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Contents Volume 27 Issue 23 June 21, 2021

Editorial

Pain management in chronic pancreatitis incorporating safe opioid practices: Challenge accepted

Ishani Shah, Sunil G Sheth, Darshan J Kothari

World J Gastroenterol 27(23):3142-3147. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3142

Abstract (1401) | Core Tip (1018) | Full Article (HTML) (7600) | Figures (1-1) (702) | Full Article (PDF)-940K (673) | Audio-103K (16) | Peer-Review Report-224K (248) | Answering Reviewers-165K (252) | Received: 03/17/2021 | Revised: 04/15/2021 | Accepted: 05/21/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (14) | Total Visits (16213) | Similar Articles (105) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Evidence Review

Pancreatitis and pancreatic cancer: A case of the chicken or the egg

Devica S Umans, Sanne A Hoogenboom, Noor J Sissingh, Selma J Lekkerkerker, Robert C Verdonk, Jeanin E van Hooft

World J Gastroenterol 27(23):3148-3157. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3148

Abstract (1244) | Core Tip (1052) | Full Article (HTML) (6802) | Figures (1-4) (621) | Tables (1-1) (604) | Full Article (PDF)-2588K (852) | Audio-2029K (16) | Peer-Review Report-188K (252) | Answering Reviewers-157K (250) | Received: 01/25/2021 | Revised: 03/13/2021 | Accepted: 05/08/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (36) | Total Visits (17121) | Similar Articles (165) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Review

Pancreatic adenocarcinoma: A review of recent paradigms and advances in epidemiology, clinical diagnosis and management

Nikhil Gupta, Raghav Yelamanchi

World J Gastroenterol 27(23):3158-3181. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3158

Abstract (1826) | Core Tip (1508) | Full Article (HTML) (7240) | Figures (1-4) (588) | Tables (1-4) (941) | Full Article (PDF)-1373K (1420) | Audio-451K (23) | Peer-Review Report-216K (296) | Answering Reviewers-53K (262) | Received: 01/22/2021 | Revised: 03/03/2021 | Accepted: 05/21/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (34) | Total Visits (19265) | Similar Articles (27) | Timeline of Article Publication (3) | Authors Evaluation (3) | Article Quality Tracking (1) | Cite |

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Silencing hepatitis B virus covalently closed circular DNA: The potential of an epigenetic therapy approach

Prashika Singh, Dylan Kairuz, Patrick Arbuthnot, Kristie Bloom

World J Gastroenterol 27(23):3182-3207. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3182

Abstract (1225) | Core Tip (1634) | Full Article (HTML) (8301) | Figures (1-2) (630) | Tables (1-1) (1111) | Full Article (PDF)-2377K (931) | Audio-867K (21) | Peer-Review Report-150K (273) | Answering Reviewers-363K (266) | Received: 01/29/2021 | Revised: 03/23/2021 | Accepted: 05/07/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (19) | Total Visits (18549) | Similar Articles (1881) | Timeline of Article Publication (0) | Authors Evaluation (2) | Article Quality Tracking (2) | Cite |

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COVID-19-associated diarrhea

Klara Megyeri, Áron Dernovics, Zaid I I Al-Luhaibi, András Rosztóczy

World J Gastroenterol 27(23):3208-3222. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3208

Abstract (1534) | Core Tip (1081) | Full Article (HTML) (10910) | Figures (1-1) (719) | Full Article (PDF)-1900K (891) | Audio-3029K (16) | Peer-Review Report-167K (246) | Answering Reviewers-128K (261) | Received: 02/04/2021 | Revised: 03/19/2021 | Accepted: 05/20/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (46) | Total Visits (21654) | Similar Articles (760) | Timeline of Article Publication (0) | Authors Evaluation (3) | Article Quality Tracking (1) | Cite |

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Assessment of liver disease in patients with chronic hepatitis C and unhealthy alcohol use

Daniel Fuster, Xavier García-Calvo, Paola Zuluaga, Ferran Bolao, Robert Muga

World J Gastroenterol 27(23):3223-3237. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3223

Abstract (1127) | Core Tip (1100) | Full Article (HTML) (4293) | Tables (1-2) (540) | Full Article (PDF)-938K (636) | Audio-476K (29) | Peer-Review Report-261K (259) | Answering Reviewers-207K (283) | Received: 02/09/2021 | Revised: 03/11/2021 | Accepted: 05/10/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (13369) | Similar Articles (47) | Timeline of Article Publication (0) | Authors Evaluation (3) | Article Quality Tracking (1) | Cite |

