©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jun 15, 2025; 17(6): 107272
Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.107272
Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.107272
Primary squamous cell carcinoma of the descending colon with pancreatic metastasis: A case report
Rui-Rui Hu, Mei Liu, Hong-Yun Li, Department of Gastroenterology, Jining No. 1 People’s Hospital, Jining 272000, Shandong Province, China
Co-first authors: Rui-Rui Hu and Mei Liu.
Author contributions: Hu RR and Liu M were responsible for conception and design of the research, acquisition of data, analysis and interpretation of the data, and writing of the manuscript, they contributed equally as co-first authors; Li HY was responsible for critical revision of the manuscript for intellectual content.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Hong-Yun Li, MD, Chief Physician, Department of Gastroenterology, Jining No. 1 People’s Hospital, No. 6 Jiankang Road, Jining 272000, Shandong Province, China. xhlhy2008@163.com
Received: March 20, 2025
Revised: April 7, 2025
Accepted: April 22, 2025
Published online: June 15, 2025
Processing time: 86 Days and 11.7 Hours
Revised: April 7, 2025
Accepted: April 22, 2025
Published online: June 15, 2025
Processing time: 86 Days and 11.7 Hours
Core Tip
Core Tip: This case represents the first documented primary squamous cell carcinoma of the descending colon with pancreatic metastasis, highlighting the dual rarity of both the primary site and metastatic behavior. It underscores the challenges in managing this aggressive malignancy, including rare metastatic patterns and severe postoperative complications, while providing critical insights for optimizing multidisciplinary therapeutic strategies in colorectal squamous cell carcinoma.