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Contents Volume 18 Issue 9 September 26, 2026

Editorial

Induced pluripotent stem cell-derived mesenchymal stem cell exosomes emerge as potent inducers of cancer cell senescence

Si-Feng Wang, Hai-Chun Guo, Xiao-Qin Gong, Xiang-Wen Peng

World J Stem Cells 18(9):115628. Published online Sep 26, 2026. doi: 10.4252/wjsc.115628

Abstract (60) | Core Tip (55) | Full Article (HTML) (235) | Full Article (PDF)-367K (46) | Full Article with Cover (PDF)-1947K (23) | Full Article (XML)-44K (26) | Audio-414K (0) | Received: 10/21/2025 | Revised: 11/25/2025 | Accepted: 01/26/2026 | RCA | CrossRef | Google Scholar | Similar Articles (68) | Cite | (32) | (27) | (0) | (0) | (0) | (818) | Open

Protocol defines product: Navigating function, safety and translation of induced pluripotent stem cell-derived mesenchymal stem cells

Chee-Yin Wong

World J Stem Cells 18(9):116437. Published online Sep 26, 2026. doi: 10.4252/wjsc.116437

Abstract (67) | Core Tip (62) | Full Article (HTML) (258) | Figures (1-1) (49) | Tables (1-1) (53) | Full Article (PDF)-502K (38) | Full Article with Cover (PDF)-2079K (32) | Full Article (XML)-74K (23) | Audio-279K (0) | Received: 11/11/2025 | Revised: 12/28/2025 | Accepted: 02/03/2026 | RCA | CrossRef | Google Scholar | Similar Articles (20) | Cite | (26) | (27) | (0) | (0) | (0) | (1435) | Open

Integration of stem cell therapy and artificial intelligence: From promise to clinical reality

Majid Ali, Mohammad Abdur Rahman, Khawaja Husnain Haider

World J Stem Cells 18(9):118676. Published online Sep 26, 2026. doi: 10.4252/wjsc.118676

Abstract (73) | Core Tip (58) | Full Article (HTML) (406) | Tables (1-1) (54) | Full Article (PDF)-484K (49) | Full Article with Cover (PDF)-2062K (37) | Full Article (XML)-125K (31) | Audio-2086K (0) | Received: 01/08/2026 | Revised: 01/30/2026 | Accepted: 03/05/2026 | RCA | CrossRef | Google Scholar | Similar Articles (418) | Cite | (41) | (42) | (0) | (0) | (0) | (31) | (1227) | (2) | Open

Review

Induced pluripotent stem cell-derived chimeric antigen receptor natural killer cells: Engineering innovations, translational hurdles and clinical prospects in immune therapy

Xu-Lin Liu, Si-Min Han, Gang-Hui Ye, Qing-Lu Wang, Ying Luo, Yan-Mei Liu

World J Stem Cells 18(9):122513. Published online Sep 26, 2026. doi: 10.4252/wjsc.122513

Abstract (92) | Core Tip (68) | Full Article (HTML) (304) | Figures (1-5) (50) | Tables (1-4) (60) | Full Article (PDF)-4781K (56) | Full Article with Cover (PDF)-6356K (38) | Full Article (XML)-439K (28) | Audio-1374K (0) | Received: 04/21/2026 | Revised: 06/30/2026 | Accepted: 08/28/2026 | RCA | CrossRef | Google Scholar | Similar Articles (0) | Cite | (34) | (42) | (0) | (0) | (0) | (1242) | Open

Minireviews

Cancer stem cell plasticity drives therapy resistance in colorectal cancer

Uğur Topal, Ahmet Gökhan Saritas, Cihan Zamur

World J Stem Cells 18(9):122395. Published online Sep 26, 2026. doi: 10.4252/wjsc.122395

Abstract (72) | Core Tip (57) | Full Article (HTML) (256) | Figures (1-3) (56) | Tables (1-2) (51) | Full Article (PDF)-6639K (47) | Full Article with Cover (PDF)-8218K (28) | Full Article (XML)-154K (28) | Audio-163K (0) | Received: 04/16/2026 | Revised: 07/10/2026 | Accepted: 09/15/2026 | RCA | CrossRef | Google Scholar | Similar Articles (1214) | Cite | (36) | (30) | (0) | (0) | (0) | (36) | (1819) | Open

