Neural stem cells could serve as a therapeutic material for age-related neurodegenerative diseases

Table 1 Characteristics and conventional treatment for Alzheimer’s, Parkinson’s and Huntington’s diseases

Disease	Characteristics	Treatment	Ref.
Alzheimer’s	Memory impairment	Medications:	[9,15,16,26,27,30]
	Impaired reasoning and handling of complex tasks, poor judgment	Cholinesterase inhibitors
	Changes in personality, behavior, or comportment	NMDA antagonist
		Non-medicals
		Psychological supports
Parkinson’s	Motor symptoms	1 Medications	[1,6-8,23-25]
	(1) Rest tremor	Dopaminergics:
	(2) Bradykinesia	(1) Levodopa
	(3) Rigidity	(2) Ergot dopamine agonists
	(4) Loss of postural reflexes	(3) Non-ergot dopamine agonists
	Non-motor symptoms	Non-dopaminergic:
	(1) Autonomic dysfunction	(1) COMT inhibitors
	(2) Cognitive/neurobehavioral abnormalities	(2) MAO-B inhibitors
	(3) Sleep disorders	2 Non-medicals
	(4) Sensory abnormalities such as anosmia, paresthesias and pain	Ablative lesions
		Deep brain stimulation
Huntington’s	Choreiform movement	Medications	[17,18,20,33,36]
	Cognitive impairment	Symptomatic agents
	Behavior and psychological disorders

NMDA: N-methyl-D-aspartate receptor; COMT: Catechol-O-methyltransferase; MAO: Monoamine oxidase.