Baishideng Publishing Group

Sacasa F, Ploneda C, Cervantes M, Betancourt B, Casal J, Bedoya J, Valladares W. Superior mesenteric artery syndrome and right paraduodenal hernia causing intestinal obstruction during pregnancy: A case report. World J Gastrointest Surg 2026; 18(5): 117565

"As a frequent researcher and a reviewer for WJP, I would like to humbly offer a smart suggestion to further improve the efficiency ..." [Read more]

"As a frequent researcher and a reviewer for WJP, I would like to humbly offer a smart suggestion to further improve the efficiency of the Baishideng Publishing Group (BPG): Suggestion: Consider developing a more intuitive "Interactive File Exchange Module" within the F6 Publishing System. Proposed Features: Dedicated Drop-zone: A specific area within the "Author Comments" or "Production Query" section where authors can drag and drop large image files (TIFF/PNG) or tables directly, bypassing email size limits. Version Control: A simple interface to manage different versions of figures (e.g., "Figure 2D_v2") to avoid confusion between the production team and the authors. Real-time Status Tags: Indicators showing whether the editor has successfully downloaded the file or if the file is pending review. Benefit: This enhancement would significantly reduce the back-and-forth emails regarding missing files and ensure that high-resolution figures and supplementary data are archived securely and efficiently. I truly appreciate your consideration of this suggestion. Thank you for fostering such a supportive environment for scholars. " [Collapse]

Gu JX, Liu CQ, Chen GX, Yao T, Sun ZX, Wang Y. Post-stroke depression update 2025: Mechanisms, prediction, and management. World J Psychiatry 2026; 16(6): 115996

"We are very pleased with the professional and efficient way our manuscript was handled. The peer review process was fair and ..." [Read more]

"We are very pleased with the professional and efficient way our manuscript was handled. The peer review process was fair and constructive, and all of the production materials—including the PDF layout, online full-text, figures, and tables—are of excellent quality. The entire publication process went smoothly, and the editorial team was responsive and supportive throughout. Many thanks to the editorial office and all the reviewers for their hard work and valuable feedback. " [Collapse]

Wei YG, Yang LH, Qin SS, Chen YL, Yan JN, Liu RX, Ma YM, Wang C, Song ZJ, Wang F, Ji GJ. Mental stress recognition using interpretable machine learning models with heart rate variability among Chinese university students. World J Psychiatry 2026; 16(6): 116013

"I had a really good experience with this journal. The submission system was easy to use, the review process was fair and constructive, ..." [Read more]

"I had a really good experience with this journal. The submission system was easy to use, the review process was fair and constructive, and publication didn't drag on at all. The online display of figures, tables, and text was excellent; everything looked clean and clear. Very satisfied overall. I would happily submit here again and would recommend it to others. " [Collapse]

Ji W, Wang YQ, Zhao YY, Zhang WC, Jiang W. Alleviating social anxiety in college students: A comprehensive positive emotion, engagement, relationships, meaning, and accomplishment model-based group counseling approach. World J Psychiatry 2026; 16(6): 118944

"We are happy with the submission. I hope that y the editor can provide us with additional invited papers. We look forward to working ..." [Read more]

"We are happy with the submission. I hope that y the editor can provide us with additional invited papers. We look forward to working with BPG. The reviewing process needs work. It takes numerous months before reviewers are found. The system could be improved by slimlining the entire submission process. Other journals take 1-2 for complete publication. " [Collapse]

Capobianco M, Cappellani F, Khouyyi M, Nicolosi SG, D’Esposito F, Musa M, Battista M, Barboni P, Gagliano C, Zeppieri M. Beyond vision: The overlooked burden of depression in glaucoma patients. World J Psychiatry 2026; 16(6): 116408

"I am delighted to have my paper published in this journal. The entire process from submission, peer review, revision to final ..." [Read more]

"I am delighted to have my paper published in this journal. The entire process from submission, peer review, revision to final publication was well-organized, transparent and efficient. The editors were patient and helpful throughout all stages. The reviewers offered insightful and rigorous suggestions, which effectively polished the content and strengthened my research. I sincerely appreciate all the efforts from the editorial office and reviewers. It has been a wonderful publishing experience. " [Collapse]

Yu LJ, Ye LJ, Wang Y, Xu CY, Ye D, Huang M. Effect of integrating personalized psychological nursing with humanistic care on treatment outcomes in patients with advanced cancers. World J Psychiatry 2026; 16(6): 115202

"Publishing our work in [Journal Name] has been a truly rewarding experience. We were deeply impressed by the journal’s rigorous yet ..." [Read more]

"Publishing our work in [Journal Name] has been a truly rewarding experience. We were deeply impressed by the journal’s rigorous yet constructive peer review process, which significantly sharpened the clarity and depth of our manuscript. The editorial office was highly professional and efficient, ensuring a smooth handling from submission to final acceptance. We firmly believe that the high reputation and broad readership of [Journal Name] will provide an excellent platform to disseminate our findings. It is our sincere honor to contribute to this esteemed journal, and we hope our work sparks further dialogue within the community. " [Collapse]

