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Contents Volume 25 Issue 30 August 14, 2019

Editorial

Exhaled breath analysis in hepatology: State-of-the-art and perspectives

Antonio De Vincentis, Umberto Vespasiani-Gentilucci, Anna Sabatini, Raffaele Antonelli-Incalzi, Antonio Picardi

World J Gastroenterol 25(30):4043-4050. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4043

Abstract (1195) | Core Tip (1191) | Full Article (HTML) (7970) | Figures (1-1) (709) | Tables (1-2) (584) | Full Article (PDF)-3254K (750) | Audio-458K (60) | Peer-Review Report-191K (255) | Answering Reviewers-199K (450) | Received: 04/26/2019 | Revised: 06/11/2019 | Accepted: 06/26/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (22) | Total Visits (18148) | Similar Articles (0) | Timeline of Article Publication (3) | Authors Evaluation (8) | Article Quality Tracking (0) | Cite |

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Opinion Review

Miniature gastrointestinal endoscopy: Now and the future

John J McGoran, Mark E McAlindon, Prasad G Iyer, Eric J Seibel, Rehan Haidry, Laurence B Lovat, Sarmed S Sami

World J Gastroenterol 25(30):4051-4060. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4051

Abstract (1507) | Core Tip (1990) | Full Article (HTML) (8228) | Figures (1-5) (912) | Full Article (PDF)-15656K (767) | Audio-426K (20) | Peer-Review Report-167K (317) | Answering Reviewers-52K (316) | Received: 03/20/2019 | Revised: 06/22/2019 | Accepted: 07/03/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (17) | Total Visits (20204) | Similar Articles (0) | Timeline of Article Publication (1) | Authors Evaluation (3) | Article Quality Tracking (0) | Cite |

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Issues and controversies in esophageal inlet patch

Adriana Ciocalteu, Petrica Popa, Mircea Ionescu, Dan Ionut Gheonea

World J Gastroenterol 25(30):4061-4073. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4061

Abstract (1342) | Core Tip (1409) | Full Article (HTML) (13678) | Figures (1-5) (917) | Tables (1-1) (602) | Full Article (PDF)-17207K (1105) | Audio-881K (27) | Peer-Review Report-162K (312) | Answering Reviewers-59K (338) | Supplementary Material-84K (458) | Received: 03/10/2019 | Revised: 06/24/2019 | Accepted: 07/05/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (26) | Total Visits (26199) | Similar Articles (1) | Timeline of Article Publication (0) | Authors Evaluation (3) | Article Quality Tracking (0) | Cite |

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Review

Role of hepatocyte nuclear factor 4-alpha in gastrointestinal and liver diseases

Matthew M Yeh, Dustin E Bosch, Sayed S Daoud

World J Gastroenterol 25(30):4074-4091. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4074

Abstract (1207) | Core Tip (1244) | Full Article (HTML) (9275) | Figures (1-4) (671) | Tables (1-2) (651) | Full Article (PDF)-10758K (1299) | Audio-2031K (23) | Peer-Review Report-169K (379) | Answering Reviewers-59K (308) | Received: 03/25/2019 | Revised: 07/15/2019 | Accepted: 07/19/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (69) | Total Visits (19569) | Similar Articles (2) | Timeline of Article Publication (3) | Article Quality Tracking (0) | Cite |

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G protein-coupled estrogen receptor in colon function, immune regulation and carcinogenesis

Damian Jacenik, Ellen J Beswick, Wanda M Krajewska, Eric R Prossnitz

World J Gastroenterol 25(30):4092-4104. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4092

Abstract (1254) | Core Tip (1230) | Full Article (HTML) (9233) | Figures (1-1) (693) | Tables (1-2) (534) | Full Article (PDF)-1300K (1001) | Audio-774K (19) | Peer-Review Report-151K (359) | Answering Reviewers-133K (363) | Received: 03/27/2019 | Revised: 07/03/2019 | Accepted: 07/05/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (67) | Total Visits (20806) | Similar Articles (0) | Timeline of Article Publication (3) | Authors Evaluation (9) | Article Quality Tracking (0) | Cite |

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Helicobacter pylori and cytokine gene variants as predictors of premalignant gastric lesions

Anca Negovan, Mihaela Iancu, Emőke Fülöp, Claudia Bănescu

World J Gastroenterol 25(30):4105-4124. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4105

Abstract (1438) | Core Tip (1484) | Full Article (HTML) (6848) | Tables (1-2) (504) | Full Article (PDF)-803K (899) | Audio-1271K (47) | Peer-Review Report-222K (359) | Answering Reviewers-147K (343) | Received: 03/31/2019 | Revised: 07/12/2019 | Accepted: 07/19/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (38) | Total Visits (18307) | Similar Articles (2) | Timeline of Article Publication (3) | Article Quality Tracking (0) | Cite |

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Intestinal enteroids/organoids: A novel platform for drug discovery in inflammatory bowel diseases

Jun-Hwan Yoo, Mark Donowitz

World J Gastroenterol 25(30):4125-4147. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4125

