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Contents Volume 16 Issue 2 February 24, 2025

Editorial

Pancreatic cancer: Future challenges and new perspectives for an early diagnosis

Helga Bertani, Rita Conigliaro, Giuseppe Grande, Santi Mangiafico, Emanuela Dell'Aquila, Maria Marsico, Margherita Marocchi, Raffaele Lieto, Marinella Lupo, Giuseppina Pontillo, Silvia Cocca

World J Clin Oncol 16(2):97248. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.97248

Abstract (557) | Core Tip (621) | Full Article (HTML) (1823) | Figures (1-4) (459) | Full Article (PDF)-5243K (215) | Full Article with Cover (PDF)-5412K (170) | Full Article (XML)-122K (116) | Audio-915K (42) | Peer-Review Report-188K (97) | Answering Reviewers-105K (104) | Received: 05/29/2024 | Revised: 09/27/2024 | Accepted: 10/21/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (6768) | Similar Articles (445) | Timeline of Article Publication (3) | Article Quality Tracking (0) | Cite |

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Current and future perspectives in the management and treatment of colorectal cancer

Felipe Couñago, Fernando López-Campos, Evita Krumina, Sigfredo E Romero-Zoghbi

World J Clin Oncol 16(2):100807. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.100807

Abstract (507) | Core Tip (601) | Full Article (HTML) (2690) | Tables (1-2) (476) | Full Article (PDF)-434K (206) | Full Article with Cover (PDF)-599K (128) | Full Article (XML)-155K (104) | Audio-450K (12) | Peer-Review Report-176K (100) | Answering Reviewers-80K (96) | Received: 08/26/2024 | Revised: 09/30/2024 | Accepted: 10/23/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (6) | Total Visits (6267) | Similar Articles (1141) | Timeline of Article Publication (3) | Authors Evaluation (3) | Article Quality Tracking (0) | Cite |

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Minireviews

Molecular mechanism of pancreatic ductal adenocarcinoma: The heterogeneity of cancer-associated fibroblasts and key signaling pathways

Tao Yu, Cheng-Ming Zhang, Ya-Feng Deng, Yu Song, Ding Ding, Zhong-Yuan Hu

World J Clin Oncol 16(2):97007. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.97007

Abstract (526) | Core Tip (528) | Full Article (HTML) (2547) | Tables (1-2) (421) | Full Article (PDF)-465K (177) | Full Article with Cover (PDF)-632K (154) | Full Article (XML)-197K (109) | Audio-475K (14) | Peer-Review Report-220K (100) | Answering Reviewers-95K (91) | Received: 05/20/2024 | Revised: 10/04/2024 | Accepted: 11/04/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (4) | Total Visits (6098) | Similar Articles (7) | Timeline of Article Publication (3) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

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Retrospective Study

Programmed cell death 1 inhibitor sintilimab plus S-1 and gemcitabine for liver metastatic pancreatic ductal adenocarcinoma

Qing-Hua Ke, Hong-Tao Li, Yuan Ren, Seng Zhang, Peng Wan, Shi-Qiong Zhou

World J Clin Oncol 16(2):98079. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.98079

Abstract (512) | Core Tip (536) | Full Article (HTML) (1042) | Tables (1-3) (438) | Full Article (PDF)-405K (137) | Full Article with Cover (PDF)-573K (118) | Full Article (XML)-104K (104) | Audio-16522K (10) | Peer-Review Report-185K (106) | Answering Reviewers-102K (84) | Received: 06/17/2024 | Revised: 10/21/2024 | Accepted: 11/25/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (6057) | Similar Articles (85) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Observational Study

Nomogram for overall survival in ampullary adenocarcinoma using the surveillance, epidemiology, and end results database and external validation

Jia Yang, Zi-Yi Wang, Jing Chen, Yao Zhang, Lei Chen

World J Clin Oncol 16(2):95910. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.95910

Abstract (476) | Core Tip (508) | Full Article (HTML) (1165) | Figures (1-5) (371) | Tables (1-3) (366) | Full Article (PDF)-95463K (186) | Full Article with Cover (PDF)-95632K (196) | Full Article (XML)-126K (97) | Audio-466K (9) | Peer-Review Report-174K (113) | Answering Reviewers-178K (101) | Received: 04/22/2024 | Revised: 09/28/2024 | Accepted: 11/20/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (6551) | Similar Articles (120) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Prospective Study

Health anxiety and work loss in patients diagnosed with serrated polyposis syndrome: A cross sectional study

Angus Thompson, Natalie R Dierick, Louise Heiniger, Stuart N Kostalas

World J Clin Oncol 16(2):97107. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.97107

