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Contents Volume 27 Issue 39 October 21, 2021

Editorial

Importance of BRCA mutation for the current treatment of pancreatic cancer beyond maintenance

Joaquina Martínez-Galán, Isabel Rodriguez, Octavio Caba

World J Gastroenterol 27(39):6515-6521. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6515

Abstract (1015) | Core Tip (943) | Full Article (HTML) (3723) | Tables (1-1) (454) | Full Article (PDF)-5808K (476) | Audio-844K (32) | Peer-Review Report-217K (183) | Answering Reviewers-247K (207) | Received: 03/16/2021 | Revised: 05/10/2021 | Accepted: 09/03/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (12819) | Similar Articles (794) | Timeline of Article Publication (5) | Authors Evaluation (2) | Article Quality Tracking (1) | Reader Comments (1) | Cite |

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Frontier

Acetyl-CoA carboxylase inhibitors in non-alcoholic steatohepatitis: Is there a benefit?

Georgios Neokosmidis, Evangelos Cholongitas, Konstantinos Tziomalos

World J Gastroenterol 27(39):6522-6526. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6522

Abstract (868) | Core Tip (1183) | Full Article (HTML) (3481) | Tables (1-1) (586) | Full Article (PDF)-5778K (362) | Audio-110K (11) | Peer-Review Report-209K (193) | Answering Reviewers-39K (182) | Received: 03/28/2021 | Revised: 06/28/2021 | Accepted: 09/23/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (10) | Total Visits (10362) | Similar Articles (48) | Timeline of Article Publication (2) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Review

Therapeutic resistance in pancreatic ductal adenocarcinoma: Current challenges and future opportunities

Aditi Jain, Vikas Bhardwaj

World J Gastroenterol 27(39):6527-6550. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6527

Abstract (1655) | Core Tip (1417) | Full Article (HTML) (6068) | Tables (1-3) (1051) | Full Article (PDF)-5969K (633) | Audio-910K (44) | Peer-Review Report-216K (220) | Answering Reviewers-369K (194) | Received: 05/06/2021 | Revised: 06/22/2021 | Accepted: 08/30/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (51) | Total Visits (14385) | Similar Articles (451) | Timeline of Article Publication (0) | Authors Evaluation (6) | Article Quality Tracking (1) | Reader Comments (1) | Cite |

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Evaluation of botanicals as potential COVID-19 symptoms terminator

Ufuk Koca Caliskan, Methiye Mancak Karakus

World J Gastroenterol 27(39):6551-6571. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6551

Abstract (1775) | Core Tip (993) | Full Article (HTML) (5400) | Tables (1-4) (1448) | Full Article (PDF)-5934K (548) | Audio-1096K (45) | Peer-Review Report-209K (239) | Answering Reviewers-51K (230) | Received: 03/16/2021 | Revised: 05/01/2021 | Accepted: 09/16/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (6) | Total Visits (15139) | Similar Articles (725) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Minireviews

Current and emerging therapeutic strategies in pancreatic cancer: Challenges and opportunities

Manish Manrai, T V S V G K Tilak, Saurabh Dawra, Sharad Srivastava, Anupam Singh

World J Gastroenterol 27(39):6572-6589. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6572

Abstract (1062) | Core Tip (960) | Full Article (HTML) (5235) | Figures (1-4) (577) | Tables (1-2) (641) | Full Article (PDF)-6128K (769) | Audio-594K (15) | Peer-Review Report-200K (271) | Answering Reviewers-54K (268) | Received: 01/28/2021 | Revised: 05/09/2021 | Accepted: 08/16/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (26) | Total Visits (14005) | Similar Articles (36) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Reader Comments (1) | Cite |

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Cathepsin L, transmembrane peptidase/serine subfamily member 2/4, and other host proteases in COVID-19 pathogenesis – with impact on gastrointestinal tract

Izabela Berdowska, Malgorzata Matusiewicz

World J Gastroenterol 27(39):6590-6600. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6590

Abstract (1409) | Core Tip (922) | Full Article (HTML) (4732) | Figures (1-2) (606) | Tables (1-1) (548) | Full Article (PDF)-6876K (589) | Audio-1366K (12) | Peer-Review Report-205K (221) | Answering Reviewers-93K (208) | Received: 03/29/2021 | Revised: 06/28/2021 | Accepted: 09/19/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (17) | Total Visits (14224) | Similar Articles (761) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Endoscopic anti-reflux therapy for gastroesophageal reflux disease