Induced pluripotent stem cell-derived neuronal models in psychiatry: Mechanistic insights and translational horizons

Moria Maman, Orit Goldman, Talia Cohen Solal, Daphna Laifenfeld

World J Stem Cells 18(9):124169. Published online Sep 26, 2026. doi: 10.4252/wjsc.124169

Abstract (83) | Core Tip (56) | Full Article (HTML) (238) | Figures (1-1) (49) | Tables (1-2) (58) | Full Article (PDF)-1243K (40) | Full Article with Cover (PDF)-2823K (31) | Full Article (XML)-208K (18) | Audio-400K (0) | Received: 06/07/2026 | Revised: 07/13/2026 | Accepted: 08/26/2026 | RCA | CrossRef | Google Scholar | Similar Articles (0) | Cite | (26) | (31) | (0) | (0) | (0) | (29) | (1074) | Open

Lung organoids for preclinical evaluation of stem cell therapies: Opportunities, evidence, and translational challenges

Lu-Yu Yang, Yuan-Fang Xing, Jia-Yi Chen, Zhi-Min Cao, Huan Ye

World J Stem Cells 18(9):125409. Published online Sep 26, 2026. doi: 10.4252/wjsc.125409

Abstract (80) | Core Tip (60) | Full Article (HTML) (327) | Figures (1-3) (48) | Tables (1-4) (52) | Full Article (PDF)-4799K (54) | Full Article with Cover (PDF)-6378K (43) | Full Article (XML)-228K (33) | Audio-530K (0) | Received: 07/10/2026 | Revised: 08/15/2026 | Accepted: 09/22/2026 | RCA | CrossRef | Google Scholar | Similar Articles (0) | Cite | (38) | (38) | (0) | (0) | (0) | (1251) | Open

RNA-centered mechanisms sustaining self-renewal in hepatocellular carcinoma stem cells: Effector dosage, protein output and regulatory deployment

Yi Deng, Long Yan

World J Stem Cells 18(9):125599. Published online Sep 26, 2026. doi: 10.4252/wjsc.125599

Abstract (58) | Core Tip (60) | Full Article (HTML) (162) | Figures (1-4) (50) | Tables (1-1) (52) | Full Article (PDF)-2760K (45) | Full Article with Cover (PDF)-4343K (34) | Full Article (XML)-195K (24) | Audio-335K (0) | Received: 07/10/2026 | Revised: 08/12/2026 | Accepted: 09/11/2026 | RCA | CrossRef | Google Scholar | Similar Articles (1966) | Cite | (42) | (28) | (0) | (0) | (0) | (1491) | Open

Basic Study

Estrogen receptor 1 regulates ovarian cancer cell stemness and ferroptosis through modulation of the canonical RhoA/ROCK signaling pathway

Shun Zhou, Xue Cheng, Jing-Min Zhang, Jie Ji, Zhen-Zhen Ni, Wei Wang

World J Stem Cells 18(9):121744. Published online Sep 26, 2026. doi: 10.4252/wjsc.121744

Abstract (74) | Core Tip (66) | Full Article (HTML) (217) | Figures (1-6) (57) | Full Article (PDF)-8792K (30) | Full Article with Cover (PDF)-10370K (56) | Full Article (XML)-95K (19) | Audio-372K (0) | Received: 03/31/2026 | Revised: 05/19/2026 | Accepted: 08/28/2026 | RCA | CrossRef | Google Scholar | Similar Articles (98) | Cite | (29) | (30) | (0) | (0) | (0) | (28) | (1220) | Open

Carnitine palmitoyltransferase 1A facilitates the senescence of human dental pulp stem cells by Parkin succinylation-mediated mitophagy

Hai-Chi Lv, Yu-Feng Fan, Xue-Jun Ge

World J Stem Cells 18(9):122036. Published online Sep 26, 2026. doi: 10.4252/wjsc.122036

