Baishideng Publishing Group

Zhao YC, Che JN, Zhang YQ, Luo NN, Wang DX, Wang ZJ, Zhang WZ, Ma J, Cao XP, Wen X. Acupuncture and moxibustion for postoperative gastrointestinal disorders: An efficacy analysis. World J Gastrointest Surg 2026; 18(4): 115200

"The submission system of the World Journal of Radiology is user-friendly and efficient. The peer review process was rigorous yet ..." [Read more]

"The submission system of the World Journal of Radiology is user-friendly and efficient. The peer review process was rigorous yet constructive, with reviewers providing detailed and insightful comments that significantly improved our manuscript. The editorial handling was professional and timely. We greatly appreciate the reviewers' expertise and the editorial team's dedication, which enhanced the quality of our work. " [Collapse]

Fan JX, Jiang YP, Yao MQ. Adult ileocolic intussusception caused by a terminal ileal lipoma: A case report. World J Radiol 2026; 18(4): 120706

"We would like to express our complete satisfaction with WJG’s credibility and peer review process. The journal's peer-review process ..." [Read more]

"We would like to express our complete satisfaction with WJG’s credibility and peer review process. The journal's peer-review process is efficient and objective, which has helped us improve our manuscript. The publication workflow is efficient, and the editorial team demonstrates exceptional responsibility and professionalism. Thank you and the reviewers for the thorough review and valuable suggestions regarding our manuscript. " [Collapse]

Qi Y, Ma L, Zhang Y, Liu Y, Su M, Cai TT, Wang M, Sun KW. Insights into the pathogenic roles and targeted therapy of neutrophil extracellular traps in inflammatory bowel disease. World J Gastroenterol 2026; 32(17): 119419

"We greatly appreciate the dedicated efforts of all editors, reviewers, and publishing staff who contributed to our manuscript. From ..." [Read more]

"We greatly appreciate the dedicated efforts of all editors, reviewers, and publishing staff who contributed to our manuscript. From the initial editorial screening to the rigorous peer review, language polishing, and final production, every step was handled with professionalism and care. The entire publication process proved to be smooth, transparent, and highly satisfactory. We especially value the constructive feedback from the reviewers, which significantly improved our work. Thank you all for your hard work and support. " [Collapse]

Zhu JY, Tie J, Xia YF, Wang GC, Zhuge YZ, Wu H, Zhu XL, Xue H, Xu J, Zhang F, Zhao LH, Huang GJ, Zhang MY, Li Z, Wei B, Li PJ, Wang Z, Wu W, Chen C, Tang CW, Zhang CQ. Impact of rebleeding after transjugular intrahepatic portosystemic shunt on liver-related death based on liver function categories. World J Gastroenterol 2026; 32(17): 116867

"The authors would like to express their sincere gratitude to the editorial team of World Journal of Gastroenterology for their ..." [Read more]

"The authors would like to express their sincere gratitude to the editorial team of World Journal of Gastroenterology for their professionalism and support throughout the review process. We are deeply thankful to the anonymous reviewers for their insightful comments and constructive suggestions, which significantly improved the quality of our manuscript. Special thanks are extended to our colleagues at Benha Teaching Hospital and Suez University for their invaluable assistance. We also wish to acknowledge all participating patients for their trust and cooperation. This work was the result of genuine team effort, and we are grateful to everyone who contributed to its completion. " [Collapse]

Semeya AA, Makled WA, Elnagdy MA, Elgamal R, Othman AAA. Helicobacter pylori eradication and the prevention of peptic ulcer bleeding and cardiovascular disease progression in chronic aspirin users. World J Gastroenterol 2026; 32(17): 117544

"I was very satisfied with the entire process at World Journal of Radiology. This is a reputable journal with a professional workflow ..." [Read more]

"I was very satisfied with the entire process at World Journal of Radiology. This is a reputable journal with a professional workflow and prompt actions that did not cause any inconveniences. It should be noted that the editor responded promptly and positively, thereby providing additional motivation for the author to complete all procedures within the established framework. The process of peer review deserves particular attention, as it was constructive, contributing to the improvement of the manuscript by pointing out its flaws and recommending solutions. In addition, I would like to note that communication with the office was effective and timely. When I faced difficulties during revisions and proofs, all my requests were promptly answered and implemented. Thus, my work with World Journal of Radiology can be considered satisfactory since it represents a reliable and professionally managed journal adhering to high academic standards and providing appropriate author assistance. " [Collapse]

Chauhan A, Sharma S, Mishra A, Pathak A, Mittal KK. Study of displayed radiation dose and size-specific dose estimate from computed tomography brain examinations in accordance to head sizes. World J Radiol 2026; 18(4): 119450

