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Contents Volume 7 Issue 2 March 26, 2015

Editorial

SIRT1 and stem cells: In the forefront with cardiovascular disease, neurodegeneration and cancer

Kenneth Maiese

World J Stem Cells 7(2):235-242. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.235

Abstract (1432) | Core Tip (1221) | Full Article (HTML) (5528) | Figures (1-1) (379) | Full Article (PDF)-893K (618) | Peer-Review Report-94K (270) | Answering Reviewers-64K (305) | Received: 11/02/2014 | Revised: 12/10/2014 | Accepted: 01/19/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (44) | Total Visits (13074) | Similar Articles (259) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Review

Substrates for clinical applicability of stem cells

Sanjar Enam, Sha Jin

World J Stem Cells 7(2):243-252. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.243

Abstract (1271) | Core Tip (1221) | Full Article (HTML) (3763) | Tables (1-1) (514) | Full Article (PDF)-1020K (464) | Peer-Review Report-102K (393) | Answering Reviewers-65K (236) | Received: 07/17/2014 | Revised: 10/23/2014 | Accepted: 12/19/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (8) | Total Visits (11612) | Similar Articles (16) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Hematopoietic stem cell-derived adipocytes and fibroblasts in the tumor microenvironment

Ying Xiong, Lindsay T McDonald, Dayvia L Russell, Ryan R Kelly, Katie R Wilson, Meenal Mehrotra, Adam C Soloff, Amanda C LaRue

World J Stem Cells 7(2):253-265. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.253

Abstract (1808) | Core Tip (1593) | Full Article (HTML) (10865) | Figures (1-3) (1165) | Full Article (PDF)-2626K (918) | Peer-Review Report-119K (414) | Answering Reviewers-33K (360) | Received: 07/29/2014 | Revised: 11/08/2014 | Accepted: 12/01/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (43) | Total Visits (23166) | Similar Articles (2) | Timeline of Article Publication (6) | Article Quality Tracking (0) | Cite |

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Role of nanotopography in the development of tissue engineered 3D organs and tissues using mesenchymal stem cells

Shima Salmasi, Deepak M Kalaskar, Wai-Weng Yoon, Gordon W Blunn, Alexander M Seifalian

World J Stem Cells 7(2):266-280. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.266

Abstract (1339) | Core Tip (1135) | Full Article (HTML) (6517) | Figures (1-8) (552) | Tables (1-2) (452) | Full Article (PDF)-6363K (778) | Peer-Review Report-99K (305) | Answering Reviewers-63K (301) | Received: 07/29/2014 | Revised: 10/13/2014 | Accepted: 12/10/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (42) | Total Visits (15850) | Similar Articles (150) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Evaluating alternative stem cell hypotheses for adult corneal epithelial maintenance

John D West, Natalie J Dorà, J Martin Collinson

World J Stem Cells 7(2):281-299. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.281

Abstract (1626) | Core Tip (1948) | Full Article (HTML) (9183) | Figures (1-6) (730) | Tables (1-2) (489) | Full Article (PDF)-7887K (863) | Peer-Review Report-111K (337) | Answering Reviewers-20K (433) | Received: 07/29/2014 | Revised: 09/26/2014 | Accepted: 10/16/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (63) | Total Visits (22733) | Similar Articles (37) | Timeline of Article Publication (3) | Article Quality Tracking (0) | Cite |

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Imprinted Zac1 in neural stem cells

Guillaume Daniel, Udo Schmidt-Edelkraut, Dietmar Spengler, Anke Hoffmann

World J Stem Cells 7(2):300-314. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.300

Abstract (1238) | Core Tip (1304) | Full Article (HTML) (4469) | Figures (1-3) (599) | Full Article (PDF)-1205K (596) | Peer-Review Report-76K (277) | Answering Reviewers-128K (278) | Received: 07/25/2014 | Revised: 09/24/2014 | Accepted: 11/19/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (6) | Total Visits (14712) | Similar Articles (13) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Induced pluripotent stem cells: Mechanisms, achievements and perspectives in farm animals

Dharmendra Kumar, Thirumala R Talluri, Taruna Anand, Wilfried A Kues

World J Stem Cells 7(2):315-328. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.315

