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Contents Volume 22 Issue 41 November 7, 2016

Editorial

Emerging role of obeticholic acid in the management of nonalcoholic fatty liver disease

Evangelia Makri, Evangelos Cholongitas, Konstantinos Tziomalos

World J Gastroenterol 22(41):9039-9043. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9039

Abstract (1678) | Core Tip (1473) | Full Article (HTML) (5367) | Figures (1-1) (631) | Full Article (PDF)-882K (949) | Audio-1173K (55) | Peer-Review Report-105K (279) | Answering Reviewers-95K (268) | Received: 07/18/2016 | Revised: 08/31/2016 | Accepted: 09/28/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (36) | Total Visits (18460) | Similar Articles (201) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Review

Concise review: Interferon-free treatment of hepatitis C virus-associated cirrhosis and liver graft infection

Nina Weiler, Stefan Zeuzem, Martin-Walter Welker

World J Gastroenterol 22(41):9044-9056. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9044

Abstract (1417) | Core Tip (1441) | Full Article (HTML) (4699) | Tables (1-3) (640) | Full Article (PDF)-1048K (645) | Audio-1009K (46) | Peer-Review Report-86K (287) | Answering Reviewers-271K (313) | Received: 05/14/2016 | Revised: 08/09/2016 | Accepted: 10/19/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (5) | Total Visits (16117) | Similar Articles (601) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Mesenchymal stromal cell-based therapy: Regulatory and translational aspects in gastroenterology

Giovanni Dothel, Emanuel Raschi, Roberto Rimondini, Fabrizio De Ponti

World J Gastroenterol 22(41):9057-9068. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9057

Abstract (1578) | Core Tip (1524) | Full Article (HTML) (4715) | Figures (1-1) (575) | Tables (1-2) (540) | Full Article (PDF)-1784K (762) | Audio-1281K (30) | Peer-Review Report-76K (302) | Answering Reviewers-81K (324) | Received: 08/01/2016 | Revised: 09/09/2016 | Accepted: 10/19/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (9) | Total Visits (18567) | Similar Articles (18) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Genetic alterations in hepatocellular carcinoma: An update

Zhao-Shan Niu, Xiao-Jun Niu, Wen-Hong Wang

World J Gastroenterol 22(41):9069-9095. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9069

Abstract (1792) | Core Tip (2290) | Full Article (HTML) (14878) | Figures (1-1) (509) | Tables (1-3) (641) | Full Article (PDF)-1636K (1449) | Audio-735K (37) | Peer-Review Report-108K (442) | Answering Reviewers-349K (365) | Received: 08/18/2016 | Revised: 09/20/2016 | Accepted: 10/19/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (144) | Total Visits (30547) | Similar Articles (1876) | Timeline of Article Publication (2) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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Minireviews

Th17 involvement in nonalcoholic fatty liver disease progression to non-alcoholic steatohepatitis

Carla Melisa Chackelevicius, Sabrina Eliana Gambaro, Claudio Tiribelli, Natalia Rosso

World J Gastroenterol 22(41):9096-9103. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9096

Abstract (1693) | Core Tip (1563) | Full Article (HTML) (8532) | Figures (1-2) (560) | Tables (1-3) (613) | Full Article (PDF)-1157K (1012) | Audio-695K (88) | Peer-Review Report-86K (347) | Answering Reviewers-92K (436) | Received: 06/17/2016 | Revised: 08/22/2016 | Accepted: 09/14/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (50) | Total Visits (22121) | Similar Articles (262) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Basic Study

Dysregulation of innate immunity in ulcerative colitis patients who fail anti-tumor necrosis factor therapy

Angela C Baird, Dominic Mallon, Graham Radford-Smith, Julien Boyer, Thierry Piche, Susan L Prescott, Ian C Lawrance, Meri K Tulic

World J Gastroenterol 22(41):9104-9116. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9104

Abstract (1803) | Core Tip (1570) | Full Article (HTML) (6058) | Figures (1-5) (539) | Tables (1-5) (583) | Full Article (PDF)-1787K (774) | Audio-2776K (53) | Peer-Review Report-86K (250) | Answering Reviewers-250K (292) | Supplementary Material-263K (354) | Received: 07/08/2016 | Revised: 08/25/2016 | Accepted: 09/28/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (25) | Total Visits (18873) | Similar Articles (421) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Altered pattern of tumor necrosis factor-alpha production in peripheral blood monocytes from Crohn's disease