Wang FZ, Xu JS, Sun H, Wang XL, Huang Y. Association between illness perception and depression in colorectal cancer patients: Chain mediating effects of self-efficacy and post-traumatic growth. World J Psychiatry 2026; 16(6): 119401

"Thanks to all the reviewers, editors and publication team for publishing my manuscript in your renowned journal. It was a wonderful ..." [Read more]

"Thanks to all the reviewers, editors and publication team for publishing my manuscript in your renowned journal. It was a wonderful experience working with such a dedicated professionals. Your suggestions brought a positive change in my manuscript. The whole review process was so transparent and fast. I was also informed timely about each step of the process. " [Collapse]

Sangwan R, Agrawal H, Agarwal N, Ather H, Kumar P, Gupta N. Predictors of clinically significant complications after stoma reversal: A prospective analytical study. World J Gastrointest Pharmacol Ther 2026; 17(2): 120325

"Thanks to all the reviewers, editors and publication team for publishing my manuscript in your renowned journal. It was a wonderful ..." [Read more]

Balhara K, Sikaria A, Saini D, Agrawal H, Gupta N, Agarwal N, Mardi A. Low-cost dynamic fascial traction using serial Bogota bag tightening in open abdomen management: A prospective randomized study. World J Gastrointest Pharmacol Ther 2026; 17(2): 118848

"Publishing in the World Journal of Gastrointestinal Surgery has been a highly rewarding experience. We deeply appreciate the insightful ..." [Read more]

"Publishing in the World Journal of Gastrointestinal Surgery has been a highly rewarding experience. We deeply appreciate the insightful and constructive comments from the peer reviewers, which greatly strengthened our study. The assistant editor, language editor, and production team were exceptionally professional and meticulous in their work. We highly recommend this journal to fellow researchers in the field of gastrointestinal surgery " [Collapse]

Zhou RQ, Yang PJ, Liu LG, Zhang JB, Ye ZD, Tan HD. Spleen stiffness accurately tracks early and sustained portal pressure changes after transjugular intrahepatic portosystemic shunt. World J Gastrointest Surg 2026; 18(5): 118030

"Throughout the submission and publication process, I had very friendly communication with the journal's editors. Every email was ..." [Read more]

"Throughout the submission and publication process, I had very friendly communication with the journal's editors. Every email was promptly replied to, and both the peer review and feedback were handled quickly. Additionally, due to my hospital's reimbursement policy requiring direct bank transfer to the journal's headquarters, you helped me resolve this issue smoothly, enabling me to complete the payment and subsequent procedures successfully. The entire submission process went seamlessly—it was a truly pleasant experience. Thank you. " [Collapse]

Tou LZ, Wu D, Jiang C, Zheng JJ, Sun Z, Li JH, Que HF, Luo DS, Xu HT, Beisani M. Safety and efficacy of indocyanine green tracer-guided robotic segmental gastrectomy in early gastric cancer: A case report. World J Gastrointest Surg 2026; 18(5): 117647

"The editorial process was efficient and well-organized. The peer review was rigorous and constructive, which significantly improved ..." [Read more]

"The editorial process was efficient and well-organized. The peer review was rigorous and constructive, which significantly improved our manuscript. The production team responded promptly to queries. We appreciate the transparent workflows and the final publication quality. Overall, it is a positive experience working with World Journal of Gastrointestinal Surgery, and we would consider submitting again in the future. " [Collapse]

Yan LQ, Li P. Effect of Neiguan and Gongsun acupuncture on gastric electrical rhythm after gastric cancer surgery. World J Gastrointest Surg 2026; 18(5): 115921

"We thank editor, reviewers and other personal for their efforts in making our article great and helping us to publish this paper. ..." [Read more]

"We thank editor, reviewers and other personal for their efforts in making our article great and helping us to publish this paper. Reviewer comments made readability of the paper better and scientifically sound. The editing process was smooth and timely. Modifications in the proofreading were made appropriate and in time. " [Collapse]

Kulandaivelu A, Vaithiyam V, Mehta K, Reddy RT, Ahuja A, Sirohi N, Sonika U, Dalal A, Kumar A, Puri AS, Sachdeva S. Fructose malabsorption associated with functional abdominal bloating: Case-control study. World J Gastrointest Pharmacol Ther 2026; 17(2): 121264

"The submission and publication process was smooth and efficient. The online system is user-friendly, and the peer review is fair, ..." [Read more]

"The submission and publication process was smooth and efficient. The online system is user-friendly, and the peer review is fair, rigorous and constructive, providing valuable professional comments that significantly improved my manuscript. The editorial team communicated timely and responsively with clear guidance. I am fully satisfied with the whole experience and will submit future papers here and recommend it to colleagues. " [Collapse]

Zhang YL, Zong L, Hu HB. Endoscopic submucosal dissection for early gastric cancer: A review of comparative perspectives on treatment outcomes vs gastrectomy. World J Gastrointest Surg 2026; 18(5): 118341

