Case Control Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 21, 2021; 27(23): 3357-3371
Published online Jun 21, 2021. doi: 10.3748/wjg.v27.i23.3357
Pancreatic enzymes and abdominal adipose tissue distribution in new-onset prediabetes/diabetes after acute pancreatitis
Juyeon Ko, Loren Skudder-Hill, Jaelim Cho, Sakina H Bharmal, Maxim S Petrov
Juyeon Ko, Loren Skudder-Hill, Jaelim Cho, Sakina H Bharmal, Maxim S Petrov, School of Medicine, University of Auckland, Auckland 1142, New Zealand
Author contributions: Ko J, Skudder-Hill L, Cho J, and Bharmal SH collected data; Ko J wrote the manuscript; Ko J, Skudder-Hill L, Cho J, Bharmal SH, and Petrov MS reviewed the manuscript; Petrov MS conceived and supervised the study.
Institutional review board statement: The study was approved by the Health and Disability Ethics Committee (New Zealand).
Informed consent statement: All study participants or their legal guardians provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: The authors have no conflict of interest.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Maxim S Petrov, MD, MPH, PhD, Professor, School of Medicine, University of Auckland, 28 Park Avenue, Auckland 1142, New Zealand. m.petrov@auckland.ac.nz
Received: January 29, 2021
Peer-review started: January 29, 2021
First decision: April 5, 2021
Revised: April 14, 2021
Accepted: June 7, 2021
Article in press: June 7, 2021
Published online: June 21, 2021
Processing time: 140 Days and 3.6 Hours
Core Tip

Core Tip: Intra-pancreatic fat deposition and visceral fat volume are significantly inversely associated with circulating levels of pancreatic amylase in individuals with new-onset prediabetes/diabetes after acute pancreatitis, but not in healthy individuals or those with type 2 prediabetes/diabetes mellitus.