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Contents Volume 17 Issue 6 June 15, 2025

Editorial

Unveiling genetic susceptibility in esophageal squamous cell carcinoma and revolutionizing pancreatic cancer diagnosis through imaging

Sheng-Ke Zhang, Lai Jiang, Cheng-Lu Jiang, Qiang Cao, Yu-Quan Chen, Hao Chi

World J Gastrointest Oncol 17(6):102544. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.102544

Abstract (264) | Core Tip (268) | Full Article (HTML) (968) | Full Article (PDF)-390K (119) | Full Article with Cover (PDF)-632K (114) | Full Article (XML)-63K (80) | Audio-1419K (18) | Peer-Review Report-282K (73) | Answering Reviewers-174K (64) | Received: 10/21/2024 | Revised: 02/16/2025 | Accepted: 04/14/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (7) | Total Visits (2996) | Similar Articles (556) | Timeline of Article Publication (5) | Article Quality Tracking (2) | Cite |

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Kinesin family member 14 in digestive tract malignancies: Oncogenic mechanisms, clinical implications, and therapeutic prospects

Jian-Li Ge, Yu-Tong Han, Chang Qiao, De-Hui Li

World J Gastrointest Oncol 17(6):105062. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105062

Abstract (268) | Core Tip (264) | Full Article (HTML) (750) | Figures (1-1) (231) | Tables (1-1) (232) | Full Article (PDF)-1542K (103) | Full Article with Cover (PDF)-1782K (111) | Full Article (XML)-107K (78) | Audio-785K (11) | Peer-Review Report-180K (63) | Answering Reviewers-77K (71) | Received: 01/10/2025 | Revised: 03/20/2025 | Accepted: 04/08/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (3906) | Similar Articles (1) | Timeline of Article Publication (4) | Authors Evaluation (4) | Article Quality Tracking (1) | Cite |

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Prognostic value of post-neoadjuvant immunochemotherapy hypercoagulation in gastric cancer patients undergoing surgery

Meng-Jie Quan, Qiang Lin

World J Gastrointest Oncol 17(6):105085. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105085

Abstract (278) | Core Tip (258) | Full Article (HTML) (735) | Full Article (PDF)-365K (88) | Full Article with Cover (PDF)-608K (137) | Full Article (XML)-46K (65) | Audio-847K (12) | Peer-Review Report-357K (63) | Answering Reviewers-104K (55) | Received: 01/14/2025 | Revised: 04/01/2025 | Accepted: 04/10/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (2419) | Similar Articles (5) | Timeline of Article Publication (5) | Authors Evaluation (4) | Article Quality Tracking (1) | Cite |

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Review

Role, mechanism, and application of N6-methyladenosine in hepatobiliary carcinoma

Tie-Min Pei, Qing-Hui Meng, Jia Sun, Zhi-Jie Yin, Qing-Fu Lang, Chen Jia

World J Gastrointest Oncol 17(6):105140. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105140

Abstract (274) | Core Tip (287) | Full Article (HTML) (651) | Figures (1-2) (210) | Tables (1-1) (209) | Full Article (PDF)-1984K (139) | Full Article with Cover (PDF)-2225K (112) | Full Article (XML)-304K (64) | Audio-694K (11) | Peer-Review Report-167K (64) | Answering Reviewers-106K (71) | Received: 01/12/2025 | Revised: 04/01/2025 | Accepted: 04/22/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (2914) | Similar Articles (7) | Timeline of Article Publication (8) | Authors Evaluation (7) | Article Quality Tracking (1) | Cite |

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Progress of traditional Chinese medicine in the prevention and treatment of colorectal cancer

Li Mo, Yuan Wang, Xin-Yue Liang, Tao Zou, Yan Chen, Jin-Yu Tan, Jie Wen, Xiao-Hong Jian

World J Gastrointest Oncol 17(6):105690. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105690

Abstract (321) | Core Tip (341) | Full Article (HTML) (2460) | Figures (1-1) (219) | Tables (1-1) (246) | Full Article (PDF)-2341K (237) | Full Article with Cover (PDF)-2579K (215) | Full Article (XML)-509K (80) | Audio-1519K (21) | Peer-Review Report-306K (67) | Answering Reviewers-274K (76) | Received: 02/03/2025 | Revised: 03/07/2025 | Accepted: 04/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (7) | Total Visits (5545) | Similar Articles (1205) | Timeline of Article Publication (7) | Authors Evaluation (7) | Article Quality Tracking (1) | Cite |

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Application of single-cell sequencing in the study of immune cell infiltration in inflammatory bowel disease and colorectal cancer

Yan-Dong Miao, Si-Xiang Lin, Wen-Yu Luan, Zhen-Xi Xu, Hui-Min Wang, Zheng Zhang

World J Gastrointest Oncol 17(6):107382. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.107382

Abstract (257) | Core Tip (337) | Full Article (HTML) (959) | Figures (1-3) (213) | Tables (1-1) (207) | Full Article (PDF)-3640K (159) | Full Article with Cover (PDF)-3879K (170) | Full Article (XML)-442K (71) | Audio-618K (17) | Peer-Review Report-192K (69) | Answering Reviewers-139K (79) | Received: 03/21/2025 | Revised: 04/14/2025 | Accepted: 05/07/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (3525) | Similar Articles (1787) | Timeline of Article Publication (7) | Authors Evaluation (6) | Article Quality Tracking (0) | Cite |

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Minireviews

Minimally invasive lymphadenectomy for gastric cancer: Could the robotic approach provide any benefits than laparoscopy?