"This journal delivers thoughtful and professional publishing services. All required online documents are neatly arranged, and each ..." [Read more]

"This journal delivers thoughtful and professional publishing services. All required online documents are neatly arranged, and each publishing step is easy to follow. The provided academic criteria and authenticity test reports meet high standards. Both the publication duration and editorial regulations are well regulated. The anonymous review is efficient, and the professional feedback is fair, objective and highly valuable to my work. " [Collapse]

Pan CP, Zhang CH, Wang SL, Ni XC, Wang HB, Yu JW. Clinical comparison of laparoscopic vs open distal gastrectomy for advanced gastric cancer: Perioperative safety, recovery, and survival. World J Gastrointest Surg 2026; 18(5): 117809

"I’m pleased with all arrangements for manuscript publication here. The online forms for full-text submission are practical, and the ..." [Read more]

"I’m pleased with all arrangements for manuscript publication here. The online forms for full-text submission are practical, and the entire publishing workflow runs steadily. The academic specifications and misconduct screening reports are fully reliable. The journal has a sensible publication cycle and standard editorial rules. The blind peer review is well scheduled, and the insightful comments have aided my revision greatly with unbiased judgments. " [Collapse]

Yuan Y, Xiao S. Effect of transcutaneous electrical acupoint stimulation at Zusanli and Neiguan on postoperative recovery in patients with colorectal cancer. World J Gastrointest Surg 2026; 18(5): 116996

"My experience during the publication process has been excellent. The online document templates are practical, and all publishing ..." [Read more]

"My experience during the publication process has been excellent. The online document templates are practical, and all publishing procedures operate in good order. The journal’s academic guidelines and integrity check reports are professional and dependable. It maintains a proper publication timeline and adheres to rigorous editorial criteria. The peer review period is well arranged, and the blind review system works effectively. The feedback I received offers great guidance for my paper, and all evaluations are impartial and objective. " [Collapse]

Kang NS, Fang HJ, Zheng SH. Gut-liver axis management and its surgical application: A perspective from “liver governing free flow”. World J Gastrointest Surg 2026; 18(5): 117321

"The editor's comments and review report are very helpful for our published manuscript. And my suggestions include how AI can be used ..." [Read more]

"The editor's comments and review report are very helpful for our published manuscript. And my suggestions include how AI can be used on future papers, and the requirements of the AI app should be given to the authors. In all, the peer review report of our manuscript is fair or objective. Thanks very much. " [Collapse]

Feng Y, Hu XH, Xiao B. Machine learning and radiomics for differentiating severe from moderately severe acute necrotizing pancreatitis on contrast-enhanced computed tomography. World J Gastrointest Surg 2026; 18(5): 115903

"We have reviewed the bibliographic information and the published manuscript, and we confirm that they are accurate. We are satisfied ..." [Read more]

"We have reviewed the bibliographic information and the published manuscript, and we confirm that they are accurate. We are satisfied with the credibility, transparency, and publication quality of the World Journal of Gastrointestinal Surgery. The peer-review process was fair, objective, and constructive. The reviewers’ comments helped improve the clarity and overall quality of our manuscript, and the editorial communication was timely and professional. We sincerely appreciate the efforts of the editors, reviewers, and production team. The entire publication process was well organized and professionally handled. We are pleased with the final published version of our manuscript and grateful for the opportunity to publish our work in the journal. " [Collapse]

Yoon S, Ji WB, Um JW, Hong KD. Optimizing radiofrequency ablation parameters for perianal fistula treatment: A porcine model study. World J Gastrointest Surg 2026; 18(5): 119504

"I recently had the opportunity to publish a manuscript in the World Journal of Gastrointestinal Surgery. Overall, my experience with ..." [Read more]

"I recently had the opportunity to publish a manuscript in the World Journal of Gastrointestinal Surgery. Overall, my experience with the journal was positive. The peer-review process was well organized, constructive, and professionally managed. The reviewers’ comments were useful and helped improve the clarity and quality of the final manuscript. The editorial process after acceptance was somewhat long and required careful attention to several formatting and editing details. Although this phase was a little laborious, the editorial office remained polite and responsive throughout the process. " [Collapse]

Patriti A, Graziano F, Chiari R. Mucinous rectal adenocarcinoma and neoadjuvant therapy: Implications for surgical practice. World J Gastrointest Surg 2026; 18(5): 115825

21437 items Read more >>

Article Quality Tracking-Peer-Review

"Post-stroke depression (PSD) is a frequent complication that worsens recovery and quality of life. Clinicians should prioritize early ..." [Read more]

"Post-stroke depression (PSD) is a frequent complication that worsens recovery and quality of life. Clinicians should prioritize early screening of PSD, especially in patients with cognitive impairment, severe disability, or social isolation. Biological markers such as inflammation and neurotransmitter imbalance may guide risk stratification, while predictive models can support monitoring. Management requires a multimodal approach: antidepressants, psychotherapy, and rehabilitation programs, complemented by family and social support. If integrated into routine stroke care, these strategies enable timely intervention, reduces complications, and promote fast functional recovery." [Collapse]

