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Contents Volume 22 Issue 23 June 21, 2016

Topic Highlight

Fibroblasts, an inconspicuous but essential player in colon cancer development and progression

Naofumi Mukaida, Soichiro Sasaki

World J Gastroenterol 22(23):5301-5316. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5301

Abstract (1805) | Core Tip (1539) | Full Article (HTML) (9758) | Figures (1-4) (798) | Tables (1-1) (567) | Full Article (PDF)-3329K (1315) | Audio-2744K (35) | Peer-Review Report-88K (363) | Answering Reviewers-115K (303) | Received: 03/16/2016 | Revised: 04/22/2016 | Accepted: 05/23/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (41) | Total Visits (25472) | Similar Articles (0) | Timeline of Article Publication (0) | Authors Evaluation (3) | Cite |

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MicroRNAs: Novel immunotherapeutic targets in colorectal carcinoma

Xiang Li, Jing Nie, Qian Mei, Wei-Dong Han

World J Gastroenterol 22(23):5317-5331. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5317

Abstract (1618) | Core Tip (1625) | Full Article (HTML) (8668) | Figures (1-2) (609) | Full Article (PDF)-1880K (927) | Audio-1544K (40) | Peer-Review Report-87K (355) | Answering Reviewers-153K (386) | Received: 03/24/2016 | Revised: 04/23/2016 | Accepted: 05/04/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (47) | Total Visits (23863) | Similar Articles (81) | Timeline of Article Publication (0) | Cite |

(0) | (0) | (0) | (0) | Open

Treatment dilemmas of cetuximab combined with chemotherapy for metastatic colorectal cancer

Feng Wen, Qiu Li

World J Gastroenterol 22(23):5332-5341. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5332

Abstract (1734) | Core Tip (1517) | Full Article (HTML) (7552) | Figures (1-3) (853) | Tables (1-1) (616) | Full Article (PDF)-1120K (980) | Audio-1061K (40) | Peer-Review Report-81K (342) | Answering Reviewers-102K (445) | Received: 03/21/2016 | Revised: 05/02/2016 | Accepted: 05/23/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (19) | Total Visits (22459) | Similar Articles (1385) | Timeline of Article Publication (0) | Cite |

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Basic Study

Tumor-specific expression of shVEGF and suicide gene as a novel strategy for esophageal cancer therapy

Ting Liu, Hai-Jun Wu, Yu Liang, Xu-Jun Liang, Hui-Chao Huang, Yan-Zhong Zhao, Qing-Chuan Liao, Ya-Qi Chen, Ai-Min Leng, Wei-Jian Yuan, Gui-Ying Zhang, Jie Peng, Yong-Heng Chen

World J Gastroenterol 22(23):5342-5352. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5342

Abstract (1796) | Core Tip (1368) | Full Article (HTML) (4581) | Figures (1-6) (554) | Full Article (PDF)-1240K (622) | Audio-3216K (26) | Peer-Review Report-98K (299) | Answering Reviewers-193K (365) | Received: 12/02/2015 | Revised: 04/06/2016 | Accepted: 04/20/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (20) | Total Visits (17084) | Similar Articles (164) | Timeline of Article Publication (0) | Cite |

(0) | (0) | (0) | (0) | Open

Long-pulse gastric electrical stimulation protects interstitial cells of Cajal in diabetic rats via IGF-1 signaling pathway

Hai Li, Yan Chen, Shi Liu, Xiao-Hua Hou

World J Gastroenterol 22(23):5353-5363. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5353

Abstract (1546) | Core Tip (1580) | Full Article (HTML) (4443) | Figures (1-7) (643) | Tables (1-1) (610) | Full Article (PDF)-2949K (537) | Audio-835K (26) | Peer-Review Report-151K (304) | Answering Reviewers-425K (390) | Received: 03/01/2016 | Revised: 04/14/2016 | Accepted: 05/04/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (13) | Total Visits (17744) | Similar Articles (18) | Timeline of Article Publication (0) | Cite |

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MicroRNA-548a-5p promotes proliferation and inhibits apoptosis in hepatocellular carcinoma cells by targeting Tg737

Ge Zhao, Ting Wang, Qi-Ke Huang, Meng Pu, Wei Sun, Zhuo-Chao Zhang, Rui Ling, Kai-Shan Tao

World J Gastroenterol 22(23):5364-5373. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5364

Abstract (1358) | Core Tip (1348) | Full Article (HTML) (5306) | Figures (1-4) (553) | Full Article (PDF)-1464K (600) | Audio-725K (39) | Peer-Review Report-142K (332) | Answering Reviewers-231K (419) | Received: 02/14/2016 | Revised: 04/04/2016 | Accepted: 05/04/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (20) | Total Visits (18110) | Similar Articles (324) | Timeline of Article Publication (0) | Cite |

(0) | (0) | (0) | (0) | Open

Curcumin improves regulatory T cells in gut-associated lymphoid tissue of colitis mice

