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Contents Volume 23 Issue 13 April 7, 2017

Editorial

Gastroesophageal reflux disease and morbid obesity: To sleeve or not to sleeve?

Mario Morino, Francisco Schlottmann, Marco G Patti, Marco E Allaix, Fabrizio Rebecchi

World J Gastroenterol 23(13):2269-2275. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2269

Abstract (1502) | Core Tip (1471) | Full Article (HTML) (5724) | Tables (1-1) (893) | Full Article (PDF)-2197K (1164) | Audio-1153K (60) | Peer-Review Report-80K (300) | Answering Reviewers-58K (448) | Received: 11/25/2016 | Revised: 01/15/2017 | Accepted: 03/15/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (45) | Total Visits (19017) | Similar Articles (47) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Review

Advanced pancreatic ductal adenocarcinoma - Complexities of treatment and emerging therapeutic options

Chandra Diwakarla, Desmond Yip, Nadine Hein, Katherine Hannan

World J Gastroenterol 23(13):2276-2285. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2276

Abstract (1634) | Core Tip (1526) | Full Article (HTML) (6507) | Figures (1-3) (665) | Full Article (PDF)-2584K (972) | Audio-1461K (74) | Peer-Review Report-73K (370) | Answering Reviewers-83K (376) | Received: 10/28/2016 | Revised: 01/20/2017 | Accepted: 03/15/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (13) | Total Visits (19721) | Similar Articles (50) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Minireviews

Indoleamine 2,3-dioxygenase: As a potential prognostic marker and immunotherapeutic target for hepatocellular carcinoma

Kashif Asghar, Asim Farooq, Bilal Zulfiqar, Muhammad Usman Rashid

World J Gastroenterol 23(13):2286-2293. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2286

Abstract (1636) | Core Tip (1466) | Full Article (HTML) (10321) | Figures (1-1) (700) | Tables (1-1) (567) | Full Article (PDF)-2361K (1021) | Audio-978K (79) | Peer-Review Report-97K (350) | Answering Reviewers-139K (494) | Received: 12/29/2016 | Revised: 02/23/2017 | Accepted: 03/15/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (27) | Total Visits (23979) | Similar Articles (1879) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Basic Study

Disruption of the TWEAK/Fn14 pathway prevents 5-fluorouracil-induced diarrhea in mice

Takuhito Sezaki, Yuki Hirata, Teruki Hagiwara, Yuki I Kawamura, Tadashi Okamura, Rieko Takanashi, Kenta Nakano, Miwa Tamura-Nakano, Linda C Burkly, Taeko Dohi

World J Gastroenterol 23(13):2294-2307. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2294

Abstract (1448) | Core Tip (1354) | Full Article (HTML) (6370) | Figures (1-7) (601) | Full Article (PDF)-5143K (782) | Audio-1442K (48) | Peer-Review Report-114K (421) | Answering Reviewers-298K (541) | Supplementary Material-214K (359) | Received: 11/28/2016 | Revised: 02/06/2017 | Accepted: 03/02/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (8) | Total Visits (19843) | Similar Articles (0) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

CMA down-regulates p53 expression through degradation of HMGB1 protein to inhibit irradiation-triggered apoptosis in hepatocellular carcinoma

Jing-Hua Wu, Jia-Pei Guo, Jun Shi, Hui Wang, Lei-Lei Li, Bin Guo, Dian-Xing Liu, Qing Cao, Zhi-Yong Yuan

World J Gastroenterol 23(13):2308-2317. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2308

Abstract (1681) | Core Tip (1295) | Full Article (HTML) (7705) | Figures (1-4) (674) | Full Article (PDF)-3605K (715) | Audio-769K (72) | Peer-Review Report-64K (325) | Answering Reviewers-71K (457) | Received: 01/09/2017 | Revised: 02/27/2017 | Accepted: 03/06/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (30) | Total Visits (20606) | Similar Articles (1924) | Timeline of Article Publication (3) | Article Quality Tracking (0) | Cite |

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Cullin 4A is associated with epithelial to mesenchymal transition and poor prognosis in perihilar cholangiocarcinoma

Tong-Jun Zhang, Dong Xue, Cheng-De Zhang, Ze-Dong Zhang, Qing-Ran Liu, Jian-Qiang Wang