Franco Roviello, Marta Sandini, Natale Calomino, Stefania Angela Piccioni, Eleonora Andreucci, Mattheus Gjoka, Daniele Fusario, Gianmario Edoardo Poto, Ludovico Carbone, Daniele Marrelli

World J Gastrointest Oncol 17(6):104015. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.104015

Abstract (330) | Core Tip (311) | Full Article (HTML) (1211) | Figures (1-3) (245) | Tables (1-2) (237) | Full Article (PDF)-6768K (185) | Full Article with Cover (PDF)-7009K (140) | Full Article (XML)-283K (76) | Audio-659K (23) | Peer-Review Report-269K (66) | Answering Reviewers-180K (76) | Received: 12/06/2024 | Revised: 03/19/2025 | Accepted: 03/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (3915) | Similar Articles (1282) | Timeline of Article Publication (6) | Authors Evaluation (7) | Article Quality Tracking (2) | Cite |

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Role of myosin heavy chain 9 in gastrointestinal tumorigenesis: A comprehensive review

Ling Liu, Yao Ou, Yi-Wei Wang, Xue-Fan Zeng

World J Gastrointest Oncol 17(6):106617. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.106617

Abstract (233) | Core Tip (291) | Full Article (HTML) (928) | Figures (1-5) (213) | Tables (1-1) (211) | Full Article (PDF)-3101K (116) | Full Article with Cover (PDF)-3338K (97) | Full Article (XML)-154K (76) | Audio-1442K (10) | Peer-Review Report-258K (62) | Answering Reviewers-82K (70) | Received: 03/02/2025 | Revised: 03/28/2025 | Accepted: 05/06/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3193) | Similar Articles (0) | Timeline of Article Publication (5) | Authors Evaluation (7) | Article Quality Tracking (0) | Cite |

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Immune checkpoint inhibitors in the first-line treatment of esophageal squamous cell carcinoma: Minireview for a big shift

Giulia Massaro, Alexandra Paulet, Daniele Lavacchi, Marco Brugia, Daniele Rossini, Elisa Giommoni, Martina Catalano, Serena Pillozzi, Lorenzo Antonuzzo, Giandomenico Roviello

World J Gastrointest Oncol 17(6):106707. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.106707

Abstract (284) | Core Tip (271) | Full Article (HTML) (795) | Tables (1-1) (228) | Full Article (PDF)-441K (144) | Full Article with Cover (PDF)-683K (94) | Full Article (XML)-155K (77) | Audio-1574K (6) | Peer-Review Report-236K (66) | Answering Reviewers-92K (62) | Received: 03/04/2025 | Revised: 04/09/2025 | Accepted: 04/23/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (3125) | Similar Articles (138) | Timeline of Article Publication (3) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Artificial intelligence to predict hepatocellular carcinoma risk in cirrhosis

Imen Akkari, Hanen Akkari, Raida Harbi

World J Gastrointest Oncol 17(6):107414. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.107414

Abstract (269) | Core Tip (254) | Full Article (HTML) (756) | Tables (1-1) (201) | Full Article (PDF)-404K (126) | Full Article with Cover (PDF)-645K (153) | Full Article (XML)-90K (61) | Audio-1044K (11) | Peer-Review Report-181K (62) | Answering Reviewers-156K (63) | Received: 03/22/2025 | Revised: 04/14/2025 | Accepted: 05/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (3838) | Similar Articles (2476) | Timeline of Article Publication (4) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Progress in the study of therapeutic strategies for hepatoblastoma in children

Ran Tang, Shi-Qin Qi, Tao Zhang, Zhu-Bin Pan, Jia-Hua Xu

World J Gastrointest Oncol 17(6):107700. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.107700

Abstract (297) | Core Tip (281) | Full Article (HTML) (991) | Tables (1-3) (222) | Full Article (PDF)-451K (125) | Full Article with Cover (PDF)-692K (102) | Full Article (XML)-129K (75) | Audio-202K (16) | Peer-Review Report-286K (64) | Answering Reviewers-104K (97) | Received: 03/27/2025 | Revised: 04/10/2025 | Accepted: 05/12/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (3135) | Similar Articles (282) | Timeline of Article Publication (4) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

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Retrospective Cohort Study

Preoperative model for predicting early recurrence in hepatocellular carcinoma patients using radiomics and deep learning: A multicenter study

Yong-Hai Li, Gui-Xiang Qian, Ling Yao, Xue-Di Lei, Yu Zhu, Lei Tang, Zi-Ling Xu, Xiang-Yi Bu, Ming-Tong Wei, Jian-Lin Lu, Wei-Dong Jia

World J Gastrointest Oncol 17(6):106608. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.106608