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Minireviews

Clinical indicators for progression of nonalcoholic steatohepatitis to cirrhosis

Tasur Kumar Seen, Muntazir Sayed, Muhammad Bilal, Jonathan Vincent Reyes, Priyanka Bhandari, Vennis Lourdusamy, Ahmed Al-khazraji, Umer Syed, Yasar Sattar, Raghav Bansal

World J Gastroenterol 27(23):3238-3248. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3238

Abstract (1314) | Core Tip (1060) | Full Article (HTML) (4918) | Figures (1-2) (545) | Tables (1-3) (969) | Full Article (PDF)-993K (653) | Audio-437K (25) | Peer-Review Report-213K (253) | Answering Reviewers-395K (297) | Received: 10/24/2020 | Revised: 12/06/2020 | Accepted: 04/20/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (19) | Total Visits (14684) | Similar Articles (430) | Timeline of Article Publication (2) | Article Quality Tracking (2) | Cite |

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Update on the management and treatment of viral hepatitis

Patricia Holanda Almeida, Celso E L Matielo, Lilian A Curvelo, Rodrigo A Rocco, Guilherme Felga, Bianca Della Guardia, Yuri L Boteon

World J Gastroenterol 27(23):3249-3261. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3249

Abstract (1209) | Core Tip (1723) | Full Article (HTML) (9998) | Figures (1-1) (1109) | Tables (1-1) (549) | Full Article (PDF)-1131K (958) | Audio-1763K (26) | Peer-Review Report-292K (297) | Answering Reviewers-144K (289) | Received: 01/18/2021 | Revised: 03/11/2021 | Accepted: 04/22/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (50) | Total Visits (20054) | Similar Articles (24) | Timeline of Article Publication (2) | Authors Evaluation (3) | Article Quality Tracking (1) | Cite |

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Large-duct pattern invasive adenocarcinoma of the pancreas–a variant mimicking pancreatic cystic neoplasms: A minireview

Hiroki Sato, Andrew Scott Liss, Yusuke Mizukami

World J Gastroenterol 27(23):3262-3278. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3262

Abstract (1763) | Core Tip (1643) | Full Article (HTML) (5145) | Figures (1-4) (1053) | Tables (1-3) (510) | Full Article (PDF)-9649K (798) | Audio-1980K (13) | Peer-Review Report-240K (282) | Answering Reviewers-325K (285) | Received: 01/28/2021 | Revised: 03/09/2021 | Accepted: 05/17/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (16) | Total Visits (18075) | Similar Articles (51) | Timeline of Article Publication (2) | Authors Evaluation (4) | Article Quality Tracking (1) | Cite |

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Chronic hepatitis B in pregnant women: Current trends and approaches

Maria Belopolskaya, Viktor Avrutin, Olga Kalinina, Alexander Dmitriev, Denis Gusev

World J Gastroenterol 27(23):3279-3289. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3279

Abstract (1072) | Core Tip (1352) | Full Article (HTML) (8386) | Tables (1-7) (1084) | Full Article (PDF)-883K (763) | Audio-498K (13) | Peer-Review Report-155K (226) | Answering Reviewers-104K (253) | Received: 01/28/2021 | Revised: 03/10/2021 | Accepted: 04/22/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (24) | Total Visits (17305) | Similar Articles (181) | Timeline of Article Publication (0) | Authors Evaluation (8) | Article Quality Tracking (2) | Cite |

(0) | (0) | (0) | (0) | Open

Viscoelastic tests in liver disease: where do we stand now?

Alina Buliarca, Adelina Horhat, Tudor Mocan, Rares Craciun, Bogdan Procopet, Zeno Sparchez

World J Gastroenterol 27(23):3290-3302. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3290

Abstract (1159) | Core Tip (1015) | Full Article (HTML) (6912) | Figures (1-2) (540) | Tables (1-2) (486) | Full Article (PDF)-1292K (923) | Audio-1060K (22) | Peer-Review Report-169K (275) | Answering Reviewers-82K (251) | Received: 02/01/2021 | Revised: 03/17/2021 | Accepted: 05/20/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (29) | Total Visits (16139) | Similar Articles (0) | Timeline of Article Publication (1) | Authors Evaluation (6) | Article Quality Tracking (1) | Cite |