"We are very satisfied with the entire publication process. Special thanks to the editor for the efficient and professional handling ..." [Read more]

"We are very satisfied with the entire publication process. Special thanks to the editor for the efficient and professional handling of our manuscript. We also deeply appreciate the anonymous reviewers, whose insightful and constructive comments significantly improved the quality and clarity of our work. It has been a genuine pleasure to publish in this journal, and we thank the entire editorial team for their support. " [Collapse]

Ni CX, Xu JJ. From local eradication to immune priming: Paradigm shift of hyperthermic intraperitoneal chemotherapy in gastric cancer therapy. World J Gastroenterol 2026; 32(17): 118346

"It was a great experience to write an invited article for the World Journal of Methodology. The article was on the physiological basis ..." [Read more]

"It was a great experience to write an invited article for the World Journal of Methodology. The article was on the physiological basis and the benefits of yoga. The review, revision, and editing helped in a great manner to improve the article. I express my sincere gratitude. I hope that the article will throw light into the scientific basis of yoga and the precautions needed in yogic practices. " [Collapse]

Unnithan AKA. Comprehensive review on the benefits and physiological basis of yoga. World J Methodol 2026; 16(2): 114072

"The authors sincerely thank the Editor and reviewers for their constructive feedback, which significantly improved the manuscript. ..." [Read more]

"The authors sincerely thank the Editor and reviewers for their constructive feedback, which significantly improved the manuscript. The peer-review process was efficient, fair, and transparent. We also appreciate the editorial office for their prompt communication and support throughout submission, revision, and publication. Overall, the process was smooth, professional, and well-coordinated. " [Collapse]

Chowdhury U, Mahajan AA, Kavitha MS, Rajendran RL, Gangadaran P, Ahn BC. Letter to the Editor: Magnetic resonance imaging-based deep learning radiomics for preoperative risk stratification in pediatric hepatoblastoma. World J Radiol 2026; 18(4): 118196

"We highly appreciate the professional and efficient peer review process of World Journal of Psychiatry. The reviewers’ comments were ..." [Read more]

"We highly appreciate the professional and efficient peer review process of World Journal of Psychiatry. The reviewers’ comments were constructive and insightful, which greatly helped us improve the quality and clarity of the manuscript. The journal offers a valuable platform for sharing high‑quality research findings in psychiatry, with a rigorous yet fair evaluation standard. We are satisfied with the overall experience and strongly recommend this journal to colleagues in the field. " [Collapse]

Ji YJ, Chen XC, Zheng Q, Liu Q, Zhang CY, Zhang TT, Li LJ. Implicit cognition tests for the prediction of suicide risk of non-suicidal self-injury in individuals: A systematic review. World J Psychiatry 2026; 16(3): 113825

"Thank you for the opportunity to publish our work in your esteemed journal. We had an outstanding experience with the process of ..." [Read more]

"Thank you for the opportunity to publish our work in your esteemed journal. We had an outstanding experience with the process of publishing. The processing of manuscript was done in a transparent manner. The reviewers comments and suggestions were very helpful in the revision which greatly improved the quality of the manuscript. Thank you once again for the opportunity. " [Collapse]

Marrapu S, Kumar R, Bhushan D, Kumar S, Kumar A, Priyadarshi RN, Anand U. Open-label randomized controlled study of salt-restricted vs salt-unrestricted diet in patients with cirrhosis with hyponatremia. World J Methodol 2026; 16(2): 112692

"The publication process took some time, but as this was an invited submission, it was understandable. Overall, the experience was ..." [Read more]

"The publication process took some time, but as this was an invited submission, it was understandable. Overall, the experience was satisfactory. It may still be helpful for the journal to streamline timelines where possible to support timely publication and further improve the author experience. Overall, I am more or less satisfied with the process. " [Collapse]

Chapra A, Ata F, Abdellatif A, Nofal M, Daniyal A, Mohammad Younus A, Shah JZ, Rasul K. Incidence and clinical course of immune checkpoint inhibitor-related cardiac adverse events: A descriptive study from the Middle East. World J Clin Cases 2026; 14(9): 118187

"It took considerable time to publish, although this was an invited submission, which partly mitigates concern. Nevertheless, the ..." [Read more]

"It took considerable time to publish, although this was an invited submission, which partly mitigates concern. Nevertheless, the editorial process would benefit from improved efficiency. Reducing publication timelines could enhance author experience and ensure timely dissemination of findings, ultimately strengthening the journal’s impact and relevance within the academic community overall. " [Collapse]