Abstract (233) | Core Tip (270) | Full Article (HTML) (991) | Figures (1-6) (237) | Tables (1-3) (217) | Full Article (PDF)-3965K (120) | Full Article with Cover (PDF)-4208K (114) | Full Article (XML)-134K (70) | Audio-1587K (22) | Peer-Review Report-225K (60) | Answering Reviewers-181K (65) | Supplementary Material-200K (61) | Received: 03/02/2025 | Revised: 04/19/2025 | Accepted: 05/06/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (3889) | Similar Articles (1990) | Timeline of Article Publication (6) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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Evaluation of tumor budding, desmoplastic reaction, and lymphocytic infiltration in predicting survival for pancreatic ductal adenocarcinoma

Gulsum O Elpek, Ali M Tatli, Cumhur I Bassorgun, Betul Unal, Mustafa Karaca, Busra Altunay, Kubra Simsek, Aysen Yavuz, Anıl Alpsoy

World J Gastrointest Oncol 17(6):107021. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.107021

Abstract (300) | Core Tip (246) | Full Article (HTML) (679) | Figures (1-2) (216) | Tables (1-2) (249) | Full Article (PDF)-9543K (150) | Full Article with Cover (PDF)-9785K (142) | Full Article (XML)-162K (60) | Audio-329K (11) | Peer-Review Report-212K (53) | Answering Reviewers-68K (62) | Received: 03/13/2025 | Revised: 04/15/2025 | Accepted: 05/19/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (4672) | Similar Articles (60) | Timeline of Article Publication (6) | Authors Evaluation (3) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Risk of hepatocellular carcinoma according to body mass index and waist circumference in nonalcoholic fatty liver disease

Han Na Jung, Ji Hye Heo, Eun Roh, Bum Jun Kim, Minwoo Lee, Jwa-Kyung Kim, Joo-Hee Kim, Boram Han, Kyung-Do Han, Jun Goo Kang, Seong Jin Lee, Sung-Hee Ihm

World J Gastrointest Oncol 17(6):107364. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.107364

Abstract (345) | Core Tip (287) | Full Article (HTML) (912) | Figures (1-2) (274) | Tables (1-2) (240) | Full Article (PDF)-613K (99) | Full Article with Cover (PDF)-856K (102) | Full Article (XML)-103K (64) | Audio-612K (19) | Peer-Review Report-224K (57) | Answering Reviewers-37K (60) | Supplementary Material-155K (68) | Received: 03/21/2025 | Revised: 04/03/2025 | Accepted: 04/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (4040) | Similar Articles (2109) | Timeline of Article Publication (6) | Article Quality Tracking (0) | Cite |

(0) | (0) | (0) | (0) | Open

Retrospective Study

Prognostic value of preoperative fibrinogen, neutrophil-to-lymphocyte ratio, serum alpha-fetoprotein, and prealbumin for patients with primary liver cancer undergoing transarterial chemoembolization

Qi-Qi Liu, Ya-Dong Li, Jia-Xin Chen, Lin-Lin Zhang, Rong-Chun Guan, Wei Zhao, Ling-Yu Meng

World J Gastrointest Oncol 17(6):103198. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.103198

Abstract (347) | Core Tip (306) | Full Article (HTML) (916) | Figures (1-4) (235) | Tables (1-6) (259) | Full Article (PDF)-1353K (100) | Full Article with Cover (PDF)-1596K (95) | Full Article (XML)-124K (79) | Audio-267K (12) | Peer-Review Report-217K (64) | Answering Reviewers-510K (120) | Received: 02/18/2025 | Revised: 03/21/2025 | Accepted: 04/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (3684) | Similar Articles (19) | Timeline of Article Publication (7) | Article Quality Tracking (2) | Cite |

(0) | (0) | (0) | (0) | Open

Gastric cancer in children infected with Helicobacter pylori

Xia Gong, Cen Chen, Jun-Fei Shen

World J Gastrointest Oncol 17(6):103632. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.103632

Abstract (311) | Core Tip (323) | Full Article (HTML) (913) | Figures (1-3) (240) | Tables (1-1) (268) | Full Article (PDF)-787K (93) | Full Article with Cover (PDF)-1027K (73) | Full Article (XML)-82K (63) | Audio-1470K (8) | Peer-Review Report-213K (110) | Answering Reviewers-21K (54) | Received: 02/12/2025 | Revised: 03/19/2025 | Accepted: 03/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3977) | Similar Articles (1558) | Timeline of Article Publication (5) | Article Quality Tracking (1) | Cite |

(0) | (0) | (0) | (0) | Open

Significance of hemoglobin and hematocrit changes in predicting patient survival and efficacy of neoadjuvant chemotherapy for advanced gastric cancer

Ti-Hong Qiu, Hong-You Wen, Yi-Long Huang

World J Gastrointest Oncol 17(6):104592. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.104592

