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Contents Volume 22 Issue 8 February 28, 2016

Topic Highlight

Advanced gastric cancer: Current treatment landscape and future perspectives

Antonia Digklia, Anna Dorothea Wagner

World J Gastroenterol 22(8):2403-2414. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2403

Abstract (1968) | Core Tip (1721) | Full Article (HTML) (22815) | Tables (1-1) (542) | Full Article (PDF)-1046K (2265) | Audio-663K (45) | Peer-Review Report-103K (344) | Answering Reviewers-77K (372) | Received: 04/30/2015 | Revised: 09/10/2015 | Accepted: 11/24/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (439) | Total Visits (38394) | Similar Articles (1290) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Fibroblast growth factor receptor signaling as therapeutic targets in gastric cancer

Masakazu Yashiro, Tasuku Matsuoka

World J Gastroenterol 22(8):2415-2423. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2415

Abstract (1491) | Core Tip (1441) | Full Article (HTML) (9305) | Figures (1-2) (956) | Tables (1-2) (517) | Full Article (PDF)-1072K (1143) | Audio-1028K (24) | Peer-Review Report-91K (349) | Answering Reviewers-273K (446) | Received: 04/27/2015 | Revised: 05/25/2015 | Accepted: 12/08/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (34) | Total Visits (23221) | Similar Articles (1283) | Timeline of Article Publication (4) | Article Quality Tracking (0) | Cite |

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Current status in remnant gastric cancer after distal gastrectomy

Masaichi Ohira, Takahiro Toyokawa, Katsunobu Sakurai, Naoshi Kubo, Hiroaki Tanaka, Kazuya Muguruma, Masakazu Yashiro, Naoyoshi Onoda, Kosei Hirakawa

World J Gastroenterol 22(8):2424-2433. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2424

Abstract (2105) | Core Tip (1741) | Full Article (HTML) (7352) | Tables (1-6) (683) | Full Article (PDF)-953K (1164) | Audio-1070K (27) | Peer-Review Report-68K (372) | Answering Reviewers-17K (412) | Received: 04/28/2015 | Accepted: 12/14/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (82) | Total Visits (23194) | Similar Articles (6) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Emerging molecular basis of hematogenous metastasis in gastric cancer

Jing Zhong, Yan Chen, Liang-Jing Wang

World J Gastroenterol 22(8):2434-2440. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2434

Abstract (1512) | Core Tip (1711) | Full Article (HTML) (7142) | Tables (1-1) (567) | Full Article (PDF)-931K (1008) | Audio-1653K (30) | Peer-Review Report-85K (340) | Answering Reviewers-54K (381) | Received: 04/28/2015 | Revised: 10/29/2015 | Accepted: 11/19/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (34) | Total Visits (19051) | Similar Articles (1413) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Review

Peroxisome proliferator activated receptors at the crossroad of obesity, diabetes, and pancreatic cancer

Simone Polvani, Mirko Tarocchi, Sara Tempesti, Lapo Bencini, Andrea Galli

World J Gastroenterol 22(8):2441-2459. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2441

Abstract (1989) | Core Tip (1553) | Full Article (HTML) (10384) | Figures (1-1) (666) | Full Article (PDF)-1377K (1486) | Audio-591K (46) | Peer-Review Report-77K (373) | Answering Reviewers-92K (340) | Received: 09/28/2015 | Revised: 12/17/2015 | Accepted: 01/11/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (74) | Total Visits (26855) | Similar Articles (445) | Timeline of Article Publication (7) | Article Quality Tracking (0) | Cite |

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Molecular alterations in gastric cancer with special reference to the early-onset subtype

Małgorzata Skierucha, Anya NA Milne, G Johan A Offerhaus, Wojciech P Polkowski, Ryszard Maciejewski, Robert Sitarz

World J Gastroenterol 22(8):2460-2474. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2460