Gu JX, Liu CQ, Chen GX, Yao T, Sun ZX, Wang Y. Post-stroke depression update 2025: Mechanisms, prediction, and management. World J Psychiatry 2026; 16(6): 115996

"This study is methodologically rigorous, employing a large sample size, LASSO regression, and dual validation to ensure robust results. ..." [Read more]

"This study is methodologically rigorous, employing a large sample size, LASSO regression, and dual validation to ensure robust results. The dynamic online nomogram enhances clinical usability and identifies clear risk factors, including cognition, albumin, and surgical parameters. Limitations include its single‑institution scope, short validation period, and the need for prospective testing of clinical impact. Overall, it provides a solid foundation and meaningful step toward proactive management of emergence delirium in older adults." [Collapse]

Xin Y, He B, Wei XH, Yan YL, Huang C, Gao CY, Wang S, Zhang GM, Li R, Wu Y. Construction and validation of a predictive model for the risk of emergence delirium in older adult patients. World J Psychiatry 2026; 16(6): 115839

"This is a well-written and presented a rare case report on "Clinical management of porcelain gallbladder: A case report". This ..." [Read more]

"This is a well-written and presented a rare case report on "Clinical management of porcelain gallbladder: A case report". This manuscript gives additional new knowledge to the existing literature.Porcelain gallbladder is a rare clinical entity that should always be considered due to its well-established association with gallbladder carcinoma. I think that this manuscript is worth to be published in the World Journal of Gastrointestinal Surgery." [Collapse]

Chen SJ, Chen S, Hu AY, Li QS, Fan Y, Chen YG, Tian S, Li HL, Peng CJ, Han M. Clinical management of porcelain gallbladder: A case report. World J Gastrointest Surg 2026; 18(5): 116359

"This article is well structured and fully compliant with the STROBE checklist. This retrospective study systematically compared the ..." [Read more]

"This article is well structured and fully compliant with the STROBE checklist. This retrospective study systematically compared the efficacy and safety of traction-preclosure-assisted endoscopic full-thickness resection (TPC-EFTR) with conventional EFTR for the treatment of gastric subepithelial tumors (SETs). The authors clearly formulated the inclusion and exclusion criteria, with a particular emphasis on endoscopic contraindications for lesions characterized by large size, extraluminal growth, dissemination, or potential recurrence. Both primary and secondary outcome measures were well defined in detail. Regarding primary efficacy outcomes, the en bloc resection rates were comparable between the two groups, whereas the TPC-EFTR group achieved a significantly higher complete resection rate. For secondary outcomes, the TPC-EFTR group demonstrated superior safety profiles, including shortened operation time and wound closure time, as well as a reduced incidence of pneumoperitoneum. In terms of postoperative prognosis, no significant between-group difference was observed in tumor recurrence rate, while the TPC-EFTR group presented higher EQ-VAS scores. Overall, the methodological design of this study meets the standard requirements of retrospective clinical research. Nevertheless, several limitations of this study remain to be addressed. First, although no statistically significant differences were detected, potential selection bias may exist with respect to the size and anatomical location of enrolled lesions. Second, postoperative CT examinations were performed only based on clinical symptoms, which might lead to an underestimation of the actual pneumoperitoneum rate, a limitation that has also been acknowledged by the authors. Furthermore, EFTR is a technically demanding procedure that is currently restricted to high-level tertiary hospitals. Accordingly, the clinical popularization of conventional EFTR remains challenging, and further validation and prospective investigations are still required to confirm the clinical value of TPC-EFTR. In conclusion, this study is pioneering and clinically promising, and the TPC-EFTR technique exhibits favorable application prospects. Multi-center, large-sample, and long-term follow-up studies are warranted prior to the widespread clinical application of TPC-EFTR." [Collapse]

Li X, Zhang RY, Wen XD, Li XQ, Liu WH. Traction-preclosure-assisted vs conventional endoscopic full-thickness resection for gastric subepithelial tumors: Safety, efficacy in a retrospective cohort (with video). World J Gastroenterol 2026; 32(19): 112955

"This article discusses an interesting topic. This is problem solving oriented study, with benefit to clinical practice. The comparative ..." [Read more]

"This article discusses an interesting topic. This is problem solving oriented study, with benefit to clinical practice. The comparative study showed that the MV-Flow™ has ability to visualize smaller vessels with slower blood flow, which is particularly relevant, as they challenge the prevailing concept that smaller vessels in deep endometriotic nodules are poorly vascularized. The ethics meet the requirement of the Journal. Caveats or drawbacks:“There is no previous data to allow a meaningful estimation. For this reason, we do consider this study as a preliminary exploratory study” in the “Statistical analysis”section is not adequate. The study design is not sound and the results are not sound and robust. An important limitation is that there is no golden standard(contrast-enhanced ultrasound or other methods) for reference, even the pulsed wave Doppler has not been used for attempting measurement to verify the presence of microvascularity. Using conventional power Doppler as reference is not sufficient. The dimensions displayed by the two different imaging protocols are not exactly the same dimension, as in the Figure 2 A,B,C,D, and the sampling volume is larger than good. Some punctuate color regions are artifacts, leading to an unauthentic conclusion that MV-Flow™ has very high sensitivity for microcirculation. " [Collapse]