Hai-Mei Zhao, Rong Xu, Xiao-Ying Huang, Shao-Min Cheng, Min-Fang Huang, Hai-Yang Yue, Xin Wang, Yong Zou, Ai-Ping Lu, Duan-Yong Liu

World J Gastroenterol 22(23):5374-5383. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5374

Abstract (1423) | Core Tip (1497) | Full Article (HTML) (5827) | Figures (1-4) (814) | Full Article (PDF)-1985K (747) | Audio-1440K (65) | Peer-Review Report-80K (309) | Answering Reviewers-72K (328) | Received: 02/27/2016 | Revised: 03/29/2016 | Accepted: 04/15/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (44) | Total Visits (20349) | Similar Articles (48) | Timeline of Article Publication (0) | Cite |

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Case Control Study

Adjuvant sorafenib after heptectomy for Barcelona Clinic Liver Cancer-stage C hepatocellular carcinoma patients

Feng Xia, Li-Li Wu, Wan-Yee Lau, Hong-Bo Huan, Xu-Dong Wen, Kuan-Sheng Ma, Xiao-Wu Li, Ping Bie

World J Gastroenterol 22(23):5384-5392. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5384

Abstract (1754) | Core Tip (1444) | Full Article (HTML) (6771) | Figures (1-1) (558) | Tables (1-5) (544) | Full Article (PDF)-990K (917) | Audio-2216K (50) | Peer-Review Report-117K (306) | Answering Reviewers-362K (346) | Received: 03/04/2016 | Revised: 03/31/2016 | Accepted: 04/20/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (46) | Total Visits (19232) | Similar Articles (1909) | Timeline of Article Publication (0) | Cite |

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Retrospective Cohort Study

Genomic change in hepatitis B virus associated with development of hepatocellular carcinoma

Danbi Lee, Heather Lyu, Young-Hwa Chung, Jeong A Kim, Priya Mathews, Elizabeth Jaffee, Lei Zheng, Eunsil Yu, Young Joo Lee, Soo Hyung Ryu

World J Gastroenterol 22(23):5393-5399. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5393

Abstract (1459) | Core Tip (1307) | Full Article (HTML) (4610) | Figures (1-4) (533) | Tables (1-3) (512) | Full Article (PDF)-1309K (876) | Audio-991K (35) | Peer-Review Report-101K (304) | Answering Reviewers-171K (334) | Received: 02/02/2016 | Revised: 03/21/2016 | Accepted: 04/07/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (12) | Total Visits (17429) | Similar Articles (2243) | Timeline of Article Publication (0) | Cite |

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Retrospective Study

Last line therapy with sorafenib in colorectal cancer: A retrospective analysis

Ksenia Martchenko, Irene Schmidtmann, Thomas Thomaidis, Verena Thole, Peter R Galle, Marc Becker, Markus Möhler, Thomas C Wehler, Carl C Schimanski

World J Gastroenterol 22(23):5400-5405. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5400

Abstract (1504) | Core Tip (1361) | Full Article (HTML) (3606) | Figures (1-2) (524) | Tables (1-4) (519) | Full Article (PDF)-977K (959) | Audio-746K (30) | Peer-Review Report-78K (268) | Answering Reviewers-170K (376) | Received: 08/18/2015 | Accepted: 01/30/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (8) | Total Visits (17155) | Similar Articles (1203) | Timeline of Article Publication (0) | Cite |

(0) | (0) | (0) | (0) | Open

Association of HER2 status with prognosis in gastric cancer patients undergoing R0 resection: A large-scale multicenter study in China

Guo-Shuang Shen, Jiu-Da Zhao, Jun-Hui Zhao, Xin-Fu Ma, Feng Du, Jie Kan, Fa-Xiang Ji, Fei Ma, Fang-Chao Zheng, Zi-Yi Wang, Bing-He Xu

World J Gastroenterol 22(23):5406-5414. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5406

Abstract (1475) | Core Tip (1338) | Full Article (HTML) (5281) | Figures (1-2) (535) | Tables (1-3) (507) | Full Article (PDF)-1331K (688) | Audio-1743K (37) | Peer-Review Report-79K (354) | Answering Reviewers-243K (316) | Received: 01/20/2016 | Revised: 05/11/2016 | Accepted: 05/23/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (17) | Total Visits (19440) | Similar Articles (1294) | Timeline of Article Publication (3) | Cite |

(0) | (0) | (0) | (0) | Open

Clinical Trials Study

Intestinal-borne dermatoses significantly improved by oral application of Escherichia coli Nissle 1917

Elina Manzhalii, Daniel Hornuss, Wolfgang Stremmel

World J Gastroenterol 22(23):5415-5421. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5415

Abstract (1802) | Core Tip (1779) | Full Article (HTML) (9069) | Figures (1-3) (712) | Tables (1-3) (563) | Full Article (PDF)-1049K (1068) | Audio-826K (274) | Peer-Review Report-83K (358) | Answering Reviewers-31K (353) | Received: 01/07/2016 | Accepted: 05/04/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (54) | Total Visits (24389) | Similar Articles (0) | Timeline of Article Publication (0) | Cite |