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Gastrointestinal involvement in paediatric COVID-19 — from pathogenesis to clinical management: A comprehensive review

Carmelina Calitri, Ilaria Fumi, Maria Giovanna Ignaccolo, Elena Banino, Stefania Benetti, Maria Maddalena Lupica, Francesca Fantone, Mariella Pace, Franco Garofalo

World J Gastroenterol 27(23):3303-3316. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3303

Abstract (1473) | Core Tip (1405) | Full Article (HTML) (6197) | Figures (1-1) (525) | Full Article (PDF)-1175K (676) | Audio-525K (20) | Peer-Review Report-166K (207) | Answering Reviewers-74K (226) | Received: 01/28/2021 | Revised: 03/10/2021 | Accepted: 05/24/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (35) | Total Visits (15672) | Similar Articles (783) | Timeline of Article Publication (2) | Article Quality Tracking (1) | Cite |

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Can control of gut microbiota be a future therapeutic option for inflammatory bowel disease?

Atsushi Nishida, Kyohei Nishino, Keitaro Sakai, Yuji Owaki, Yoshika Noda, Hirotsugu Imaeda

World J Gastroenterol 27(23):3317-3326. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3317

Abstract (963) | Core Tip (881) | Full Article (HTML) (7266) | Figures (1-1) (573) | Tables (1-1) (530) | Full Article (PDF)-1258K (937) | Audio-553K (29) | Peer-Review Report-321K (281) | Answering Reviewers-90K (299) | Received: 03/17/2021 | Revised: 04/23/2021 | Accepted: 05/07/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (48) | Total Visits (16631) | Similar Articles (663) | Timeline of Article Publication (1) | Authors Evaluation (4) | Article Quality Tracking (1) | Cite |

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Basic Study

Oncogenic tuftelin 1 as a potential molecular-targeted for inhibiting hepatocellular carcinoma growth

Meng-Na Wu, Wen-Jie Zheng, Wen-Xin Ye, Li Wang, Ying Chen, Jie Yang, Deng-Fu Yao, Min Yao

World J Gastroenterol 27(23):3327-3341. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3327

Abstract (1074) | Core Tip (1023) | Article Highlights (1062) | Full Article (HTML) (3949) | Figures (1-6) (569) | Tables (1-3) (492) | Full Article (PDF)-11348K (519) | Audio-681K (28) | Peer-Review Report-247K (218) | Answering Reviewers-250K (233) | Received: 12/14/2020 | Revised: 01/06/2021 | Accepted: 05/18/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (5) | Total Visits (15414) | Similar Articles (1896) | Timeline of Article Publication (2) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Conditioned secretome of adipose-derived stem cells improves dextran sulfate sodium-induced colitis in mice

Seunghun Lee, Jeonghoon Heo, Eun-Kyung Ahn, Jae Hyun Kim, Young-Ho Kim, Hee-Kyung Chang, Sang-Joon Lee, Jongsik Kim, Seun-Ja Park

World J Gastroenterol 27(23):3342-3356. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3342

Abstract (1498) | Core Tip (1448) | Article Highlights (1080) | Full Article (HTML) (4002) | Figures (1-5) (531) | Tables (1-1) (514) | Full Article (PDF)-3114K (563) | Audio-873K (19) | Peer-Review Report-220K (224) | Answering Reviewers-79K (209) | Received: 02/04/2021 | Revised: 03/05/2021 | Accepted: 05/19/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (8) | Total Visits (15734) | Similar Articles (102) | Timeline of Article Publication (2) | Article Quality Tracking (1) | Cite |

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Case Control Study

Pancreatic enzymes and abdominal adipose tissue distribution in new-onset prediabetes/diabetes after acute pancreatitis

Juyeon Ko, Loren Skudder-Hill, Jaelim Cho, Sakina H Bharmal, Maxim S Petrov

World J Gastroenterol 27(23):3357-3371. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3357

Abstract (1506) | Core Tip (885) | Article Highlights (1337) | Full Article (HTML) (4047) | Figures (1-3) (553) | Tables (1-3) (498) | Full Article (PDF)-1238K (595) | Audio-679K (21) | Peer-Review Report-223K (208) | Answering Reviewers-98K (220) | Received: 01/29/2021 | Revised: 04/14/2021 | Accepted: 06/07/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (15) | Total Visits (15956) | Similar Articles (419) | Timeline of Article Publication (2) | Authors Evaluation (4) | Article Quality Tracking (1) | Cite |