World J Gastroenterol 23(13):2318-2329. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2318

Abstract (1506) | Core Tip (1308) | Full Article (HTML) (4780) | Figures (1-5) (561) | Tables (1-2) (811) | Full Article (PDF)-5269K (701) | Audio-1144K (69) | Peer-Review Report-89K (317) | Answering Reviewers-53K (485) | Received: 11/15/2016 | Revised: 01/05/2017 | Accepted: 03/02/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (7) | Total Visits (17953) | Similar Articles (309) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Notch signaling mediated by TGF-β/Smad pathway in concanavalin A-induced liver fibrosis in rats

Yi Wang, Ruo-Wu Shen, Bing Han, Zhen Li, Le Xiong, Feng-Yu Zhang, Bei-Bei Cong, Bei Zhang

World J Gastroenterol 23(13):2330-2336. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2330

Abstract (1418) | Core Tip (1289) | Full Article (HTML) (7294) | Figures (1-3) (686) | Tables (1-2) (461) | Full Article (PDF)-2771K (798) | Audio-1017K (75) | Peer-Review Report-132K (454) | Answering Reviewers-169K (2319) | Received: 12/22/2016 | Revised: 01/26/2017 | Accepted: 02/17/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (52) | Total Visits (22256) | Similar Articles (157) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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MicroRNA-145 exerts tumor-suppressive and chemo-resistance lowering effects by targeting CD44 in gastric cancer

Jian-Feng Zeng, Xiao-Qiu Ma, Lin-Pei Wang, Wei Wang

World J Gastroenterol 23(13):2337-2345. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2337

Abstract (1517) | Core Tip (1314) | Full Article (HTML) (8271) | Figures (1-4) (542) | Full Article (PDF)-2423K (556) | Audio-922K (78) | Peer-Review Report-81K (429) | Answering Reviewers-119K (351) | Received: 10/10/2016 | Revised: 01/09/2017 | Accepted: 02/08/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (46) | Total Visits (19870) | Similar Articles (8) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Case Control Study

Predictors for difficult cecal insertion in colonoscopy: The impact of obesity indices

Soo Yun Moon, Byung Chang Kim, Dae Kyung Sohn, Kyung Su Han, Bun Kim, Chang Won Hong, Bum Joon Park, Kum Hei Ryu, Ji Hyung Nam

World J Gastroenterol 23(13):2346-2354. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2346

Abstract (1412) | Core Tip (1409) | Full Article (HTML) (4983) | Figures (1-1) (515) | Tables (1-4) (523) | Full Article (PDF)-2225K (655) | Audio-1434K (40) | Peer-Review Report-133K (268) | Answering Reviewers-660K (363) | Supplementary Material-175K (294) | Received: 11/21/2016 | Revised: 01/16/2017 | Accepted: 02/17/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (27) | Total Visits (17619) | Similar Articles (45) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Retrospective Cohort Study

Impact of interferon-free antivirus therapy on lipid profiles in patients with chronic hepatitis C genotype 1b

Daisuke Endo, Kenichi Satoh, Noritomo Shimada, Atsushi Hokari, Yoshio Aizawa

World J Gastroenterol 23(13):2355-2364. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2355

Abstract (1680) | Core Tip (1416) | Full Article (HTML) (5210) | Figures (1-4) (511) | Tables (1-2) (758) | Full Article (PDF)-2441K (726) | Audio-1143K (60) | Peer-Review Report-127K (329) | Answering Reviewers-338K (468) | Received: 12/28/2016 | Revised: 02/20/2017 | Accepted: 03/15/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (44) | Total Visits (18698) | Similar Articles (98) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Retrospective Study

Transition after pediatric liver transplantation - Perceptions of adults, adolescents and parents

Norman Junge, Katarina Migal, Imeke Goldschmidt, Ulrich Baumann

World J Gastroenterol 23(13):2365-2375. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2365

Abstract (1490) | Core Tip (1274) | Full Article (HTML) (8492) | Figures (1-3) (508) | Tables (1-5) (485) | Full Article (PDF)-2274K (760) | Audio-1375K (55) | Peer-Review Report-81K (313) | Answering Reviewers-55K (466) | Received: 11/22/2016 | Revised: 01/18/2017 | Accepted: 03/15/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (20) | Total Visits (20903) | Similar Articles (8) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(1) | (0) | (0) | (0) | Open