Abstract (333) | Core Tip (344) | Full Article (HTML) (950) | Figures (1-1) (218) | Tables (1-4) (249) | Full Article (PDF)-943K (114) | Full Article with Cover (PDF)-1185K (94) | Full Article (XML)-103K (71) | Audio-674K (38) | Peer-Review Report-213K (77) | Answering Reviewers-48K (66) | Received: 03/07/2025 | Revised: 03/31/2025 | Accepted: 04/24/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (3836) | Similar Articles (1441) | Timeline of Article Publication (9) | Authors Evaluation (6) | Article Quality Tracking (1) | Cite |

(0) | (0) | (0) | (0) | Open

Efficacy and safety of donafenib plus transarterial chemoembolization and immunotherapy for hepatocellular carcinoma

Zhi-Hao Yang, Si-Nan Liu, Fu-Ying Chu, Cheng Yang, Xiang Chen

World J Gastrointest Oncol 17(6):105170. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105170

Abstract (294) | Core Tip (335) | Full Article (HTML) (995) | Figures (1-3) (216) | Tables (1-3) (227) | Full Article (PDF)-700K (121) | Full Article with Cover (PDF)-943K (67) | Full Article (XML)-78K (59) | Audio-383K (10) | Peer-Review Report-271K (58) | Answering Reviewers-235K (61) | Received: 01/13/2025 | Revised: 03/11/2025 | Accepted: 04/18/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3922) | Similar Articles (2104) | Timeline of Article Publication (5) | Authors Evaluation (6) | Article Quality Tracking (1) | Cite |

(0) | (0) | (0) | (0) | Open

Development and validation of a nomogram for predicting postoperative venous thromboembolism risk in patients with hepatocellular carcinoma

Chun-Rong Chen, Hong-Liang Jin, Qian-Jie Xu, Yu-Liang Yuan, Zu-Hai Hu, Ya Liu, Hai-Ke Lei

World J Gastrointest Oncol 17(6):105790. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105790

Abstract (325) | Core Tip (277) | Full Article (HTML) (758) | Figures (1-4) (214) | Tables (1-1) (248) | Full Article (PDF)-1580K (101) | Full Article with Cover (PDF)-1822K (106) | Full Article (XML)-105K (66) | Audio-275K (7) | Peer-Review Report-237K (58) | Answering Reviewers-99K (51) | Received: 02/06/2025 | Revised: 04/14/2025 | Accepted: 05/16/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3374) | Similar Articles (2010) | Timeline of Article Publication (9) | Authors Evaluation (6) | Article Quality Tracking (1) | Cite |

(0) | (0) | (0) | (0) | Open

Diagnostic value of serum pepsinogen, gastrin, and carbohydrate antigens in gastric ulcer and gastric cancer

Juan Xu, Shao-Xue Li, Dong Liu, Li-Xin Chen, Xi Chen

World J Gastrointest Oncol 17(6):105931. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105931

Abstract (308) | Core Tip (320) | Full Article (HTML) (935) | Figures (1-2) (228) | Tables (1-3) (232) | Full Article (PDF)-1251K (187) | Full Article with Cover (PDF)-1493K (154) | Full Article (XML)-84K (96) | Audio-103K (11) | Peer-Review Report-224K (100) | Answering Reviewers-151K (85) | Received: 02/10/2025 | Revised: 04/09/2025 | Accepted: 05/15/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (4021) | Similar Articles (1344) | Timeline of Article Publication (6) | Authors Evaluation (5) | Article Quality Tracking (1) | Cite |

(0) | (0) | (0) | (0) | Open

Analysis of serum S100A12, soluble advanced glycation end products receptor, and gut microbiome in elderly patients with colorectal cancer

Shuai-Bo Qiao, Ming-Liao Niu, Wei-Tao Liang, Long-Jiang Zhang, Xiang Chen, Ying-Kun Zhu

World J Gastrointest Oncol 17(6):106393. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.106393

Abstract (312) | Core Tip (335) | Full Article (HTML) (927) | Figures (1-4) (211) | Tables (1-3) (218) | Full Article (PDF)-737K (104) | Full Article with Cover (PDF)-975K (199) | Full Article (XML)-110K (70) | Audio-171K (22) | Peer-Review Report-207K (56) | Answering Reviewers-169K (64) | Supplementary Material-117K (61) | Received: 03/12/2025 | Revised: 04/03/2025 | Accepted: 04/25/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (3871) | Similar Articles (1256) | Timeline of Article Publication (5) | Authors Evaluation (9) | Article Quality Tracking (1) | Cite |

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Prognostic value of hemoglobin-to-red cell distribution width ratio and inflammation markers in colorectal cancer

Esra Zeynelgil, Yakup Duzkopru, Abdulkadir Kocanoglu, Serdar Karakaya

World J Gastrointest Oncol 17(6):106603. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.106603

Abstract (327) | Core Tip (357) | Full Article (HTML) (1090) | Figures (1-1) (251) | Tables (1-2) (226) | Full Article (PDF)-1633K (118) | Full Article with Cover (PDF)-1875K (107) | Full Article (XML)-102K (73) | Audio-154K (19) | Peer-Review Report-252K (68) | Answering Reviewers-144K (65) | Received: 03/01/2025 | Revised: 03/23/2025 | Accepted: 04/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (5) | Total Visits (4029) | Similar Articles (0) | Timeline of Article Publication (7) | Authors Evaluation (6) | Article Quality Tracking (1) | Cite |