Abstract (76) | Core Tip (62) | Full Article (HTML) (201) | Figures (1-7) (49) | Full Article (PDF)-46019K (73) | Full Article with Cover (PDF)-47597K (30) | Full Article (XML)-126K (26) | Audio-356K (0) | Supplementary Material-677K (25) | Received: 04/07/2026 | Revised: 06/16/2026 | Accepted: 09/18/2026 | RCA | CrossRef | Google Scholar | Similar Articles (33) | Cite | (32) | (36) | (0) | (0) | (0) | (1763) | Open

Experimental study on ultrasound-targeted microbubble destruction promoting the proliferation, migration of human umbilical cord mesenchymal stem cells

Pan Zhang, Bo-Ya La, Man-Li Zhang, Burleshan Rewan, Ling-Yun Zhang, Xiao-Lin La

World J Stem Cells 18(9):123933. Published online Sep 26, 2026. doi: 10.4252/wjsc.123933

Abstract (66) | Core Tip (54) | Full Article (HTML) (240) | Figures (1-8) (49) | Tables (1-2) (49) | Full Article (PDF)-20403K (48) | Full Article with Cover (PDF)-21977K (21) | Full Article (XML)-142K (26) | Audio-2244K (0) | Received: 06/02/2026 | Revised: 07/12/2026 | Accepted: 09/16/2026 | RCA | CrossRef | Google Scholar | Similar Articles (45) | Cite | (35) | (28) | (0) | (0) | (0) | (37) | (1135) | Open

Density gradient centrifugation vs adherence for rat intestinal mesenchymal stem cell isolation

Su-Yu Lai, Yun Jiang, Run Yuan, Zhuo Wang, Yi-Chang Wang, Zi-Ting Zhao, Chao-Ying Cai, Meng-Yi Ruan, Yi-Xian Zeng, Bing Ren, Xiao-Feng Wang

World J Stem Cells 18(9):124197. Published online Sep 26, 2026. doi: 10.4252/wjsc.124197

Abstract (57) | Core Tip (60) | Full Article (HTML) (155) | Figures (1-9) (50) | Tables (1-2) (49) | Full Article (PDF)-31755K (67) | Full Article with Cover (PDF)-33333K (20) | Full Article (XML)-121K (20) | Audio-351K (0) | Received: 06/09/2026 | Revised: 07/24/2026 | Accepted: 09/15/2026 | RCA | CrossRef | Google Scholar | Similar Articles (35) | Cite | (34) | (29) | (0) | (0) | (0) | (1796) | Open

MED12 mutation activates Notch signaling to enhance cancer stemness and suppress CD8+ T cell cytotoxicity in lung cancer

Ying Yang, Jin-Long Zhong, Jia-Yuan Liu

World J Stem Cells 18(9):124540. Published online Sep 26, 2026. doi: 10.4252/wjsc.124540

Abstract (67) | Core Tip (61) | Full Article (HTML) (210) | Figures (1-8) (48) | Full Article (PDF)-6498K (29) | Full Article with Cover (PDF)-8075K (48) | Full Article (XML)-127K (21) | Audio-222K (0) | Supplementary Material-234K (15) | Received: 06/19/2026 | Revised: 07/18/2026 | Accepted: 09/18/2026 | RCA | CrossRef | Google Scholar | Similar Articles (103) | Cite | (25) | (26) | (0) | (0) | (0) | (27) | (1071) | Open

Meta-Analysis

Mesenchymal stem cell transplantation for severe acute pancreatitis-associated lung injury: A meta-analysis of animal studies

Guang-Xu Jing, Zhang-Peng Wang, Hong-Yu Sun, Yu Zhang, Guang-Qiang Gu

World J Stem Cells 18(9):124515. Published online Sep 26, 2026. doi: 10.4252/wjsc.124515

Abstract (71) | Core Tip (56) | Full Article (HTML) (164) | Figures (1-8) (47) | Tables (1-4) (49) | Full Article (PDF)-3594K (40) | Full Article with Cover (PDF)-5171K (26) | Full Article (XML)-127K (20) | Audio-1650K (0) | Received: 06/16/2026 | Revised: 07/18/2026 | Accepted: 09/23/2026 | RCA | CrossRef | Google Scholar | Similar Articles (771) | Cite | (25) | (28) | (0) | (0) | (0) | (26) | (1062) | Open

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