Minimally invasive surgery for gastric cancer: A comparison between robotic, laparoscopic and open surgery

Amilcare Parisi, Daniel Reim, Felice Borghi, Ninh T Nguyen, Feng Qi, Andrea Coratti, Fabio Cianchi, Maurizio Cesari, Francesca Bazzocchi, Orhan Alimoglu, Johan Gagnière, Graziano Pernazza, Simone D’Imporzano, Yan-Bing Zhou, Juan-Santiago Azagra, Olivier Facy, Steven T Brower, Zhi-Wei Jiang, Lu Zang, Arda Isik, Alessandro Gemini, Stefano Trastulli, Alexander Novotny, Alessandra Marano, Tong Liu, Mario Annecchiarico, Benedetta Badii, Giacomo Arcuri, Andrea Avanzolini, Metin Leblebici, Denis Pezet, Shou-Gen Cao, Martine Goergen, Shu Zhang, Giorgio Palazzini, Vito D’Andrea, Jacopo Desiderio

World J Gastroenterol 23(13):2376-2384. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2376

Abstract (1573) | Core Tip (1302) | Full Article (HTML) (5877) | Tables (1-4) (538) | Full Article (PDF)-2229K (1093) | Audio-1009K (55) | Peer-Review Report-103K (493) | Answering Reviewers-76K (463) | Received: 12/11/2016 | Revised: 01/23/2017 | Accepted: 03/15/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (83) | Total Visits (20537) | Similar Articles (1313) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Clinical implication of FDG uptake of bone marrow on PET/CT in gastric cancer patients with surgical resection

Jeong Won Lee, Moon-Soo Lee, Il Kwon Chung, Myoung Won Son, Young Sin Cho, Sang Mi Lee

World J Gastroenterol 23(13):2385-2395. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2385

Abstract (1782) | Core Tip (1409) | Full Article (HTML) (6418) | Figures (1-3) (1011) | Tables (1-5) (454) | Full Article (PDF)-2868K (837) | Audio-939K (34) | Peer-Review Report-63K (324) | Answering Reviewers-151K (329) | Received: 01/11/2017 | Revised: 03/01/2017 | Accepted: 03/15/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (33) | Total Visits (20436) | Similar Articles (1299) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Observational Study

Safety and efficacy of tenofovir in chronic hepatitis B-related decompensated cirrhosis

Soon Kyu Lee, Myeong Jun Song, Seok Hyun Kim, Byung Seok Lee, Tae Hee Lee, Young Woo Kang, Suk Bae Kim, Il Han Song, Hee Bok Chae, Soon Young Ko, Jae Dong Lee

World J Gastroenterol 23(13):2396-2403. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2396

Abstract (1603) | Core Tip (1347) | Full Article (HTML) (5373) | Figures (1-4) (528) | Tables (1-5) (877) | Full Article (PDF)-2296K (719) | Audio-1183K (135) | Peer-Review Report-84K (331) | Answering Reviewers-145K (326) | Received: 01/04/2017 | Revised: 02/20/2017 | Accepted: 03/15/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (22) | Total Visits (19154) | Similar Articles (17) | Timeline of Article Publication (6) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Can mean platelet volume play a role in evaluating the severity of acute pancreatitis?

Jing-Jing Lei, Li Zhou, Qi Liu, Can Xiong, Chun-Fang Xu

World J Gastroenterol 23(13):2404-2413. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2404

Abstract (1478) | Core Tip (1304) | Full Article (HTML) (4476) | Figures (1-4) (819) | Tables (1-6) (484) | Full Article (PDF)-2373K (568) | Audio-1390K (34) | Peer-Review Report-70K (364) | Answering Reviewers-299K (307) | Received: 12/04/2016 | Revised: 01/28/2017 | Accepted: 02/17/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (25) | Total Visits (17937) | Similar Articles (260) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Prospective Study

Proposed criteria to differentiate heterogeneous eosinophilic gastrointestinal disorders of the esophagus, including eosinophilic esophageal myositis

