Editorial
                    
                        
                                Importance of early detection in multiple endocrine neoplasia type 1: Clinical insights and future directions 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):100013.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.100013
                            
                            
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                                            Received: 08/05/2024
                                        
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                                            Revised: 01/11/2025
                                        
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                                            Accepted: 02/18/2025
                                        
                                
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                                World J Gastrointest Oncol
                                17(4):101661.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.101661
                            
                            
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                                            Received: 09/23/2024
                                        
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                                            Revised: 01/06/2025
                                        
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                                            Accepted: 01/20/2025
                                        
                                
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                                World J Gastrointest Oncol
                                17(4):101832.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.101832
                            
                            
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                                            Received: 09/27/2024
                                        
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                                            Revised: 01/26/2025
                                        
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                                            Accepted: 02/11/2025
                                        
                                
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                                Precision medicine in the prediction of metachronous liver metastasis in rectal cancer: Applications and challenges 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):102469.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.102469
                            
                            
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                                            Received: 10/18/2024
                                        
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                                            Revised: 01/20/2025
                                        
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                                            Accepted: 01/22/2025
                                        
                                
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                                World J Gastrointest Oncol
                                17(4):102831.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.102831
                            
                            
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                                            Received: 11/05/2024
                                        
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                                            Revised: 01/17/2025
                                        
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                                            Accepted: 02/05/2025
                                        
                                
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                                Understanding metastatic patterns in gastric cancer: Insights from lymph node distribution and pathology 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):103709.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103709
                            
                            
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                                            Received: 11/27/2024
                                        
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                                            Revised: 01/26/2025
                                        
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                                            Accepted: 02/17/2025
                                        
                                
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                        Review
                    
                        
                                World J Gastrointest Oncol
                                17(4):103591.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103591
                            
                            
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                                            Received: 11/27/2024
                                        
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                                            Revised: 01/24/2025
                                        
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                                            Accepted: 02/25/2025
                                        
                                
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                        Case Control Study
                    
                        
                                Investigation of high-mobility group box 1 variants with lymph node status and colorectal cancer risk 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):102584.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.102584
                            
                            
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                                                Supplementary Material-4141K (59)
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                                            Received: 10/23/2024
                                        
                                        |
                                        
                                            Revised: 12/31/2024
                                        
                                        |
                                        
                                            Accepted: 01/22/2025
                                        
                                
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                        Retrospective Cohort Study
                    
                        
                                Idarubicin-transarterial chemoembolization combined with gemcitabine plus cisplatin for unresectable intrahepatic cholangiocarcinoma 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):103776.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103776
                            
                            
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                                            Received: 11/29/2024
                                        
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                                            Revised: 01/12/2025
                                        
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                                            Accepted: 02/07/2025
                                        
                                
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                                World J Gastrointest Oncol
                                17(4):104455.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.104455
                            
                            
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                                            Received: 12/24/2024
                                        
                                        |
                                        
                                            Revised: 01/20/2025
                                        
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                                            Accepted: 02/07/2025
                                        
                                
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                        Retrospective Study
                    
                        
                                World J Gastrointest Oncol
                                17(4):100089.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.100089
                            
                            
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                                            Received: 08/07/2024
                                        
                                        |
                                        
                                            Revised: 12/05/2024
                                        
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                                            Accepted: 02/05/2025
                                        
                                
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                                Immune checkpoint inhibitors plus anti-angiogenesis in patients with resected high-risk hepatitis B virus-associated hepatocellular carcinoma 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):101371.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.101371
                            
                            
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                                                Supplementary Material-670K (65)
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                                            Received: 09/12/2024
                                        
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                                            Revised: 01/25/2025
                                        
                                        |
                                        
                                            Accepted: 02/13/2025
                                        
                                
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                                World J Gastrointest Oncol
                                17(4):101487.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.101487
                            
                            
                                Abstract (336)
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                                            Received: 09/16/2024
                                        
                                        |
                                        
                                            Revised: 12/10/2024
                                        
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                                            Accepted: 01/22/2025
                                        
                                
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                                Comparing transarterial chemoembolization alone to combined transarterial chemoembolization and radiofrequency ablation in primary hepatocellular carcinoma treatment 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):102038.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.102038
                            
                            
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                                                Answering Reviewers-337K (62)
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                                            Received: 10/06/2024
                                        
