Review
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 21, 2021; 27(23): 3158-3181
Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3158
Pancreatic adenocarcinoma: A review of recent paradigms and advances in epidemiology, clinical diagnosis and management
Nikhil Gupta, Raghav Yelamanchi
Nikhil Gupta, Raghav Yelamanchi, Department of Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, Delhi 110001, India
Author contributions: Gupta N performed the literature review and critically reviewed the manuscript; Yelamanchi R performed the literature review and drafted the manuscript; all authors read and approved the final manuscript.
Conflict-of-interest statement: None of the authors has any conflict of interest or financial ties to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Nikhil Gupta, FACS, FRCS (Gen Surg), Professor, Surgeon, Department of Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, BKS Marg, Delhi 110001, India. nikhil_ms26@yahoo.co.in
Received: January 22, 2021
Peer-review started: January 22, 2021
First decision: February 28, 2021
Revised: March 3, 2021
Accepted: May 21, 2021
Article in press: May 21, 2021
Published online: June 21, 2021
Processing time: 146 Days and 11.8 Hours
Core Tip

Core Tip: Pancreatic cancer is one of the dreaded malignancies for both patients and clinicians. This narrative review highlights the newer trends and achievements in the epidemiology, etiopathogenesis, screening, diagnosis and management of pancreatic adenocarcinoma (PDA). It is intended to improve the readers’ understanding of the latest updates of PDA, which may help to trigger new research ideas and make better management decisions. Newer screening and diagnostic techniques will help in diagnosing the patients in early stages and prognosticate them better. The newer discoveries in drugs and management protocols will help increase the survival and quality of life of the patients.