(0) | (0) | (0) | (0) | Open

Noninvasive prediction of Ki-67 expression in pancreatic cancer via contrast-enhanced ultrasound quantitative parameters: A diagnostic model study

Zi-Yi Yang, Wei-Na Wan, Lei Zhao, Si-Nong Li, Zhe Liu, Liang Sang

World J Gastrointest Oncol 17(6):107919. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.107919

Abstract (316) | Core Tip (279) | Full Article (HTML) (767) | Figures (1-7) (231) | Tables (1-9) (221) | Full Article (PDF)-9454K (109) | Full Article with Cover (PDF)-9694K (111) | Full Article (XML)-143K (65) | Audio-593K (12) | Peer-Review Report-183K (59) | Answering Reviewers-504K (66) | Received: 04/01/2025 | Revised: 04/27/2025 | Accepted: 05/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (3705) | Similar Articles (489) | Timeline of Article Publication (4) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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Impact of fibrinogen-to-albumin ratio on the long-term prognosis of patients with advanced HER2-negative gastric cancer receiving immunochemotherapy

Zhi-Yuan Yao, Jie Liu, Xiao Ma, Wan-Ting Li, Yu Shen, Yong-Zheng Cui, Yan Fang, Zheng-Xiang Han, Chun-Hua Yang

World J Gastrointest Oncol 17(6):107980. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.107980

Abstract (293) | Core Tip (311) | Full Article (HTML) (869) | Figures (1-6) (224) | Tables (1-6) (239) | Full Article (PDF)-1321K (122) | Full Article with Cover (PDF)-1563K (109) | Full Article (XML)-160K (72) | Audio-1868K (11) | Peer-Review Report-208K (82) | Answering Reviewers-112K (72) | Received: 04/01/2025 | Revised: 04/17/2025 | Accepted: 05/13/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3780) | Similar Articles (1282) | Timeline of Article Publication (5) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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Randomized Controlled Trial

Effect of gastrointestinal endoscopy center care on the psychological state and pain level of colorectal cancer patients

Yu-Hong Dai, Shi Lang Zhuo-Ma, Yu-Hua Luo

World J Gastrointest Oncol 17(6):106154. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.106154

Abstract (352) | Core Tip (288) | Full Article (HTML) (722) | Tables (1-6) (209) | Full Article (PDF)-431K (95) | Full Article with Cover (PDF)-671K (121) | Full Article (XML)-81K (69) | Audio-242K (15) | Peer-Review Report-213K (71) | Answering Reviewers-166K (68) | Received: 02/26/2025 | Revised: 04/01/2025 | Accepted: 04/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3223) | Similar Articles (1205) | Timeline of Article Publication (3) | Article Quality Tracking (1) | Cite |

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Basic Study

Role and mechanism of sarcosine dehydrogenase in the progression of gallbladder cancer through chemokine pathways

Zhen Gao, Xin Zhang, Hua He

World J Gastrointest Oncol 17(6):105016. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105016

Abstract (246) | Core Tip (262) | Full Article (HTML) (674) | Figures (1-6) (238) | Full Article (PDF)-48292K (116) | Full Article with Cover (PDF)-48533K (89) | Full Article (XML)-73K (70) | Audio-311K (14) | Peer-Review Report-214K (66) | Answering Reviewers-186K (63) | Received: 02/07/2025 | Revised: 03/10/2025 | Accepted: 04/24/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3147) | Similar Articles (48) | Timeline of Article Publication (6) | Authors Evaluation (10) | Article Quality Tracking (1) | Cite |

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Identification and validation of extracellular matrix-related genes in the progression of gastric cancer with intestinal metaplasia

Lu Wang, Meng-Han Wang, Yao-Hong Yuan, Rui-Ze Xu, Lu Bai, Mi-Zhu Wang

World J Gastrointest Oncol 17(6):105160. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105160

Abstract (290) | Core Tip (288) | Full Article (HTML) (855) | Figures (1-8) (219) | Full Article (PDF)-28930K (126) | Full Article with Cover (PDF)-29168K (79) | Full Article (XML)-107K (62) | Audio-3203K (6) | Peer-Review Report-215K (64) | Answering Reviewers-164K (65) | Received: 01/13/2025 | Revised: 03/31/2025 | Accepted: 04/23/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3408) | Similar Articles (1322) | Timeline of Article Publication (4) | Authors Evaluation (8) | Article Quality Tracking (1) | Cite |

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Endothelial Per-Arnt-Sim domain-containing protein 1 expression is correlated with poor prognosis and promotes invasion and metastasis in gastric cancer

Wang Xu, Wang Li, Jia Ru

World J Gastrointest Oncol 17(6):105213. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105213

Abstract (270) | Core Tip (283) | Full Article (HTML) (675) | Figures (1-7) (188) | Tables (1-3) (221) | Full Article (PDF)-17500K (109) | Full Article with Cover (PDF)-17740K (76) | Full Article (XML)-110K (62) | Audio-453K (8) | Peer-Review Report-308K (76) | Answering Reviewers-646K (66) | Received: 01/14/2025 | Revised: 04/19/2025 | Accepted: 05/13/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (4015) | Similar Articles (1282) | Timeline of Article Publication (7) | Authors Evaluation (11) | Article Quality Tracking (1) | Cite |