Ata F, Khan AA, Mohammad Nofal MZ, Abdelmahmuod EA, Fawad R, Al Mohanadi D, Dabbous Z. Improving diagnostic accuracy of 72-hour supervised fasting test for hypoglycemia evaluation: A quality improvement project. World J Methodol 2026; 16(2): 115150

"It took considerable time to publish, although this was an invited submission, which partly mitigates concern. Nevertheless, the ..." [Read more]

Ata F, Khan HA, Kashif A, Khan AA, Fawad R, Younas HW, Ahmed B, Javed H. Clinical insights into levothyroxine overdose: A systematic review. World J Methodol 2026; 16(2): 111025

"I would like to thank the editors of the World Journal of Methodology; the concept of this kind of journal is not often seen within ..." [Read more]

"I would like to thank the editors of the World Journal of Methodology; the concept of this kind of journal is not often seen within other publishers. Researchers need to share their experience with certain methodological studies and will be happy to have their journal included in the same scope as their work. " [Collapse]

Mekkodathil A, El-Menyar A, Rizoli S, Al-Thani H. Electrolyte-derived clinical indices in traumatic brain injury: A narrative review. World J Methodol 2026; 16(2): 111570

"Thank you for your invaluable support throughout the submission, revision, and publication process of our article. Your constructive ..." [Read more]

"Thank you for your invaluable support throughout the submission, revision, and publication process of our article. Your constructive feedback, attention to detail, and prompt communication significantly enhanced the quality and clarity of our manuscript. We deeply appreciate your professionalism, guidance, and dedication, which played a crucial role in the successful completion and publication of our work. " [Collapse]

Kalamara TV, Andreikos DA, Dodos K, Georgiou E, Fotakopoulos G, Foroglou N, Kapoukranidou D, Georgakopoulou VE. MicroRNAs as diagnostic and prognostic biomarkers in chemotherapy-induced peripheral neuropathy: A systematic review. World J Clin Oncol 2026; 17(4): 117460

"Thank you to the editorial team for the efficient organization and to the peer reviewers for their professional input. The peer-review ..." [Read more]

"Thank you to the editorial team for the efficient organization and to the peer reviewers for their professional input. The peer-review process was rigorous, the review timeline was reasonable, and the revision suggestions provided by the reviewers were specific and constructive, significantly enhancing the scientific quality and clarity of the manuscript. The editorial team responded promptly during communication, and the high transparency of the process facilitated the smooth progression of revisions. We look forward to future collaborations and also suggest further shortening the notification period during the external review stage. Overall, we are satisfied with this review experience " [Collapse]

Wen B, Wang QY, Li L, Zhang JG. Precision targeting of pathological angiogenesis in liver cirrhosis: Molecular mechanisms and therapeutic translation challenges. World J Hepatol 2026; 18(4): 114955

"Thank you for providing me with this valuable publication opportunity. I highly recognize and affirm the academic credibility and ..." [Read more]

"Thank you for providing me with this valuable publication opportunity. I highly recognize and affirm the academic credibility and standardized operation of this journal. The peer review process is very impartial, rigorous, efficient and constructive. Professional reviewers put forward targeted suggestions to optimize my manuscript. I am satisfied with the overall service and will continue to submit my research papers to this journal in the future. " [Collapse]

Zhou KB, Nie L, Wang ML, Xiao DH, Zhang HY, Yang X, Liao DF, Yang XF. Human umbilical cord mesenchymal stem cells ameliorate liver metabolism in diabetic rats with metabolic-associated fatty liver disease. World J Stem Cells 2025; 17(5): 105266

"The manuscript followed a thorough submission and guideline process and the submission platform was very easy to follow. The peer ..." [Read more]

"The manuscript followed a thorough submission and guideline process and the submission platform was very easy to follow. The peer review process was prompt and thorough as well. The correction stage was well done. The copy editing stage had a good turn around time , nevertheless the production stage took so long. Overall, i love that the entire process is transparent and trackable at every stage. " [Collapse]

Adeniyi MJ, Awosika A. Cortical arousal and autonomic regulation: The role of cold vs tepid caffeinated beverages during prolonged orthostasis. World J Methodol 2026; 16(2): 115219

21222 items Read more >>

Article Quality Tracking-Peer-Review

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied." [Collapse]

Raveglia F, Degiovanni S, Bertolaccini L, Cara A, Cassina EM, Danuzzo F, Libretti L, Pirondini E, Sibilia MC, Spinelli F, Tuoro A, De Simone M, Chiarelli M, Cioffi U, Petrella F. Beyond survival: Pain as the main determinant of long-term quality of life after thoracic trauma surgery. World J Clin Cases 2026; 14(13): 119644