                                        |
                                        
                                            Revised: 01/08/2025
                                        
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                                            Accepted: 01/21/2025
                                        
                                
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                                World J Gastrointest Oncol
                                17(4):102085.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.102085
                            
                            
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                                                Answering Reviewers-160K (62)
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                                            Received: 10/08/2024
                                        
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                                            Revised: 02/05/2025
                                        
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                                            Accepted: 02/24/2025
                                        
                                
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                                Using bioinformatics methods to elucidate fatty acid-binding protein 4 as a potential biomarker for colon adenocarcinoma 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):103113.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103113
                            
                            
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                                            Received: 11/12/2024
                                        
                                        |
                                        
                                            Revised: 01/07/2025
                                        
                                        |
                                        
                                            Accepted: 02/14/2025
                                        
                                
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                                Subclassification scheme for adenocarcinomas of the esophagogastric junction and prognostic analysis based on clinicopathological features 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):103455.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103455
                            
                            
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                                            Received: 11/21/2024
                                        
                                        |
                                        
                                            Revised: 01/11/2025
                                        
                                        |
                                        
                                            Accepted: 01/21/2025
                                        
                                
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                                Caregiver-involved nutritional support and mindfulness training for patients with gastrointestinal cancer: Effects on malnutrition risk and mood 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):103515.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103515
                            
                            
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                                            Received: 11/21/2024
                                        
                                        |
                                        
                                            Revised: 12/16/2024
                                        
                                        |
                                        
                                            Accepted: 01/20/2025
                                        
                                
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                                Clinical observation of nivolumab combined with cabozantinib in the treatment of advanced hepatocellular carcinoma 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):103631.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103631
                            
                            
                                Abstract (277)
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                                        |
                                        
                                            Received: 11/25/2024
                                        
                                        |
                                        
                                            Revised: 12/25/2024
                                        
                                        |
                                        
                                            Accepted: 02/07/2025
                                        
                                
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                                Detecting plasma SHOX2, HOXA9, SEPTIN9, and RASSF1A methylation and circulating cancer cells for cholangiocarcinoma clinical diagnosis and monitoring 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):104253.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.104253
                            
                            
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                                        |
                                        
                                            Received: 12/14/2024
                                        
                                        |
                                        
                                            Revised: 01/17/2025
                                        
                                        |
                                        
                                            Accepted: 02/25/2025
                                        
                                
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                        Clinical Trials Study
                    
                        
                                Intraperitoneal perfusion of endostatin improves the effectiveness and prolongs the prognosis of patients with gastric cancer 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):103131.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103131
                            
                            
                                Abstract (272)
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                                                Answering Reviewers-110K (63)
                                        |
                                        
                                            Received: 11/09/2024
                                        
                                        |
                                        
                                            Revised: 01/02/2025
                                        
                                        |
                                        
                                            Accepted: 02/18/2025
                                        
                                
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                                Efficacy and safety of early pancreatic duct stenting for unresectable pancreatic cancer: A randomized controlled trial 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):103311.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103311
                            
                            
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                                                Answering Reviewers-147K (76)
                                        |
                                        
                                            Received: 11/15/2024
                                        
                                        |
                                        
                                            Revised: 01/01/2025
                                        
                                        |
                                        
                                            Accepted: 02/10/2025
                                        
                                
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                                Combining immune checkpoint inhibitors with standard treatment regimens in advanced human epidermal growth factor receptor-2 positive gastric cancer patients 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):103855.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103855
                            
                            
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                                        |
                                        
                                            Received: 12/20/2024
                                        
                                        |
                                        
                                            Revised: 01/12/2025
                                        
                                        |
                                        
                                            Accepted: 02/07/2025
                                        
                                
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                        Observational Study
                    
                        
                                Usefulness of shear-wave elastography for detection of lymph node metastasis in esophageal and gastric cancer 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):101925.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.101925
                            
                            
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                                                Answering Reviewers-303K (68)
                                        |
                                        
                                            Received: 10/01/2024
                                        
                                        |
                                        
                                            Revised: 01/17/2025
                                        
                                        |
                                        
                                            Accepted: 02/05/2025
                                        
                                
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                        Prospective Study
                    
                        
                                World J Gastrointest Oncol
                                17(4):103029.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103029
                            
