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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 14, 2019; 25(30): 4213-4221
Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4213
Published online Aug 14, 2019. doi: 10.3748/wjg.v25.i30.4213
Novel magnetic compression technique for establishment of a canine model of tracheoesophageal fistula
Yi Gao, Yi Lv, Xiao-Peng Yan, Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, Shannxi Province, China
Yi Gao, Rong-Qian Wu, Yi Lv, Xiao-Peng Yan, National Local Joint Engineering Research Center for Precision Surgery and Regenerative Medicine, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, Shannxi Province, China
Author contributions: Yan XP and Lv Y designed the study; Gao Y and Yan XP performed the research and acquired the data; Gao Y and Yan XP analyzed the data; Yan XP, Gao Y, and Wu RQ drafted the manuscript; Gao Y, Wu RQ, Lv Y, and Yan XP contributed significantly to the revision of the manuscript.
Supported by the National Natural Science Foundation of China , No. 81700545 ; the Natural Science Basic Research Plan of Shaanxi Province of China , No. 2017JQ8021 ; and the Fundamental Research Funds for the Central Universities , No. xjj2018jchz14 .
Institutional review board statement: This study was approved by the Institutional Review Board of the First Affiliated Hospital of Xi’an Jiaotong University.
Institutional animal care and use committee statement: All procedures involving animals were reviewed and approved by the Institutional Animal Care and Use Committee of the First Affiliated Hospital of Xi’an Jiaotong University.
Conflict-of-interest statement: The authors declare no conflict of interests.
Data sharing statement: No additional data are available.
ARRIVE guidelines statement: The ARRIVE Guidelines have been adopted.
Open-Access: This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Xiao-Peng Yan, PhD, Doctor, Surgeon, Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, No. 277, West Yanta Road, Xi’an 710061, Shannxi Province, China. yanxiaopeng99@163.com
Telephone: +86-29-82657541
Received: April 8, 2019
Peer-review started: April 8, 2019
First decision: May 30, 2019
Revised: July 4, 2019
Accepted: July 5, 2019
Article in press: July 5, 2019
Published online: August 14, 2019
Processing time: 129 Days and 22.9 Hours
Peer-review started: April 8, 2019
First decision: May 30, 2019
Revised: July 4, 2019
Accepted: July 5, 2019
Article in press: July 5, 2019
Published online: August 14, 2019
Processing time: 129 Days and 22.9 Hours
Core Tip
Core tip: The magnetic compression technique (MCT) is usually used clinically for anastomosis. We propose a novel application for the MCT in establishing a canine model of tracheoesophageal fistula (TEF). This is the first study to apply the MCT in the development of a disease model. Findings showed that it is simple, feasible, and minimally invasive to use magnetic compression technique for the establishment of the TEF model in dogs. It can be used to study the pathophysiological changes of TEF and to provide a good and stable model for exploring the advantages and disadvantages of various surgical methods.