Abstract (1763) | Core Tip (1412) | Full Article (HTML) (14223) | Figures (1-1) (600) | Tables (1-3) (622) | Full Article (PDF)-1325K (1920) | Audio-882K (40) | Peer-Review Report-227K (308) | Answering Reviewers-131K (461) | Received: 03/26/2019 | Revised: 06/14/2019 | Accepted: 07/19/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (70) | Total Visits (27283) | Similar Articles (50) | Timeline of Article Publication (3) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

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Minireviews

Colorectal cancer surveillance in inflammatory bowel disease: Practice guidelines and recent developments

William T Clarke, Joseph D Feuerstein

World J Gastroenterol 25(30):4148-4157. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4148

Abstract (1312) | Core Tip (1317) | Full Article (HTML) (18712) | Tables (1-1) (553) | Full Article (PDF)-700K (1969) | Audio-1695K (54) | Peer-Review Report-169K (334) | Answering Reviewers-156K (335) | Received: 05/03/2019 | Revised: 06/14/2019 | Accepted: 07/03/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (135) | Total Visits (30092) | Similar Articles (663) | Timeline of Article Publication (0) | Authors Evaluation (5) | Article Quality Tracking (1) | Cite |

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Elderly patients with inflammatory bowel disease: Updated review of the therapeutic landscape

Jean-Frédéric LeBlanc, Daniel Wiseman, Peter L Lakatos, Talat Bessissow

World J Gastroenterol 25(30):4158-4171. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4158

Abstract (1158) | Core Tip (1047) | Full Article (HTML) (6135) | Full Article (PDF)-909K (887) | Audio-1193K (29) | Peer-Review Report-177K (270) | Answering Reviewers-116K (675) | Received: 04/16/2019 | Revised: 06/27/2019 | Accepted: 07/03/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (39) | Total Visits (15559) | Similar Articles (784) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Reduced lysosomal acid lipase activity: A new marker of liver disease severity across the clinical continuum of non-alcoholic fatty liver disease?

Francesco Baratta, Daniele Pastori, Domenico Ferro, Giovanna Carluccio, Giulia Tozzi, Francesco Angelico, Francesco Violi, Maria Del Ben

World J Gastroenterol 25(30):4172-4180. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4172

Abstract (1549) | Core Tip (1152) | Full Article (HTML) (5525) | Figures (1-2) (797) | Tables (1-2) (506) | Full Article (PDF)-958K (969) | Audio-955K (25) | Peer-Review Report-174K (259) | Answering Reviewers-39K (271) | Received: 04/07/2019 | Revised: 06/20/2019 | Accepted: 07/03/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (30) | Total Visits (16480) | Similar Articles (229) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Beneficial effects of nutritional supplements on intestinal epithelial barrier functions in experimental colitis models in vivo

Hilda Vargas-Robles, Karla Fabiola Castro-Ochoa, Alí Francisco Citalán-Madrid, Michael Schnoor

World J Gastroenterol 25(30):4181-4198. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4181

Abstract (1439) | Core Tip (1369) | Full Article (HTML) (11916) | Figures (1-1) (550) | Tables (1-2) (608) | Full Article (PDF)-3353K (1140) | Audio-716K (44) | Peer-Review Report-161K (309) | Answering Reviewers-303K (321) | Received: 04/29/2019 | Revised: 06/12/2019 | Accepted: 07/05/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (48) | Total Visits (24421) | Similar Articles (83) | Timeline of Article Publication (3) | Authors Evaluation (7) | Article Quality Tracking (0) | Cite |

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Multiple “Omics” data-based biomarker screening for hepatocellular carcinoma diagnosis

Xiao-Na Liu, Dan-Ni Cui, Yu-Fang Li, Yun-He Liu, Gang Liu, Lei Liu

World J Gastroenterol 25(30):4199-4212. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4199

Abstract (1421) | Core Tip (1372) | Full Article (HTML) (12531) | Figures (1-1) (653) | Tables (1-2) (849) | Full Article (PDF)-1106K (1399) | Audio-882K (20) | Peer-Review Report-193K (370) | Answering Reviewers-242K (461) | Received: 04/08/2019 | Revised: 05/28/2019 | Accepted: 07/03/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (61) | Total Visits (25411) | Similar Articles (2159) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Basic Study

Novel magnetic compression technique for establishment of a canine model of tracheoesophageal fistula

Yi Gao, Rong-Qian Wu, Yi Lv, Xiao-Peng Yan

World J Gastroenterol 25(30):4213-4221. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4213

Abstract (1218) | Core Tip (1187) | Article Highlights (1257) | Full Article (HTML) (4896) | Figures (1-5) (696) | Full Article (PDF)-16962K (547) | Audio-203K (18) | Peer-Review Report-194K (286) | Answering Reviewers-70K (311) | Received: 04/06/2019 | Revised: 07/04/2019 | Accepted: 07/05/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (26) | Total Visits (17740) | Similar Articles (11) | Timeline of Article Publication (7) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

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Bone morphogenetic protein-7 represses hepatic stellate cell activation and liver fibrosis via regulation of TGF-β/Smad signaling pathway