Hiroki Sato, Nao Nakajima, Kazuya Takahashi, Go Hasegawa, Ken-ichi Mizuno, Satoru Hashimoto, Satoshi Ikarashi, Kazunao Hayashi, Yutaka Honda, Junji Yokoyama, Yuichi Sato, Shuji Terai

World J Gastroenterol 23(13):2414-2423. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2414

Abstract (1966) | Core Tip (1263) | Full Article (HTML) (5925) | Figures (1-6) (937) | Tables (1-1) (502) | Full Article (PDF)-5682K (898) | Audio-741K (62) | Peer-Review Report-77K (275) | Answering Reviewers-100K (278) | Received: 11/17/2016 | Revised: 02/27/2017 | Accepted: 03/15/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (43) | Total Visits (23015) | Similar Articles (0) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Therapeutic experience of 289 elderly patients with biliary diseases

Zong-Ming Zhang, Zhuo Liu, Li-Min Liu, Chong Zhang, Hong-Wei Yu, Bai-Jiang Wan, Hai Deng, Ming-Wen Zhu, Zi-Xu Liu, Wen-Ping Wei, Meng-Meng Song, Yue Zhao

World J Gastroenterol 23(13):2424-2434. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2424

Abstract (1588) | Core Tip (1433) | Full Article (HTML) (6812) | Figures (1-4) (540) | Tables (1-6) (495) | Full Article (PDF)-4335K (1035) | Audio-1159K (66) | Peer-Review Report-64K (405) | Answering Reviewers-100K (447) | Received: 11/13/2016 | Revised: 01/14/2017 | Accepted: 02/17/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (17) | Total Visits (21173) | Similar Articles (41) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Meta-Analysis

What is the quantitative risk of gastric cancer in the first-degree relatives of patients? A meta-analysis

Mohammad Yaghoobi, Julia McNabb-Baltar, Raheleh Bijarchi, Richard H Hunt

World J Gastroenterol 23(13):2435-2442. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2435

Abstract (1665) | Core Tip (1476) | Full Article (HTML) (6796) | Figures (1-3) (498) | Tables (1-1) (521) | Full Article (PDF)-2238K (835) | Audio-3397K (62) | Peer-Review Report-63K (354) | Answering Reviewers-62K (358) | Received: 10/30/2016 | Revised: 01/17/2017 | Accepted: 03/15/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (67) | Total Visits (18744) | Similar Articles (1921) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Case Report

Hepatic angiosarcoma with clinical and histological features of Kasabach-Merritt syndrome

Sanya Wadhwa, Tae Hun Kim, Leah Lin, Gary Kanel, Takeshi Saito

World J Gastroenterol 23(13):2443-2447. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2443

Abstract (1469) | Core Tip (1319) | Full Article (HTML) (4830) | Figures (1-4) (1013) | Full Article (PDF)-5095K (796) | Audio-933K (51) | Peer-Review Report-94K (295) | Answering Reviewers-93K (321) | Received: 10/29/2016 | Revised: 12/23/2016 | Accepted: 01/04/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (16) | Total Visits (15082) | Similar Articles (2) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Letter to the Editor

Tumor biopsy and patient enrollment in clinical trials for advanced hepatocellular carcinoma

Lorenza Rimassa, Maria Reig, Giovanni Abbadessa, Markus Peck-Radosavljevic, William Harris, Vittorina Zagonel, Davide Pastorelli, Elena Rota Caremoli, Camillo Porta, Nevena Damjanov, Hitendra Patel, Bruno Daniele, Maria Lamar, Brian Schwartz, Terri Goldberg, Armando Santoro, Jordi Bruix

World J Gastroenterol 23(13):2448-2452. Published online Apr 7, 2017. doi: 10.3748/wjg.v23.i13.2448

Abstract (1668) | Core Tip (1441) | Full Article (HTML) (4030) | Full Article (PDF)-2064K (1087) | Audio-658K (53) | Peer-Review Report-103K (378) | Answering Reviewers-74K (425) | Received: 01/20/2017 | Revised: 02/24/2017 | Accepted: 03/15/2017 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (9) | Total Visits (14890) | Similar Articles (62) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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