Claudia Loganes, Alessia Pin, Samuele Naviglio, Martina Girardelli, Anna Monica Bianco, Stefano Martelossi, Alberto Tommasini, Elisa Piscianz

World J Gastroenterol 22(41):9117-9126. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9117

Abstract (1508) | Core Tip (1463) | Full Article (HTML) (4699) | Figures (1-5) (575) | Tables (1-2) (512) | Full Article (PDF)-1191K (695) | Audio-660K (48) | Peer-Review Report-85K (291) | Answering Reviewers-387K (415) | Received: 06/28/2016 | Revised: 08/25/2016 | Accepted: 09/14/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (7) | Total Visits (19741) | Similar Articles (590) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Esophagogastric anastomosis in rats: Improved healing by BPC 157 and L-arginine, aggravated by L-NAME

Zeljko Djakovic, Ivka Djakovic, Vedran Cesarec, Goran Madzarac, Tomislav Becejac, Goran Zukanovic, Domagoj Drmic, Lovorka Batelja, Anita Zenko Sever, Danijela Kolenc, Alen Pajtak, Nikica Knez, Mladen Japjec, Kresimir Luetic, Dinko Stancic-Rokotov, Sven Seiwerth, Predrag Sikiric

World J Gastroenterol 22(41):9127-9140. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9127

Abstract (1746) | Core Tip (1372) | Full Article (HTML) (12100) | Figures (1-9) (599) | Tables (1-1) (505) | Full Article (PDF)-2023K (753) | Audio-406K (81) | Peer-Review Report-83K (373) | Answering Reviewers-163K (346) | Received: 07/01/2016 | Revised: 08/28/2016 | Accepted: 09/28/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (21) | Total Visits (26361) | Similar Articles (90) | Timeline of Article Publication (3) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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HER2-induced metastasis is mediated by AKT/JNK/EMT signaling pathway in gastric cancer

Yiseul Choi, Young San Ko, Jinju Park, Youngsun Choi, Younghoon Kim, Jung-Soo Pyo, Bo Gun Jang, Douk Ho Hwang, Woo Ho Kim, Byung Lan Lee

World J Gastroenterol 22(41):9141-9153. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9141

Abstract (1573) | Core Tip (1401) | Full Article (HTML) (6249) | Figures (1-7) (654) | Tables (1-1) (476) | Full Article (PDF)-1813K (716) | Audio-798K (55) | Peer-Review Report-118K (363) | Answering Reviewers-252K (442) | Received: 06/29/2016 | Revised: 08/12/2016 | Accepted: 09/12/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (30) | Total Visits (20605) | Similar Articles (1289) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Retrospective Cohort Study

Effect of airplane transport of donor livers on post-liver transplantation survival

Yi Huang, Gerry MacQuillan, Leon A Adams, George Garas, Megan Collins, Albert Nwaba, Linjun Mou, Max K Bulsara, Luc Delriviere, Gary P Jeffrey

World J Gastroenterol 22(41):9154-9161. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9154

Abstract (1714) | Core Tip (1342) | Full Article (HTML) (3783) | Figures (1-4) (540) | Tables (1-3) (537) | Full Article (PDF)-1236K (533) | Audio-404K (51) | Peer-Review Report-128K (261) | Answering Reviewers-59K (257) | Received: 06/03/2016 | Revised: 07/26/2016 | Accepted: 08/23/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (5) | Total Visits (16424) | Similar Articles (2) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Retrospective Study

First-line endoscopic treatment with over-the-scope clips significantly improves the primary failure and rebleeding rates in high-risk gastrointestinal bleeding: A single-center experience with 100 cases

Hans-Jürgen Richter-Schrag, Torben Glatz, Christine Walker, Andreas Fischer, Robert Thimme

World J Gastroenterol 22(41):9162-9171. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9162

Abstract (1605) | Core Tip (1432) | Full Article (HTML) (4934) | Figures (1-2) (575) | Tables (1-6) (879) | Full Article (PDF)-1270K (777) | Audio-2635K (34) | Peer-Review Report-83K (460) | Answering Reviewers-40K (438) | Received: 06/18/2016 | Revised: 08/01/2016 | Accepted: 09/28/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (50) | Total Visits (19663) | Similar Articles (82) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Presepsin teardown - pitfalls of biomarkers in the diagnosis and prognosis of bacterial infection in cirrhosis