Alcazar JL, Pich Barroso DM, Sanchez O, Brunel I, Vilches JC, Orozco R. Enhanced detection of vascularization in rectal endometriosis: A comparative study of microvascular flow and power Doppler. World J Radiol 2026; 18(5): 119223

"This important review explored the relationship between hypochlorhydria, microbial dysbiosis, and gastric mucosal immune responses, ..." [Read more]

"This important review explored the relationship between hypochlorhydria, microbial dysbiosis, and gastric mucosal immune responses, and how these factors promote the transition from chronic gastritis to metaplasia and malignancy. In addition, the authors describe recent developments in multi-omics technologies that are uncovering new dimensions of host-microbe interactions in the gastric niche, thereby extending the classic Correa cascade into a more comprehensive, ecosystem-based model of gastric carcinogenesis. It seems that future perspectives on the gastric microenvironment will shift from simple descriptions of microbes to active therapeutic and diagnostic interventions, aiming to enable personalized management of patients with gastric cancer. It is also believed that advances in metabolomic analyses, microbiome modulation, utilization of specialized pro- and prebiotics, gastric microbiome transplantation, use of targeted antimicrobial drugs, modifications of the tumor microenvironment, as well as the use of ex vivo models and artificial intelligence will contribute decisively not only to the prevention and early detection of gastric cancer but also to a more effective complementary therapeutic intervention. " [Collapse]

Zheng HC, Zhou T, Sun L, Ding X. Gastric microenvironment and gastric cancer: Interplay of acid, microbiota, and inflammation. World J Gastroenterol 2026; 32(20): 117044

"This is very interesting paper about the predictor of acute hepatic failure. Author indicates that a decrease in peripheral blood ..." [Read more]

"This is very interesting paper about the predictor of acute hepatic failure. Author indicates that a decrease in peripheral blood natural killer (NK) cells and changes in their functional markers can help predict the progression and severity of liver failure, particularly in conditions like acute-on-chronic liver failure (ACLF). A sharp reduction or dysfunction in circulating NK cells in the bloodstream—often alongside an accumulation of these cells in the liver itself—indicates an overwhelming immune response and correlates with a poorer prognosis. In severe liver diseases like hepatitis-induced ACLF, peripheral NK cells become depleted and show a higher expression of apoptosis and exhaustion markers. Studies suggest that at the time of hospital admission, evaluating circulating NK cell levels alongside standard clinical markers can effectively help identify patients who may survive spontaneously versus those who will require an urgent liver transplant. Finally, our results suggest that more recruitment of NK cells to the liver is somehow responsible for the failure of the native. Explain why peripheral natural killer cells reflect the prognosis more sensitively than other parameters of acute liver failure. a significant drop in peripheral Natural Killer (NK) cell counts and a shift in their functional profile are reliable biomarkers for predicting poor clinical outcomes. Patients with severe liver failure exhibit significantly reduced proportions of NK cells in their peripheral blood compared to healthy individuals. These peripheral NK cells often show signs of exhaustion and dysfunction. Many of them undergo apoptosis (cell death) or migrate directly into the inflamed liver tissue. Researchers have found that the degree of this peripheral NK cell reduction directly correlates with disease severity (e.g., HBV-DNA levels) and can serve as a strong predictive indicator for patient survival or the need for a liver transplant. Please tell me the mechanism between the predictor of acute hepatic failure and the degree of peripheral NK cell." [Collapse]

Xu JX, Li HG, Xu X, Lu D. Letter to the Editor: Characteristics of peripheral blood lymphocyte subpopulations in acute-on-chronic liver failure: A call for further exploration. World J Gastroenterol 2026; 32(20): 116109

"This is a good paper. Human liver ischemia/reperfusion injury (IRI) is a common and major clinical problem complicating liver surgery. ..." [Read more]

