Nitric oxide synthase 1 inhibits the progression of esophageal cancer through interacting with nitric oxide synthase 1 adaptor protein

Table 1 Molecular functions of NOS1 gene

GO ID	Qualified GO term	Evidence
0004517	Nitric-oxide synthase activity	IDA, ISS, IBA, TAS
0005246	Calcium channel regulator activity	TAS
0005515	Protein binding	IPI
0005516	Calmodulin binding	IEA
0010181	Flavin mononucleotide binding	ISS, IBA
0016491	Oxidoreductase activity	IEA
0017080	Sodium channel regulator activity	ISS
0020037	Heme binding	ISS
0034617	Tetrahydrobiopterin binding	NAS
0034618	Arginine binding	TAS
0044325	Transmembrane transporter binding	ISS, TAS
0046870	Cadmium ion binding	ISS
0046872	Metal ion binding	IEA
0048306	Calcium-dependent protein binding	ISS
0050660	Flavin adenine dinucleotide binding	ISS, IBA
0050661	NADP binding	ISS
0097110	Scaffold protein binding	ISS

GO: Gene ontology; IDA: Inferred from direct assay; ISS: Inferred from sequence or structural; IBA: Inferred from biological aspect of ancestor; TAS: Traceable author statement; IPI: Inferred from physical interaction; IEA: Inferred from electronic annotation; NAS: Non-traceable author statement.