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Oxocrebanine inhibits the proliferation of hepatocellular carcinoma cells by promoting apoptosis and autophagy

Zheng-Wen Wang, Cai-Yan Pan, Cang-Long Wei, Hui Liao, Xiao-Po Zhang, Cai-Yun Zhang, Lei Yu

World J Gastrointest Oncol 17(6):105570. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105570

Abstract (277) | Core Tip (270) | Full Article (HTML) (700) | Figures (1-7) (210) | Tables (1-5) (201) | Full Article (PDF)-5520K (111) | Full Article with Cover (PDF)-5761K (105) | Full Article (XML)-101K (72) | Audio-157K (15) | Peer-Review Report-235K (63) | Answering Reviewers-79K (62) | Received: 02/18/2025 | Revised: 03/28/2025 | Accepted: 05/08/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3332) | Similar Articles (356) | Timeline of Article Publication (6) | Article Quality Tracking (1) | Cite |

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RPF2 regulates the protein kinase B/mammalian target of rapamycin pathway in the pathogenesis of Helicobacter pylori

Yan-Qiao Hua, Kai-Xin Guo, Peng Ni, Di Wang, Tong-Yan An, Yang-Ye Gao, Rong-Guang Zhang

World J Gastrointest Oncol 17(6):105664. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105664

Abstract (343) | Core Tip (278) | Full Article (HTML) (783) | Figures (1-7) (244) | Full Article (PDF)-15404K (94) | Full Article with Cover (PDF)-15643K (87) | Full Article (XML)-108K (70) | Audio-533K (14) | Peer-Review Report-310K (71) | Answering Reviewers-285K (62) | Received: 02/08/2025 | Revised: 03/25/2025 | Accepted: 05/12/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3129) | Similar Articles (0) | Timeline of Article Publication (7) | Article Quality Tracking (1) | Cite |

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Potential mechanism of Camellia luteoflora against colon adenocarcinoma: An integration of network pharmacology and molecular docking

Yu-Di Dong, Xi-Ming Wu, Wan-Qing Liu, You-Wu Hu, Hong Zhang, Wan-Di Fang, Qing Luo

World J Gastrointest Oncol 17(6):105782. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105782

Abstract (243) | Core Tip (271) | Full Article (HTML) (783) | Figures (1-7) (218) | Tables (1-3) (203) | Full Article (PDF)-20498K (116) | Full Article with Cover (PDF)-20740K (106) | Full Article (XML)-143K (89) | Audio-356K (13) | Peer-Review Report-327K (62) | Answering Reviewers-193K (109) | Supplementary Material-1401K (60) | Received: 02/06/2025 | Revised: 04/01/2025 | Accepted: 04/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (3202) | Similar Articles (40) | Timeline of Article Publication (7) | Article Quality Tracking (1) | Cite |

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Charged multivesicular body protein 7 was identified as a prognostic biomarker correlated with metastasis in colorectal cancer

Jin-Rui Wei, Yi-Na Ouyang, Meng-Ting Tang, Jia-Zhen Yuan, Pei-Li Wang, Li-He Jiang, Li-Chuan Wu

World J Gastrointest Oncol 17(6):105967. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105967

Abstract (403) | Core Tip (304) | Full Article (HTML) (754) | Figures (1-8) (225) | Tables (1-1) (215) | Full Article (PDF)-6562K (112) | Full Article with Cover (PDF)-6805K (102) | Full Article (XML)-100K (68) | Audio-1482K (10) | Peer-Review Report-273K (74) | Answering Reviewers-177K (70) | Supplementary Material-102K (64) | Received: 02/12/2025 | Revised: 04/04/2025 | Accepted: 05/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (5150) | Similar Articles (1140) | Timeline of Article Publication (11) | Authors Evaluation (11) | Article Quality Tracking (1) | Cite |

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Regulator of chromosome condensation 1 promotes hepatocellular carcinoma proliferation via cell-division-cycle-associated-8 dependent phosphoinositide 3-kinase/protein kinase B signaling

Ya-Tao Wang, Yu-Le Yong, Ze-Kun Liu, Yi-Xuan Shen, Xiang-Min Yang, Zhi-Nan Chen

World J Gastrointest Oncol 17(6):106080. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.106080

Abstract (271) | Core Tip (283) | Full Article (HTML) (875) | Figures (1-6) (217) | Tables (1-2) (262) | Full Article (PDF)-29264K (181) | Full Article with Cover (PDF)-29506K (110) | Full Article (XML)-129K (63) | Audio-150K (12) | Peer-Review Report-304K (68) | Answering Reviewers-949K (62) | Supplementary Material-291K (64) | Received: 02/15/2025 | Revised: 04/01/2025 | Accepted: 04/18/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3986) | Similar Articles (1939) | Timeline of Article Publication (5) | Authors Evaluation (8) | Article Quality Tracking (1) | Cite |