"This study addresses an important and timely clinical question, providing relevant data on the use of ustekinumab in postoperative ..." [Read more]

"This study addresses an important and timely clinical question, providing relevant data on the use of ustekinumab in postoperative recurrence of Crohn’s disease. The multicenter design enhances the external validity and applicability of the findings in real-world practice. The integrated assessment combining endoscopic, clinical, and biological outcomes represents a major strength of the study. Overall, the results support the efficacy and safety of ustekinumab, particularly in a first-line setting. However, the retrospective design introduces inherent limitations, including potential selection bias and residual confounding. The relatively short follow-up period limits the ability to draw conclusions regarding long-term efficacy and durability of response. The observed differences in response among stricturing and penetrating phenotypes are intriguing but remain hypothesis-generating and require further validation in larger prospective cohorts. Despite these limitations, the study provides valuable real-world evidence supporting early use of ustekinumab in postoperative Crohn’s disease. The manuscript is well structured, clearly written, and easy to follow, with a coherent presentation of results and clinically meaningful interpretation." [Collapse]

Ma XZ, Han XZ, Zhang WY, Tian F, Zhou XC, Zhou LY, Teng YS, Lei L, Sheng JQ, Jin P, Zhao XM, Jia Y. Effectiveness of ustekinumab in postoperative Crohn's disease management: Evidence from a Chinese multicenter cohort. World J Gastroenterol 2026; 32(16): 116781

"1 Ethics: Does the ethical approval form provided by the author meet the requirements? The Ethics Committee of the Maria ..." [Read more]

"1 Ethics: Does the ethical approval form provided by the author meet the requirements? The Ethics Committee of the Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, waived the need for ethics approval. 2 Methods: Is the experimental method effective? Can it be repeated by fellow researchers (according to adequate textual/citation content presented)? The study is moderately effective as it is retrospective clinical design how ever detailed methodology is missing. furthermore, it is judged on statistical variation not on experimental results variations 3 Results: Are the results true and authentic? Is the theory or hypothesis of universal significance validated or partially validated? The results are appropriately authentic and consistent. Sample size is lower, hence hypothesis is moderately validated. Present study demonstrate the prognosis relevance which is insufficient for application in clinical settings. 4 Figures and tables: Does the author provide perfect tables, line charts and/or graphs? Or, does the author provide figures and tables that are confusing, poorly constructed and/or not well-annotated? Figure and tables are adequately presented 5 Biostatistics: Does the author provide perfect biostatistics data? Or, does the author provide tables and line charts that have mistakes in the data? Standard statistical approach is used in the current study with respect to study design 6 References: Does the author scientifically and reasonably cite the latest references which are important in this field and related to the scientific problems and research hypotheses addressed in the study? Or, does the author self-cite, omit, mis-cite and/or over-cite references? Appropriate 7 Language: Does the language in article correctly, clearly and concisely express the information? Or, does the article have multiple grammatical and spelling mistakes? Acceptable format, formal and scientifically clear 8 Caveats or drawbacks: What are the caveats or drawbacks for the results? Single center results Lower sample size which might effect on statistical significance Transparency in methodology " [Collapse]

Stawarz K, Gorzelnik A, Klos W, Korzon J, Kissin F, Bienkowska-Pluta K, Stawarz G, Rusetska N, Zwoliński J. Prognostic value of clinicopathological parameters in adenoid cystic carcinoma: A retrospective cohort study. World J Clin Oncol 2026; 17(4): 116329

"This review article explores the complex relationship between nutrition, ultra‑processed food consumption, and colorectal cancer ..." [Read more]

"This review article explores the complex relationship between nutrition, ultra‑processed food consumption, and colorectal cancer development. It highlights how diets rich in additives, refined sugars, and industrial fats contribute to dysbiosis, inflammation, and oxidative stress, thereby increasing cancer risk. Conversely, dietary interventions such as fasting, caloric restriction, and ketogenic regimens show promise in reprogramming tumor metabolism and enhancing therapeutic responses. The authors emphasize that while mechanistic evidence is strong, clinical studies remain limited, heterogeneous, and often small in scale. Overall, the paper underscores the potential of personalized nutrition as a complementary strategy in colorectal cancer prevention and treatment, but stresses the need for well‑designed trials to validate safety, adherence, and long‑term outcomes." [Collapse]

Lima RSP, Sousa JDS, Neres MSO, de Sousa DJM, Martins JA, Pereira IC, da Silva ACA, Severo JS, Torres-Leal FL, da Silva MTB. Colorectal cancer therapy and nutrition: From ultra-processed consumption to metabolic reprogramming. World J Gastrointest Oncol 2026; 18(4): 115511