Maria Papp, Tamas Tornai, Zsuzsanna Vitalis, Istvan Tornai, David Tornai, Tamas Dinya, Andrea Sumegi, Peter Antal-Szalmas

World J Gastroenterol 22(41):9172-9185. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9172

Abstract (1605) | Core Tip (1596) | Full Article (HTML) (6890) | Figures (1-3) (598) | Tables (1-6) (531) | Full Article (PDF)-1267K (693) | Audio-2109K (38) | Peer-Review Report-105K (299) | Answering Reviewers-453K (322) | Received: 06/28/2016 | Revised: 08/26/2016 | Accepted: 09/28/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (19) | Total Visits (19399) | Similar Articles (281) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Impact of IL28B and OAS gene family polymorphisms on interferon treatment response in Caucasian children chronically infected with hepatitis B virus

Krzysztof Domagalski, Małgorzata Pawłowska, Agnieszka Zaleśna, Małgorzata Pilarczyk, Paweł Rajewski, Waldemar Halota, Andrzej Tretyn

World J Gastroenterol 22(41):9186-9195. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9186

Abstract (1717) | Core Tip (1259) | Full Article (HTML) (4473) | Tables (1-4) (489) | Full Article (PDF)-1119K (584) | Audio-1016K (46) | Peer-Review Report-83K (262) | Answering Reviewers-87K (261) | Received: 06/27/2016 | Revised: 08/31/2016 | Accepted: 09/28/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (14) | Total Visits (15813) | Similar Articles (275) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Simplified criteria for diagnosing superficial esophageal squamous neoplasms using Narrow Band Imaging magnifying endoscopy

Akira Dobashi, Kenichi Goda, Noboru Yoshimura, Tomohiko R Ohya, Masayuki Kato, Kazuki Sumiyama, Masato Matsushima, Shinichi Hirooka, Masahiro Ikegami, Hisao Tajiri

World J Gastroenterol 22(41):9196-9204. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9196

Abstract (1953) | Core Tip (1859) | Full Article (HTML) (5307) | Figures (1-5) (571) | Tables (1-3) (529) | Full Article (PDF)-1572K (696) | Audio-1094K (46) | Peer-Review Report-103K (331) | Answering Reviewers-416K (314) | Received: 06/21/2016 | Revised: 08/20/2016 | Accepted: 09/14/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (14) | Total Visits (19904) | Similar Articles (27) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Assessment of scoring systems for acute-on-chronic liver failure at predicting short-term mortality in patients with alcoholic hepatitis

Hee Yeon Kim, Chang Wook Kim, Tae Yeob Kim, Do Seon Song, Dong Hyun Sinn, Eileen L Yoon, Young Kul Jung, Ki Tae Suk, Sang Soo Lee, Chang Hyeong Lee, Tae Hun Kim, Jeong Han Kim, Hyung Joon Yim, Sung Eun Kim, Soon Koo Baik, Byung Seok Lee, Jae Young Jang, Young Seok Kim, Sang Gyune Kim, Jin Mo Yang, Joo Hyun Sohn, Heon Ju Lee, Seung Ha Park, Eun Hee Choi, Dong Joon Kim

World J Gastroenterol 22(41):9205-9213. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9205

Abstract (1450) | Core Tip (1413) | Full Article (HTML) (7451) | Figures (1-2) (540) | Tables (1-3) (533) | Full Article (PDF)-1253K (724) | Audio-974K (60) | Peer-Review Report-92K (257) | Answering Reviewers-110K (324) | Received: 06/24/2016 | Revised: 08/20/2016 | Accepted: 09/14/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (21) | Total Visits (20464) | Similar Articles (244) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Prospective Study

Molecular detection of Helicobacter pylori antibiotic resistance in stool vs biopsy samples

Denise E Brennan, Joseph Omorogbe, Mary Hussey, Donal Tighe, Grainne Holleran, Colm O’Morain, Sinéad M Smith, Deirdre McNamara

World J Gastroenterol 22(41):9214-9221. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9214