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Tumor-derived exosomal miR-425-5p and miR-135b-3p enhance colorectal cancer progression through immune suppression and vascular permeability promotion

Chun-Zai Feng, Si-Quan Zhong, Shao-Wei Ye, Zheng Zheng, Hao Sun, Shi-Hai Zhou

World J Gastrointest Oncol 17(6):106161. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.106161

Abstract (277) | Core Tip (265) | Full Article (HTML) (840) | Figures (1-5) (240) | Tables (1-2) (225) | Full Article (PDF)-9406K (113) | Full Article with Cover (PDF)-9645K (88) | Full Article (XML)-120K (66) | Audio-3145K (12) | Peer-Review Report-226K (72) | Answering Reviewers-311K (80) | Supplementary Material-1390K (63) | Received: 02/18/2025 | Revised: 03/24/2025 | Accepted: 04/22/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (4) | Total Visits (3984) | Similar Articles (1142) | Timeline of Article Publication (5) | Article Quality Tracking (1) | Cite |

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Meta-Analysis

Transarterial chemoembolization combined with lenvatinib vs transarterial chemoembolization combined with sorafenib for unresectable hepatocellular carcinoma: A systematic review and meta-analysis

Wei Zhang, Hua Fu, Zi-Rong Liu, Lin Xu, Xu Che, Yan-Ting Ning, Zheng-Yin Zhan, Guo-Chao Zhou

World J Gastrointest Oncol 17(6):105887. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105887

Abstract (342) | Core Tip (339) | Full Article (HTML) (980) | Figures (1-2) (233) | Tables (1-4) (228) | Full Article (PDF)-1361K (117) | Full Article with Cover (PDF)-1603K (95) | Full Article (XML)-128K (67) | Audio-412K (18) | Peer-Review Report-211K (59) | Answering Reviewers-183K (66) | Supplementary Material-1457K (64) | Received: 02/09/2025 | Revised: 03/25/2025 | Accepted: 04/23/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3877) | Similar Articles (2556) | Timeline of Article Publication (6) | Article Quality Tracking (1) | Cite |

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Scientometrics

Global scientific trends on hepatocellular carcinoma research from 2004 to 2023: A bibliometric and visualized analysis

Li-Qi Shang, Hao-Xin Guo, Peng Wang, Xiao-Han Sun, Jia-Qi You, Jun-Ting Ma, Lu-Ke Wang, Jia-Xi Liu, Zhong-Qing Wang, Hai-Bo Shao

World J Gastrointest Oncol 17(6):105781. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.105781

Abstract (313) | Core Tip (269) | Full Article (HTML) (979) | Figures (1-8) (261) | Tables (1-3) (259) | Full Article (PDF)-10419K (133) | Full Article with Cover (PDF)-10658K (211) | Full Article (XML)-162K (95) | Audio-4091K (11) | Peer-Review Report-265K (101) | Answering Reviewers-246K (114) | Received: 02/06/2025 | Revised: 03/22/2025 | Accepted: 04/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (4235) | Similar Articles (1876) | Timeline of Article Publication (5) | Authors Evaluation (6) | Article Quality Tracking (1) | Cite |

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Case Report

Molecular surveillance-informed personalized multidisciplinary therapy achieves prolonged survival in a patient with Lynch syndrome-associated colorectal cancer: A case report

Xin-Xin Xu, Yun-He Gao, Cheng-Zhou Du, Xiao-Xin Gao, Peng Chen, Rui-Fang Fan, Hong-Tao Li, Zhi Qiao

World J Gastrointest Oncol 17(6):106316. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.106316

Abstract (239) | Core Tip (246) | Full Article (HTML) (728) | Figures (1-4) (191) | Full Article (PDF)-2733K (128) | Full Article with Cover (PDF)-2974K (120) | Full Article (XML)-48K (61) | Audio-460K (12) | Peer-Review Report-184K (55) | Answering Reviewers-149K (58) | Received: 02/21/2025 | Revised: 03/27/2025 | Accepted: 04/22/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (2920) | Similar Articles (5690) | Timeline of Article Publication (5) | Article Quality Tracking (1) | Cite |

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Long-term survival of a patient with colorectal cancer with peritoneal carcinomatosis and low completeness of cytoreduction score: A case report

Jung Wook Suh, Jae Won Jo, Dong-Guk Park

World J Gastrointest Oncol 17(6):106846. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.106846

Abstract (281) | Core Tip (266) | Full Article (HTML) (3368) | Figures (1-4) (261) | Full Article (PDF)-7070K (135) | Full Article with Cover (PDF)-7312K (100) | Full Article (XML)-77K (61) | Audio-2159K (8) | Peer-Review Report-185K (60) | Answering Reviewers-459K (70) | Received: 03/08/2025 | Revised: 03/27/2025 | Accepted: 04/27/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (5957) | Similar Articles (5701) | Timeline of Article Publication (3) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

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Extensive bone metastases from an occult gastric primary: A case report

Chao-Bo Jin, Yong-Sheng Li, Juan Zhang, Jian Wu, Wei-Jing Tao

World J Gastrointest Oncol 17(6):106848. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.106848