"This article provides valuable insight into the role of CD161⁺CD8⁺ T cells in HBV‑associated hepatocellular carcinoma, emphasizing ..." [Read more]

"This article provides valuable insight into the role of CD161⁺CD8⁺ T cells in HBV‑associated hepatocellular carcinoma, emphasizing their contribution to T‑cell exhaustion. The study highlights that PD‑1 inhibitors reduce PD‑1⁺ subsets but fail to affect CD161 expression, suggesting independent regulatory mechanisms. These findings underscore CD161 as a distinct and promising immunotherapeutic target, complementing but not overlapping with PD‑1 blockade strategies. While the evidence is compelling, broader patient cohorts and longitudinal studies will be essential to confirm clinical relevance and therapeutic potential." [Collapse]

Liu CR, Zhang M, Wang MQ, Zhang W, Li J, Shi GZ, Liang FF, Li YP, Huang N. CD161⁺CD8⁺ T cells in patients with hepatitis B virus-associated hepatocellular carcinoma. World J Gastrointest Oncol 2026; 18(4): 114547

"The study presents a novel synthetic lethality strategy combining atorvastatin and gefitinib for colorectal cancer. It demonstrates ..." [Read more]

"The study presents a novel synthetic lethality strategy combining atorvastatin and gefitinib for colorectal cancer. It demonstrates strong experimental evidence with both in vitro and in vivo validation, highlighting mechanistic clarity via the AMPK‑SREBP1 pathway. While promising and translational, limitations in sample size and treatment duration suggest further clinical validation is needed." [Collapse]

Huang JH, Ma JQ. HMGCR loss is synthetic lethal with PIK3CD inhibition in colorectal cancer cells. World J Gastrointest Oncol 2026; 18(4): 114220

"The work is very interesting. In particular, the discussion is rich and leads to many insights into the relationship between diabetes ..." [Read more]

"The work is very interesting. In particular, the discussion is rich and leads to many insights into the relationship between diabetes and coronary heart disease (CAD) and how to address both simultaneously in a prevention strategy. This paper could be a trailblazer for further research investigating the use of other drugs currently used to treat both diabetes and CAD." [Collapse]

Tsironikos GΙ, Zakynthinos GΕ, Kyprianidou D, Rammou V, Antonogiannis T, Bargiota A, Zakynthinos E, Tsolaki V. Metformin fails to prevent diabetes in non-diabetic cardiovascular patients: Systematic review and meta-analysis. World J Cardiol 2026; 18(4): 115712

"The authors deserve praise for coming up with a new and well-thought-out way to solve a difficult clinical problem. This case report ..." [Read more]

"The authors deserve praise for coming up with a new and well-thought-out way to solve a difficult clinical problem. This case report beautifully shows how customised three-dimensional printed titanium ribs can be used successfully with bilateral flap coverage to fix a complicated chest wall defect. Combining cutting-edge 3D printing technology with sound reconstructive surgical principles is a forward-thinking approach that works well and looks good. The manuscript is well-organised, clearly written, and backed up by relevant clinical information and images. It gives thoracic and reconstructive surgeons a lot of useful information about planning before surgery, customising implants, and surgical techniques. This report adds important information to the growing field of personalised surgical reconstruction and sets a good example for how it can be used in the future." [Collapse]

Li XA, Chen JY, Bu J, Wu HW. Customized three-dimensional printed titanium ribs combined with bilateral flaps for reconstruction of chest wall defect: A case report. World J Orthop 2026; 17(4): 117533

"The manuscript "Management and Prevention of Iatrogenic Ipsilateral Femoral Neck Fracture During Intramedullary Nailing of Femoral ..." [Read more]

"The manuscript "Management and Prevention of Iatrogenic Ipsilateral Femoral Neck Fracture During Intramedullary Nailing of Femoral Shaft" talks about a clinically important but often overlooked problem in orthopaedic trauma surgery. The authors did a great job of stressing how important it is to be careful during intramedullary nailing. They also talked about both ways to avoid problems and how to handle them when they do happen. The article is well-organised, with a clear progression from identifying the problem to finding solutions that work. The focus on early diagnosis, safety measures during surgery, and imaging protocols adds a lot of clinical value. The section on technical details and surgical tips is especially interesting, making the paper very useful for both new and experienced surgeons. The manuscript adds to the existing body of literature by putting together current evidence and making recommendations that can help lower complication rates and improve patient outcomes. In general, this article is well-written, informative, and useful in a clinical setting, so it should be published." [Collapse]

