Usefulness of shear-wave elastography for detection of lymph node metastasis in esophageal and gastric cancer

Table 1 Patient background characteristics and pathological findings for esophageal cancer

Characteristic
Age: Minimum/maximum/median (years)	50	84	71
Sex: Men/women	13	5
Position: Ut/Mt/Lt/EGJ	3	10	2	3
Neoadjuvant chemotherapy: Yes/no	12	6
Chemotherapy regimen: DCF/FP/5-FU + CDGP	7	2	3
Pathological histology of primary disease: Well/mod/por/tub2/other	3	9	2	2	2
pT0/T1/T2/T3/T4	1	5	3	6	3
pN0/N1/N2/N3	10	3	3	2
pStage 0	1
pStage IA/IB	2	2
pStage IIA/IIB	2	3
pStage IIIA/IIIB	0	5
pStage IVA	3
Chemotherapy grade: 1a/2/3	7	4	1

Ut: Upper thoracic esophagus; Mt: Middle thoracic esophagus; Lt: Lower thoracic esophagus; EGJ: Esophagogastric junction; DCF: Docetaxel + cisplatin + 5-fluorouracil; FP: Cisplatin + 5-fluorouracil; 5-FU + CDGP: 5-fluorouracil + nedaplatin; Well: Well-differentiated squamous cell carcinoma; mod: Moderately differentiated squamous cell carcinoma; por: Poorly differentiated squamous cell carcinoma; tub2: Moderately differentiated tubular adenocarcinoma.

Table 2 Patient background characteristics and pathological findings for gastric cancer

Characteristic
Age: Minimum/maximum/median (years)	32	89	72
Sex: Men/women	11	4
Location: U/M/L	4	6	5
Operation: TG/DG/PG (laparoscopic operation)	5 (1)	10 (7)	0
Pathological histology of primary disease: Tub1/tub2/por1/por2/other	6	2	4	2	1
pT1/T2/T3/T4	2	3	5	5
pN0/N1/N2/N3a/N3b	5	2	4	2	2
pStage I: A/B	2	2
pStage II: A/B	1	2
pStage III: A/B/C	3	3	1
pStage IV	1

U: Upper part; M: Middle part; L: Lower part; TG: Total gastrectomy; DG: Distal gastrectomy; PG: Proximal gastrectomy; Tub1: Well-differentiated tubular adenocarcinoma; tub2: Moderately differentiated tubular adenocarcinoma; por1: Solid-type poorly differentiated adenocarcinoma; por2: Non-solid-type poorly differentiated adenocarcinoma.

Table 3 Shear-wave elastography measurement results

	Se	Sp	FN	FP	PPV	NPV
All	0.63	0.93	0.37	0.07	0.49	0.96
EC	0.69	0.92	0.31	0.08	0.28	0.99
GC	0.61	0.95	0.39	0.05	0.7	0.93

EC: Esophageal cancer; GC: Gastric cancer; Se: Sensitivity; Sp: Specificity; FN: False negative; FP: False positive; PPV: Positive predictive value; NPV: Negative predictive value.

Table 4 Shear-wave elastography measurement results for lymph nodes limited to larger than cut off value

	Se	Sp	FN	FP	PPV	NPV
All	0.76	0.82	0.23	0.18	0.53	0.94
EC	0.76	0.80	0.24	0.20	0.31	0.97
GC	0.78	0.86	0.22	0.14	0.74	0.89

EC: Esophageal cancer; GC: Gastric cancer; Se: Sensitivity; Sp: Specificity; FN: False negative; FP: False positive; PPV: Positive predictive value; NPV: Negative predictive value.