                            
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                                            Received: 11/05/2024
                                        
                                        |
                                        
                                            Revised: 12/29/2024
                                        
                                        |
                                        
                                            Accepted: 01/20/2025
                                        
                                
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                                Oesophageal cancer-specific mortality risk and public health insurance: Prospective cohort study from China 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):103629.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103629
                            
                            
                                Abstract (295)
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                                        |
                                        
                                            Received: 11/25/2024
                                        
                                        |
                                        
                                            Revised: 01/09/2025
                                        
                                        |
                                        
                                            Accepted: 02/08/2025
                                        
                                
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                        Basic Study
                    
                        
                                Snail family transcriptional repressor 1 radiosensitizes esophageal cancer via epithelial-mesenchymal transition signaling: From bioinformatics to integrated study 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):97644.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.97644
                            
                            
                                Abstract (260)
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                                                Peer-Review Report-262K (66)
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                                                Answering Reviewers-112K (61)
                                        |
                                        
                                            Received: 06/04/2024
                                        
                                        |
                                        
                                            Revised: 12/09/2024
                                        
                                        |
                                        
                                            Accepted: 01/15/2025
                                        
                                
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                                Impact of SLC16A8 on tumor microenvironment and angiogenesis in colorectal cancer: New therapeutic target insights 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):99188.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.99188
                            
                            
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                                                Full Article (PDF)-33176K (91)
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                                        |
                                        
                                            Received: 07/16/2024
                                        
                                        |
                                        
                                            Revised: 11/08/2024
                                        
                                        |
                                        
                                            Accepted: 01/15/2025
                                        
                                
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                                Plasma extracellular cold inducible RNA-binding protein levels are elevated for 1 month post-colectomy which may promote metastases 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):100678.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.100678
                            
                            
                                Abstract (271)
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                                            Received: 08/22/2024
                                        
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                                MEX3A promotes cell proliferation by regulating the RORA/β-catenin pathway in hepatocellular carcinoma 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):102084.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.102084
                            
                            
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                                            Received: 10/10/2024
                                        
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                                            Revised: 01/27/2025
                                        
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                                            Accepted: 02/14/2025
                                        
                                
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                                Centromere protein A knockdown inhibits rectal cancer through O6-methylguanine DNA methyltransferase/protein tyrosine phosphatase nonreceptor type 4 axis 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):102619.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.102619
                            
                            
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                                            Received: 10/23/2024
                                        
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                                            Revised: 01/07/2025
                                        
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                                            Accepted: 02/25/2025
                                        
                                
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                                F-box protein 22: A prognostic biomarker for colon cancer associated with immune infiltration and chemotherapy resistance 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):102913.
                                Published online Apr 15, 2025.
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                                            Received: 11/28/2024
                                        
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                                            Revised: 01/10/2025
                                        
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                                            Accepted: 02/21/2025
                                        
                                
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                                Identification of key hub genes associated with anti-gastric cancer effects of lotus plumule based on machine learning algorithms 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):103048.
                                Published online Apr 15, 2025.
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                                            Received: 11/06/2024
                                        
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                                            Revised: 12/11/2024
                                        
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                                            Accepted: 01/16/2025
                                        
                                
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                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103679
                            
                            
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                                            Received: 11/26/2024
                                        
                                        |
                                        
                                            Revised: 01/16/2025
                                        
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                                            Accepted: 02/11/2025
                                        
                                
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                                Nitric oxide synthase 1 inhibits the progression of esophageal cancer through interacting with nitric oxide synthase 1 adaptor protein 
                            
                            
                            
                            
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                                17(4):103843.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103843
                            
                            
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                                            Received: 12/02/2024
                                        
                                        |
                                        
                                            Revised: 01/22/2025
                                        
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                                            Accepted: 02/17/2025
                                        
                                
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                                Tetramethylpyrazine induces reactive oxygen species-based mitochondria-mediated apoptosis in colon cancer cells 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):104922.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.104922
                            
                            
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                                            Received: 01/08/2025
                                        
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                                            Revised: 01/26/2025
                                        
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                                            Accepted: 02/21/2025
                                        
                                
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                                Trends in nanomedicine for colorectal cancer treatment: Bibliometric and visualization analysis (2010-2024) 
                            
                            
                            
                            
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                                17(4):102438.
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                                            Received: 10/17/2024
                                        