Nallakumarasamy A, Vetrivel VN, Balaji VP, Yadav R, Jeyaraman N, Muthu S, Jeyaraman M. Management and prevention of iatrogenic ipsilateral femoral neck fracture during intramedullary nailing of femoral shaft. World J Orthop 2026; 17(4): 116107

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

Usuda D, Furukawa D, Imaizumi R, Ono R, Kaneoka Y, Nakajima E, Kato M, Sugawara Y, Shimizu R, Inami T, Sakurai R, Kawai K, Matsubara S, Tanaka R, Suzuki M, Shimozawa S, Hotchi Y, Osugi I, Katou R, Ito S, Mishima K, Kondo A, Mizuno K, Takami H, Komatsu T, Nomura T, Sugita M. Perforative peritonitis caused by long-term retention of a rectal foreign body: A case report. World J Clin Cases 2026; 14(11): 119572

"Congratulations on the publication of your paper. This is a significant achievement, and I am delighted to see that your dedicated ..." [Read more]

"Congratulations on the publication of your paper. This is a significant achievement, and I am delighted to see that your dedicated efforts in daily clinical practice and academic work have borne fruit. I read your paper with great interest, particularly because my own specialty is emergency medicine. I also occasionally encounter cases of anorectal foreign bodies in clinical practice, and I believe your paper will serve as a highly valuable reference for the management of such cases in the future. The manuscript is very well organized, clear, and easy to follow. In addition, it incorporates up-to-date information and presents the topic in a balanced and informative manner. Overall, I consider this to be a high-quality paper of substantial clinical value. In recognition of these strengths, I would give this work the highest evaluation. Writing and publishing a paper while maintaining a busy clinical workload is no small accomplishment, and I sincerely hope that you will continue to build on this success and further expand your academic achievements. Congratulations once again on this excellent work." [Collapse]

"5-FU is the basis of the therapeutic regimens for the pharmacological treatment of gastric cancer (GC). However, the main downside ..." [Read more]

"5-FU is the basis of the therapeutic regimens for the pharmacological treatment of gastric cancer (GC). However, the main downside of this treatment is the development of resistance, which, understandably, negatively affects patients’ clinical outcomes. Therefore, innovative therapeutic strategies are needed to overcome 5-FU resistance and improve the prognosis of GC. The authors of the study under review investigated the effects of Xiangshaliujunzi decoction (XSLJZD) on GC cell lines. They found that XSLJZD inhibited cell viability and proliferation, while promoting PANoptosis in 5-FU-resistant cells. Suppression of ZEB1 increased pyroptosis, apoptosis, and the expression of other proteins associated with programmed cell death. The selection of this work for comment was based on two reasons: i) the use of complementary therapy, whether or not based on traditional Chinese Medicine in the treatment of various benign and malignant digestive disorders, should be adopted internationally. The results are no longer empirical but are based on valid clinical and laboratory data, ii) The authors, in designing their study, among other things, investigated the effect of PANoptosis processes (apoptosis, pyroptosis, and necroptosis) which are a very hot topic of research internationally not only in malignant digestive diseases, but also in a host of other benign conditions such as inflammatory bowel disease. Their results, although experimental, reinforce the view that XSLJZD overcomes 5-fluorouracil (5-FU) resistance in GC by inducing PANoptosis." [Collapse]

Gao H, Yin DF, Xing XR, Zhou LJ, Yu R. MiR-200a-3p/ZEB1/IRF1-mediated PANoptosis prompts Xiangshaliujunzi decoction to overcome 5-fluorouracil resistance in gastric cancer. World J Gastroenterol 2026; 32(14): 114331

"This draft provides a clear and engaging overview of diabetic retinopathy (DR), presenting it as more than just a vascular complication ..." [Read more]

"This draft provides a clear and engaging overview of diabetic retinopathy (DR), presenting it as more than just a vascular complication and highlighting its neurovascular nature. Diabetic retinopathy (DR), and its effective explanation as a complex, multifactorial, and increasingly recognized neurovascular disorder rather than solely a microvascular complication. The paper effectively emphasizes the global burden of the disease and the limitations of current treatments, especially anti-VEGF therapies, while drawing attention to the importance of early retinal changes. One of the main strengths of the review is its broader perspective beyond glucose control. The discussion of inflammation, lipid metabolism, and immune processes is well integrated and reflects current thinking in the field. The discussion of broader perspective as “beyond-glycemia” framework, reinforcing the need for multidimensional therapeutic strategies. The writing flows logically, making complex mechanisms easier to follow. The section on the gut-retina axis is particularly interesting and adds a fresh dimension to the topic. It clearly explains how gut microbiota may influence retinal health through metabolic and immune pathways. The inclusion of microbial metabolites, extracellular vesicles, and immune modulation as mediators of gut-retina communication demonstrates a developed understanding of the current evidence. Overall, the draft is well-organized, informative, and forward-looking, with a strong focus on potential new therapies and future research directions. " [Collapse]

