (n = 356)183 (51.40)(46.65, 56.15)88 (24.72)(20.98, 28.46)


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