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                                            Revised: 12/25/2024
                                        
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                                            Accepted: 02/05/2025
                                        
                                
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                                Pancreatic neuroendocrine neoplasms coexisting with biliary intraductal papillary mucinous neoplasm: A case report and review of literature 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):100497.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.100497
                            
                            
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                                        |
                                        
                                            Received: 08/19/2024
                                        
                                        |
                                        
                                            Revised: 12/06/2024
                                        
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                                            Accepted: 02/25/2025
                                        
                                
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                                World J Gastrointest Oncol
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                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.100526
                            
                            
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                                            Received: 08/19/2024
                                        
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                                            Revised: 12/16/2024
                                        
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                                            Accepted: 01/23/2025
                                        
                                
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                                Curative endoscopic submucosal dissection for esophageal squamous cell carcinoma after chemoradiotherapy for pharyngeal cancer: A case report 
                            
                            
                            
                            
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                                Published online Apr 15, 2025.
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                                            Received: 09/04/2024
                                        
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                                            Revised: 01/01/2025
                                        
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                                            Accepted: 01/21/2025
                                        
                                
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                                World J Gastrointest Oncol
                                17(4):102021.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.102021
                            
                            
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                                            Received: 10/05/2024
                                        
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                                            Revised: 01/26/2025
                                        
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                                            Accepted: 02/18/2025
                                        
                                
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                                Quadruple therapy with immunotherapy and chemotherapy as first-line conversion treatment for unresectable advanced gastric adenocarcinoma: A case report 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):102258.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.102258
                            
                            
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                                            Received: 10/13/2024
                                        
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                                            Revised: 01/20/2025
                                        
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                                            Accepted: 02/24/2025
                                        
                                
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                                Precision treatment for human epidermal growth factor receptor 2-amplified advanced rectal cancer: A case report 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):102690.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.102690
                            
                            
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                                            Received: 10/25/2024
                                        
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                                            Revised: 01/23/2025
                                        
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                                            Accepted: 02/17/2025
                                        
                                
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                                Intestinal obstruction caused by early stage primary ileum adenocarcinoma: A case report and review of literature 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):104919.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.104919
                            
                            
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                                            Received: 01/08/2025
                                        
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                                            Revised: 02/06/2025
                                        
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                                            Accepted: 02/25/2025
                                        
                                
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                        Letter to the Editor
                    
                        
                                Natural products and cancer: The urgent need to bridge the gap between preclinical and clinical research 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):100484.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.100484
                            
                            
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                                            Received: 08/17/2024
                                        
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                                            Revised: 01/20/2025
                                        
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                                            Accepted: 01/27/2025
                                        
                                
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                                World J Gastrointest Oncol
                                17(4):101528.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.101528
                            
                            
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                                            Received: 09/18/2024
                                        
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                                            Revised: 12/31/2024
                                        
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                                            Accepted: 01/08/2025
                                        
                                
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                                World J Gastrointest Oncol
                                17(4):102324.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.102324
                            
                            
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                                            Received: 10/14/2024
                                        
                                        |
                                        
                                            Revised: 01/10/2025
                                        
                                        |
                                        
                                            Accepted: 01/16/2025
                                        
                                
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                                World J Gastrointest Oncol
                                17(4):103128.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103128
                            
                            
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                                            Received: 11/11/2024
                                        
                                        |
                                        
                                            Revised: 01/10/2025
                                        
                                        |
                                        
                                            Accepted: 01/14/2025
                                        
                                
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                                World J Gastrointest Oncol
                                17(4):103480.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.103480
                            
                            
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                                            Received: 11/20/2024
                                        
                                        |
                                        
                                            Revised: 01/20/2025
                                        
                                        |
                                        
                                            Accepted: 01/23/2025
                                        
                                
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                                Personalized treatment selection in colorectal cancer with peritoneal metastasis: Do we need statistically validated indicators or cultural shift? 
                            
                            
                            
                            
                                World J Gastrointest Oncol
                                17(4):104110.
                                Published online Apr 15, 2025.
                                doi: 10.4251/wjgo.v17.i4.104110
                            
                            
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                                            Received: 12/09/2024
                                        
                                        |
                                        
                                            Revised: 01/03/2025
                                        
                                        |
                                        
                                            Accepted: 01/08/2025
                                        
                                
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