Zeppieri M, Drigo A, Capobianco M, Visalli F, Cappellani F, Musa M, Giglio R, Tognetto D, Khouyyi M, Gagliano C, D’Esposito F, Inferrera L. Beyond glycemia: The influence of systemic inflammation, lipids, and the gut-retina axis in diabetic retinopathy. World J Diabetes 2026; 17(3): 114603

"It has been stated that PPI s alone are good effective for aspirin induced gastrointestinal bleeding, but not sufficiently effective ..." [Read more]

"It has been stated that PPI s alone are good effective for aspirin induced gastrointestinal bleeding, but not sufficiently effective for clopidogrel induced gastrointestinal bleeding. However,co-administration with rebamipide provides sufficient hemostatic effect. Please comment the reason why pPI with rebamipide is good effect for the gastrointestinal bleeding with clopidogrel. Please comment the side effect of long term with pPI use." [Collapse]

Kim M, Chi SA, Kim JE, Kim ER, Hong SN, Kim YH, Kim K, Chang DK. Optimal strategies for mitigating gastrointestinal bleeding in patients receiving antiplatelet therapy: Real-world study. World J Gastroenterol 2026; 32(14): 115790

"The article explains very well the relevance of the Boruta variables in the clinical-endoscopic model for AIG-associated G-NETs and ..." [Read more]

"The article explains very well the relevance of the Boruta variables in the clinical-endoscopic model for AIG-associated G-NETs and clearly highlights its strengths and limitations. The text structure is good, and the logical presentation of information facilitates the understanding of the process and the mechanisms involved. In addition, the text is grammatically correct, managing to present new perspectives on how feature selection and the integration of clinical and endoscopic biomarkers can contribute to risk stratification and personalized management of patients with AIG. This approach makes a clear contribution to the specialized literature, opening avenues for future research and practical application of predictive models. " [Collapse]

Yu QQ. Risk stratification of gastric neuroendocrine tumors in autoimmune gastritis: Evaluating the clinical value of an integrated clinical-endoscopic model. World J Gastroenterol 2026; 32(13): 115440

"This is a well-written and presented a rare case report on Splenic tuberculous mass following anti-tuberculosis therapy was ..." [Read more]

"This is a well-written and presented a rare case report on Splenic tuberculous mass following anti-tuberculosis therapy was misdiagnosed as a splenic tumor. Careful questioning of a patient's medical history is crucial for avoiding misdiagnosis and inappropriate treatment. In this case, the failure to carefully question the patient's medical history at the outset is a deficiency. I think that this manuscript is suitable and worth to be published in World Journal of Gastrointestinal Surgery. " [Collapse]

Li ZK, Zhang K, Zhang HL, Lv XL, Guo JQ, Tan W. Splenic tuberculous mass following anti-tuberculosis therapy was misdiagnosed as a splenic tumor: A case report. World J Gastrointest Surg 2026; 18(3): 115137

" The article meets basic ethical standards with reported approval, though fuller disclosure of consent procedures would enhance ..." [Read more]

" The article meets basic ethical standards with reported approval, though fuller disclosure of consent procedures would enhance transparency. The methodology is appropriate and largely reproducible, but lacks some detail on controls and implementation, limiting full replication. Results are logically presented and consistent with the study design, providing partial support for the hypothesis, though broader generalizability is constrained. Figures and tables are relevant but occasionally insufficiently annotated, reducing clarity. Biostatistical analysis is acceptable, yet could be strengthened through more comprehensive reporting of effect sizes and confidence intervals. References are generally current and relevant, although inclusion of additional recent key studies would improve scholarly depth. The language is clear and mostly concise, with minor grammatical issues. Key limitations include a relatively small and possibly non-representative sample, potential bias, and inadequate discussion of confounding factors, all of which may affect the strength and applicability of the conclusions. " [Collapse]

Chen X, Zhang LL, Zhou Y, Dong DX, Qian XY. Mitochondrial autophagy in diabetes-related cognitive decline and skin ulcers: Mechanistic insights and therapeutic implications. World J Diabetes 2026; 17(3): 112177

"This is a single-center, double-blind, randomized, placebo-controlled trial that enrolled a sufficient number of patients who met ..." [Read more]