Abstract (1510) | Core Tip (1591) | Full Article (HTML) (5249) | Figures (1-1) (548) | Tables (1-3) (529) | Full Article (PDF)-1025K (879) | Audio-951K (59) | Peer-Review Report-94K (324) | Answering Reviewers-331K (402) | Received: 08/09/2016 | Revised: 09/27/2016 | Accepted: 10/19/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (39) | Total Visits (18523) | Similar Articles (11) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

(1) | (0) | (0) | (0) | Open

Case Report

Two cases of pancreatic ductal adenocarcinoma with intrapancreatic metastasis

Yusuke Fujita, Minoru Kitago, Yohei Masugi, Osamu Itano, Masahiro Shinoda, Yuta Abe, Taizo Hibi, Hiroshi Yagi, Yoko Fujii-Nishimura, Michiie Sakamoto, Yuko Kitagawa

World J Gastroenterol 22(41):9222-9228. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9222

Abstract (1541) | Core Tip (1467) | Full Article (HTML) (4325) | Figures (1-6) (584) | Tables (1-1) (517) | Full Article (PDF)-1944K (549) | Audio-945K (39) | Peer-Review Report-82K (311) | Answering Reviewers-122K (282) | Received: 07/12/2016 | Revised: 09/04/2016 | Accepted: 09/14/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (7) | Total Visits (16825) | Similar Articles (53) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Collision tumor of hepatocellular carcinoma and neuroendocrine carcinoma involving the liver: Case report and review of the literature

Gyu Ho Choi, Sun Young Ann, Soon Il Lee, Suk Bae Kim, Il Han Song

World J Gastroenterol 22(41):9229-9234. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9229

Abstract (1304) | Core Tip (1319) | Full Article (HTML) (5226) | Figures (1-4) (530) | Tables (1-1) (521) | Full Article (PDF)-1537K (623) | Audio-479K (47) | Peer-Review Report-92K (399) | Answering Reviewers-176K (288) | Received: 06/02/2016 | Revised: 07/21/2016 | Accepted: 08/23/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (33) | Total Visits (15971) | Similar Articles (1906) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Reoperation in an adult female with "right-sided" Hirschsprung's disease complicated by refractory hypertension and cough

Zhi-Jian Wei, Lei Huang, A-Man Xu

World J Gastroenterol 22(41):9235-9241. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9235

Abstract (1372) | Core Tip (1253) | Full Article (HTML) (9085) | Figures (1-3) (851) | Full Article (PDF)-1771K (551) | Audio-5444K (46) | Peer-Review Report-82K (263) | Answering Reviewers-124K (237) | Received: 06/27/2016 | Revised: 08/17/2016 | Accepted: 09/06/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (20010) | Similar Articles (98) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Metabolic imaging for guidance of curative treatment of isolated pelvic implantation metastasis after resection of spontaneously ruptured hepatocellular carcinoma: A case report

Bing Hao, Wei Guo, Na-Na Luo, Hao Fu, Hao-Jun Chen, Long Zhao, Hua Wu, Long Sun

World J Gastroenterol 22(41):9242-9246. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9242

Abstract (1630) | Core Tip (1444) | Full Article (HTML) (3744) | Figures (1-2) (556) | Full Article (PDF)-1076K (548) | Audio-871K (45) | Peer-Review Report-93K (327) | Answering Reviewers-233K (334) | Received: 05/08/2016 | Revised: 07/09/2016 | Accepted: 08/01/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (13844) | Similar Articles (0) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Letter to the Editor

Hepatic epithelioid hemangioendothelioma: Dilemma and challenges in the preoperative diagnosis

Hai-Jie Hu, Yan-Wen Jin, Qiu-Yang Jing, Anuj Shrestha, Nan-Sheng Cheng, Fu-Yu Li

World J Gastroenterol 22(41):9247-9250. Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9247

Abstract (1376) | Core Tip (1412) | Full Article (HTML) (4277) | Figures (1-4) (638) | Full Article (PDF)-1174K (675) | Audio-327K (64) | Peer-Review Report-79K (256) | Answering Reviewers-65K (310) | Received: 06/03/2016 | Revised: 08/09/2016 | Accepted: 08/23/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (20) | Total Visits (15005) | Similar Articles (310) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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