Abstract (1783) | Core Tip (1558) | Full Article (HTML) (7576) | Figures (1-1) (625) | Tables (1-3) (526) | Full Article (PDF)-1135K (1223) | Audio-920K (22) | Peer-Review Report-120K (353) | Answering Reviewers-296K (442) | Received: 09/22/2015 | Revised: 11/06/2015 | Accepted: 12/30/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (49) | Total Visits (21623) | Similar Articles (1284) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Estrogen receptors in gastric cancer: Advances and perspectives

Muhammad Saif Ur Rahman, Jiang Cao

World J Gastroenterol 22(8):2475-2482. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2475

Abstract (1787) | Core Tip (1620) | Full Article (HTML) (7429) | Figures (1-2) (544) | Tables (1-1) (541) | Full Article (PDF)-1125K (1046) | Audio-2320K (43) | Peer-Review Report-92K (306) | Answering Reviewers-83K (281) | Received: 09/30/2015 | Revised: 11/23/2015 | Accepted: 12/14/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (71) | Total Visits (22124) | Similar Articles (1285) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Glycosyltransferases and non-alcoholic fatty liver disease

Yu-Tao Zhan, Hai-Ying Su, Wei An

World J Gastroenterol 22(8):2483-2493. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2483

Abstract (1709) | Core Tip (1542) | Full Article (HTML) (7305) | Figures (1-2) (367) | Full Article (PDF)-1426K (981) | Audio-472K (23) | Peer-Review Report-113K (333) | Answering Reviewers-75K (342) | Received: 05/11/2015 | Revised: 10/22/2015 | Accepted: 11/19/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (24) | Total Visits (18229) | Similar Articles (227) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Minireviews

Hepatocellular carcinoma and non-alcoholic steatohepatitis: The state of play

Bérénice Charrez, Liang Qiao, Lionel Hebbard

World J Gastroenterol 22(8):2494-2502. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2494

Abstract (1563) | Core Tip (1430) | Full Article (HTML) (7768) | Full Article (PDF)-945K (1292) | Audio-2729K (32) | Peer-Review Report-113K (311) | Answering Reviewers-163K (290) | Received: 11/02/2015 | Revised: 12/18/2015 | Accepted: 12/30/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (42) | Total Visits (18488) | Similar Articles (1921) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Basic Study

Sphingosine kinase 1 is upregulated with lysophosphatidic acid receptor 2 in human colorectal cancer

Dai Shida, Satoru Inoue, Yuki Yoshida, Atsushi Kodaka, Tsutomu Tsuji, Makoto Tsuiji

World J Gastroenterol 22(8):2503-2511. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2503

Abstract (1489) | Core Tip (1504) | Full Article (HTML) (4902) | Figures (1-3) (546) | Tables (1-2) (540) | Full Article (PDF)-1073K (639) | Audio-201K (30) | Peer-Review Report-95K (326) | Answering Reviewers-45K (317) | Received: 10/11/2015 | Revised: 11/22/2015 | Accepted: 12/14/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (16) | Total Visits (16414) | Similar Articles (1143) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Glucagon-like peptide-1 analogue prevents nonalcoholic steatohepatitis in non-obese mice

Takaya Yamamoto, Yukiomi Nakade, Taeko Yamauchi, Yuji Kobayashi, Norimitsu Ishii, Tomohiko Ohashi, Kiyoaki Ito, Ken Sato, Yoshitaka Fukuzawa, Masashi Yoneda

World J Gastroenterol 22(8):2512-2523. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2512

Abstract (2187) | Core Tip (1500) | Full Article (HTML) (6784) | Figures (1-5) (645) | Tables (1-2) (573) | Full Article (PDF)-1830K (894) | Audio-1150K (37) | Peer-Review Report-93K (427) | Answering Reviewers-171K (316) | Received: 10/26/2015 | Revised: 12/08/2015 | Accepted: 12/21/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (41) | Total Visits (21753) | Similar Articles (49) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Relationship of serum polyunsaturated fatty acids with cytokines in colorectal cancer