Enrique Rodríguez de Santiago, Eduardo Albéniz, Fermin Estremera-Arevalo, Carlos Teruel Sanchez-Vegazo, Vicente Lorenzo-Zúñiga

World J Gastroenterol 27(39):6601-6614. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6601

Abstract (1008) | Core Tip (826) | Full Article (HTML) (8475) | Tables (1-3) (907) | Full Article (PDF)-5877K (877) | Audio-564K (49) | Peer-Review Report-198K (274) | Answering Reviewers-443K (230) | Received: 04/19/2021 | Revised: 07/01/2021 | Accepted: 08/31/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (39) | Total Visits (16536) | Similar Articles (41) | Timeline of Article Publication (2) | Authors Evaluation (4) | Article Quality Tracking (0) | Reader Comments (1) | Cite |

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Basic Study

Cold exposure and capsaicin promote 1,2-dimethylhyrazine-induced colon carcinogenesis in rats correlates with extracellular matrix remodeling

Jing-Chun Qin, Wei-Tao Yu, Hui-Xuan Li, Yu-Qi Liang, Fei-Fei Nong, Bin Wen

World J Gastroenterol 27(39):6615-6630. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6615

Abstract (1638) | Core Tip (1544) | Article Highlights (1021) | Full Article (HTML) (3600) | Figures (1-8) (633) | Tables (1-1) (998) | Full Article (PDF)-55783K (514) | Audio-849K (4) | Peer-Review Report-200K (216) | Answering Reviewers-115K (219) | Received: 04/13/2021 | Revised: 07/02/2021 | Accepted: 07/30/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (10) | Total Visits (16052) | Similar Articles (5) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Detection and analysis of common pathogenic germline mutations in Peutz-Jeghers syndrome

Guo-Li Gu, Zhi Zhang, Yu-Hui Zhang, Peng-Fei Yu, Zhi-Wei Dong, Hai-Rui Yang, Ying Yuan

World J Gastroenterol 27(39):6631-6646. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6631

Abstract (807) | Core Tip (844) | Article Highlights (882) | Full Article (HTML) (4114) | Tables (1-10) (621) | Full Article (PDF)-5876K (402) | Audio-2193K (2) | Peer-Review Report-244K (177) | Answering Reviewers-53K (193) | Received: 04/15/2021 | Revised: 05/31/2021 | Accepted: 08/11/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (11) | Total Visits (11908) | Similar Articles (62) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Clinical and Translational Research

Validation of the Italian translation of the perceived stigma scale and resilience assessment in inflammatory bowel disease patients

Sara Cococcia, Marco Vincenzo Lenti, Caterina Mengoli, Catherine Klersy, Federica Borrelli de Andreis, Matteo Secco, Jihane Ghorayeb, Mariangela Delliponti, Gino Roberto Corazza, Antonio Di Sabatino

World J Gastroenterol 27(39):6647-6658. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6647

Abstract (784) | Core Tip (1398) | Article Highlights (873) | Full Article (HTML) (3354) | Tables (1-4) (480) | Full Article (PDF)-5853K (408) | Audio-3801K (13) | Peer-Review Report-124K (159) | Answering Reviewers-110K (187) | Supplementary Material-67K (186) | Received: 02/14/2021 | Revised: 03/21/2021 | Accepted: 10/11/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (13) | Total Visits (12866) | Similar Articles (155) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (0) | Cite |

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Retrospective Cohort Study

Prognostic factors of minimally invasive surgery for gastric cancer: Does robotic gastrectomy bring oncological benefit?

Masaya Nakauchi, Koichi Suda, Susumu Shibasaki, Kenichi Nakamura, Shinichi Kadoya, Kenji Kikuchi, Kazuki Inaba, Ichiro Uyama

World J Gastroenterol 27(39):6659-6672. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6659

Abstract (933) | Core Tip (830) | Article Highlights (1024) | Full Article (HTML) (4291) | Figures (1-3) (531) | Tables (1-5) (515) | Full Article (PDF)-6589K (520) | Audio-993K (8) | Peer-Review Report-166K (209) | Answering Reviewers-131K (207) | Received: 04/26/2021 | Revised: 06/18/2021 | Accepted: 09/23/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (35) | Total Visits (13634) | Similar Articles (1307) | Timeline of Article Publication (2) | Authors Evaluation (2) | Article Quality Tracking (0) | Cite |