Abstract (1469) | Core Tip (1413) | Full Article (HTML) (9810) | Figures (1-4) (459) | Tables (1-2) (996) | Full Article (PDF)-2975K (886) | Peer-Review Report-85K (450) | Answering Reviewers-64K (371) | Received: 07/15/2014 | Revised: 08/19/2014 | Accepted: 12/17/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (43) | Total Visits (20011) | Similar Articles (24) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Cardiac disease modeling using induced pluripotent stem cell-derived human cardiomyocytes

Patrizia Dell’Era, Patrizia Benzoni, Elisabetta Crescini, Matteo Valle, Er Xia, Antonella Consiglio, Maurizio Memo

World J Stem Cells 7(2):329-342. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.329

Abstract (1839) | Core Tip (1206) | Full Article (HTML) (6664) | Figures (1-1) (461) | Tables (1-2) (417) | Full Article (PDF)-1268K (714) | Peer-Review Report-121K (315) | Answering Reviewers-85K (248) | Received: 07/29/2014 | Revised: 10/27/2014 | Accepted: 11/19/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (39) | Total Visits (15465) | Similar Articles (0) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Stem cell therapy in inflammatory bowel disease: A promising therapeutic strategy?

Ana I Flores, Gonzalo J Gómez-Gómez, Ángeles Masedo-González, M Pilar Martínez-Montiel

World J Stem Cells 7(2):343-351. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.343

Abstract (1338) | Core Tip (1207) | Full Article (HTML) (4995) | Tables (1-3) (461) | Full Article (PDF)-981K (591) | Peer-Review Report-125K (283) | Answering Reviewers-147K (299) | Received: 07/29/2014 | Revised: 09/24/2014 | Accepted: 11/10/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (27) | Total Visits (13788) | Similar Articles (663) | Timeline of Article Publication (1) | Authors Evaluation (2) | Article Quality Tracking (0) | Cite |

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“Second-generation” stem cells for cardiac repair

Alberto Núñez García, Ricardo Sanz-Ruiz, María Eugenia Fernández Santos, Francisco Fernández-Avilés

World J Stem Cells 7(2):352-367. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.352

Abstract (1822) | Core Tip (1117) | Full Article (HTML) (3950) | Tables (1-1) (480) | Full Article (PDF)-1121K (514) | Peer-Review Report-104K (248) | Answering Reviewers-96K (250) | Received: 08/06/2014 | Revised: 09/26/2014 | Accepted: 11/10/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (18) | Total Visits (11373) | Similar Articles (87) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Mesenchymal stem cells as a therapeutic tool to treat sepsis

Eleuterio Lombardo, Tom van der Poll, Olga DelaRosa, Wilfried Dalemans

World J Stem Cells 7(2):368-379. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.368

Abstract (1536) | Core Tip (1256) | Full Article (HTML) (5759) | Tables (1-1) (518) | Full Article (PDF)-986K (663) | Peer-Review Report-81K (296) | Answering Reviewers-57K (336) | Received: 09/29/2014 | Revised: 11/13/2014 | Accepted: 12/17/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (87) | Total Visits (16973) | Similar Articles (100) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Transplantation of stem cell-derived astrocytes for the treatment of amyotrophic lateral sclerosis and spinal cord injury

Charles Nicaise, Dinko Mitrecic, Aditi Falnikar, Angelo C Lepore

World J Stem Cells 7(2):380-398. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.380

Abstract (1339) | Core Tip (1508) | Full Article (HTML) (7752) | Tables (1-2) (851) | Full Article (PDF)-1138K (981) | Peer-Review Report-130K (266) | Answering Reviewers-135K (276) | Received: 07/29/2014 | Revised: 10/07/2014 | Accepted: 11/19/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (60) | Total Visits (17104) | Similar Articles (174) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Tooth-derived stem cells: Update and perspectives

Miki Taketomi Saito, Karina Gonzales Silvério, Márcio Zaffalon Casati, Enilson Antonio Sallum, Francisco Humberto Nociti Jr

World J Stem Cells 7(2):399-407. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.399

Abstract (1443) | Core Tip (1195) | Full Article (HTML) (7427) | Figures (1-1) (604) | Tables (1-2) (444) | Full Article (PDF)-1013K (816) | Peer-Review Report-128K (326) | Answering Reviewers-64K (349) | Received: 07/19/2014 | Revised: 10/22/2014 | Accepted: 11/10/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (78) | Total Visits (16296) | Similar Articles (53) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Could cancer and infection be adverse effects of mesenchymal stromal cell therapy?