He-Jin Jia, Peng-Jun Zhang, Yu-Lan Liu, Chao-Guang Jiang, Xu Zhu, Ya-Ping Tian

World J Gastroenterol 22(8):2524-2532. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2524

Abstract (1389) | Core Tip (1300) | Full Article (HTML) (5660) | Figures (1-3) (552) | Tables (1-3) (510) | Full Article (PDF)-1150K (720) | Audio-1524K (17) | Peer-Review Report-91K (412) | Answering Reviewers-8K (358) | Received: 01/11/2016 | Revised: 02/03/2016 | Accepted: 02/19/2016 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (7) | Total Visits (19529) | Similar Articles (1159) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Dietary saturated fatty acid and polyunsaturated fatty acid oppositely affect hepatic NOD-like receptor protein 3 inflammasome through regulating nuclear factor-kappa B activation

Yong-Heng Sui, Wen-Jing Luo, Qin-Yu Xu, Jing Hua

World J Gastroenterol 22(8):2533-2544. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2533

Abstract (1683) | Core Tip (1466) | Full Article (HTML) (6539) | Figures (1-5) (673) | Full Article (PDF)-1918K (903) | Audio-498K (64) | Peer-Review Report-87K (377) | Answering Reviewers-25K (364) | Received: 06/28/2015 | Revised: 10/17/2015 | Accepted: 12/30/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (53) | Total Visits (20102) | Similar Articles (3) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Role of CD56-expressing immature biliary epithelial cells in biliary atresia

Rui-Zhong Zhang, Jia-Kang Yu, Jiao Peng, Feng-Hua Wang, Hai-Ying Liu, Vincent CH Lui, John M Nicholls, Paul KH Tam, Jonathan R Lamb, Yan Chen, Hui-Min Xia

World J Gastroenterol 22(8):2545-2557. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2545

Abstract (1506) | Core Tip (1421) | Full Article (HTML) (8248) | Figures (1-5) (668) | Tables (1-3) (601) | Full Article (PDF)-2971K (912) | Audio-705K (45) | Peer-Review Report-87K (382) | Answering Reviewers-83K (449) | Received: 07/29/2015 | Revised: 11/04/2015 | Accepted: 12/21/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (13) | Total Visits (23360) | Similar Articles (30) | Timeline of Article Publication (3) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

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Improved prescription of taohechengqi-tang alleviates D-galactosamine acute liver failure in rats

Yang Zhang, Jian-Xing Luo, Xiao-Yu Hu, Fang Yang, Sen Zhong, Wu Lin

World J Gastroenterol 22(8):2558-2565. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2558

Abstract (1380) | Core Tip (1353) | Full Article (HTML) (4530) | Figures (1-2) (548) | Tables (1-3) (534) | Full Article (PDF)-1528K (624) | Audio-1240K (26) | Peer-Review Report-80K (349) | Answering Reviewers-98K (370) | Received: 07/08/2015 | Revised: 10/13/2015 | Accepted: 11/24/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (12) | Total Visits (18395) | Similar Articles (78) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Moxibustion regulates inflammatory mediators and colonic mucosal barrier in ulcerative colitis rats

Tie-Ming Ma, Na Xu, Xian-De Ma, Zeng-Hua Bai, Xing Tao, Hong-Chi Yan

World J Gastroenterol 22(8):2566-2575. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2566

Abstract (1877) | Core Tip (1563) | Full Article (HTML) (6003) | Figures (1-5) (576) | Tables (1-1) (504) | Full Article (PDF)-1745K (806) | Audio-1585K (27) | Peer-Review Report-96K (404) | Answering Reviewers-34K (431) | Received: 09/13/2015 | Revised: 10/30/2015 | Accepted: 12/01/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (26) | Total Visits (21148) | Similar Articles (411) | Timeline of Article Publication (3) | Article Quality Tracking (0) | Cite |