"This is a good paper. Human liver ischemia/reperfusion injury (IRI) is a common and major clinical problem complicating liver surgery. The pathogenesis underlying IRI is complex, involving a series of signaling mediators and mechanisms. This study aimed to investigate the effects of Magnesium Isoglycyrrhizinate (MgIG) on the liver function after IRI in liver resection treated with or without MgIG. MgIG is a magnesium salt of glycyrrhizic acid stereoisomer, commonly derived from licorice root. The full name of MgiG is tetrahydrate magnesium 18α, 20β-hydroxy-11-oxon orolean-12-en-3β-yl-2-O-β-D-glucopyranurosyl-α-D-glucopy ranosiduronate. Glycyrrhizin is commonly used clinically as a liver protective medicine. MgIG is the fourth generation of glycyrrhizin preparations. It has better affinity with target cell receptors, and stronger anti-inflammatory and anti-oxidation effects. It has been shown to stabilize hepatocyte membrane and improve liver function. MgIG has shown the effects of lowering the liver toxicity of free fatty acid by preventing mitochondrial damage and protecting hepatocytes from ischemia and reperfusion induced injury. Function: It provides anti-inflammatory, antioxidant, and hepatocyte membrane-stabilizing effects.　 Used post-surgery, it is associated with a more rapid decrease in liver enzymes (such as ALT and AST) and better regulation of inflammatory cytokines.Ischemia-reperfusion injury: Studies have shown it can mitigate liver damage caused by blocking the hepatic blood supply during the surgical　procedure.　Previous studies showed that MgIG administration significantly ameliorated CCl4-induced biochemical alterations and lipid peroxidation in the liver of mice or rats The protective effects of MgIG might be resulted from the elimination of oxygen free radicals before the damage to macromolecular and metabolism of the cells. I ask some questions for authors.1. Please describe the extent of liver resection and the presence or absence of cirrhosis in the patient's background. 2.Please also describe parameters other than GOT used to assess the drug's effectiveness. 3.Please provide more detailed information about the effects of MGIG on reperfusion injuries. 4.During liver surgery, how many minutes of ischemia were administered using the Pringel procedure? 5.Author’s data suggests that MG has a hepatoprotective effect on the liver, but please consider comparing it with other medications. " [Collapse]

Xie ZQ, Wei JX, Zhong JY, Luo X, Zhuang HK, Ma XW, Wang QB, Tan WL, Wang BK, Chen YJ, Li CJ, Shang CZ. Effectiveness of magnesium isoglycyrrhizinate on perioperative hepatic function protection in patients undergoing hepatectomy. World J Gastroenterol 2026; 32(19): 116513

"Simpler technique but critical evaluations noted. Important for patient care. Type 2 diabetes mellitus (T2DM) and diabetic retinopathy ..." [Read more]

"Simpler technique but critical evaluations noted. Important for patient care. Type 2 diabetes mellitus (T2DM) and diabetic retinopathy (DR) are growing global health concerns, with DR remaining a major cause of vision loss. The study identifies indirect bilirubin (IBIL) as a potential biomarker that is inversely linked to DR risk in patients with T2DM. Although the findings are clinically important, limitations such as the cross-sectional design, single-center setting, and possible confounding factors reduce generalizability." [Collapse]

Zhang Z, Shan XQ, Liang FM, Zhang LX. Letter to the Editor: Indirect bilirubin: A potential predictive biomarker for diabetic retinopathy and its clinical translational potential. World J Diabetes 2026; 17(5): 115813

"This case-control study recruited 303 participants from Kunming, exploring associations between serum vitamin D, VDR FokI polymorphism ..." [Read more]

"This case-control study recruited 303 participants from Kunming, exploring associations between serum vitamin D, VDR FokI polymorphism and diabetic retinopathy (DR) in T2DM patients. It found vitamin D deficiency and VDR FokI ff genotype were independent risk factors for DR. The study adopted rigorous grouping and standard laboratory detection, applied Sanger sequencing for accurate genotyping, and controlled common clinical confounding factors, offering valuable population evidence for DR early risk prediction. However, single-center cross-sectional design cannot confirm causality. It lacked DR severity stratification and ignored lifestyle and sunlight exposure confounders. Future work should adopt multicenter prospective cohorts and further explore the molecular mechanism of VDR variants affecting DR pathogenesis. " [Collapse]

Liu ZH, Ran ZQ, Yang R, Chen LX, Wang ZZ, Li YY, Han R. Vitamin D, vitamin D receptor FokI polymorphism, and diabetic retinopathy: A case-control study in Kunming, China. World J Diabetes 2026; 17(5): 118141

"In this manuscript, the authors aimed to establish a prognostic indicator for patients with advanced-stage hepatocellular carcinoma ..." [Read more]

"In this manuscript, the authors aimed to establish a prognostic indicator for patients with advanced-stage hepatocellular carcinoma who received nivolumab as the initial treatment. Several biochemical parameters, including alpha-fetoprotein and the neutrophil-to-lymphocyte ratio (NLR), were retrospectively analyzed. The cut-off value for NLR was determined using a receiver operating characteristic (ROC) curve to distinguish patients with survival times longer than the median survival time. However, the efficacy of this cut-off value was subsequently validated using the same cohort in which the cut-off value had originally been established. Under these conditions, it is expected that the validation would yield favorable predictive results. Therefore, because both the establishment and validation of the cut-off value were conducted within the same cohort, the significance and predictive performance of the cut-off value cannot be considered methodologically validated." [Collapse]

Guo R, Gao M. Predictive value of neutrophil-lymphocyte ratio for prognosis in patients with advanced hepatocellular carcinoma treated with programmed cell death 1 inhibitors. World J Gastroenterol 2026; 32(18): 118416

"This is a well-written and presented rare case report on "Giant serosal cavernous hemangioma of the ileum". This manuscript gives ..." [Read more]