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Retrospective Cohort Study

Effect of type 2 diabetic mellitus in the prognosis of acute-on-chronic liver failure patients in China

Rui-Min Lai, Tian-Bin Chen, Yu-Hai Hu, Gui Wu, Qi Zheng

World J Gastroenterol 27(23):3372-3385. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3372

Abstract (1102) | Core Tip (1012) | Article Highlights (1126) | Full Article (HTML) (3128) | Figures (1-3) (541) | Tables (1-3) (1034) | Full Article (PDF)-1694K (485) | Audio-1343K (40) | Peer-Review Report-176K (220) | Answering Reviewers-151K (241) | Received: 01/28/2021 | Revised: 04/14/2021 | Accepted: 05/20/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (14) | Total Visits (16503) | Similar Articles (351) | Timeline of Article Publication (3) | Article Quality Tracking (2) | Cite |

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Observational Study

Preliminary prospective study of real-time post-gastrectomy glycemic fluctuations during dumping symptoms using continuous glucose monitoring

Motonari Ri, Souya Nunobe, Satoshi Ida, Naoki Ishizuka, Shinichiro Atsumi, Rie Makuuchi, Koshi Kumagai, Manabu Ohashi, Takeshi Sano

World J Gastroenterol 27(23):3386-3395. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3386

Abstract (1280) | Core Tip (833) | Article Highlights (1040) | Full Article (HTML) (3563) | Figures (1-2) (892) | Tables (1-3) (527) | Full Article (PDF)-1557K (468) | Audio-859K (20) | Peer-Review Report-314K (230) | Answering Reviewers-128K (216) | Received: 12/25/2020 | Revised: 04/14/2021 | Accepted: 05/22/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (8) | Total Visits (14872) | Similar Articles (86) | Timeline of Article Publication (1) | Authors Evaluation (3) | Article Quality Tracking (1) | Cite |

(0) | (0) | (0) | (0) | Open

Prospective Study

Real-world treatment patterns and disease control over one year in patients with inflammatory bowel disease in Brazil

Ligia Yukie Sassaki, Sender J Miszputen, Roberto Luiz Kaiser Junior, Wilson R Catapani, Mauro Bafutto, António S Scotton, Cyrla Zaltman, Julio Pinheiro Baima, Hagata S Ramos, Mikaell Alexandre Gouvea Faria, Carolina D Gonçalves, Isabella Miranda Guimaraes, Cristina Flores, Heda M B S Amarante, Rodrigo Bremer Nones, José Miguel Luz Parente, Murilo Moura Lima, Júlio Maria Chebli, Maria de Lourdes Abreu Ferrari, Julia F Campos, Maria G P Sanna, Odery Ramos, Rogério Serafim Parra, Jose J R da Rocha, Omar Feres, Marley R Feitosa, Rosana Fusaro Caratin, Juliana Tosta Senra, Genoile Oliveira Santana

World J Gastroenterol 27(23):3396-3412. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3396

Abstract (1345) | Core Tip (1049) | Article Highlights (1132) | Full Article (HTML) (4322) | Figures (1-4) (570) | Tables (1-3) (495) | Full Article (PDF)-1703K (642) | Audio-1412K (44) | Peer-Review Report-221K (235) | Answering Reviewers-225K (235) | Received: 03/08/2021 | Revised: 04/17/2021 | Accepted: 05/27/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (4) | Total Visits (18112) | Similar Articles (707) | Timeline of Article Publication (1) | Authors Evaluation (2) | Article Quality Tracking (1) | Cite |

(1) | (0) | (0) | (0) | Open

Systematic Reviews

Local ablation of pancreatic tumors: State of the art and future perspectives

Vincenza Granata, Roberta Grassi, Roberta Fusco, Andrea Belli, Raffaele Palaia, Gianpaolo Carrafiello, Vittorio Miele, Roberto Grassi, Antonella Petrillo, Francesco Izzo

World J Gastroenterol 27(23):3413-3428. Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3413

Abstract (1027) | Core Tip (1027) | Article Highlights (1047) | Full Article (HTML) (4924) | Figures (1-4) (502) | Tables (1-4) (595) | Full Article (PDF)-4416K (704) | Audio-392K (13) | Peer-Review Report-658K (254) | Answering Reviewers-101K (270) | Received: 03/07/2021 | Revised: 03/28/2021 | Accepted: 05/08/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (43) | Total Visits (15296) | Similar Articles (595) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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