(0) | (0) | (0) | (0) | Open

Observational Study

Endocan-expressing microvessel density as a prognostic factor for survival in human gastric cancer

Yuan Chang, Wei Niu, Pei-Long Lian, Xian-Qiang Wang, Zhi-Xin Meng, Yi Liu, Rui Zhao

World J Gastroenterol 22(23):5422-5429. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5422

Abstract (1482) | Core Tip (1406) | Full Article (HTML) (4408) | Figures (1-3) (581) | Tables (1-4) (508) | Full Article (PDF)-1342K (670) | Audio-1116K (36) | Peer-Review Report-86K (314) | Answering Reviewers-35K (311) | Received: 03/13/2016 | Revised: 04/12/2016 | Accepted: 05/04/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (35) | Total Visits (18035) | Similar Articles (1410) | Timeline of Article Publication (1) | Cite |

(0) | (0) | (0) | (0) | Open

Randomized Clinical Trial

Randomized study of lafutidine vs lansoprazole in patients with mild gastroesophageal reflux disease

Ryuta Takenaka, Hiroyuki Okada, Seiji Kawano, Yoshinori Komazawa, Fumiya Yoshinaga, Shinji Nagata, Masafumi Inoue, Hirohisa Komatsu, Seiji Onogawa, Yoshinori Kushiyama, Shinichi Mukai, Hiroko Todo, Hideharu Okanobu, Noriaki Manabe, Shinji Tanaka, Ken Haruma, Yoshikazu Kinoshita

World J Gastroenterol 22(23):5430-5435. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5430

Abstract (1651) | Core Tip (1437) | Full Article (HTML) (5410) | Figures (1-6) (528) | Tables (1-1) (525) | Full Article (PDF)-990K (822) | Audio-383K (43) | Peer-Review Report-80K (289) | Answering Reviewers-143K (309) | Received: 02/14/2016 | Revised: 04/17/2016 | Accepted: 05/23/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (19628) | Similar Articles (111) | Timeline of Article Publication (0) | Cite |

(0) | (0) | (0) | (0) | Open

Meta-Analysis

Efficacy and adverse events of cold vs hot polypectomy: A meta-analysis

Mikihiro Fujiya, Hiroki Sato, Nobuhiro Ueno, Aki Sakatani, Kazuyuki Tanaka, Tatsuya Dokoshi, Shugo Fujibayashi, Yoshiki Nomura, Shin Kashima, Takuma Gotoh, Junpei Sasajima, Kentaro Moriichi, Jiro Watari, Yutaka Kohgo

World J Gastroenterol 22(23):5436-5444. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5436

Abstract (1522) | Core Tip (1476) | Full Article (HTML) (6051) | Figures (1-3) (594) | Tables (1-2) (553) | Full Article (PDF)-1003K (823) | Audio-1404K (36) | Peer-Review Report-78K (320) | Answering Reviewers-154K (323) | Received: 01/29/2016 | Revised: 04/04/2016 | Accepted: 05/23/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (45) | Total Visits (17755) | Similar Articles (1) | Timeline of Article Publication (1) | Cite |

(0) | (0) | (0) | (0) | Open

Nonbismuth concomitant quadruple therapy for Helicobacter pylori eradication in Chinese regions: A meta-analysis of randomized controlled trials

Lien-Chieh Lin, Tzu-Herng Hsu, Kuang-Wei Huang, Ka-Wai Tam

World J Gastroenterol 22(23):5445-5453. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5445

Abstract (1688) | Core Tip (1560) | Full Article (HTML) (4761) | Figures (1-3) (515) | Tables (1-2) (540) | Full Article (PDF)-1017K (962) | Audio-606K (28) | Peer-Review Report-94K (401) | Answering Reviewers-30K (386) | Received: 03/15/2016 | Revised: 04/08/2016 | Accepted: 05/04/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (11) | Total Visits (17363) | Similar Articles (0) | Timeline of Article Publication (0) | Cite |

(0) | (0) | (0) | (0) | Open

Case Report

Endoscopic en bloc resection of an exophytic gastrointestinal stromal tumor with suction excavation technique

Hyuk Soon Choi, Hoon Jai Chun, Kyoung-Oh Kim, Eun Sun Kim, Bora Keum, Yoon-Tae Jeen, Hong Sik Lee, Chang Duck Kim

World J Gastroenterol 22(23):5454-5458. Published online Jun 21, 2016. doi: 10.3748/wjg.v22.i23.5454

Abstract (1648) | Core Tip (1380) | Full Article (HTML) (4112) | Figures (1-8) (580) | Full Article (PDF)-1038K (691) | Audio-821K (38) | Peer-Review Report-97K (374) | Answering Reviewers-165K (345) | Received: 02/01/2016 | Revised: 04/01/2016 | Accepted: 05/04/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (4) | Total Visits (16224) | Similar Articles (69) | Timeline of Article Publication (0) | Cite |

(0) | (0) | (0) | (0) | Open

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