"This is a well-written and presented rare case report on "Giant serosal cavernous hemangioma of the ileum". This manuscript gives additional new knowledge to the existing literature.The authors emphasize the importance of a better understanding of "cavernous hemangioma" by clinicians, and the necessity of timely diagnosis and treatment. I think that this manuscript is suitable ,and worth to be published in World Journal o Gastrointestinal Surgery." [Collapse]

Si HB, Qin HJ, Wang YP, Nie FF. Giant serosal cavernous hemangioma of the ileum: A case report and review of literature. World J Gastrointest Surg 2026; 18(4): 115954

"Formerly ,the neutrophil/lymphocyte ( N/R) ratio also reflected the severity of COVID-19. In this study, the authors state that the ..." [Read more]

"Formerly ,the neutrophil/lymphocyte ( N/R) ratio also reflected the severity of COVID-19. In this study, the authors state that the N/L ratio is an indicator that correlates with the prognosis of HCC receiving program inhibitor administration. NLR values have also been shown to predict survival in various cancers including urologic cancer , nasopharyngeal cancer , colon cancer , as well as lung cancer . In addition, other authors say that the NLR has been found to be a prognostic risk factor for HCC after treatments other than TACE, such as hepatectomy , liver transplantation and sorafenib therapy . Please explain the mechanism by which the N/L ratio serves as an indicator of prognosis. Explain the mechanism by which the NLR cutoff was set to 3.165. Systemic inflammatory responses have been shown to reflect the promotion of angiogenesis, and DNA damage and tumor invasion through upregulation of cytokines. A simple index of systemic inflammation is the neutrophil–lymphocyte ratio (NLR). Elevated NLR has recently been shown associated with poorer prognosis in patients with various types of malignant tumors, including colorectal cancer, HCC, intrahepatic cholangiocellular carcinoma, and pancreatic cancer. Furthermore, elevated NLR have shown a significant correlation with poor outcome in patients undergoing LT for HCC. I think that One mechanism by which elevated NLR can lead to a higher tumor recurrence rate involves an increased number of circulating neutrophils secreting the vascular endothelial growth factor (VEGF), resulting in higher levels of VEGF in the tumors. Moreover,an elevated Platelet-to-Lymphocyte Ratio (PLR), often with a cut-off , is a significant, low-cost prognostic biomarker for poor overall survival (OS) and disease-free survival (DFS) in hepatocellular carcinoma (HCC) patients. It reflects heightened systemic inflammation and correlates with tumor aggressiveness, such as large tumor size, vascular invasion, and recurrence. Please comment about platelet /lymphocyte ratio about the prognosis HCC receiving receiving program inhibitor administration. " [Collapse]

"This article addresses a clinically important issue in complex hepatocellular carcinoma surgery: the potential navigation value of ..." [Read more]

"This article addresses a clinically important issue in complex hepatocellular carcinoma surgery: the potential navigation value of combining intraoperative ultrasound with indocyanine green fluorescence imaging. The study is valuable because it evaluates not only tumor visualization but also clinically relevant endpoints, including tumor localization, occult lesion detection, margin control, perioperative outcomes, and survival-related outcomes. The topic is timely and relevant to hepatobiliary surgeons, particularly in the context of precision hepatectomy and minimally invasive liver surgery. However, the interpretation should remain cautious because the study is retrospective and single-center in design. Potential selection bias, learning-curve effects, and heterogeneity in fluorescence protocols may influence the results. The comparison also appears to reflect a systematic combined-navigation strategy versus conventional surgery rather than a pure navigation versus non-navigation comparison. Therefore, the findings are clinically encouraging and suitable for hypothesis generation, but prospective multicenter validation with standardized navigation endpoints is needed. " [Collapse]

Zhang S, Li SY, Zhou B. Navigation value of intraoperative ultrasound combined with indocyanine green fluorescence in complex hepatocellular carcinoma resection. World J Gastrointest Surg 2026; 18(4): 116412

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied." [Collapse]

Pavlidis L, Geropoulos G, Kechagias KS, Psarras K, Patel V, Reza L, Prakash N, Athanasiou C, Geropoulos V, Anestiadou E, Triantafyllou T, Sapalidis K, Laskou S, Dimitroulis D. Near-infrared fluorescence with indocyanine green for minimally invasive hernia surgery: A systematic review and evidence synthesis. World J Clin Cases 2026; 14(14): 118964

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

Walędziak M, Różańska-Walędziak A. Three-port robotic sleeve gastrectomy-another step forward: A case report. World J Clin Cases 2026; 14(14): 117795

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

Raveglia F, Degiovanni S, Bertolaccini L, Cara A, Cassina EM, Danuzzo F, Libretti L, Pirondini E, Sibilia MC, Spinelli F, Tuoro A, De Simone M, Chiarelli M, Cioffi U, Petrella F. Beyond survival: Pain as the main determinant of long-term quality of life after thoracic trauma surgery. World J Clin Cases 2026; 14(13): 119644

"This study addresses an important and timely clinical question, providing relevant data on the use of ustekinumab in postoperative ..." [Read more]