Abstract (462) | Core Tip (590) | Full Article (HTML) (1217) | Figures (1-4) (424) | Tables (1-4) (419) | Full Article (PDF)-1436K (154) | Full Article with Cover (PDF)-1603K (171) | Full Article (XML)-116K (102) | Audio-272K (9) | Peer-Review Report-453K (100) | Answering Reviewers-59K (111) | Supplementary Material-89K (87) | Received: 05/23/2024 | Revised: 09/04/2024 | Accepted: 11/08/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (5412) | Similar Articles (2) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Basic Study

Targeting STAT3 with SH-4-54 suppresses stemness and chemoresistance in cancer stem-like cells derived from colorectal cancer

Xu-Fan Zhang, Qian Chen, Qin Jiang, Qiong-Ying Hu

World J Clin Oncol 16(2):97296. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.97296

Abstract (457) | Core Tip (507) | Full Article (HTML) (1194) | Figures (1-6) (452) | Full Article (PDF)-10731K (143) | Full Article with Cover (PDF)-10898K (112) | Full Article (XML)-83K (102) | Audio-934K (9) | Peer-Review Report-220K (97) | Answering Reviewers-70K (91) | Received: 05/27/2024 | Revised: 09/26/2024 | Accepted: 11/19/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (4579) | Similar Articles (1152) | Timeline of Article Publication (4) | Article Quality Tracking (0) | Cite |

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Overexpression pattern, function, and clinical value of proteasome 26S subunit non-ATPase 6 in hepatocellular carcinoma

Jia-Liang Wei, Gang Chen, Yi-Wu Dang, Qin-Yan Su, Qian Lin, Lei Wang, Bang-Teng Chi, Rong-Quan He, Guang-Cai Zheng, Da-Tong Zeng, Yi Chen, Yu-Ping Ye, Sheng-Sheng Zhou

World J Clin Oncol 16(2):99839. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.99839

Abstract (457) | Core Tip (553) | Full Article (HTML) (1396) | Figures (1-11) (391) | Tables (1-1) (397) | Full Article (PDF)-31960K (187) | Full Article with Cover (PDF)-32127K (165) | Full Article (XML)-113K (102) | Audio-1861K (15) | Peer-Review Report-221K (102) | Answering Reviewers-205K (104) | Received: 07/31/2024 | Revised: 10/10/2024 | Accepted: 11/13/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (6754) | Similar Articles (1879) | Timeline of Article Publication (0) | Authors Evaluation (2) | Article Quality Tracking (0) | Cite |

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Scientometrics

Mapping the landscape of gastric signet ring cell carcinoma: Overcoming hurdles and charting new paths for advancement

Shu-Yuan Wang, Jing-Hang Wang, Run-Kai Chen, Zhen Yuan, Hao Cui, Bo Wei, Jian-Xin Cui

World J Clin Oncol 16(2):98983. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.98983

Abstract (602) | Core Tip (662) | Full Article (HTML) (1982) | Figures (1-6) (470) | Tables (1-6) (441) | Full Article (PDF)-15154K (149) | Full Article with Cover (PDF)-15321K (153) | Full Article (XML)-202K (99) | Audio-1037K (26) | Peer-Review Report-226K (101) | Answering Reviewers-150K (99) | Supplementary Material-3464K (110) | Received: 07/10/2024 | Revised: 09/26/2024 | Accepted: 11/13/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (4) | Total Visits (6420) | Similar Articles (16) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Correlation between gut microbiota and tumor immune microenvironment: A bibliometric and visualized study

Zheng-Jun Hu, Hui-Rong Zhu, Yong-Jie Jin, Pan Liu, Xiao-Wei Yu, Yu-Ren Zhang

World J Clin Oncol 16(2):101611. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.101611

Abstract (470) | Core Tip (459) | Full Article (HTML) (1405) | Figures (1-10) (409) | Tables (1-7) (363) | Full Article (PDF)-23001K (151) | Full Article with Cover (PDF)-23168K (166) | Full Article (XML)-167K (119) | Audio-1641K (20) | Peer-Review Report-178K (90) | Answering Reviewers-118K (92) | Received: 09/20/2024 | Revised: 11/02/2024 | Accepted: 11/25/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (5216) | Similar Articles (179) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Case Report

Denosumab combined with immunotherapy, radiotherapy, and granulocyte-macrophage colony-stimulating factor for the treatment of metastatic nasopharyngeal carcinoma: A case report