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Observational Study

Diagnostic usefulness of selected proteases and acute phase factors in patients with colorectal adenocarcinoma

Tadeusz Sebzda, Jan Gnus, Barbara Dziadkowiec, Miroslaw Latka, Jakub Gburek

World J Gastroenterol 27(39):6673-6688. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6673

Abstract (1527) | Core Tip (883) | Article Highlights (911) | Full Article (HTML) (2720) | Figures (1-1) (515) | Tables (1-5) (485) | Full Article (PDF)-6361K (346) | Audio-1867K (9) | Peer-Review Report-196K (196) | Answering Reviewers-204K (176) | Received: 04/07/2021 | Revised: 07/07/2021 | Accepted: 09/02/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (4) | Total Visits (12392) | Similar Articles (0) | Timeline of Article Publication (2) | Authors Evaluation (2) | Article Quality Tracking (0) | Cite |

(1) | (0) | (0) | (0) | Open

Impact of a colorectal cancer screening program implantation on delays and prognosis of non-screening detected colorectal cancer

Joaquin Cubiella, María Lorenzo, Franco Baiocchi, Coral Tejido, Alejandro Conde, María Sande-Meijide, Margarita Castro

World J Gastroenterol 27(39):6689-6700. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6689

Abstract (1003) | Core Tip (913) | Article Highlights (1042) | Full Article (HTML) (3219) | Figures (1-4) (457) | Tables (1-3) (415) | Full Article (PDF)-6420K (483) | Audio-592K (14) | Peer-Review Report-213K (211) | Answering Reviewers-114K (213) | Received: 04/14/2021 | Revised: 07/15/2021 | Accepted: 09/08/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (7) | Total Visits (12562) | Similar Articles (1417) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | Cite |

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Prospective Study

Standard liver weight model in adult deceased donors with fatty liver: A prospective cohort study

Bo Li, Pan-Yu Chen, Yi-Fei Tan, He Huang, Min Jiang, Zhen-Ru Wu, Chen-Hao Jiang, Dao-Feng Zheng, Diao He, Yu-Jun Shi, Yan Luo, Jia-Yin Yang

World J Gastroenterol 27(39):6701-6714. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6701

Abstract (1000) | Core Tip (972) | Article Highlights (961) | Full Article (HTML) (3503) | Figures (1-3) (628) | Tables (1-5) (600) | Full Article (PDF)-7981K (462) | Audio-1813K (23) | Peer-Review Report-198K (190) | Answering Reviewers-84K (191) | Supplementary Material-60K (192) | Received: 06/20/2021 | Revised: 08/22/2021 | Accepted: 09/16/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (12829) | Similar Articles (84) | Timeline of Article Publication (0) | Authors Evaluation (3) | Article Quality Tracking (0) | Cite |

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Systematic Reviews

Microbiota shaping — the effects of probiotics, prebiotics, and fecal microbiota transplant on cognitive functions: A systematic review

Simone Baldi, Tiziana Mundula, Giulia Nannini, Amedeo Amedei

World J Gastroenterol 27(39):6715-6732. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6715

Abstract (1225) | Core Tip (1541) | Article Highlights (1050) | Full Article (HTML) (10127) | Figures (1-2) (1104) | Tables (1-1) (557) | Full Article (PDF)-6764K (822) | Audio-740K (24) | Peer-Review Report-263K (255) | Answering Reviewers-567K (246) | Supplementary Material-439K (232) | Received: 02/25/2021 | Revised: 05/12/2021 | Accepted: 09/02/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (72) | Total Visits (22199) | Similar Articles (61) | Timeline of Article Publication (0) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

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Letter to the Editor

Impact of COVID-19 pandemic on the neuropsychiatric status of Wilson’s disease

Giuseppe Lanza, Massimiliano Godani, Raffaele Ferri, Alberto Raggi

World J Gastroenterol 27(39):6733-6736. Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6733

Abstract (893) | Core Tip (1223) | Full Article (HTML) (2890) | Full Article (PDF)-5765K (377) | Audio-630K (19) | Peer-Review Report-218K (187) | Answering Reviewers-99K (224) | Received: 07/17/2021 | Revised: 08/11/2021 | Accepted: 09/23/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (12) | Total Visits (10702) | Similar Articles (728) | Timeline of Article Publication (1) | Authors Evaluation (3) | Article Quality Tracking (0) | Cite |

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