Retrospective Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 28, 2016; 22(8): 2621-2629
Published online Feb 28, 2016. doi: 10.3748/wjg.v22.i8.2621
Feasibility of full-spectrum endoscopy: Korea’s first full-spectrum endoscopy colonoscopic trial
Jeong-Yeop Song, Youn Hee Cho, Mi A Kim, Jeong-Ae Kim, Chun Tek Lee, Moon Sung Lee
Jeong-Yeop Song, Youn Hee Cho, Mi A Kim, Jeong-Ae Kim, Chun Tek Lee, Division of Gastroenterology, Department of Internal Medicine, LCT Hospital, Suwon 442-130, South Korea
Moon Sung Lee, Division of Gastroenterology, Department of Internal Medicine, SoonChunHyang University Bucheon Hospital, Bucheon 420-767, South Korea
Author contributions: Song JY, Cho YH, Kim MA, Kim JA, Lee CT and Lee MS contributed equally to this work; Song JY made study conception and design and editing; Cho YH, Kim MA, Kim JA and Lee CT collected the data; Lee MS analyzed and interpreted the data; all authors have read and approved the final version to be published.
Institutional review board statement: This study was reviewed and approved by IRB committee of LeeChunTek (LCT) Hospital.
Informed consent statement: All study participants, or their legal guardian were not required to give informed consent to thisretrospective study because the analysis used anonymous clinical data that were obtained retrospectively after each patient agreed to examination.
Conflict-of-interest statement: Authors have no financial relationships to disclosure.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Moon Sung Lee, MD, Professor, Division of Gastroenterology, Department of Internal Medicine, SoonChunHyang University Bucheon Hospital, 1174 Jung-Dong, Wonmi-Ku, Bucheon 420-767, South Korea. tommymd@daum.net
Telephone: +82-32-6215094 Fax: +82-32-6215080
Received: September 17, 2015
Peer-review started: September 17, 2015
First decision: October 14, 2015
Revised: October 20, 2015
Accepted: November 19, 2015
Article in press: November 19, 2015
Published online: February 28, 2016
Processing time: 161 Days and 3.9 Hours
Abstract

AIM: To evaluate the full-spectrum endoscopy (FUSE) colonoscopy system as the first report on the utility thereof in a Korean population.

METHODS: We explored the efficacy of the FUSE colonoscopy in a retrospective, single-center feasibility study performed between February 1 and July 20, 2015. A total of 262 subjects (age range: 22-80) underwent the FUSE colonoscopy for colorectal cancer screening, polyp surveillance, or diagnostic evaluation. The cecal intubation success rate, the polyp detection rate (PDR), the adenoma detection rate (ADR), and the diverticulum detection rate (DDR), were calculated. Also, the success rates of therapeutic interventions were evaluated with biopsy confirmation.

RESULTS: All patients completed the study and the success rates of cecal and terminal ileal intubation were 100% with the FUSE colonoscope; we found 313 polyps in 142 patients and 173 adenomas in 95. The overall PDR, ADR and DDR were 54.2%, 36.3%, and 25.2%, respectively, and were higher in males, and increased with age. The endoscopists and nurses involved considered that the full-spectrum colonoscope improved navigation and orientation within the colon. No colonoscopy was aborted because of colonoscope malfunction.

CONCLUSION: The FUSE colonoscopy yielded a higher PDR, ADR, DDR than did traditional colonoscopy, without therapeutic failure or complications, showing feasible, effective, and safe in this first Korean trial.

Keywords: Colonoscopy; Colonoscopes; Feasibility studies; Colonic polyps

Core tip: Although many efforts have been made to improve visualization and reduce blind spots in the colonic mucosa, about 10% of the colonic surface remains unobserved during traditional standard forward-view (SFV) colonoscopy. In contrast to the maximum field of view (170°) of SFV colonoscopes, the full-spectrum endoscopy (FUSE) colonoscopy platform affords the endoscopist a high-resolution, 330°“full spectrum” view of the colorectal mucosa. In this first Korean trial, the FUSE colonoscopy yielded a higher polyp, adenoma, diverticulum detection rate without therapeutic failure or complications, to be feasible, effective, and safe.