Wei-Wu Chen, Yue-Hong Kong, Li-Yuan Zhang

World J Clin Oncol 16(2):95642. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.95642

Abstract (440) | Core Tip (505) | Full Article (HTML) (1382) | Figures (1-3) (412) | Full Article (PDF)-13901K (152) | Full Article with Cover (PDF)-14069K (168) | Full Article (XML)-67K (112) | Audio-547K (14) | Peer-Review Report-225K (90) | Answering Reviewers-173K (103) | Received: 04/15/2024 | Revised: 09/28/2024 | Accepted: 10/22/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (4738) | Similar Articles (4644) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Pembrolizumab-induced Guillain-Barré syndrome in triple-negative breast cancer: A case report

Trishala Meghal, Doantrang Du, Sai Rakshith Gaddameedi, Muhammad Tayyeb, Phani Bhavana Cherukuri

World J Clin Oncol 16(2):97823. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.97823

Abstract (498) | Core Tip (538) | Full Article (HTML) (2477) | Figures (1-1) (431) | Tables (1-1) (389) | Full Article (PDF)-1579K (228) | Full Article with Cover (PDF)-1746K (169) | Full Article (XML)-78K (118) | Audio-885K (12) | Peer-Review Report-220K (106) | Answering Reviewers-84K (106) | Received: 06/10/2024 | Revised: 10/21/2024 | Accepted: 11/08/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (6610) | Similar Articles (4562) | Timeline of Article Publication (4) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

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Turning the tide: From cervical cancer's grip to complete response: A case report

Shatha Abutaha, Abdulla Alzibdeh, Issa Mohamad, Lina Wahbeh, Samer Salah, Ramiz Abuhijlih, Fawzi Abuhijla

World J Clin Oncol 16(2):98219. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.98219

Abstract (478) | Core Tip (522) | Full Article (HTML) (1191) | Figures (1-2) (358) | Full Article (PDF)-3904K (136) | Full Article with Cover (PDF)-4072K (139) | Full Article (XML)-65K (97) | Audio-319K (10) | Peer-Review Report-246K (91) | Answering Reviewers-115K (96) | Received: 06/20/2024 | Revised: 09/24/2024 | Accepted: 10/25/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (5538) | Similar Articles (4575) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Individualized treatment guided by endoscopic ultrasound-guided fine-needle aspiration for adrenocortical oncocytoma: A case report

Han Chen, Xue Jing

World J Clin Oncol 16(2):98223. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.98223

Abstract (433) | Core Tip (479) | Full Article (HTML) (944) | Figures (1-2) (390) | Tables (1-2) (413) | Full Article (PDF)-8084K (137) | Full Article with Cover (PDF)-8252K (112) | Full Article (XML)-55K (108) | Audio-1737K (13) | Peer-Review Report-220K (88) | Answering Reviewers-33K (91) | Received: 06/20/2024 | Revised: 10/01/2024 | Accepted: 11/12/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (4514) | Similar Articles (4547) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Combined BRAF G469A mutation and echinoderm microtubule associated protein like-4-anaplastic lymphoma kinase rearrangement with resistance: A case report and review of literature

Xuan Guo, Yan Liu, Yu-Ting Wang, Kan Liu, Hui Ding

World J Clin Oncol 16(2):98812. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.98812

Abstract (447) | Core Tip (484) | Full Article (HTML) (977) | Figures (1-2) (361) | Tables (1-1) (402) | Full Article (PDF)-3848K (135) | Full Article with Cover (PDF)-4016K (97) | Full Article (XML)-116K (105) | Audio-131K (18) | Peer-Review Report-219K (88) | Answering Reviewers-65K (97) | Received: 07/06/2024 | Revised: 10/13/2024 | Accepted: 10/24/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (4615) | Similar Articles (4580) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Discovery of primary lung cancer following resection of rectal cancer lung metastasis: A case report

Fei-Yan Zhou, Fang-Hua Song, Zhen-Hao Cheng, Sen Wu

World J Clin Oncol 16(2):99635. Published online Feb 24, 2025. doi: 10.5306/wjco.v16.i2.99635

Abstract (454) | Core Tip (487) | Full Article (HTML) (1408) | Figures (1-4) (423) | Full Article (PDF)-12747K (188) | Full Article with Cover (PDF)-12915K (123) | Full Article (XML)-66K (127) | Audio-835K (3) | Peer-Review Report-225K (116) | Answering Reviewers-51K (117) | Received: 07/26/2024 | Revised: 09/24/2024 | Accepted: 10/28/2024 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (5056) | Similar Articles (4773) | Timeline of Article Publication (2) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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