"This study addresses an important and timely clinical question, providing relevant data on the use of ustekinumab in postoperative recurrence of Crohn’s disease. The multicenter design enhances the external validity and applicability of the findings in real-world practice. The integrated assessment combining endoscopic, clinical, and biological outcomes represents a major strength of the study. Overall, the results support the efficacy and safety of ustekinumab, particularly in a first-line setting. However, the retrospective design introduces inherent limitations, including potential selection bias and residual confounding. The relatively short follow-up period limits the ability to draw conclusions regarding long-term efficacy and durability of response. The observed differences in response among stricturing and penetrating phenotypes are intriguing but remain hypothesis-generating and require further validation in larger prospective cohorts. Despite these limitations, the study provides valuable real-world evidence supporting early use of ustekinumab in postoperative Crohn’s disease. The manuscript is well structured, clearly written, and easy to follow, with a coherent presentation of results and clinically meaningful interpretation." [Collapse]

Ma XZ, Han XZ, Zhang WY, Tian F, Zhou XC, Zhou LY, Teng YS, Lei L, Sheng JQ, Jin P, Zhao XM, Jia Y. Effectiveness of ustekinumab in postoperative Crohn's disease management: Evidence from a Chinese multicenter cohort. World J Gastroenterol 2026; 32(16): 116781

"1 Ethics: Does the ethical approval form provided by the author meet the requirements? The Ethics Committee of the Maria ..." [Read more]

"1 Ethics: Does the ethical approval form provided by the author meet the requirements? The Ethics Committee of the Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, waived the need for ethics approval. 2 Methods: Is the experimental method effective? Can it be repeated by fellow researchers (according to adequate textual/citation content presented)? The study is moderately effective as it is retrospective clinical design how ever detailed methodology is missing. furthermore, it is judged on statistical variation not on experimental results variations 3 Results: Are the results true and authentic? Is the theory or hypothesis of universal significance validated or partially validated? The results are appropriately authentic and consistent. Sample size is lower, hence hypothesis is moderately validated. Present study demonstrate the prognosis relevance which is insufficient for application in clinical settings. 4 Figures and tables: Does the author provide perfect tables, line charts and/or graphs? Or, does the author provide figures and tables that are confusing, poorly constructed and/or not well-annotated? Figure and tables are adequately presented 5 Biostatistics: Does the author provide perfect biostatistics data? Or, does the author provide tables and line charts that have mistakes in the data? Standard statistical approach is used in the current study with respect to study design 6 References: Does the author scientifically and reasonably cite the latest references which are important in this field and related to the scientific problems and research hypotheses addressed in the study? Or, does the author self-cite, omit, mis-cite and/or over-cite references? Appropriate 7 Language: Does the language in article correctly, clearly and concisely express the information? Or, does the article have multiple grammatical and spelling mistakes? Acceptable format, formal and scientifically clear 8 Caveats or drawbacks: What are the caveats or drawbacks for the results? Single center results Lower sample size which might effect on statistical significance Transparency in methodology " [Collapse]

Stawarz K, Gorzelnik A, Klos W, Korzon J, Kissin F, Bienkowska-Pluta K, Stawarz G, Rusetska N, Zwoliński J. Prognostic value of clinicopathological parameters in adenoid cystic carcinoma: A retrospective cohort study. World J Clin Oncol 2026; 17(4): 116329

"This review article explores the complex relationship between nutrition, ultra‑processed food consumption, and colorectal cancer ..." [Read more]

"This review article explores the complex relationship between nutrition, ultra‑processed food consumption, and colorectal cancer development. It highlights how diets rich in additives, refined sugars, and industrial fats contribute to dysbiosis, inflammation, and oxidative stress, thereby increasing cancer risk. Conversely, dietary interventions such as fasting, caloric restriction, and ketogenic regimens show promise in reprogramming tumor metabolism and enhancing therapeutic responses. The authors emphasize that while mechanistic evidence is strong, clinical studies remain limited, heterogeneous, and often small in scale. Overall, the paper underscores the potential of personalized nutrition as a complementary strategy in colorectal cancer prevention and treatment, but stresses the need for well‑designed trials to validate safety, adherence, and long‑term outcomes." [Collapse]

Lima RSP, Sousa JDS, Neres MSO, de Sousa DJM, Martins JA, Pereira IC, da Silva ACA, Severo JS, Torres-Leal FL, da Silva MTB. Colorectal cancer therapy and nutrition: From ultra-processed consumption to metabolic reprogramming. World J Gastrointest Oncol 2026; 18(4): 115511

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Peer-Reviewers and Manuscript Statistics

Editorial board members: 2263

Peer-reviewers: 37618

Manuscripts received today: 31

Manuscript reviews today: 51

Unhandled manuscripts today: 172

Active peer-reviewers today: 2337

Reviewer acceptance today: 61

Reviewer refusals today: 73

Total accepted manuscripts: 41563

Total rejected manuscripts: 45796

Total peer-reviewers: 4862065

Total submissions: 39320