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Case Control Study

Significance and prognostic value of increased serum direct bilirubin level for lymph node metastasis in Chinese rectal cancer patients

Chun Gao, Long Fang, Jing-Tao Li, Hong-Chuan Zhao

World J Gastroenterol 22(8):2576-2584. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2576

Abstract (1521) | Core Tip (1389) | Full Article (HTML) (4725) | Figures (1-3) (541) | Tables (1-5) (523) | Full Article (PDF)-1136K (690) | Audio-428K (25) | Peer-Review Report-83K (351) | Answering Reviewers-88K (323) | Received: 08/10/2015 | Revised: 10/25/2015 | Accepted: 12/08/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (28) | Total Visits (18445) | Similar Articles (297) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Retrospective Cohort Study

Risk factors for tuberculosis after gastrectomy in gastric cancer

Won Jai Jung, Young Mok Park, Joo Han Song, Kyung Soo Chung, Song Yee Kim, Eun Young Kim, Ji Ye Jung, Moo Suk Park, Young Sam Kim, Se Kyu Kim, Joon Chang, Sung Hoon Noh, Ji Yeong An, Young Ae Kang

World J Gastroenterol 22(8):2585-2591. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2585

Abstract (1719) | Core Tip (1333) | Full Article (HTML) (4092) | Tables (1-4) (538) | Full Article (PDF)-1026K (632) | Audio-394K (10) | Peer-Review Report-113K (324) | Answering Reviewers-131K (278) | Received: 07/02/2015 | Revised: 09/18/2015 | Accepted: 12/01/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (11) | Total Visits (17703) | Similar Articles (1487) | Timeline of Article Publication (1) | Article Quality Tracking (0) | Cite |

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Helicobacter pylori infection is not associated with nonalcoholic fatty liver disease

Myong Ki Baeg, Seung Kew Yoon, Sun-Hye Ko, Yong-Sun Noh, In-Seok Lee, Myung-Gyu Choi

World J Gastroenterol 22(8):2592-2600. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2592

Abstract (1677) | Core Tip (1459) | Full Article (HTML) (6227) | Figures (1-1) (516) | Tables (1-4) (514) | Full Article (PDF)-1069K (1383) | Audio-1128K (19) | Peer-Review Report-130K (309) | Answering Reviewers-146K (324) | Received: 10/03/2015 | Revised: 11/22/2015 | Accepted: 12/14/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (63) | Total Visits (20543) | Similar Articles (200) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Prognostic factors and long-term outcomes of hilar cholangiocarcinoma: A single-institution experience in China

Hai-Jie Hu, Hui Mao, Anuj Shrestha, Yong-Qiong Tan, Wen-Jie Ma, Qin Yang, Jun-Ke Wang, Nan-Sheng Cheng, Fu-Yu Li

World J Gastroenterol 22(8):2601-2610. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2601

Abstract (1788) | Core Tip (1478) | Full Article (HTML) (7162) | Figures (1-3) (575) | Tables (1-3) (502) | Full Article (PDF)-1096K (683) | Audio-441K (11) | Peer-Review Report-157K (321) | Answering Reviewers-390K (348) | Received: 10/13/2015 | Revised: 11/18/2015 | Accepted: 12/08/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (59) | Total Visits (19848) | Similar Articles (35) | Timeline of Article Publication (0) | Article Quality Tracking (0) | Cite |

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Retrospective Study

Outcomes and patients’ perspectives of transition from paediatric to adult care in inflammatory bowel disease

Alice L Bennett, David Moore, Peter A Bampton, Robert V Bryant, Jane M Andrews

World J Gastroenterol 22(8):2611-2620. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2611

