Altered pattern of tumor necrosis factor-alpha production in peripheral blood monocytes from Crohn's disease

Table 1 Characteristics of Inflammatory bowel diseases patients included in the study

Patients	Age (yr)	Male/female	Active/remission
(n = 69)	(mean ± SD)
CD (n = 38)	13 ± 4.47	25/13	18/20
UC (n = 31)	13 ± 5.13	15/16	19/12

CD: Crohn’s disease; UC: Ulcerative colitis.

Table 2 NOD2 genotype analysis in Crohn’s disease patients

CD patient	NOD2 genotypes
	Ex. 4	Ex. 8	Ex. 11
	C>T	G>C	InsC
	R702W	G908R	L1007Pfs*2
3	C/C	G/G	InsC/-
4	T/T	G/G	-/-
7	C/T	G/G	InsC/-
14	C/C	G/C	-/-
18	C/C	G/C	InsC/-
24	C/T	G/G	-/-
25	C/C	G/C	-/-
44	C/C	G/G	InsC/-
45	C/C	G/G	InsC/-
47	C/C	G/C	InsC/-
53	C/C	G/G	InsC/-
54	C/C	G/C	-/-
63	C/C	G/G	InsC/-

Details of the three NOD2 polymorphisms (R702W, G908R, L1007Pfs*2) that were found in heterozygous or in homozygous form in 13 of the CD patients. The 23 patients who were found to be wild type are not listed in the table.