Martha L Arango-Rodriguez, Fernando Ezquer, Marcelo Ezquer, Paulette Conget

World J Stem Cells 7(2):408-417. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.408

Abstract (1171) | Core Tip (1160) | Full Article (HTML) (4138) | Figures (1-1) (482) | Full Article (PDF)-1014K (514) | Peer-Review Report-79K (237) | Answering Reviewers-86K (305) | Received: 07/12/2014 | Revised: 10/01/2014 | Accepted: 11/10/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (22) | Total Visits (10913) | Similar Articles (385) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Mitochondria as therapeutic targets for cancer stem cells

In Sung Song, Jeong Yu Jeong, Seung Hun Jeong, Hyoung Kyu Kim, Kyung Soo Ko, Byoung Doo Rhee, Nari Kim, Jin Han

World J Stem Cells 7(2):418-427. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.418

Abstract (1253) | Core Tip (1258) | Full Article (HTML) (6713) | Figures (1-1) (418) | Tables (1-2) (431) | Full Article (PDF)-1113K (961) | Peer-Review Report-124K (430) | Answering Reviewers-107K (382) | Received: 07/27/2014 | Revised: 09/25/2014 | Accepted: 11/03/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (55) | Total Visits (15923) | Similar Articles (70) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Vital roles of stem cells and biomaterials in skin tissue engineering

Abu Bakar Mohd Hilmi, Ahmad Sukari Halim

World J Stem Cells 7(2):428-436. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.428

Abstract (1417) | Core Tip (1304) | Full Article (HTML) (6288) | Figures (1-3) (500) | Tables (1-1) (978) | Full Article (PDF)-2665K (630) | Peer-Review Report-94K (326) | Answering Reviewers-77K (286) | Received: 07/31/2014 | Revised: 09/29/2014 | Accepted: 10/27/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (49) | Total Visits (16235) | Similar Articles (8) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Neural differentiation from embryonic stem cells in vitro: An overview of the signaling pathways

Jen-Hua Chuang, Li-Chu Tung, Yenshou Lin

World J Stem Cells 7(2):437-447. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.437

Abstract (1532) | Core Tip (1420) | Full Article (HTML) (11260) | Figures (1-1) (829) | Full Article (PDF)-1106K (1084) | Peer-Review Report-90K (402) | Answering Reviewers-19K (352) | Received: 07/17/2014 | Revised: 09/12/2014 | Accepted: 12/17/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (74) | Total Visits (21228) | Similar Articles (66) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Importance of the stem cell microenvironment for ophthalmological cell-based therapy

Peng-Xia Wan, Bo-Wen Wang, Zhi-Chong Wang

World J Stem Cells 7(2):448-460. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.448

Abstract (1355) | Core Tip (1297) | Full Article (HTML) (5034) | Figures (1-1) (781) | Full Article (PDF)-1115K (535) | Peer-Review Report-103K (277) | Answering Reviewers-81K (328) | Received: 07/27/2014 | Revised: 09/17/2014 | Accepted: 10/29/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (32) | Total Visits (13540) | Similar Articles (48) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Minireviews

Using induced pluripotent stem cells as a tool for modelling carcinogenesis

Emma L Curry, Mohammad Moad, Craig N Robson, Rakesh Heer

World J Stem Cells 7(2):461-469. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.461

Abstract (1289) | Core Tip (1306) | Full Article (HTML) (7237) | Figures (1-2) (492) | Tables (1-1) (1036) | Full Article (PDF)-1022K (678) | Peer-Review Report-114K (376) | Answering Reviewers-18K (328) | Received: 08/14/2014 | Revised: 10/29/2014 | Accepted: 11/03/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (36) | Total Visits (17000) | Similar Articles (35) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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CD271 as a marker to identify mesenchymal stem cells from diverse sources before culture