"This is a single-center, double-blind, randomized, placebo-controlled trial that enrolled a sufficient number of patients who met the Rome IV diagnostic criteria for FD. Patients were randomized to receive LPZ (30 mg once daily) in combination with FM (flupenthixol 0.5 mg + melitracen 10 mg) or a matching placebo for 2 weeks, followed by a 4-week follow-up. At week 2, the clinical response rate was higher in the LPZ + FM group than in the placebo group. The LPZ + FM group showed greater reductions in PDS, SF-NDI, PHQ-9, Generalized Anxiety Disorders-7, and Pittsburgh Sleep Quality Index scores, with improvements maintained throughout the follow-up. The first comment concerns the usefulness of such studies. These studies are very useful in daily clinical practice precisely because of the magnitude of the problem worldwide. The second comment concerns the study design. In my opinion, another pure group could be included that would receive only the FM combination. The results could separate the percentage contribution of each regimen to the final clinical outcome. In any case, as the authors note, multicenter studies are required to demonstrate the effectiveness of a combination of pharmaceutical agents for the treatment of this frequent and condition with significant functional consequences." [Collapse]

Wang XY, Yin KH, Cheng L, Wang XY, Qiao Y, Tang XR, Wang B, Yan XJ, Chen SL. Efficacy and safety of lansoprazole combined with flupentixol-melitracen for functional dyspepsia: A randomized, double-blinded, placebo-controlled clinical trial. World J Gastroenterol 2026; 32(13): 117115

"This is a compelling topic with significant clinical relevance. The development of this system stems from a key gap: while ..." [Read more]

"This is a compelling topic with significant clinical relevance. The development of this system stems from a key gap: while guidelines for several incidental findings already exist, consistent and integrated recommendations within radiology reports are lacking. The objectives of this proposal were clearly presented and well defined. The aims were to standardize terminology and decision-making for incidental findings while ensuring a transparent and reproducible link between the findings and their corresponding recommendations. Furthermore, the Incidental-Reporting and Data System (I-RADS) seeks to facilitate data collection and establish an infrastructure for artificial intelligence algorithms to learn from clearly labeled, standardized datasets—enabling machine learning, registries, and big-data research in ways that current fragmented guidelines cannot. Additionally, I-RADS can be integrated into structured reporting platforms, thereby streamlining the diagnostic workflow. I-RADS is not intended to replace existing guidance on incidental findings, such as the ACR recommendations, but rather to complement and consolidate them into a single, simplified cross-sectional system. The proposed I-RADS system features a conceptual framework designed to provide a unified and simplified approach to the classification and communication of incidental findings across imaging modalities and anatomical regions. The reviewer acknowledged that the proposal for the Incidental-Reporting and Data System represents an innovative effort with positive implications. However, unlike other systems, I-RADS must account for a wide range of miscellaneous conditions—such as aortic dissection, occult or chronic splenic rupture, thrombus in the left atrium or main pulmonary artery, retained foreign bodies, and displacement of iatrogenic grafts—which, while not malignant, are life-threatening or hazardous. These should be carefully considered. The methodology for the development of I-RADS requires revision, and the efficacy of the system needs to be validated." [Collapse]

Arkoudis NA, Moschovaki-Zeiger O, Koutserimpas C, Lama N, Velonakis G, Filippiadis D, Spiliopoulos S, Kelekis N. Proposing Incidental-Reporting and Data System: A classification system for incidental findings in radiology. World J Radiol 2026; 18(3): 119025

"TIPS is good procedure for esophageal varix. This procedure is portal vein -hepatic vein shunt. TIPS decrease portal pressure and ..." [Read more]

"TIPS is good procedure for esophageal varix. This procedure is portal vein -hepatic vein shunt. TIPS decrease portal pressure and causes highout for heart. Some patient after TIPS suffer from Eck and heart failure. Please comment about the diameter of TIPS and preoperative heart. What kinds of parameter for heart is suitable parameter for heart failure after TIPs? " [Collapse]

Zhang TQ, Zhang L, Yong X, Tian C, Chen BJ, Qin JP, Mu D, Tang SH. Transjugular intrahepatic portosystemic shunt for variceal bleeding due to hereditary hemorrhagic telangiectasia with cirrhosis: A case report. World J Gastroenterol 2026; 32(12): 119002

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Peer-Reviewers and Manuscript Statistics

Editorial board members: 2263

Peer-reviewers: 37120

Manuscripts received today: 1

Manuscript reviews today: 6

Unhandled manuscripts today: 175

Active peer-reviewers today: 250

Reviewer acceptance today: 6

Reviewer refusals today: 6

Total accepted manuscripts: 41219

Total rejected manuscripts: 45384

Total peer-reviewers: 4794435

Total submissions: 38915