©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Apr 15, 2025; 17(4): 103128
Published online Apr 15, 2025. doi: 10.4251/wjgo.v17.i4.103128
Published online Apr 15, 2025. doi: 10.4251/wjgo.v17.i4.103128
Prognostic value of neutrophil-to-lymphocyte ratio in gastric cancer: Enhancing clinical relevance
Umashri Sundararaju, Hamrish Kumar Rajakumar, Department of General Surgery, Government Medical College, Omandurar Government Estate, Chennai 600002, Tamil Nādu, India
Author contributions: Sundararaju U contributed to the conceptualization, reviewing, and editing of the manuscript; Rajakumar HK contributed to the conceptualization of the manuscript and wrote the original draft; All authors have read and approved the final version of the manuscript.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Corresponding author: Hamrish Kumar Rajakumar, Department of General Surgery, Government Medical College, Omandurar Government Estate, Wallajah Road, Chennai 600002, Tamil Nādu, India. hamrishkumar2003@gmail.com
Received: November 11, 2024
Revised: January 10, 2025
Accepted: January 14, 2025
Published online: April 15, 2025
Processing time: 136 Days and 10.9 Hours
Revised: January 10, 2025
Accepted: January 14, 2025
Published online: April 15, 2025
Processing time: 136 Days and 10.9 Hours
Core Tip
Core Tip: The neutrophil-to-lymphocyte ratio (NLR) shows promise as a prognostic biomarker for gastric cancer, but its clinical use faces challenges, such as inconsistent cut-off values and unclear timing for measurement. Standardizing these factors, exploring additional inflammatory markers, and refining research methodologies will enhance NLR’s reliability and clinical utility in managing gastric cancer.