Abstract (1500) | Core Tip (1340) | Full Article (HTML) (5520) | Figures (1-1) (546) | Tables (1-4) (469) | Full Article (PDF)-1137K (702) | Audio-2320K (29) | Peer-Review Report-97K (317) | Answering Reviewers-304K (303) | Received: 09/28/2015 | Revised: 11/30/2015 | Accepted: 12/14/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (37) | Total Visits (17150) | Similar Articles (663) | Timeline of Article Publication (4) | Article Quality Tracking (0) | Cite |

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Feasibility of full-spectrum endoscopy: Korea’s first full-spectrum endoscopy colonoscopic trial

Jeong-Yeop Song, Youn Hee Cho, Mi A Kim, Jeong-Ae Kim, Chun Tek Lee, Moon Sung Lee

World J Gastroenterol 22(8):2621-2629. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2621

Abstract (1546) | Core Tip (1546) | Full Article (HTML) (5177) | Figures (1-2) (530) | Tables (1-2) (538) | Full Article (PDF)-1350K (769) | Audio-1237K (27) | Peer-Review Report-154K (312) | Answering Reviewers-182K (329) | Received: 09/17/2015 | Revised: 10/20/2015 | Accepted: 11/19/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (8) | Total Visits (18941) | Similar Articles (226) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Case Report

Ombitasvir, paritaprevir, ritonavir, dasabuvir and ribavirin in cirrhosis after complete destruction of hepatocellular carcinoma

Zahariy Krastev, Deian Jelev, Krasimir Antonov, Tanya Petkova, Evelina Atanasova, Nadezhda Zheleva, Bojidar Tomov, Yana Boyanova, Lyudmila Mateva

World J Gastroenterol 22(8):2630-2635. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2630

Abstract (1834) | Core Tip (1396) | Full Article (HTML) (3435) | Tables (1-4) (498) | Full Article (PDF)-882K (596) | Audio-955K (26) | Peer-Review Report-76K (258) | Answering Reviewers-60K (300) | Received: 08/26/2015 | Revised: 10/21/2015 | Accepted: 12/16/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (5) | Total Visits (15521) | Similar Articles (1925) | Timeline of Article Publication (5) | Article Quality Tracking (0) | Cite |

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Condyloma acuminatum of the anal canal, treated with endoscopic submucosal dissection

Akiko Sasaki, Takeshi Nakajima, Hideto Egashira, Kotaro Takeda, Shinnosuke Tokoro, Chikamasa Ichita, Sakue Masuda, Haruki Uojima, Kazuya Koizumi, Takeshi Kinbara, Taku Sakamoto, Yutaka Saito, Makoto Kako

World J Gastroenterol 22(8):2636-2641. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2636

Abstract (1708) | Core Tip (1585) | Full Article (HTML) (14640) | Figures (1-3) (962) | Tables (1-1) (577) | Full Article (PDF)-1479K (850) | Audio-672K (23) | Peer-Review Report-96K (312) | Answering Reviewers-136K (330) | Received: 09/18/2015 | Revised: 11/19/2015 | Accepted: 12/08/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (10) | Total Visits (28661) | Similar Articles (6) | Timeline of Article Publication (4) | Article Quality Tracking (0) | Cite |

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Terminal ileum gangrene secondary to a type IV paraesophageal hernia

Ching Tsai Hsu, Po Jen Hsiao, Chih Chien Chiu, Jenq Shyong Chan, Yee Fung Lin, Yuan Hung Lo, Chia Jen Hsiao

World J Gastroenterol 22(8):2642-2646. Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2642

Abstract (1389) | Core Tip (1362) | Full Article (HTML) (4440) | Figures (1-2) (579) | Tables (1-1) (538) | Full Article (PDF)-999K (546) | Audio-543K (15) | Peer-Review Report-117K (259) | Answering Reviewers-118K (268) | Received: 06/09/2015 | Revised: 08/05/2015 | Accepted: 10/13/2015 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (15315) | Similar Articles (16) | Timeline of Article Publication (3) | Article Quality Tracking (0) | Cite |

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