Abstract (303) | Core Tip (274) | Full Article (HTML) (953) | Figures (1-4) (247) | Full Article (PDF)-11626K (129) | Full Article with Cover (PDF)-11869K (119) | Full Article (XML)-61K (60) | Audio-2522K (11) | Peer-Review Report-225K (66) | Answering Reviewers-41K (65) | Received: 03/12/2025 | Revised: 04/09/2025 | Accepted: 05/20/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3172) | Similar Articles (4539) | Timeline of Article Publication (5) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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Primary squamous cell carcinoma of the descending colon with pancreatic metastasis: A case report

Rui-Rui Hu, Mei Liu, Hong-Yun Li

World J Gastrointest Oncol 17(6):107272. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.107272

Abstract (245) | Core Tip (230) | Full Article (HTML) (867) | Figures (1-3) (204) | Full Article (PDF)-43464K (108) | Full Article with Cover (PDF)-43706K (112) | Full Article (XML)-50K (72) | Audio-808K (10) | Peer-Review Report-210K (66) | Answering Reviewers-974K (69) | Received: 03/19/2025 | Revised: 04/07/2025 | Accepted: 04/22/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (3064) | Similar Articles (4541) | Timeline of Article Publication (2) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

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Descending duodenal adenocarcinoma treated with pembrolizumab resulting in complete clinical response: A case report and literature review

Xiang-Lei Kong, Xi-Wei Lu, Si-Qi Dong, Jiao Liu, Lei Zheng, Lan-Lan Chen, Zi-Hui An, Li-Ming Gao, Jun-Li Cao

World J Gastrointest Oncol 17(6):107568. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.107568

Abstract (297) | Core Tip (276) | Full Article (HTML) (1172) | Figures (1-3) (211) | Full Article (PDF)-6042K (112) | Full Article with Cover (PDF)-6284K (95) | Full Article (XML)-112K (60) | Audio-369K (11) | Peer-Review Report-242K (57) | Answering Reviewers-192K (61) | Received: 03/26/2025 | Revised: 04/16/2025 | Accepted: 05/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (3312) | Similar Articles (4544) | Timeline of Article Publication (5) | Article Quality Tracking (0) | Cite |

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Letter to the Editor

Prognostic impact of inflammatory and nutritional markers in colorectal cancer patients with peritoneal metastasis

Zhao Cai, Wei-De Dai, Xiong-Wei Cai

World J Gastrointest Oncol 17(6):100010. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.100010

Abstract (266) | Core Tip (276) | Full Article (HTML) (843) | Full Article (PDF)-373K (110) | Full Article with Cover (PDF)-616K (128) | Full Article (XML)-60K (59) | Audio-227K (7) | Peer-Review Report-221K (65) | Answering Reviewers-140K (56) | Received: 08/07/2024 | Revised: 01/23/2025 | Accepted: 02/11/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (2973) | Similar Articles (1151) | Timeline of Article Publication (4) | Article Quality Tracking (2) | Cite |

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Esophageal squamous cell carcinoma susceptibility of activin A receptor type 1C variants in Chinese population

Shashank Kumar

World J Gastrointest Oncol 17(6):102687. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.102687

Abstract (279) | Core Tip (243) | Full Article (HTML) (667) | Full Article (PDF)-354K (76) | Full Article with Cover (PDF)-597K (81) | Full Article (XML)-36K (67) | Audio-1208K (6) | Peer-Review Report-476K (63) | Answering Reviewers-108K (65) | Received: 10/25/2024 | Revised: 01/28/2025 | Accepted: 02/11/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (2521) | Similar Articles (1) | Timeline of Article Publication (3) | Authors Evaluation (1) | Article Quality Tracking (2) | Cite |

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Unravelling the potential of plasma DNA methylation in the detection and surveillance of esophageal cancer

Jitesh Arora, Mahmoud Nassar, Bahaaeldin Baraka

World J Gastrointest Oncol 17(6):103333. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.103333

Abstract (294) | Core Tip (253) | Full Article (HTML) (612) | Full Article (PDF)-337K (74) | Full Article with Cover (PDF)-581K (91) | Full Article (XML)-22K (56) | Audio-229K (9) | Peer-Review Report-246K (62) | Answering Reviewers-100K (69) | Received: 11/15/2024 | Revised: 02/09/2025 | Accepted: 02/19/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (2460) | Similar Articles (161) | Timeline of Article Publication (3) | Article Quality Tracking (1) | Cite |

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Elevating surgical standards: The role of intraperitoneal isoperistaltic side-to-side anastomosis in colon cancer surgery

Sung Uk Bae

World J Gastrointest Oncol 17(6):106645. Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.106645

Abstract (239) | Core Tip (296) | Full Article (HTML) (741) | Figures (1-2) (201) | Full Article (PDF)-7676K (141) | Full Article with Cover (PDF)-7920K (95) | Full Article (XML)-38K (84) | Audio-297K (9) | Peer-Review Report-225K (68) | Answering Reviewers-35K (62) | Received: 03/05/2025 | Revised: 04/11/2025 | Accepted: 05/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3014) | Similar Articles (192) | Timeline of Article Publication (7) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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