©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 7, 2016; 22(41): 9222-9228
Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9222
Published online Nov 7, 2016. doi: 10.3748/wjg.v22.i41.9222
Two cases of pancreatic ductal adenocarcinoma with intrapancreatic metastasis
Yusuke Fujita, Minoru Kitago, Osamu Itano, Masahiro Shinoda, Yuta Abe, Taizo Hibi, Hiroshi Yagi, Yuko Kitagawa, Department of Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan
Yohei Masugi, Yoko Fujii-Nishimura, Michiie Sakamoto, Department of Pathology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan
Author contributions: Fujita Y, Kitago M and Masugi Y wrote the paper; Masugi Y, Fujii-Nishimura Y and Sakamoto M evaluated the pathological findings; all other members equally contributed medical treatment.
Institutional review board statement: The report was approved by the Keio University Hospital Institutional Review Board.
Informed consent statement: The patients provided informed written consent prior to therapy.
Conflict-of-interest statement: All authors declare there are no conflicts-of-interest related to this article.
Correspondence to: Minoru Kitago, MD, PhD, Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. dragonpegasus@a3.keio.jp
Telephone: +81-3-53633802 Fax: +81-3-33554707
Received: July 12, 2016
Peer-review started: July 13, 2016
First decision: August 19, 2016
Revised: September 4, 2016
Accepted: September 14, 2016
Article in press: September 14, 2016
Published online: November 7, 2016
Processing time: 117 Days and 3.6 Hours
Peer-review started: July 13, 2016
First decision: August 19, 2016
Revised: September 4, 2016
Accepted: September 14, 2016
Article in press: September 14, 2016
Published online: November 7, 2016
Processing time: 117 Days and 3.6 Hours
Core Tip
Core tip: Although intrapancreatic metastasis (IPM) of pancreatic ductal adenocarcinoma has been regarded as a poor prognostic factor, few reports of IPM are available. Furthermore, the diagnostic criteria and the clinicopathological significance of IPM still need to be clarified. It should be remembered that IPM is present at a constant rate, and may be located in the remnant pancreas or in resected specimens other than the main lesion. IPM could be a cause of early recurrence. Here, we have presented two cases of IPM and provided suggestions regarding the foundation of the diagnosis of IPM.