María Álvarez-Viejo, Yolanda Menéndez-Menéndez, Jesús Otero-Hernández

World J Stem Cells 7(2):470-476. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.470

Abstract (1494) | Core Tip (1387) | Full Article (HTML) (7891) | Tables (1-1) (496) | Full Article (PDF)-900K (2866) | Peer-Review Report-120K (297) | Answering Reviewers-20K (434) | Received: 08/01/2014 | Revised: 10/28/2014 | Accepted: 12/01/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (138) | Total Visits (18159) | Similar Articles (150) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Adult stem cells in neural repair: Current options, limitations and perspectives

Eric Domingos Mariano, Manoel Jacobsen Teixeira, Suely Kazue Nagahashi Marie, Guilherme Lepski

World J Stem Cells 7(2):477-482. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.477

Abstract (1391) | Core Tip (1399) | Full Article (HTML) (6243) | Tables (1-1) (487) | Full Article (PDF)-804K (564) | Peer-Review Report-113K (240) | Answering Reviewers-61K (261) | Received: 07/29/2014 | Revised: 10/22/2014 | Accepted: 11/03/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (24) | Total Visits (14312) | Similar Articles (92) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Development of cancer-initiating cells and immortalized cells with genomic instability

Ken-ichi Yoshioka, Yuko Atsumi, Hitoshi Nakagama, Hirobumi Teraoka

World J Stem Cells 7(2):483-489. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.483

Abstract (1385) | Core Tip (1116) | Full Article (HTML) (5306) | Figures (1-2) (413) | Full Article (PDF)-996K (672) | Peer-Review Report-92K (309) | Answering Reviewers-168K (297) | Received: 07/23/2014 | Revised: 09/29/2014 | Accepted: 11/10/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (23) | Total Visits (13095) | Similar Articles (3) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Adult stem-like cells in kidney

Keiichi Hishikawa, Osamu Takase, Masahiro Yoshikawa, Taro Tsujimura, Masaomi Nangaku, Tsuyoshi Takato

World J Stem Cells 7(2):490-494. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.490

Abstract (1232) | Core Tip (1136) | Full Article (HTML) (6092) | Tables (1-1) (476) | Full Article (PDF)-806K (547) | Peer-Review Report-117K (370) | Answering Reviewers-65K (320) | Received: 07/29/2014 | Revised: 10/31/2014 | Accepted: 12/10/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (14) | Total Visits (17394) | Similar Articles (36) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Niche interactions in epidermal stem cells

Hye-Ryung Choi, Sang-Young Byun, Soon-Hyo Kwon, Kyoung-Chan Park

World J Stem Cells 7(2):495-501. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.495

Abstract (1336) | Core Tip (1273) | Full Article (HTML) (6146) | Figures (1-4) (451) | Full Article (PDF)-1205K (597) | Peer-Review Report-96K (315) | Answering Reviewers-64K (311) | Received: 08/11/2014 | Revised: 10/22/2014 | Accepted: 11/03/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (41) | Total Visits (13690) | Similar Articles (0) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Neural stem cells could serve as a therapeutic material for age-related neurodegenerative diseases

Sarawut Suksuphew, Parinya Noisa

World J Stem Cells 7(2):502-511. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.502

Abstract (1429) | Core Tip (1495) | Full Article (HTML) (18623) | Figures (1-1) (527) | Tables (1-1) (451) | Full Article (PDF)-1194K (690) | Peer-Review Report-103K (388) | Answering Reviewers-83K (374) | Received: 07/28/2014 | Revised: 09/18/2014 | Accepted: 10/27/2014 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (40) | Total Visits (28029) | Similar Articles (17) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Molecular mechanism of extrinsic factors affecting anti-aging of stem cells

Tzyy Yue Wong, Mairim Alexandra Solis, Ying-Hui Chen, Lynn Ling-Huei Huang

World J Stem Cells 7(2):512-520. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.512

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Basic Study

Mesenchymal stem cells and collagen patches for anterior cruciate ligament repair

Benjamin Gantenbein, Neha Gadhari, Samantha CW Chan, Sandro Kohl, Sufian S Ahmad

World J Stem Cells 7(2):521-534. Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.521

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