Gao-Liang Zou, Shi Zuo, Shuang Lu, Rui-Han Hu, Yin-Ying Lu, Jing Yang, Kai-Sheng Deng, Ye-Ting Wu, Mao Mu, Juan-Juan Zhu, Jing-Zhang Zeng, Bao-Fang Zhang, Xian Wu, Xue-Ke Zhao, Hai-Yang Li

World J Gastroenterol 25(30):4222-4234. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4222

Abstract (1294) | Core Tip (1333) | Article Highlights (1245) | Full Article (HTML) (6659) | Figures (1-5) (1240) | Full Article (PDF)-9704K (857) | Audio-2427K (13) | Peer-Review Report-180K (318) | Answering Reviewers-80K (426) | Received: 04/15/2019 | Revised: 06/25/2019 | Accepted: 07/05/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (56) | Total Visits (21453) | Similar Articles (156) | Timeline of Article Publication (12) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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Retrospective Study

Natural history of children with mild Crohn’s disease

Yamini Sharma, Athos Bousvaros, Enju Liu, Julia Bender Stern

World J Gastroenterol 25(30):4235-4245. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4235

Abstract (1139) | Core Tip (1083) | Article Highlights (1245) | Full Article (HTML) (4631) | Figures (1-1) (537) | Tables (1-4) (514) | Full Article (PDF)-813K (825) | Audio-616K (19) | Peer-Review Report-180K (288) | Answering Reviewers-118K (291) | Received: 01/21/2019 | Revised: 07/03/2019 | Accepted: 07/05/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (13) | Total Visits (17818) | Similar Articles (203) | Timeline of Article Publication (8) | Article Quality Tracking (0) | Cite |

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Observational Study

Inflammatory bowel disease patient profiles are related to specific information needs: A nationwide survey

Saleh Daher, Tawfik Khoury, Ariel Benson, John R Walker, Oded Hammerman, Ron Kedem, Timna Naftali, Rami Eliakim, Ofer Ben-Bassat, Charles N Bernstein, Eran Israeli

World J Gastroenterol 25(30):4246-4260. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4246

Abstract (1423) | Core Tip (1120) | Article Highlights (1417) | Full Article (HTML) (4384) | Figures (1-1) (495) | Tables (1-5) (465) | Full Article (PDF)-1092K (661) | Audio-920K (41) | Peer-Review Report-182K (301) | Answering Reviewers-100K (292) | Supplementary Material-292K (259) | Received: 03/16/2019 | Revised: 06/09/2019 | Accepted: 06/23/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (29) | Total Visits (18916) | Similar Articles (0) | Timeline of Article Publication (5) | Authors Evaluation (2) | Article Quality Tracking (0) | Cite |

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Systematic Reviews

Frequency, localization, and types of gastrointestinal stromal tumor-associated neoplasia

Johanna Waidhauser, Anne Bornemann, Martin Trepel, Bruno Märkl

World J Gastroenterol 25(30):4261-4277. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4261

Abstract (1286) | Core Tip (1274) | Article Highlights (1374) | Full Article (HTML) (5676) | Figures (1-2) (522) | Tables (1-5) (705) | Full Article (PDF)-1522K (849) | Audio-396K (19) | Peer-Review Report-174K (368) | Answering Reviewers-87K (332) | Received: 04/18/2019 | Revised: 06/22/2019 | Accepted: 07/05/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (22) | Total Visits (20000) | Similar Articles (104) | Timeline of Article Publication (4) | Authors Evaluation (2) | Article Quality Tracking (0) | Cite |

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Meta-Analysis

Quantitative risk of positive family history in developing colorectal cancer: A meta-analysis

Parsa Mehraban Far, Abdulaziz Alshahrani, Mohammad Yaghoobi

World J Gastroenterol 25(30):4278-4291. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4278

Abstract (1330) | Core Tip (1244) | Article Highlights (1312) | Full Article (HTML) (5824) | Figures (1-4) (560) | Tables (1-1) (603) | Full Article (PDF)-2604K (592) | Audio-881K (16) | Peer-Review Report-175K (232) | Answering Reviewers-393K (396) | Supplementary Material-480K (282) | Received: 03/20/2019 | Revised: 07/06/2019 | Accepted: 07/19/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (19) | Total Visits (18411) | Similar Articles (1207) | Timeline of Article Publication (7) | Authors Evaluation (2) | Article Quality Tracking (0) | Cite |

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Letter to the Editor

Letter to the editor: Diagnosis of erythropoietic protoporphyria with severe liver injury - a case report

Debby Wensink, Margreet AEM Wagenmakers, JH Paul Wilson, Janneke G Langendonk

World J Gastroenterol 25(30):4292-4293. Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4292

Abstract (1216) | Core Tip (1198) | Full Article (HTML) (3747) | Full Article (PDF)-586K (607) | Audio-528K (16) | Peer-Review Report-172K (275) | Answering Reviewers-72K (387) | Received: 05/06/2019 | Revised: 07/17/2019 | Accepted: 07/19/2019 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (6) | Total Visits (12070) | Similar Articles (3) | Timeline of Article Publication (5) | Article Quality Tracking (0) | Cite |

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